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| 1 | Calcium sulfite oxidation in a slurry reactor 显示文摘 | WEISNICHT W l OVERMAN J WANG C C | 1980 | Chem Eng Sci1980，35，： | 3 |
| 2 | Stratification of outcomes for mucinous appendiceal adenocarcinoma with peritoneal metastasis by histological grade显示文摘AIM To investigate the importance of a three-tiered histologic grade on outcomes for patients with mucinous appendiceal adenocarcinoma(MAA).METHODS Two hundred and sixty-five patients with MAA undergoing cytoreductive surgery and hyperthermic intraperitoneal chemotherapy were identified from a prospective database from 2004 through 2014. All pathology was reviewed by our gastrointestinal subspecialty pathologists and histological grade was classified as well-differentiated, moderately differentiated, and poorly differentiated. Survival analysis was performed using Cox proportional hazards regression.RESULTS There were 201(75.8%) well-, 45(16.9%) moderatelyand 19(7.2%) poorly-differentiated tumors. Histological grade significantly stratified the 5-year overall survival(OS), 94%, 71% and 30% respectively(P < 0.001) as well as the 5-year disease-free survival(DFS) 66%, 21% and 0%, respectively(P < 0.001). Independent predictors of DFS included tumor grade(HR = 1.78, 95%CI: 1.21-2.63, P = 0.008), lymph node involvement(HR = 0.33, 95%CI: 0.11-0.98, P < 0.02), previous surgical score(HR = 1.31, 95%CI: 1.1-1.65, P = 0.03) and peritoneal carcinomatosis index(PCI)(HR = 1.05, 95%CI: 1.02-1.08, P = 0.002). Independent predictors of OS include tumor grade(HR = 2.79, 95%CI: 1.26-6.21, P = 0.01), PCI(HR = 1.10, 95%CI: 1.03-1.16, P = 0.002), and complete cytoreduction(HR = 0.32, 95%CI: 0.11-0.92, P = 0.03). Tumor grade and PCI were the only independent predictors of both DFS and OS. Furthermore, histological grade and lymphovascular invasion stratified the risk of lymph node metastasis into a low(6%) and high(40%) risk groups. CONCLUSION Our data demonstrates that moderately differentiated MAA have a clinical behavior and outcome that is distinct from well-and poorly-differentiated MAA. The threetier grade classification provides improved prognostic stratification and should be incorporated into patient selection and treatment algorithms. | Travis Edward Grotz Richard E Royal Paul F Mansfield Michael James Overman Gary N Mann Kristen Ashlee Robinson Karen A Beaty Safiea Rafeeq Auerlio Matamoros Michelle W Taggart Keith Francis Fournier | 2017 | World Journal of Gastrointestinal Oncology2017，9，9： | 2 |
| 3 | Model Analysis of Corn Response to Applied Nitrogen and Plant Population Density显示文摘 | Overman A R Schohz III R V Brock K H | 2006 | Communications in Soil Science and Plant Analysis2006，37，10： | 1 |
| 4 | Estimation of yield and nitrogen removal by corn显示文摘 | Overman A R Wilson D M Kampprath E J | 1994 | Agronomy Journal1994，86，： | 1 |
| 5 | Hydrolysis of pprosulfuron at pH5:evidence for a resonance-stablized triazine cleavage product显示文摘 | Bray L D Heard N E Overman M C | 1997 | Pestic Sci1997，51，： | 1 |
| 6 | Spatial evolution of the US ur- ban system显示文摘 | Ioannides Y M Overman H G | 2004 | Journal of economic geography2004，4，2： | 1 |
| 7 | Plastic ity in the injured brain: more than molecules matter显示文摘 | Overman J J Carmichael ST Thomas Carmichael | 2014 | Neuroscientist2014，20，1： | 1 |
| 8 | Use of research biopsies in clinical trials : Arc risks and benefits adequately discussed 显示文摘 | Overman M J Modak J Kopetz S | 2013 | J Clin Oncol2013，31，： | 1 |
| 9 | Contiguous stereogenlc quaternary carbons: A daunting challenge in natural products synthesis 显示文摘 | Peterson E A Overman L E | 2004 | Proc Natl Acad Sci USA2004，101，11： | 1 |
| 10 | Pallidotomy lesion locations:significance of microelectrode refinement显示文摘 | Tsao K Wilkinson S Overman J | 1998 | Neurosurgery1998，43，3： | 1 |
| 11 | Hydrolysis of prosulfuron at pH 5-Evidence for a resonance stabilized triazine cleavage product显示文摘 | Bray L D Heard N E Overman M C | 1997 | Pestic Sci1997，51，： | 1 |
| 12 | Acute infective endo- carditis caused by Delftia acidovorans, a rare pathogen complicating intravenous drug use 显示文摘 | Mahmood S Taylor KE Overman TL | 2012 | J Clin Microbiol2012，50，11： | 1 |
| 13 | Improved survival in metastatic colorectal cancer is associated with adoption of hepatic resection and improved chemotherapy显示文摘 | Kopetz S Chang GJ Overman MJ | 2009 | J Clin Oncol2009，27，： | 1 |
| 14 | Doxorubicin-resistant variants ofhuman prostate cancer cell lines DU 145,PC-3,PPC-1,and TSU-PR1:characterization ofbiochemical determinants of antineoplastic drug sensitivity显示文摘 | David-Beabes GL Overman MJ Petrofski JA | 2000 | Int JOncol2000，17，： | 1 |
| 15 | Microeneapsulated Phase Change Materials as Heat Transfer Media in Gas-fluidized Beds 显示文摘 | Brown R C Rasderry J D Overman S P | 1998 | Power Technology1998，98，3： | 1 |
| 16 | An age-related sprouting transcriptome provides molecular control of axonal sprouting after stroke 显示文摘 | Li S Overman J J Katsman D | 2010 | Nat Neurosci2010，13，12： | 1 |
| 17 | Microsporidiosis myositis in a patient with the acquired immunedeficiency syndrome显示文摘 | Ledford DK Overman MD Gonzalvo A | 1985 | Ann Intern Med1985，102，5： | 1 |
| 18 | Goblet cell carcinoid tumor, mixed goblet cell ca~inoid-adenoca~inoma, amt adenoeareinoma of the appendix: comparison of clinicopathologic features and prognosis 显示文摘 | TAGGART MW ABRAHAM SC OVERMAN MJ | 2015 | Areh Pathol Lab Med2015，139，6： | 1 |
| 19 | Improved survival in metastatic colorectal cancer is associated with adoption of he- patic resection and improved chemotherapy 显示文摘 | Kopetz S Chang GJ Overman MJ | 2009 | J Clin Oncol2009，27，22： | 1 |
| 20 | Immunophenotype and mo-lecular characterisation of adenocarcinoma of the small intestine 显示文摘 | Overman MJ Pozadzides J Kopetz S | 2010 | BrJ Cancer2010，102，1： | 1 |
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