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| 1 | Predictive factors of survival in patients treated with definitive chemoradiotherapy for squamous cell esophageal carcinoma显示文摘瞄准:学习的目的是与食道的癌(LASCOC ) 与权威的 chemoradiotherapy (CRT ) 对待的局部地先进的有鳞的房间在病人评估幸存的预兆的因素政体基于 5FU/CDDP 联合。方法:有用在 1994 和 2000 之间的 5FU/CDDP 联合与权威的 CRT 对待的 LASCOC 的所有病人回顾地被包括。对 CRT 的临床的完全的反应(CCR ) 被食道的内视镜检查法和 CT 扫描估计在 CRT 结束以后的 2 瞬间。幸存的预示的因素用 univariate 被估计,多,由艇长回归的变量分析当模特儿。结果:116 个病人的一个总数在学习被包括。到 CRT 的 CCR 在 86/116 (74.1%) 被观察。中部的幸存是 20 瞬间(范围 2-114 ) , 5 年的幸存是 9.4% 。到 CRT 的应答者病人的中部的幸存在非应答者病人作为与 9 瞬间(范围 2-81 ) 相比是 25 瞬间(范围 3-114 )(P <
0.001 ) 。在 univariate 分析,幸存与 CCR 被联系(P <
0.001 ) ,表演地位 <
2 (P = 0.01 ) ,瘤长度 <
6 厘米(P = 0.045 ) 并且 10% 在意义的限制的重量损失 <
(P = 0.053 ) 。在里面多变量分析,幸存对 CCR 依赖(P <
0.0001 ) ,重量损失 <
10%(P = 0.034 ) 并且表演 <
2 (P = 0.046 ) 。结论:我们的结果建议在有与权威的 CRT 对待的 LASCOC 的病人的那幸存被相关到 CCR,重量损失并且表演地位。 | Frédéric Di Fiore Stéphane Lecleire Olivier Rigal Marie-Pierre Galais Emmanuel Ben Soussan Isabelle David Bernard Paillot Jacques-Henri Jacob Pierre Michel | 2006 | World Journal of Gastroenterology2006，12，26： | 13 |
| 2 | Factors Associated With Diagnosis of Obscure Gastrointestinal Bleeding by Video Capsule Enteroscopy显示文摘 | Lucie Lepileur Xavier Dray Michel Antonietti Isabelle Iwanicki–Caron Sébastien Grigioni Ulriikka Chaput Aude Di–Fiore Raied Alhameedi Philippe Marteau Philippe Ducrotté Stéphane Lecleire | 2012 | Clinical Gastroenterology and Hepatology2012，，12： | 2 |
| 3 | Duodenal intraepithelial T lymphocytes in patients with functional dyspepsia显示文摘AIM: To quantify the intraepithelial lymphocytes (IELs) and to document the membrane expression of CD4, CD8, TCRγδ and adhesion and/or activation-associated molecules (CD103, CD28, CD44, CD69, HLA-DR, CD95/ Fas) in the duodenal mucosa of patients with functional dyspepsia (FD) in order to provide arguments for an immunological process in FD. METHODS: Twenty-six FD patients according to Rome Ⅱ criteria (20 were H pylori negative) were studied and compared to 12 healthy adults. IELs were isolated from five duodenal biopsy samples, then quantified by microscopy and flow cytometry while the membrane phenotypes were determined by cytofluorometry. RESULTS: Duodenal histological examination was normal. In H pylori negative patients, the number of IELs was not different from that in healthy controls. Median percentage expression of CD4, CD8, or TCRγδ and CD103, CD44, CD28, CD69 on CD3+ IELs, among the adhesion/activation associated molecules tested, was not different from that in healthy controls. In contrast, the median percentage expression of CD95/ Fas [22 (9-65) vs 45 (19-88), P = 0.03] and HLA- DR expressing CD3+ IELs [4 (0-30) vs 13 (4-42), P = 0.04] was significantly lower in the H pylori negative FD group than in healthy controls, respectively. The number of IELs was significantly greater in H pylori positive FD patients than in healthy controls [median ratiofor 100 enterocytes 27.5 (6.7-62.5) vs 10.8 (3-33.3), P = 0.02] due to a higher number of CD8+ CD3+ IELs. CONCLUSION: In H pylori negative FD patients, the phenotypic characterization of IELs suggests that we cannot exclude a role of IELs in FD. | Gilles Gargala Stéphane Lecleire Arnaud Franois Serge Jacquot Pierre Déchelotte Jean Jacques Ballet Loic Favennec Philippe Ducrotté | 2007 | World Journal of Gastroenterology2007，13，16： | 2 |
| 4 | Baseline nutritional status is predictive of response to treatment and survival in patients treated by definitive chemoradiotherapy for a locally advanced esophageal cancer 显示文摘 | Di Fiore F Lecleire S Pop D | 2007 | Am J Gastroenterol2007，102，： | 1 |
| 5 | Baseline nutritional status is predictive of response to treatment and survival in patients treated by definitive chemoradiotherapy for a locally advanced esophageal cancer显示文摘 | Di FF Lecleire S Pop D | 2007 | Am J Gastroen- terol2007，102，11： | 1 |
| 6 | The relation- ships between nutrients, cyanobacterial toxins and the microbial com- munity in Talhu (Lake Tai), China显示文摘 | WILHELM SW FARNSLEY SE LECLEIR GR | 2011 | Harmful Algae2011，10，： | 1 |
| 7 | Endoscopic markers of villous atrophy are not useful for the detection of celiac disease in patients with dyspeptic symptoms显示文摘 | S. Lecleire F. Di Fiore M. Antonietti G. Savoye F. Lemoine F. Le Pessot E. Lerebours P. Ducrotté | 2006 | Endoscopy2006，，07： | 1 |
| 8 | Enteral glutamine infusion modulates ubiquitination of heat shock proteins, Grp-75 and Apg-2, in the human duodenal mucosa显示文摘 | Julien Bertrand Alexis Goichon Philippe Chan Saida Azhar Stéphane Lecleire Nathalie Donnadieu David Vaudry Anne-Fran?oise Cailleux Pierre Déchelotte Mo?se Co?ffier | 2014 | Amino Acids2014，，4： | 1 |
| 9 | Prior chemoradiotherapy is associated with a higher life-threatening complication rate after palliative insertion of metal stents in patients with oesophageal cancer显示文摘 | Lecleire S Di Fiore F Ben-Soussan E | 2006 | Aliment Pharmacol Ther2006，23，12： | 1 |
| 10 | Lugol chromo- endoscopy versus narrow band imaging for endoscopic screening of esophageal squamous-cell carcinoma in patients with a history of cured esophageal cancer: a feasibility study 显示文摘 | Lecleire S Antonietti M Iwanicki-Caron I | 2011 | Dis Esophagus2011，24，6： | 1 |
| 11 | Nonoperable pa- tients with superficial esophageal cancer treated by photodynamic therapy after chemoradiotherapy have more severe complicationsthan patients treated in primary intent显示文摘 | LECLEIRE S DI FF ANTONIETTI M | 2008 | Am J Gastroenterol2008，103，9： | 1 |
| 12 | Mallory-Weiss syndrome : diag- nosis and treatment 显示文摘 | Lecleire S Antonietti M Ducmtt P | 2010 | Presse Med2010，39，6： | 1 |
| 13 | Undemutrition is predictive of early mortality after palliative self-expanding metal stent insertion in patients with inoperable or recurrent esophageal cancer 显示文摘 | Lecleire S Di Fiore F Antonietti My | 2006 | Gastrointest Endosc2006，64，4： | 1 |
| 14 | Baseline nutritional status is predictive of response to treatment and survival in patients treated by definitive chemoradiotherapy for a locally advanced esophageal cancer 显示文摘 | Di Fiore F Lecleire S Pop D | 2007 | Am J C astroentero12007，102，11： | 1 |
| 15 | Fully covered self-expanding metal stents for benign colonic strictures显示文摘 | G. Vanbiervliet P. Bichard J.-F. Demarquay E. Ben-soussan S. Lecleire K. Barange J.-M. Canard H. Lamouliatte E. Fontas M. Barthet T. Ponchon J.-C. Saurin | 2013 | Endoscopy2013，，01： | 1 |
| 16 | Combined enteral in- fusion of glutamine, carbohydrates, and antioxidants modulates gut protein metabolism in humans 显示文摘 | Coeffier M Claeyssens S Lecleire S | 2008 | Am J Clin Nutr2008，88，5： | 1 |
| 17 | Diagnostic impact of routine colonoscopy following acute diverticulitis:a multicenter study in808 patients and controls显示文摘 | Lecleire S Nahon S Alatawi A | 2014 | United European Gastroenterol J2014，2，4： | 1 |
| 18 | Prior chemoradio- therapy is associated with a higher life - threatening complicationrate after palliative insertion of metal stents in patients with oeso- phageal cancer 显示文摘 | Lecleire S Di FF Ben - Soussan E | 2006 | Aliment Pharmacol Ther2006，23，12： | 1 |
| 19 | Factors Associated With Diagnosis of Obscure Gastrointestinal Bleeding by Video Capsule Enteroscopy显示文摘 | Lucie Lepileur Xavier Dray Michel Antonietti Isabelle Iwanicki–Caron Sébastien Grigioni Ulriikka Chaput Aude Di–Fiore Raied Alhameedi Philippe Marteau Philippe Ducrotté Stéphane Lecleire | 2012 | Clinical Gastroenterology and Hepatology2012，，12： | 1 |
| 20 | Lugol chromo-endoscopy versus narrow band imaging for endoscopic screening ofesophageal squamous-cell carcinoma in patients with a history of curedesophageal cancer : a feasibility study 显示文摘 | Lecleire S Antonietti M Iwanicki-Caron I | 2011 | Dis Esophagus2011，24，41： | 1 |
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