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| 1 | Imaging evaluation of traumatic thoracolumbar spine injuries: Radiological review显示文摘Spine fractures account for a large portion of musculoskeletal injuries worldwide. A classification of spine fractures is necessary in order to develop a common language for treatment indications and outcomes. Several classification systems have been developed based on injury anatomy or mechanisms of action, but they have demonstrated poor reliability, have yielded little prognostic information, and have not been widely used. For this reason, the Arbeitsgemeinschaftfür Osteosynthesefragen(AO) committee has classified thorocolumbar spine injuries based on the pathomorphological criteria into3 types(A: Compression; B: Distraction; C: Axial torque and rotational deformity). Each of these types is further divided into 3 groups and 3 subgroups reflecting progressive scale of morphological damage and the degree of instability. Because of its highly detailed sub classifications, the AO system has shown limited interobserver variability. It is similar to its predecessors in that it does not incorporate the patient's neurologic status.The need for a reliable, reproducible, clinically relevant, prognostic classification system with an optimal balance of ease of use and detail of injury description contributed to the development of a new classification system, the thoracolumbar injury classification and severity score(TLICS). The TLICS defines injury based on three clinical characteristics: injury morphology, integrity of the posterior ligamentous complex, and neurologic status of the patient. The severity score offers prognostic information and is helpful in decision making about surgical vs nonsurgical management. | Shivanand Gamanagatti Deepak Rathinam Krithika Rangarajan Atin Kumar Kamran Farooque Vijay Sharma | 2015 | World Journal of Radiology2015，7，9： | 18 |
| 2 | Acute femoral artery pseudoaneurysm due to lesser trochanter fragment: an unusual complication of an intertrochanteric fracture显示文摘大腿骨的动脉的假动脉瘤是 intertrochanteric 骨折的稀罕复杂并发症。大多数这些状况由于因医生之治疗而引的损伤或损伤本身并且被打乱的骨头碎片很少引起。这里,我们报导从更小的 trochanter 碎片的尖铁与表面的大腿骨的动脉的 pseudoaneurysm 尖锐地介绍了的一个 72 岁的人的一个案例。有盖住的 stent 的 pseudoaneurysm 的经皮的 endovascular 处理在一个迫切基础上被承担。五天以后,病人被操作在之上,更小的 trochanter 碎片通过一个前面的切口被切除, intertrochanteric 骨折用动态新潮的螺丝钉被修理。破裂在 10 个星期被统一。在 one-year’s 后续,没有接枝相关的复杂并发症。这个案例说明那有代替的更小的 trochanter 碎片的 intertrochanteric 破裂能与流血和大腿骨的动脉的 pseudoaneurysm 尖锐地介绍。 | Gaurav Sharma Ravijot Singh Atin Kumar Vijay Sharma Kamran Farooque | 2013 | Chinese Journal of Traumatology2013，16，5： | 11 |
| 3 | Triple plating of tibia in a complex bicondylar tibial plateau fracture显示文摘高精力的胫骨的高原骨折为整形外科的外科医生提出重要挑战和困难。胫骨的高原的骨折包含主要重量适用连接并且可以改变膝 kinematics。近似胫骨的关节的表面,手足轴(手足排列) 的恢复和允许早联合的运动的稳定的固定的解剖重建是处理的目标。在胫骨的高原折断的复杂 bicondylar 的情况下,孤立侧面的 plating 经常与内翻足 malalignment 被联系,更好的结果通过双切口与双边的 plating 被获得了。然而,有时,胫骨的高原折断的 bicondylar 的一种复杂类型在中间的高原在哪个让 biplaner 象 sagittal 飞机一样在以后的花冠飞机断裂被遇到。在如此的破裂,与在两架飞机支持修理中间的高原是必要的。近似胫骨的一个如此的破裂模式通过双 posteromedial 由三倍的 plating 设法,在前面偏一边的切口在这类损害,外科的途径和管理的机制上与强调在这份情况报告被讨论。 | Atin Jaiswal Naiman Deepak Kachchhap Yashwant S Tanwar Birendra Kumar Sachin K Yadav | 2014 | Chinese Journal of Traumatology2014，17，3： | 10 |
| 4 | Blunt pancreatic trauma: A persistent diagnostic conundrum?显示文摘Blunt pancreatic trauma is an uncommon injury but has high morbidity and mortality. In modern era of trauma care, pancreatic trauma remains a persistent challenge to radiologists and surgeons alike. Early detection of pancreatic trauma is essential to prevent subsequent complications. However early pancreatic injury is often subtle on computed tomography(CT) and can be missed unless specifically looked for. Signs of pancreatic injury on CT include laceration, transection, bulky pancreas, heterogeneous enhancement, peripancreatic fluid and signs of pancreatitis. Pan-creatic ductal injury is a vital decision-making parameter as ductal injury is an indication for laparotomy. While lacerations involving more than half of pancreatic parenchyma are suggestive of ductal injury on CT, ductal injuries can be directly assessed on magnetic resonance imaging(MRI) or encoscopic retrograde cholangio-pancreatography. Pancreatic trauma also shows temporal evolution with increase in extent of injury with time. Hence early CT scans may underestimate the extent of injures and sequential imaging with CT or MRI is important in pancreatic trauma. Sequential imaging is also needed for successful nonoperative management of pancreatic injury. Accurate early detection on initial CT and adopting a multimodality and sequential imaging strategy can improve outcome in pancreatic trauma. | Atin Kumar Ananya Panda Shivanand Gamanagatti | 2016 | World Journal of Radiology2016，8，2： | 8 |
| 5 | Imaging in renal trauma显示文摘Renal injuries are classified,based on the American Association for the Surgery of Trauma classification,in to five grades of injury.Several imaging modalities have been available for assessing the grade of renal injury,each with their usefulness and limitations.Currently,plain radiographs and intravenous urography have no role in the evaluation of patients with suspected renal injury.Ultrasonography(USG) has a limited role in evaluating patients with suspected retroperitoneal injury;however,it plays an important role during follow up in patients with urinoma formation.USG helps to monitor the size of a urinoma and also for the drainage procedure.The role of selective renal arteriography is mainly limited to an interventional purpose rather than for diagnostic utility.Retrograde pyelography is useful in assessing ureteral and renal pelvis integrity in suspected ureteropelvic junction injury and for an interventional purpose,like placing a stent across the site of ureteric injury.Magnetic resonance imaging has no role in acute renal injuries.Multidetector computed tomography is the modality of choice in the evaluation of renal injuries.It is also useful in evaluating traumatic injuries to kidneys with preexisting abnormalities and can help to define the extent of penetrating injuries in patients with stab wounds in the flank region.The combination of imaging findings along with clinical information is important in the management of the individual patient.This article will describe a spectrum of renal injuries encountered in a trauma setting. | Madhukar Dayal Shivanand Gamanagatti Atin Kumar | 2013 | World Journal of Radiology2013，5，8： | 6 |
| 6 | Clinicohistopathological implications of phosphoserine 9 glycogen synthase kinase-3β/β-catenin in urinary bladder cancer patients显示文摘BACKGROUND Aberrant activation of phosphorylated form of glycogen synthase kinase-3β[pS9 GSK-3β(Serine 9 phosphorylation)] is known to trigger Wnt/β-catenin signal cascade but its clinicohistopathological implications in bladder carcinogenesis remain unknown.AIM To investigate the diagnostic and prognostic relevance of expressions of pS9 GSK-3β, β-catenin and its target genes in the pathobiology of bladder cancer.METHODS Bladder tumor tissues from ninety patients were analyzed for quantitative expression and cellular localization of pS9 GSK-3β by immunohistochemical(IHC) staining. Real time-quantitative polymerase chain reaction and IHC were done to check the expression of β-catenin, Cyclin D1, Snail and Slug at transcriptome and protein level respectively. Clinicohistopathological variables were obtained from histology reports, follow up and OPD visits of patients.Expressions of the markers were statistically correlated with these variables to determine their significance in clinical setting. Results were analysed using SPSS20.0 software.RESULTS Aberrant(low or no membranous/high nuclear/high cytoplasmic) expression of pS9 GSK-3β was noted in 51% patients and found to be significantly associated with tumor stage and tumor grade(P = 0.01 and 0.04; Mann Whitney U test).Thirty one percent tumors exhibited aberrant co-expression of pS9 GSK-3β andβ–catenin proteins and showed strong statistical association with tumor stage,tumor type, smoking/tobacco chewing status(P = 0.01, 0.02 and 0.04, MannWhitney U test) and shorter overall survival probabilities of patients(P = 0.02;Kaplan Meier test). Nuclear immunostaining of Cyclin D1 in tumors with altered pS9 GSK-3β/β–catenin showed relevance with tumor stage, grade and type.CONCLUSIONβ–catenin and pS9 GSK-3β proteins are identified as markers of diagnostic/prognostic significance in disease pathogenesis. Observed histopathological association of Cyclin D1 identifies it as marker of potential relevance in tumors with altered pS9 GSK-3β/β-catenin. | Niharika Maurya Rinni Singh Apul Goel Atin Singhai Uday Pratap Singh Vinita Agrawal Minal Garg | 2019 | World Journal of Clinical Oncology2019，10，4： | 2 |
| 7 | Bilateral traumatic proximal humerus fractures managed by open reduction and internal fixation with locked plates显示文摘近似肱骨的破裂在年轻病人是不平常的。尽管近似肱骨本身的双边的骨折是稀罕的,有癫痫和电刑的协会是经常的。仅仅创伤的双边的近似肱骨骨折的一个案例在文学被报导了。我们在 40 岁男性病人报导双边的创伤的代替的近似肱骨破裂的一个稀罕案例,它与近似肱骨借助于开的减小和内部固定被对待在双方上锁了头并且获得了好功能的结果。 | Atin Jaiswal Naiman Deepak Kachchhapt Rupak Chaterjee Yashwant Singh Tanwar Masood Habib Satya Prakash Singh | 2013 | Chinese Journal of Traumatology2013，16，6： | 2 |
| 8 | First rib fractures: not always a hallmark of severe trauma a report of three cases显示文摘 | Atin Jaiswal Yashwant S Tanwar Masood Habib Vijay Jain | 2013 | Chinese Journal of Traumatology2013，16，4： | 2 |
| 9 | Blunt traumatic superior gluteal artery pseudoaneurysm presenting as gluteal hematoma without bony injury: A rare case report显示文摘 | Annu Babu Amit Gupta Pawan Sharma Piyush Ranjan Atin Kumar | 2016 | Chinese Journal of Traumatology2016，19，4： | 2 |
| 10 | Abernethy malformation with portal vein aneurysm显示文摘 | Atin K Jyoti K Rakesh A | 2008 | Diagn Interv Radiol2008，14，3： | 1 |
| 11 | Do N95 respirators provide 95% protection level against airborne viruses, and how adequate are surgical masks? 显示文摘 | Balazy Anna Toivola Mika Adhikari Atin | 2006 | Am J Infect Control2006，34，2： | 1 |
| 12 | Percutaneous elevation of depressed lunate fossa: A surgical technique显示文摘远侧的半径的死穿孔机破裂或装紧破裂关节的表面对对待并且努力困难完成令人满意的减小。我们在场提高沮丧的半月形的窝并且在这没有 grafting 的需要维持提高的碎片的减小的一种唯一、经皮、最低限度地侵略的技术断裂。这种技术简单,可再现并且能与简单乐器学被执行。我们认为它在远侧的半径破裂的处理值得许多含意。 | Atin Jaiswal Yashwant Singh Tanwar | 2018 | Chinese Journal of Traumatology2018，21，5： | 1 |
| 13 | Portal Hypertension Associated With Oxaliplatin Administration: Clinical Manifestations of Hepatic Sinusoidal Injury显示文摘 | Julian H. Slade Mona L. Alattar David R. Fogelman Michael J. Overman Atin Agarwal Dipen M. Maru Ryanne L. Coulson Chusilp Charnsangavej J. Nicolas Vauthey Robert A. Wolff Scott Kopetz | 2009 | Clinical Colorectal Cancer2009，，4： | 1 |
| 14 | Beta-endorphia in Acute Local Cerebral Infact显示文摘 | ATIN GN | 1989 | Med Clin Barc(S0025 - 7753)1989，93，7： | 1 |
| 15 | Chaotic analysis of the foreignexchange rates 显示文摘 | Atin D Pritha D | 2007 | Applied Mathematics andComputation2007，185，38： | 1 |
| 16 | Multicenter validation study of pathologic response and tumor thickness at the tumor‐normal liver interface as independent predictors of disease‐free survival after preoperative chemotherapy and surgery for colorectal liver metastases显示文摘 | Antoine Brouquet Giuseppe Zimmitti Scott Kopetz Judith Stift Catherine Julié Anne‐Isabelle Lemaistre Atin Agarwal Viren Patel Stephane Benoist Bernard Nordlinger Alessandro Gandini Michel Rivoire Stefan Stremitzer Thomas Gruenberger Jean‐Nicolas Vauthey D | 2013 | Cancer2013，，15： | 1 |
| 17 | Correlation of ambient inhalable bioaerosols with particulate matter and ozone: A two-year study显示文摘 | Atin Adhikari Tiina Reponen Sergey A. Grinshpun Dainius Martuzevicius Grace LeMasters | 2005 | Environmental Pollution2005，，1： | 1 |
| 18 | Durable Complete Responses in Metastatic Colorectal Cancer Treated with Chemotherapy Alone显示文摘 | Renata Ferrarotto Priyanka Pathak Dipen Maru Atin Agarwal Michael Overman Paulo M. Hoff Scott Kopetz | 2011 | Clinical Colorectal Cancer2011，，3： | 1 |
| 19 | Nonalcoholic fatty liver disease is associated with subclinical atherosclerosis independent of obesity and metabolic syndrome in Asian Indians显示文摘 | Manik Lal Thakur Sanjay Sharma Atin Kumar Surya Prakash Bhatt Kalpana Luthra Randeep Guleria Ravindra M. Pandey Naval K. Vikram | 2012 | Atherosclerosis2012，，2： | 1 |
| 20 | Mutational analysis of Ras hotspots in patients with urothelial carcinoma of the bladder显示文摘BACKGROUND Mutational activation of Ras genes is established as a prognostic factor for the genesis of a constitutively active RAS-mitogen activated protein kinase pathway that leads to cancer.Heterogeneity among the distribution of the most frequent mutations in Ras isoforms is reported in different patient populations with urothelial carcinoma of the bladder(UCB).AIM To determine the presence/absence of mutations in Ras isoforms in patients with UCB in order to predict disease outcome.METHODS This study was performed to determine the mutational spectrum at the hotspot regions of H-Ras,K-Ras and N-Ras genes by polymerase chain reaction-restriction fragment length polymorphism(PCR-RFLP)and DNA sequencing followed by their clinical impact(if any)by examining the relationship of mutational spectrum with clinical histopathological variables in 87 UCB patients.RESULTS None of the 87 UCB patients showed point mutations in codon 12 of H-Ras gene;codon 61 of N-Ras gene and codons 12,13 of K-Ras gene by PCR-RFLP.Direct DNA sequencing of tumor and normal control bladder mucosal specimens followed by Blastn alignment with the reference wild-type sequences failed to identify even one nucleotide difference in the coding exons 1 and 2 of H-Ras,NRas and K-Ras genes in the tumor and control bladder mucosal specimens.CONCLUSION Our findings on the lack of mutations in H-Ras,K-Ras and N-Ras genes could be explained on the basis of different etiological mechanisms involved in tumor development/progression,inherent genetic susceptibility,tissue specificity or alternative Ras dysfunction such as gene amplification and/or overexpression in a given cohort of patients. | Kiran Tripathi Apul Goel Atin Singhai Minal Garg | 2020 | World Journal of Clinical Oncology2020，11，8： | 1 |
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