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| 1 | 20例艾滋病病人经高效联合抗病毒治疗后免疫重建研究显示文摘目的 对接受高效联合抗逆转录病毒治疗 (HAART)后的晚期人类免疫缺陷病毒 1型(HIV 1)感染者的免疫功能重建的可能性和影响因素进行探讨。方法 用开放性前瞻性研究方法 ,对2 0例接受由 1种HIV蛋白酶抑制剂和 2种逆转录酶抑制剂联合组成的HAART的HIV 1病人 ,在治疗前和治疗后 1、3、6、9、12个月时 ,分别测定病人对巨细胞病毒和结核菌抗原的特异性CD4+ T细胞免疫应答反应。结果 经 1年的HAART ,2 0例HIV病人的血浆HIV载量平均下降了 1 5lg拷贝 /ml,CD4+T细胞计数平均上升 6 3个 / μl。开始HAART前 ,仅有 4位患者对特异性抗原有反应 ,治疗 1年后有 10例患者重新恢复了对特异抗原的免疫反应 (P <0 0 0 1)。与无免疫应答者相比 ,免疫应答者血浆HIV载量显著减少 ,并持续维持 ,CD4+ T细胞计数明显增加。结论 HAART治疗能够恢复艾滋病病人CD4+ T细胞抗机会病原体的免疫功能 ,这种恢复与治疗前已破坏的免疫功能严重程度无关 ,而取决于治疗后CD4+ T细胞增加的幅度、病毒复制被控制的程度和持续时间。 | 李太生 Katlama C Autran B | 2003 | 中华检验医学杂志2003，26，5： | 13 |
| 2 | Tantalum Pentoxide ( Ta2 05 ) Thin Films for Advanced Dielectric Applications 显示文摘 | Chaneliero C Autran J L Devine R A B | 1998 | Materials Science and Engineering1998，22，： | 1 |
| 3 | Tantalum pentoxide(Ta2Os) thin films for advanced dielectric applications显示文摘 | CHANELIERE C AUTRAN J L DEVINE R A B BALLAND B | 1998 | Materials Science and Engineering R1998，22，： | 1 |
| 4 | Barriers to a cure for H/V: new ways to target and eradicate HIV-1 reservoirs 显示文摘 | Katlama C Deeks SG Autran B | 2013 | Lancet (London England)2013，381，9883： | 1 |
| 5 | Chromosome 1B - encoded glidins and glutenin subunits in durum wheat : Genetics and relationship to gluten strength 显示文摘 | Pogna N E Autran J C Mellini F | 1990 | Journal of Cereal Science1990，，11： | 1 |
| 6 | Maternal Epigenetic Pathways Control Parental Contributions to Arabidopsis Early Embryogenesis显示文摘 | Daphné Autran Célia Baroux Michael T. Raissig Thomas Lenormand Michael Wittig Stefan Grob Andrea Steimer Matthias Barann Ulrich C. Klostermeier Olivier Leblanc Jean-Philippe Vielle-Calzada Phillip Rosenstiel Daniel Grimanelli Ueli Grossniklaus | 2011 | Cell2011，，5： | 1 |
| 7 | T cell receptor gamma/delta+lymphocyte subsets during HIV infection显示文摘 | Autran B Triebel F Katlama C Rozenbaum W Hercend T Debre P | 1989 | Clin Exp Immunol1989，75，2： | 1 |
| 8 | Barriers to a cure for HIV:new ways to target and eradicate HIV-1 reservoirs显示文摘 | Katlama C Deeks SG Autran B | 2013 | Lancet2013，381，9883： | 1 |
| 9 | Tantalum Pentoxide (Ta200 Thin Films for Advanced Dielectric Applications 显示文摘 | Chaneliere C Autran J L Devine R A B | 1998 | Materials Science and Engineering1998，22，： | 1 |
| 10 | Pasta brownness: an assessment 显示文摘 | Feillet P Autran J C Icard-Verniere C | 2000 | Journal of Cereal Science2000，32，： | 1 |
| 11 | Correlation between breadth of memory HIV-specific cytotoxic T cells, viral load and disease progression in HIV infection显示文摘 | Chouquet C Autran B Gomard E etal | 2002 | AIDS2002，16，18： | 1 |
| 12 | Prediction of baking quality of bread wheats in breeding programs by size-exclusion high-performance liquid chromatograph显示文摘 | Dachkevitch T Autran J C | 1989 | Cereal chemistry1989，66，6： | 1 |
| 13 | 显示文摘 | Chaneliere C Autran J L Devine R A B | 1998 | Mater Sci Eng R1998，22，： | 1 |
| 14 | Post-treatment HIV-1 controllers with a long- term virological remission after the interruption of early ini- tiated antiretroviral therapy ANRS VISCONTI Study 显示文摘 | Sfiez-Ciri6n A Bacchus C Hocqueloux L Avettand-Fenoel V Girault I Lecuroux C Potard V Versmisse P Melard A Prazuck T Descours B Guergnon J Viard JP Boufassa F Lambotte O Goujard C Meyer L Costagliola D Venet A Pancino G Autran B Rouzioux C ANRS VISCONTI Study Group | 2013 | PLoS Pathog2013，9，10： | 1 |
| 15 | Simple and Rapid Method for Purifying Low Molecular Weight Subunits of Glutenin from Wheat显示文摘 | Melas V Morel M H Autran J C | 1994 | Cereal Chemistry1994，71，3： | 1 |
| 16 | Pasta brownness:an assessment显示文摘 | Feillet P Autran J C | | 0，，02： | 1 |
| 17 | Statical evaluation of different technological and biochemical tests for quality assessment in Durum wheat显示文摘 | Autran J C Abecassis J | 1986 | Cereal Chem1986，63，： | 1 |
| 18 | Pasta brownness: an assessment显示文摘 | Feillct P Autran J C Verniere C L | 2000 | Journal of Cereal Science2000，32，： | 1 |
| 19 | Effects of temperature,sonication time,and power settings on size distribution and extractability of total wheat flour proteins as determined by size-exclusion high-performance liquid chromatography 显示文摘 | Morel M H Dehlon P Autran J C | 2000 | Cereal Chemistry2000，77，5： | 1 |
| 20 | Cell numbers and leaf develop- ment in Arabidopsis : a functional analysis of the STRUWWELPETER gene 显示文摘 | Autran D Jonak C Beleram K | 2002 | EMBO Journal2002，21，22： | 1 |
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