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| 1 | 医疗卫生绩效薪酬支付的国际经验及对中国的启示显示文摘为提高医疗质量,过去几十年来世界各国在医疗卫生系统设计并推行了'绩效薪酬支付'项目。这些项目针对不同的对象以及单位和部门进行激励。近年,绩效薪酬被逐渐引入我国医疗卫生系统。本文回顾了国际上主要国家(美国、法国和英国等)在医疗卫生体系内推行的绩效薪酬项目,梳理了各国在项目设计时的共性经验,总结了项目设计时需要考虑的关键要素,包括项目的激励对象、绩效指标、激励方式、绩效基准等,并分析这些要素的优缺点及实施中可能出现的问题,旨在为我国的医疗卫生系统绩效薪酬改革提供参考。 | 蒋舒 阎川 Anne Girault Marie Ferrua Aude Fourcade Philippe Loirat Etienne Minvielle | 2015 | 中国卫生政策研究2015，8，2： | 9 |
| 2 | Pancreatic head cancer in patients with chronicpancreatitis显示文摘BACKGROUND: Chronic pancreatitis (CP) is a risk factor of pancreatic adenocarcinoma (PA). The discovery of a pancreatic head lesion in CP frequently leads to a pancreaticoduo denectomy (PD) which preceded by a multidisciplinary meeting(MM). The aim of this study was to evaluate the relevance between this indication of PD and the definitive pathological results.METHODS: Between 2000 and 2010, all patients with CP who underwent PD for suspicion of PA without any histological proof were retrospectively analyzed. The operative decision has always been made at an MM. The definitive pathological finding was retrospectively confronted with the decision made at an MM, and patients were classified in two groups according to this concordance (group 1) or not (group 2). Clinical and biological parameters were analyzed, preoperative imaging were reread and confronted to pathological findings in order to identify predictive factors of malignant degeneration.RESULTS: During the study period, five of 18 (group 1) patients with CP had PD were histologically confirmed to have PA, and the other 13 (group 2) did not have PA. The median age was52.5 ±8.2 years (gender ratio 3.5). The main symptoms were pain (94.4%) and weight loss (72.2%). There was no patient's death. Six (33.3%) patients had a major complication (ClavienDindo classification ≥3). There was no statistical difference in clinical and biological parameters between the two groups. The rereading of imaging data could not detect efficiently all patients with PA.CONCLUSIONS: Our results confirmed the difficulty in detecting malignant transformation in patients with CP before surgery and therefore an elevated rate of unnecessary PD was found. A uniform imaging protocol is necessary to avoid PD as a less invasive treatment could be proposed. | Aude Merdrignac Laurent Sulpice Michel Rayar Tanguy Rohou Emmanuel Quéhen Ayman Zamreek Karim Boudjema Bernard Meunier | 2014 | Hepatobiliary & Pancreatic Diseases International2014，13，2： | 6 |
| 3 | 矿物油处理对马铃薯长管蚜定向和取食行为的影响(英文)显示文摘大田和实验室研究均表明矿物油的施用可有效降低蚜虫对非持久性病毒的传播。我们分别于矿物油喷施马铃薯植株24h和7d后,调查其对马铃薯长管蚜Macrosiphum euphorbiae行为的影响;采用暗室生测法调查了蚜虫对处理的植物挥发性化合物的反应;采用刺探电位技术(EPG)评价了矿物油处理对蚜虫取食行为的影响。结果表明:矿物油处理导致植物对寄主的引诱作用失效,这种效果至少持续24h。矿物油处理马铃薯植株24h和7d后,蚜虫对处理植株的取食行为发生改变。开始记录至第1次刺探所需时间降低,但只在处理7d后显著降低,提示矿物油处理有助于蚜虫口针的穿刺。然而,流涎阶段以及韧皮部汁液吸食阶段(摄食阶段)显著缩短。本研究中观察到的蚜虫行为的改变不能充分解释施用矿物油的大田中为什么出现7d的保护作用,因此可能还存在其他的机制。 | Arnaud AMELINE Aude COUTY Maria MARTOUB Philippe GIORDANENGO | 2009 | 昆虫学报2009，52，6： | 5 |
| 4 | NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer显示文摘 | Couturier-Maillard Aurélie Secher Thomas Rehman Ateequr Normand Sylvain De Arcangelis Adéle Haesler Robert Huot Ludovic Grandjean Teddy Bressenot Aude Delanoye-Crespin Anne Gaillot Olivier Schreiber Stefan Lemoine Yves Ryffel Bernhard Hot D | 2013 | Journal of Clinical Investigation2013，，2： | 5 |
| 5 | 早期的硫化物饱和并不妨碍斑岩Cu-Au矿的形成显示文摘斑岩型铜(金和钼)矿床提供了世界上约75%的Cu、50%的Mo和20%的Au的产量。该类型矿床通常与汇聚板块边缘的下地壳以及中性火山-侵入岩浆体系相关。然而,尽管经过近十年的研究,目前对造成富矿岩浆体系和贫矿岩浆体系的控制因素仍然不完全清楚。一些研究认为,富矿岩浆比贫瘠岩浆更加富集金属成矿元素,而另一些研究则指出,斑岩型铜矿可以通过正常岩浆形成,并指出岩浆的硫含量、氧逸度、水含量或者上地壳岩浆房的规模都能决定其成矿。 | Du J G Audétat A 袁超(编译) | 2020 | 矿物岩石地球化学通报2020，39，3： | 5 |
| 6 | Microscopic features of colorectal neoplasia in inflammatory bowel diseases显示文摘The risk of developing dysplasia leading to colorectal cancer(CRC)is increased in both ulcerative colitis and Crohn’s disease.The prognosis of CRC may be poorer in patients with inflammatory bowel disease(IBD)than in those without IBD.Most CRCs,in general,develop from a dysplastic precursor lesion.The interpretation by the pathologist of the biopsy will guide decision making in clinical practice:colonoscopic surveillance or surgical management.This review summarizes features of dysplasia(or intraepithelial neoplasia)with macroscopic and microscopic characteristics.From an endoscopic(gross)point of view,dysplasia may be classified as flat or elevated(raised);from a histological point of view,dysplasia is separated into 3 distinct categories:negative for dysplasia,indefinite for dysplasia,and positive for dysplasia with low-or high-grade dysplasia.The morphologic criteria for dysplasia are based on a combination of cytologic(nuclear and cytoplasmic)and architectural aberrations of the crypt epithelium.Immunohistochemical and molecular markers for dysplasia are reviewed and may help with dysplasia diagnosis,although diagnosis is essentially based on morphological criteria.The clinical,epidemiologic,and pathologic characteristics of IBD-related cancers are,in many aspects,different from those that occur sporadically in the general population.Herein,we summarize macroscopic and microscopic features of IBD-related colorectal carcinoma. | Aude Bressenot Virginie Cahn Silvio Danese Laurent Peyrin-Biroulet | 2014 | World Journal of Gastroenterology2014，20，12： | 4 |
| 7 | Quality of life after liver transplantation:State of the art显示文摘Quality of life(QoL) after deceased donor liver transplantation is increasingly recognized as a major outcome parameter. We reviewed recent publications in this rapidly evolving field in order to summarize recent achievements in the field and to define opportunities and perspectives for research and improvement of patient care. QoL does improve after liver transplantation according to a typical pattern. During the first year, there is a significant improvement in QoL. After one year, the improvement does stabilise and tends to decline slightly. In addition to the physical condition, different psychological parameters(such as depression, anxiety, sexual function) and sociodemographic elements(professional state, sex, marital state) seem to impact QoL. Opportunities for further research are the use of dedicated questionnaires and identification of influencing factors for QoL. | Louis Onghena Wouter Develtere Carine Poppe Anja Geerts Roberto Troisi Aude Vanlander Frederik Berrevoet Xavier Rogiers Hans Van Vlierberghe Xavier Verhelst | 2016 | World Journal of Hepatology2016，8，18： | 3 |
| 8 | Comparison of alternative arterial anastomosis site during liver transplantation when the recipient’s hepatic artery is unusable显示文摘Background:Few studies have analyzed outcomes of liver transplantation(LT)when the recipient hepatic artery(HA)was not usable.Methods:We retrospectively evaluated the outcomes of LT performed using the different alternative sites to HA.Results:Between 2002 and 2017,1,677 LT were performed in our institution among which 141(8.4%)with unusable recipient HA were analyzed.Four groups were defined according to the site of anastomosis:the splenic artery(SA group,n=26),coeliac trunk(CT group,n=12),aorta using or not the donor’s vessel(Ao group,n=91)and aorta using a vascular prosthesis(Ao-P group,n=12)as conduit.The median number of intraoperative red blood cell transfusions was significantly increased in the Ao and Ao-P groups(5,5,8.5 and 16 for SA,CT,Ao and Ao-P group respectively,P=0.002),as well as fresh frozen plasma(4.5,2.5,10,17 for the SA,CT,Ao and Ao-P groups respectively,P=0.001).Hospitalization duration was also significantly increased in the Ao and Ao-P groups(15,16,24,26.5 days for the SA,CT,Ao and Ao-P groups respectively,P<0.001).The occurrence of early allograft dysfunction(EAD)(P=0.07)or arterial complications(P=0.26)was not statistically different.Level of factor V,INR,bilirubin and creatinine during the 7th postoperative days(POD)was significantly improved in the SA group.No difference was observed regarding graft(P=0.18)and patient(P=0.16)survival.Conclusions:In case of unusable HA,intraoperative and postoperative outcomes are improved when using the SA or CT compared to aorta. | Jean Marie Beaurepaire Francesco Orlando Giovanni Battista Levi Sandri Caroline Jezequel Edouard Bardou-Jacquet Christophe Camus Mohamed Lakehal Veronique Desfourneaux Aude Merdrignac Elodie Gaignard Alexandre Thobie Damien Bergeat Bernard Meunier Michel Rayar | 2022 | Hepatobiliary Surgery and Nutrition2022，11，1： | 3 |
| 9 | 血浆蛋白粉产品品质分析与比较显示文摘采集市场上占有率较高的14种畜禽血浆蛋白粉,分析比较了产品的色泽、常规成分、凝胶质构、保水性、蛋白质组成、矿物质元素含量等,确定了血浆蛋白粉产品品质现状与差异,为血浆蛋白粉产品品质提升和食品级血浆蛋白粉标准的制定提供数据支持。结果表明:不同企业生产的血浆蛋白粉产品在外观(粉质、色度)和产品品质(粗蛋白、粗灰分、水分、水不溶物含量、凝胶质构和保水性、矿物质元素种类及含量)上存在显著差异(P<0.05),并且饲料级血浆蛋白粉与食品级血浆蛋白粉的差异较大。通过相关性分析发现,提高灰分、Na、Mg、Ca含量可提高血浆蛋白凝胶的弹性,提高Mg、Ca含量可提高血浆蛋白凝胶的保水性。 | 王文婷 侯成立 宋璇 李铮 吴立国 BOGA Laetithia Aude Ingrid 朱杰 张德权 | 2017 | 食品科技2017，42，9： | 2 |
| 10 | Role of Fatty Acid Binding Proteins and Long Chain Fatty Acids in Modulating Nuclear Receptors and Gene Transcription显示文摘 | Friedhelm Schroeder Anca D. Petrescu Huan Huang Barbara P. Atshaves Avery L. McIntosh Gregory G. Martin Heather A. Hostetler Aude Vespa Danilo Landrock Kerstin K. Landrock H. Ross Payne Ann B. Kier | 2008 | Lipids2008，，1： | 2 |
| 11 | First characterization of endophytic Corynespora cassiicola isolates with variant cassiicolin genes recovered from rubber trees in Brazil显示文摘Corynespora cassiicola is the causal agent of Corynespora Leaf Fall(CLF)disease.CLF is one of the most important fungal diseases of rubber trees in Asia and Africa but disease outbreaks have not been reported in South America.Cassiicolin,a small cysteine-rich glycoprotein secreted by the pathogenic C.cassiicola isolate CCP,was previously identified as a potential disease effector in rubber tree.Recently,the cassiicolin-encoding gene(Cas1)was characterized and shown to be expressed in the early phase of infection.In this study,we investigated whether previously undetected strains of C.cassiicola are present in South American rubber plantations by examining the fungal endophyte population found in asymptomatic rubber tree leaves.Four isolates were identified as C.cassiicola.Genes encoding new forms of the cassiicolin precursor protein(Cas3 and Cas4)were identified from these isolates.Three of four isolates were able to induce symptoms on the cultivar they were isolated from in a detached leaf assay,with different kinetics and intensities.One isolate had the same pathogenicity profile as the pathogenic isolate CCP;the other two isolates developed symptoms late during the course of infection,suggesting saprotrophic capabilities.However,no Cas3 or Cas4 transcripts could be detected upon inoculation with the endophytic isolates,whereas the reference gene Cas1 was expressed upon inoculation with the CCP isolate.This work demonstrated that C.cassiicola is present in South America in an endophytic form and that it may evolve from an endophytic to a saprophytic or even potentially pathogenic life style. | Marine Déon Ana Scomparin Aude Tixier Carlos R.R.Mattos Thierry Leroy Marc Seguin Patricia Roeckel-Drevet Valérie Pujade-Renaud | 2012 | Fungal Diversity2012，，3： | 2 |
| 12 | Appadtion of the NAC Transcription Factors Predates the Emergence of Land Plants显示文摘 | Aude Maugarny-Cales Beatriz Gonqalves Stefan Jouannic Michael Melkonian Gane Ka-Shu Wonge Patrick Laufs | 2016 | Molecular Plant2016，9，9： | 2 |
| 13 | Chapter 2 Building the gist of a scene: the role of global image features in recognition显示文摘 | Aude Oliva Antonio Torralba | 2006 | Progress in Brain Research2006，，： | 2 |
| 14 | Modeling the Shape of the Scene: A Holistic Representation of the Spatial Envelope显示文摘 | Aude Oliva Antonio Torralba | 2001 | International Journal of Computer Vision2001，，3： | 2 |
| 15 | Factors Associated With Diagnosis of Obscure Gastrointestinal Bleeding by Video Capsule Enteroscopy显示文摘 | Lucie Lepileur Xavier Dray Michel Antonietti Isabelle Iwanicki–Caron Sébastien Grigioni Ulriikka Chaput Aude Di–Fiore Raied Alhameedi Philippe Marteau Philippe Ducrotté Stéphane Lecleire | 2012 | Clinical Gastroenterology and Hepatology2012，，12： | 2 |
| 16 | Localization of laminin,fibronectin,E-caderin,and integrins in endometrium and endometriosis显示文摘 | Aude Beliard M D Jacques Donnez P H D | 1997 | Fertil Steril1997，67，： | 1 |
| 17 | Fischer-Tropsch synthesis:Cobalt particle size and support effects on intrinsic activity and product distribution显示文摘 | Oyvind B Pascal D C D AUD I S | 2008 | J Catal2008，259，2： | 1 |
| 18 | Contribution to the understanding of fouling build-up:during microfiltration of wines 显示文摘 | Aude Vemhet Damien Cartalade Michel Moutounet | 2003 | Journal of Membrane Science2003，211，： | 1 |
| 19 | Fabrication of porous polysaccharide-based scaffolds using a combined freeze-drying/cross-linking process显示文摘 | Aude Autissier Catherine Le Visage Cécile Pouzet Frédéric Chaubet Didier Letourneur | 2010 | Acta Biomaterialia2010，，9： | 1 |
| 20 | Electrical Reconnection After Pulmonary Vein Isolation Is Contingent on Contact Force During Initial Treatment: Results From the EFFICAS I Study显示文摘 | Petr Neuzil Vivek Y. Reddy Josef Kautzner Jan Petru Dan Wichterle Dipen Shah Hendrik Lambert Aude Yulzari Erik Wissner Karl-Heinz Kuck | 2013 | Circulation: Arrhythmia and Electrophysiology2013，，： | 1 |
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