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| 1 | Essential oils as alternatives to antibiotics in swine production显示文摘This review article summarizes the efficacy, feasibility and potential mechanisms of the application of essential oils as antibiotic alternatives in swine production.Although there are numerous studies demonstrating that essential oils have several properties, such as antimicrobial, antioxidative and antiinflammatory effects, feed palatability enhancement and improvement in gut growth and health, there is still a need of further investigations to elucidate the mechanisms underlying their functions.In the past,the results has been inconsistent in both laboratory and field studies because of the varied product compositions, dosages, purities and growing stages and conditions of animals.The minimal inhibitory concentration(MIC) of essential oils needed for killing enteric pathogens may not ensure the optimal feed intake and the essential oils inclusion cost may be too high in swine production.With the lipophilic and volatile nature of essential oils, there is a challenge in effective delivery of essential oils within pig gut and this challenge can partially be resolved by microencapsulation and nanotechnology.The effects of essential oils on inflammation, oxidative stress, microbiome, gut chemosensing and bacterial quorum sensing(QS) have led to better production performance of animals fed essential oils in a number of studies.It has been demonstrated that essential oils have good potential as antibiotic alternatives in feeds for swine production.The combination of different essential oils and other compounds(synergistic effect) such as organic acids seems to be a promising approach to improve the efficacy and safety of essential oils in applications.High-throughput systems technologies have been developed recently,which will allow us to dissect the mechanisms underlying the functions of essential oils and facilitate the use of essential oils in swine production. | Faith A.Omonijo Liju Ni Joshua Gong Qi Wang Ludovic Lahaye Chengbo Yang | 2018 | Animal Nutrition2018，，2： | 24 |
| 2 | Effect of dietary supplementation with protease on growth performance,nutrient digestibility, intestinal morphology, digestive enzymes and gene expression of weaned piglets显示文摘This study was conducted to investigate the effect of dietary protease supplementation on the growth performance, nutrient digestibility, intestinal morphology, digestive enzymes and gene expression in weaned piglets. A total of 300 weaned piglets(21 days of age Duroc x Large White x Landrace; initial BW = 6.27 ± 0.45 kg) were randomly divided into 5 groups. The 5 diets were: 1) positive control diet(PC), 2) negative control diet(NC), and 3) protease supplementations, which were 100, 200, and 300 mg per kg NC diet. Results indicated that final BW, ADG, ADFI, crude protein digestibility, enzyme activities of stomach pepsin, pancreatic amylase and trypsin, plasma total protein, and intestinal villus height were higher for the PC diet and the supplementations of 200 and 300 mg protease per kg NC diet than for the NC diet(P < 0.05). Supplementations of 200 and 300 mg protease per kg NC diet significantly increased the ratio of villus height to crypt depth(VH:CD) of duodenum, jejunum and ileum compared with NC diet(P < 0.05). Feed to gain ratio, diarrhea index, blood urea nitrogen, and diamine oxidase were lower for the PC diet and supplementations of 200 and 300 mg protease per kg NC diet than for the NC diet(P < 0.05). Piglets fed the PC diet had a higher peptide transporter 1(PepTl) mRNA abundance in duodenum than piglets fed the NC diet(P < 0.05), and supplementations of 100, 200 and 300 mg protease per kg NC diet increased the PepTl mRNA abundance in duodenum(P < 0.05) comparing with the NC diet. Piglets fed the PC diet had a higher b0,+AT mRNA abundance in jejunum than piglets fed the NC diet(P < 0.05), and supplementations of 200 and 300 mg protease per kg NC diet increased the b0,+AT mRNA abundance in jejunum and ileum comparing with the NC diet(P < 0.05). In summary, dietary protease supplementation increases growth performance in weaned piglets, which may contribute to the improvement of intestinal development, protein digestibility, nutrient transport efficiency, and health status of piglets when fed low digestible protein sources. | Jianjun Zuo Baoming Ling Lina Long Tiejun Li Ludovic Lahaye Chengbo Yang Dingyuan Feng | 2015 | Animal Nutrition2015，，4： | 18 |
| 3 | 橡胶树品种热研88-13易碎胚性愈伤组织的诱导及其植株再生显示文摘以高产优质橡胶品种热研88-13的幼嫩种子内珠被为外植体材料,对愈伤组织诱导培养基和继代培养基中的影响因素如植物生长调节剂的种类和浓度、钙离子浓度等进行了研究。经过连续6个月的继代选择培养,逐渐诱导出易碎的胚性愈伤组织,适宜的易碎胚性愈伤组织诱导培养基为:MH基本成分,添加0.5 mg/L KT,2.0 mg/L 2,4-D,11.0 mmol/L CaCl2,80.0 g/L蔗糖和2.0 g/L Phytagel。组织学切片证明长期继代培养的易碎胚性愈伤组织维持了胚性的状态。取继代培养2 a多的易碎胚性愈伤组织诱导体细胞胚的形成,得到了16 000多个体细胞胚。将这些胚进行进一步的转移培养,得到了115株再生植株。 | 李哲 孙爱花 黄天带 周权男 戴雪梅 黄华孙 林位夫 Ludovic Lardet Pascal Montoro Marc-Philippe Carron | 2010 | 热带作物学报2010，31，12： | 7 |
| 4 | A Parametric Genetic Algorithm Approach to Assess Complementary Options of Large Scale Wind-solar Coupling显示文摘The transitional path towards a highly renewable power system based on wind and solar energy sources is investigated considering their intermittent and spatially distributed characteristics. Using an extensive weather-driven simulation of hourly power mismatches between generation and load, we explore the interplay between geographical resource complementarity and energy storage strategies. Solar and wind resources are considered at variable spatial scales across Europe and related to the Swiss load curve, which serve as a typical demand side reference. The optimal spatial distribution of renewable units is further assessed through a parameterized optimization method based on a genetic algorithm. It allows us to explore systematically the effective potential of combined integration strategies depending on the sizing of the system, with a focus on how overall performance is affected by the definition of network boundaries. Upper bounds on integration schemes are provided considering both renewable penetration and needed reserve power capacity. The quantitative trade-off between grid extension, storage and optimal wind-solar mix is highlighted.This paper also brings insights on how optimal geographical distribution of renewable units evolves as a function of renewable penetration and grid extent. | Tim Mareda Ludovic Gaudard Franco Romerio | 2017 | IEEE/CAA Journal of Automatica Sinica2017，4，2： | 7 |
| 5 | NOD2-mediated dysbiosis predisposes mice to transmissible colitis and colorectal cancer显示文摘 | Couturier-Maillard Aurélie Secher Thomas Rehman Ateequr Normand Sylvain De Arcangelis Adéle Haesler Robert Huot Ludovic Grandjean Teddy Bressenot Aude Delanoye-Crespin Anne Gaillot Olivier Schreiber Stefan Lemoine Yves Ryffel Bernhard Hot D | 2013 | Journal of Clinical Investigation2013，，2： | 5 |
| 6 | Sensory Evaluation in Characterization of Fabric Hand显示文摘This paper is divided in two parts. The first part presents optimized methods for formalizing and analyzing sensory data provided by different panels on fabric hand evaluation. For achieving this challenge, we first transform each evaluation into fuzzy sets and we submit criteria for assessing the fabric hand evaluation given by experts as well as criteria for computing the distances between different panels and the employed linguistic terms in different evaluation spaces. This sensory data analysis allows us to check expert’s and customer’s behaviors on fabric hand. Based on this first procedure about formalization and sensory data analysis, we can study the relationships between sensory evaluation given by different experts for a fabric set and the objective data set provided by appropriate measurements. From a set of fabric samples, a database with nearly 10 parameters characterizing the touch handle is built. This way of evaluation is performed by measuring a set of physical parameters on fabrics. Those parameters constitute the input variables of our model. For the textile industry, the major difficulty lies in the fact that the performed measurements on fabrics lead to precise numerical data describing indirectly fabric hand but their relationships with the evaluation given by experts should be exploited. We implement a fuzzy model which predicts the marks reached for a set of linguistic terms. The effectiveness of these methods and criteria is shown through a number of knitted cotton fabrics. | Ludovic Koehl 周斌 ZENG Xian-yi 丁永生 | 2004 | Journal of Donghua University(English Edition)2004，21，3： | 4 |
| 7 | 蛋白酶在动物生产中的应用显示文摘蛋白原料价格昂贵、环境问题以及蛋白酶相对其他饲料添加剂具有更好的可获得性,使蛋白酶在动物营养中的应用也越来越受到高度关注。蛋白酶能够提高单胃动物对蛋白质、多肽及氨基酸的消化能力,同时改善单胃动物消化生理功能。在家禽营养中,使用蛋白酶可提高家禽的生产性能,或者在使用相对便宜的配方饲料喂养家禽时维持家禽的生产性能。蛋白酶在猪营养中的应用可促进断奶仔猪的生长,减少某些饲料原料中抗营养因子的负面影响。在水产养殖中应用蛋白酶能保持或改善水产动物生产性能的前提下,通过降低鱼粉用量、应用植物蛋白原料及其它非常规植物蛋白原料来降低饲料成本。 | Ludovic Lahaye Robert Gauthier 熊玲玲 | 2011 | 饲料与畜牧(新饲料)2011，，7： | 4 |
| 8 | 橡胶树热研88-13品种珠心易碎愈伤组织诱导及其胚状体发生显示文摘以橡胶树热研88-13品种的幼嫩种子的珠心组织为材料,诱导出胚性愈伤组织。对胚性愈伤组织诱导培养基、继代培养基中不同的影响因素如植物生长调节剂的种类和浓度、钙离子浓度等进行了研究,筛选到了合适的影响因素。经过连续5个月的继代选择培养,逐渐诱导出易碎的胚性愈伤组织。对易碎胚性愈伤组织进行了长期继代培养。组织学切片证明长期继代培养的愈伤组织维持了胚性的状态。取继代培养了2年多的橡胶树热研88-13品种的珠心易碎胚性愈伤组织诱导胚状体,得到了186个胚状体,正在诱导植株再生。 | 李哲 戴雪梅 孙爱花 黄天带 周权男 黄华孙 林位夫 Ludovic Lardet Pascal Montoro Marc-Philippe Carron | 2010 | 热带生物学报2010，1，4： | 3 |
| 9 | Tunica albuginea allograft: a new model of LaPeyronie's disease with penile curvature and subtunical ossification显示文摘LaPeyronie 的疾病(PD ) 的 pathophysiology 被认为是 multifactorial,包含愈合的基因倾向,损伤,发炎和改变的创伤。然而,这些因素还没用动物模型被验证了。在这研究,我们介绍了 tunica albuginea allograft 获得的一个新模型。40 的一个总数, 16-week-old 男性老鼠被使用。这些, 8 只老鼠用作控制并且经历了 10 ×有随后的 autografting 的 2-mm-wide tunical 切除,而留下 32 与另一只老鼠的 tunica 与缺点的 grafting 经历了一样的切除。词法、功能测试在 grafting 以后在 1, 3, 7 和 12 个星期被执行。Intracavernous 压力,阴茎弯曲的度和有弹性的纤维长度为在 allograft 和控制组之间的比较被评估。纸巾为组织学的检查被获得。阴茎弯曲作为与控制老鼠相比在 allografted 老鼠是显著地更大的。可勃起的功能在所有老鼠被维持,除了在在 12 个星期估计的那些。弹力素纤维长度作为与控制相比在 allografted tunica 被减少。SMAD2 表示在 allograft 的内部部分被检测,并且 collagen-II- 和 osteocalcin 积极的房间也被注意。在老鼠的 Tunica albuginea (TA ) allograft 是 PD 的一个优秀模型。在 12 个星期和在 TA 的内部层的骨化的存在以后的弯曲的坚持类似于与 PD 在人观察的那些。用这个动物模型的确认研究将为有效治疗学的干预帮助 PD pathophysiology 的理解。 | Ludovic Ferretti Thomas M Fandel Xuefeng Qiu Haiyang Zhang Hazem Orabi Alex K Wu Lia Banie Guifang Wang Guiting Lin Ching-Shwun Lin Tom FLue | 2014 | Asian Journal of Andrology2014，16，4： | 3 |
| 10 | Therapeutic efficiency of everolimus and lapatinib in xenograft model of human colorectal carcinoma with KRAS mutation显示文摘 | Céline Chu Marie‐Sophie No?l‐Hudson Valérie Boige Diane Goéré Sylvie Marion Mélanie Polrot Ludovic Bigot Patrick Gonin Robert Farinotti Laurence Bonhomme‐Faivre | 2013 | Fundamental & Clinical Pharmacology2013，，4： | 2 |
| 11 | A review of some methodological developments on full waveform inversion tackled in the SEISCOPE group显示文摘Full waveform inversion(FWI)is a data-fitting inverse problem aiming to delineate high-resolution quantitative images of the Earth.While its basic principle has been proposed in the eighties,the approach has been significantly developed and applied to2Dand 3Dproblems at various scales for the last fifteen years.Despite these successes,FWI is still facing some issues for applications in complex geological setups because of some lack of robustness and automatic workflow,while being computationally intensive.In this paper,after a short review of the basic FWI formulation and analysis of the FWI gradient,three recent methodological developments performed in the frame of the SEISCOPE project are presented.First,an algorithmic development is presented as a low-memory and computationally efficient approach for building the time-domain FWI gradient in 3Dviscous media.Second,a reformulation of FWI is performed to handle reflections in their tomography regime while still using the diving waves,leading to the joint full waveform inversion(JFWI)approach.Finally,an optimal transport approach is proposed as an alternative to the classical difference-based misfit for mitigating the cycle-skipping issue. | Romain BROSSIER Ludovic METIVIER Jean VIRIEUX YANG Pengliang ZHOU Wei | 2017 | 石油物探2017，56，1： | 2 |
| 12 | Activation of mitochondrial μ-calpain increases AIF cleavage in cardiac mitochondria during ischemia–reperfusion显示文摘 | Qun Chen Melanie Paillard Ludovic Gomez Thomas Ross Ying Hu Aijun Xu Edward J. Lesnefsky | 2011 | Biochemical and Biophysical Research Communications2011，，4： | 2 |
| 13 | The impact of colour on Website appeal and users’ cognitive processes显示文摘 | Nathalie Bonnardel Annie Piolat Ludovic Le Bigot | 2010 | Displays2010，，2： | 1 |
| 14 | Quality Evaluation of Sugar Beet ( Beta Vulgaris ) by Near-Infrared Spectroscopy 显示文摘 | Yvers Roggo Ludovic Duponchel Jean-pierre Huvenne | 2004 | J Agric Food chem2004，52，5： | 1 |
| 15 | Industrial water management by multiobjective optimization :from individual to collective solution through eco-industrial parks 显示文摘 | MARIANNE BOIX LUDOVIC MONTASTRUC LUC PIBOULEAU | 2012 | Journal of Cleaner Production2012，22，： | 1 |
| 16 | 低成本姿态控制敏感器的新家族显示文摘本文介绍满足人造卫星姿态测量要求的新一代光学敏感器的发展状况。这些敏感器包括:一种新型两轴全静态红外地球敏感器(现已通过鉴定)。它用来测量三轴稳定卫星相对于地平线的俯仰与滚动姿态;一种新型多功能、全自动、低成本的星跟踪器。这种星跟踪器(现已通过鉴定)为姿态控制分系统提供三轴姿态和卫星角速度信息;一种用来测量卫星俯仰与滚动姿态角的新型太阳敏感器。它质量很轻,价格很便宜。 | Daniel Fischer Rene.Priam Ludovic Blarre Didier Vilaire 郑克隆 | 2003 | 控制工程(北京)2003，，2： | 1 |
| 17 | On the flexibility of an eco-industrial park (EIP) for managing industrial water 显示文摘 | LUDOVIC MONTASTRUC MARIANNE BOIX LUC PIBOULEAU | 2013 | Journal of Cleaner Production2013，43，： | 1 |
| 18 | Diagnostic and prognostic impact of 18F-FDG PET/CT in follicular lym- phoma显示文摘 | Ludovic Le Dortz Sophie De Guibert Sahar Bayat | 2010 | Eur J Nucl Med Mol Imaging2010，37，12： | 1 |
| 19 | Use of HepG2 cell line for direct or indirect mutagens screening: comparative investigation between comet and micronucleus assays显示文摘 | Isabelle Valentin-Severin Ludovic Le Hegarat Jean-Claude Lhuguenot Anne-Marie Le Bon Marie-Christine Chagnon | 2003 | MutRes-Genetic Toxicology and Environmental Mutagenesis2003，，1： | 1 |
| 20 | Liquid holdup and pressure drop determination in structured packing with CFD simulations显示文摘 | Ludovic Raynal Cb_ristophe Boyer Jean-Pierre Ballaguet | 2004 | The Canadian Journal of Chemical Engineering2004，82，5： | 1 |
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