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| 1 | Preoperative biliary drainage in patients with hilar cholangiocarcinoma undergoing major hepatectomy显示文摘AIM:To investigate the effect of preoperative biliary drainage(PBD)in jaundiced patients with hilar cholangiocarcinoma(HCCA)undergoing major liver resections.METHODS:An observational study was carried out by reviewing a prospectively maintained database of HCCA patients who underwent major liver resection for curative therapy from January 2002 to December 2012.Patients were divided into two groups based on whether PBD was performed:a drained group and an undrained group.Patient baseline characteristics,preoperative factors,perioperative and short-term postoperative outcomes were compared between the two groups.Risk factors for postoperative complications were also analyzed by logistic regression test with calculating OR and 95%CI.RESULTS:In total,78 jaundiced patients with HCCA underwent major liver resection:32 had PBD prior to operation while 46 did not have PBD.The two groups were comparable with respect to age,sex,body mass index and co-morbidities.Furthermore,there was no significant difference in the total bilirubin(TBIL)levels between the drained group and the undrained group at admission(294.2±135.7 vs 254.0±63.5,P=0.126).PBD significantly improved liver function,reducing not only the bilirubin levels but also other liver enzymes.The preoperative TBIL level was significantly lower in the drained group as compared to the undrained group(108.1±60.6 vs 265.7±69.1,P=0.000).The rate of overall postoperative complications(53.1%vs 58.7%,P=0.626),reoperation rate(6.3%vs 6.5%,P=1.000),postoperative hospital stay(16.5 vs 15.0,P=0.221)and mortality(9.4%vs 4.3%,P=0.673)were similar between the two groups.In addition,there was no significant difference in infectious complications(40.6%vs 23.9%,P=0.116)and noninfectious complications(31.3%vs 47.8%,P=0.143)between the two groups.Univariate and multivariate analyses revealed that preoperative TBIL>170μmol/L(OR=13.690,95%CI:1.275-147.028,P=0.031),Bismuth-Corlette classification(OR=0.013,95%CI:0.001-0.166,P=0.001)and extended liver resection(OR=14.010,95%CI:1.130-173.646,P=0.040)were independent risk factors for postoperative complications.CONCLUSION:Overall postoperative morbidity and mortality rates after major liver resection are not improved by PBD in HCCA patients with jaundice.Preoperative TBIL>170μmol/L,Bismuth-Corlette classification and extended liver resection are independent risk factors linked to postoperative complications. | Jun-Jie Xiong Quentin M Nunes Wei Huang Samir Pathak Ai-Lin Wei Chun-Lu Tan Xu-Bao Liu | 2013 | World Journal of Gastroenterology2013，19，46： | 33 |
| 2 | Multi-objective optimization of oil well drilling using elitist non-dominated sorting genetic algorithm显示文摘A multi-objective optimization of oil well drilling has been carried out using a binary coded elitist non-dominated sorting genetic algorithm. A Louisiana offshore field with abnormal formation pressure is considered for optimization. Several multi-objective optimization problems involving two-and three-objective functions were formulated and solved to fix optimal drilling variables. The important objectives are:(i) maximizing drilling depth,(ii) minimizing drilling time and(iii) minimizing drilling cost with fractional drill bit tooth wear as a constraint. Important time dependent decision variables are:(i) equivalent circulation mud density,(ii) drill bit rotation,(iii) weight on bit and(iv) Reynolds number function of circulating mud through drill bit nozzles. A set of non-dominated optimal Pareto frontier is obtained for the two-objective optimization problem whereas a non-dominated optimal Pareto surface is obtained for the three-objective optimization problem. Depending on the trade-offs involved, decision makers may select any point from the optimal Pareto frontier or optimal Pareto surface and hence corresponding values of the decision variables that may be selected for optimal drilling operation. For minimizing drilling time and drilling cost, the optimum values of the decision variables are needed to be kept at the higher values whereas the optimum values of decision variables are at the lower values for the maximization of drilling depth. | Chandan Guria Kiran K Goli Akhilendra K Pathak | 2014 | Petroleum Science2014，11，1： | 10 |
| 3 | Size Distributions of Aerosol Sulfates and Nitrates in Beijing during the 2008 Olympic Games: Impacts of Pollution Control Measures and Regional Transport显示文摘为 2008 个奥运会,激烈的控制措施在二氧化物(SO2 ) ,氮氧化物(没有 x ) 和处理穷人的问题的另外的污染物质通风的硫的工业、城市的排出物上被实现在北京的质量。在微粒硫酸盐和硝酸盐集中以及他们的尺寸分布上调查 SO2 和没有 x 减小的效果,分离尺寸的喷雾器样品在照原尺寸的控制前后在北京在城市、顺风的农村地点用微孔的一致存款 impactors (MOUDI ) 被收集。在采样时期期间,在城市、农村的地点的好粒子(PM1.8 ) 的集体集中分别地是 94.0 和 85.9 g m3。超过 90% 硫酸盐和 60% 硝酸盐形成了同样好的粒子。得益于有益的气象学的条件和来源控制,硫酸盐在奥林匹克期间在相当低的集中并且首先在冷凝作用模式被观察。控制措施的效果独立被分析让北风和南方的 air-mass-dominated 天说明任何偏爱。在控制措施被实现以后,当在北方的空气群众占优势时,下午,硫酸盐,和硝酸盐显著地被减少,与在更大的粒子的减小的一个更高的百分比。在控制措施被实现以后,微滴模式粒子,在控制被实现以前,统治了硫酸盐和硝酸盐,显著地在集体集中被减少。但当弄脏的南方的空气群众占优势时,本地来源控制在北京测量,有效地没从北方中国平原由于庞大的地区性的贡献减少周围的硫酸盐集中。 | WANG Xinfeng WANG Tao Ravi Kant PATHAK Mattias HALLQUIST GAO Xiaomeit NIE Wei XUE Likun GAO Jian GAO Rui ZHANG Qingzhu WANG Wenxing WANG Shulan CHAI Fahe CHEN Yizhen | 2013 | Advances in Atmospheric Sciences2013，30，2： | 8 |
| 4 | Photochemical smog in China:scientific challenges and implications for air-quality policies显示文摘INTRODUCTION Severe air-pollution events in many parts of China pose a major threat to health and ecosystems[1].China’s air pollution is concentrated to economically developed areas,such as Beijing–Tianjin–Hebei(BTH)and Pearl–River–Delta(PRD)[2,3].The situation has received considerable attention in | Mattias Hallquist John Munthe Min Hu Tao Wang Chak K Chan Jian Gao Johan Boman Song Guo Asa M Hallquist Johan Mellqvist Jana Moldanova Ravi K Pathak Jan BC Pettersson Hakan Pleijel David Simpson Marie Thynell | 2016 | National Science Review2016，3，4： | 8 |
| 5 | Autoheated thermophilic aerobic sludge digestion and metal bioleaching in a two-stage reactor system显示文摘A two-stage process has been developed for stabilization of sludge and removal of heavy metals from the secondary activated sludge with high rate of energy and time conservation.The first stage of the process involves autoheated thermophilic aerobic digestion at 55-60°C inoculated with less-acidophilic thermophilic sulfur-oxidizing microorganisms(ATAD).The results show that it is possible to maintain the autoheated conditions(55-60°C) in the ATAD reactor up to 24 hr,leading to reduction of 21% total solids(TS),27% volatile solids(VS),27% suspended solids(SS) and 33% volatile suspended solids(VSS) from the sludge.The sludge pH also decreased from 7 to 4.6 due to the activity of less-acidophilic thermophilic microorganisms.In the second stage operation,the digested sludge(pH 4.6,TS 31.6 g/L) from stage one was subjected to bioleaching in a continuous stirred tank reactor,operated at mean hydraulic retention times(HRTs) of 12,24 and 36 hr at 30°C.An HRT of 24 hr was found to be sufficient for removal of 70% Cu,70% Mn,75% Ni,and 80% Zn from the sludge.In all,39% VSS,76% Cu,78.2% Mn,79.5% Ni and 84.2% Zn were removed from the sludge in both the stages. | Rohan Jain Ashish Pathak T.R.Sreekrishnan M.G.Dastidar | 2010 | Journal of Environmental Sciences2010，22，2： | 7 |
| 6 | Silicon and silicon nitride photonic circuits for spectroscopic sensing on-a-chip [Invited]显示文摘There is a rapidly growing demand to use silicon and silicon nitride(Si3N4) integrated photonics for sensing applications, ranging from refractive index to spectroscopic sensing. By making use of advanced CMOS technology,complex miniaturized circuits can be easily realized on a large scale and at a low cost covering visible to mid-IR wavelengths. In this paper we present our recent work on the development of silicon and Si3N4-based photonic integrated circuits for various spectroscopic sensing applications. We report our findings on waveguide-based absorption, and Raman and surface enhanced Raman spectroscopy. Finally we report on-chip spectrometers and on-chip broadband light sources covering very near-IR to mid-IR wavelengths to realize fully integrated spectroscopic systems on a chip. | Ananth Z.Subramanian Eva Ryckeboer Ashim Dhakal Frédéric Peyskens Aditya Malik Bart Kuyken Haolan Zhao Shibnath Pathak Alfonso Ruocco Andreas De Groote Pieter Wuytens Daan Martens Francois Leo Weiqiang Xie Utsav Deepak Dave Muhammad Muneeb Pol Van Dorpe Joris Van Campenhout Wim Bogaerts Peter Bienstman Nicolas Le Thomas Dries Van Thourhout Zeger Hens Gunther Roelkens Roel Baets | 2015 | Photonics Research2015，3，5： | 7 |
| 7 | Human sperm immobilization effect of Carica papaya seed extracts: an in vitro study显示文摘Aim: To examine if the seed extracts of Carica papaya, which showed antispermatogenic/sperm immobilization properties in animal models, could cause human sperm immobilization in vitro. Methods: Chloroform extract, benzene chromatographic fraction of the chloroform extract, its methanol and ethyl acetate sub-fractions and the isolated compounds from the sub-fractions i.e., ECP 1 & 2 and MCP 1 & 2, of the seeds of Cadca papaya were used at concentrations of 0.1%, 0.5%, 1% and 2%. Sperm motility was assessed immediately after addition of extracts and every 5 minutes thereafter for 30 minutes. Results: There were dose-dependent spermicidal effects showing an instant fall in the sperm motility to less than 20 % at 2 % concentration. Isolated compounds ECP 1 & 2 were more effective inducing a motility of less than 10%. Many of the spermatozoa became vibratory on the spot. Total inhibition of motility was observed within 20 - 25 min at all concentrations of all products. Scanning and transmission electron microscopy revealed deleterious changes in the plasma membrane of the head and mid-piece of spermatozoa. Sperm viability test and the number of abnormal spermatozoa after completion of incubation suggested that the spermatozoa were infertile. The effects were spermicidal but not spermiostatic as revealed by the sperm revival test. Conclusion: The results reveal spermicidal activity in vitro of the seed extracts of Carica papaya. | Nirmal K Lohiya Lalit K Kothari B Manivannan Pradyumna K Mishra Neelam Pathak | 2000 | Asian Journal of Andrology2000，2，2： | 6 |
| 8 | Varicocele management in the era of in vitro fertilization/intracytoplasmic sperm injection显示文摘精索静脉曲张是男不孕的最普通的通过手术可对待的原因,并且经常在精液参数,精子 DNA 损坏,和精液的周围的变化导致改变。精索静脉曲张修理能与临床的精索静脉曲张在人的多数在这些参数导致改进;与无临床症状的精索静脉曲张在人支持修理的数据是不太权威的。在用帮助繁殖技术(艺术)寻求富饶的夫妇,精索静脉曲张修理可以在能用技术例如增加成功的授精的可能性的精液参数和精子健康提供改进在 vitro 授精( IVF )或 intracytoplasmic 精子注射( ICSI ),或可以减少艺术的水平需要完成成功的怀孕。男不孕是有向健康能便于最佳的屏蔽和这些人的治疗的未来的一只眼睛的不肥沃的男性的一般男健康,和评估的指示物。而且,精索静脉曲张可以代表进步损害,提供为它的修理的争论,尽管这当前是不清楚的。 | Piyush Pathak Aravind Chandrashekar Tariq S Hakky Alexander W Pastuszak | 2016 | Asian Journal of Andrology2016，18，3： | 5 |
| 9 | AN INVESTIGATION OF TURBULENT RECTANGULAR JET DISCHARGED INTO A NARROW CHANNEL WEAK CROSSFLOW显示文摘A computational investigation of the mean flow field of turbulent rectangular jets issuing into a narrow channel crossflow is presented. The length of the jet slot spans more than 55% of the crossflow channel bed, leaving a small clearance between the jet edge and sidewalls. A finite volume code employing the standard k-ε model is used to predict the mean, three-dimensional flow field. The mean flow field is investigated for two velocity ratios (6 and 9). Important flow features, such as the formation of different vortical structures and their characteristics owing to different values of the velocity ratio, are discussed. Some predicted results are compared with the experimental data reported in the literature. The predicted mean and turbulent flow properties are shown to be in good agreement with the experimental data. | PATHAK Manabendra DASS Anoop K. DEWAN Anupam | 2008 | Journal of Hydrodynamics2008，20，2： | 5 |
| 10 | Role of mucoadhesive polymers in enhancing delivery of nimodipine microemulsion to brain via intranasal route显示文摘Intranasal drug administration is receiving increased attention as a delivery method for by-passing the blood–brain barrier and rapidly targeting therapeutics to the CNS.However,rapid mucociliary clearance in the nasal cavity is a major hurdle.The purpose of this study was to evaluate the effect of mucoadhesive polymers in enhancing the delivery of nimodipine microemulsion to the brain via the intranasal route.The optimized mucoadhesive microemulsion was characterized,and the in vitro drug release and in vivo nasal absorption of drug from the new formulation were evaluated in rats.The optimized formulation consisted of Capmul MCM as oil,Labrasol as surfactant,and Transcutol P as co-surfactant,with a particle size of 250 nm and zeta potential value of?15 mV.In vitro and ex vivo permeation studies showed an initial burst of drug release at 30 min and sustained release up to 6 h,attributable to the presence of free drug entrapped in the mucoadhesive layer.In vivo pharmacokinetic studies in rats showed that the use of the mucoadhesive microemulsion enhanced brain and plasma concentrations of nimodipine.These results suggest that incorporation of a mucoadhesive agent in a microemulsion intranasal delivery system can increase the retention time of the formulation and enhance brain delivery of drugs. | Rudree Pathak Ranjeet Prasad Dash Manju Misr Manish Nivsarkar | 2014 | Acta Pharmaceutica Sinica B2014，4，2： | 5 |
| 11 | 5-ASA colonic mucosal concentrations resulting from different pharmaceutical formulations in ulcerative colitis显示文摘AIM:To compare the mucosal concentrations of 5-aminosalicylic acid(5-ASA)resulting from different pharmaceutical formulations and analyse the influence of inflammation on the mucosal concentrations.METHODS:The study included 130 inflammatory bowel disease(IBD)patients receiving 5-ASA as pH-dependent-release formulations(73 patients),time-dependent-release formulations(11 patients),or pro-drugs(18patients).In addition,28 patients were receiving topical treatment(2-4 g/d)with pH-dependent-release formulations.Endoscopic biopsies were obtained from the sigmoid region during the colonoscopy.The 5-ASA concentrations(ng/mg)were measured in tissue homogenatesusing high-pressure liquid chromatography with electrochemical detection.The t test and Mann-Whitney test,when appropriate,were used for statistical analysis.RESULTS:Patients receiving pH-dependent-release formulations showed significantly higher mucosal concentrations of 5-ASA(51.75±5.72 ng/mg)compared with patients receiving pro-drugs(33.35±5.78 ng/mg,P=0.01)or time-dependent-release formulations(38.24±5.53 ng/mg,P=0.04).Patients with endoscopic remission had significantly higher mucosal concentrations of5-ASA than patients with active disease(60.14±7.95ng/mg vs 35.66±5.68 ng/mg,P=0.02).Similar results were obtained when we compared patients with the histological appearance of remission and patients with active histological inflammation(67.53±9.22 ng/mg vs 35.53±5.63 ng/mg,P<0.001).Significantly higher mucosal concentrations of 5-ASA were detected in patients treated with both oral and topical treatments in combination compared with patients who received oral treatment with pH-dependent-release formulations alone(72.33±11.23 ng/mg vs 51.75±5.72 ng/mg,P=0.03).CONCLUSION:IBD patients showed significant variability in mucosal 5-ASA concentrations depending on the type of formulation,and the highest mean concentration was achieved using pH-dependent-release formulations. | Renata D’Incà Martina Paccagnella Romilda Cardin Surajit Pathak Vincenzo Baldo Maria Cecilia Giron Giacomo Carlo Sturniolo | 2013 | World Journal of Gastroenterology2013，19，34： | 4 |
| 12 | Tailored PEDOT:PSS hole transport layer for higher performance in perovskite solar cells: Enhancement of electrical and optical properties with improved morphology显示文摘Precise control over the charge carrier dynamics throughout the device can result in outstanding performance of perovskite solar cells(PSCs).Poly(3,4-ethylenedioxythiophene):poly(styrene sulfonate)(PEDOT:PSS)is the most actively studied hole transport material in p-i-n structured PSCs.However,charge transport in the PEDOT:PSS is limited and inefficient because of its low conductivity with the presence of the weak ionic conductor PSS.In addition,morphology of the underlying PEDOT:PSS layer in PSCs plays a crucial role in determining the optoelectronic quality of the active perovskite absorber layer.This work is focused on realization of a non-wetting conductive surface of hole transport layer suitable for the growth of larger perovskite crystalline domains.This is accomplished by employing a facile solventengineered(ethylene glycol and methanol)approach resulting in removal of the predominant PSS in PEDOT:PSS.The consequence of acquiring larger perovskite crystalline domains was observed in the charge carrier dynamics studies,with the achievement of higher charge carrier lifetime,lower charge transport time and lower transfer impedance in the solvent-engineered PEDOT:PSS-based PSCs.Use of this solventengineered treatment for the fabrication of MAPbI3 PSCs greatly increased the device stability witnessing a power conversion efficiency of 18.18%,which corresponds to^37%improvement compared to the untreated PEDOT:PSS based devices. | Khan Mamun Reza Ashim Gurung Behzad Bahrami Sally Mabrouk Hytham Elbohy Rajesh Pathak Ke Chen Ashraful Haider Chowdhury Md Tawabur Rahman Steven Letourneau Hao-Cheng Yang Gopalan Saianand Jeffrey WElam Seth BDarling Qiquan Qiao | 2020 | Journal of Energy Chemistry2020，29，5： | 4 |
| 13 | Application of artificial intelligence to forecast hydrocarbon production from shales显示文摘Artificial intelligence(AI)methods and applications have recently gained a great deal of attention in many areas,including fields of mathematics,neuroscience,economics,engineering,linguistics,gaming,and many others.This is due to the surge of innovative and sophisticated AI techniques applications to highly complex problems as well as the powerful new developments in high speed computing.Various applications of AI in everyday life include machine learning,pattern recognition,robotics,data processing and analysis,etc.The oil and gas industry is not behind either,in fact,AI techniques have recently been applied to estimate PVT properties,optimize production,predict recoverable hydrocarbons,optimize well placement using pattern recognition,optimize hydraulic fracture design,and to aid in reservoir characterization efforts.In this study,three different AI models are trained and used to forecast hydrocarbon production from hydraulically fractured wells.Two vastly used artificial intelligence methods,namely the Least Square Support Vector Machine(LSSVM)and the Artificial Neural Networks(ANN),are compared to a traditional curve fitting method known as Response Surface Model(RSM)using second order polynomial equations to determine production from shales.The objective of this work is to further explore the potential of AI in the oil and gas industry.Eight parameters are considered as input factors to build the model:reservoir permeability,initial dissolved gas-oil ratio,rock compressibility,gas relative permeability,slope of gas oil ratio,initial reservoir pressure,flowing bottom hole pressure,and hydraulic fracture spacing.The range of values used for these parameters resemble real field scenarios from prolific shale plays such as the Eagle Ford,Bakken,and the Niobrara in the United States.Production data consists of oil recovery factor and produced gas-oil ratio(GOR)generated from a generic hydraulically fractured reservoir model using a commercial simulator.The Box-Behnken experiment design was used to minimize the number of simulations for this study.Five time-based models(for production periods of 90 days,1 year,5 years,10 years,and 15 years)and one rate-based model(when oil rate drops to 5 bbl/day/fracture)were considered.Particle Swarm Optimization(PSO)routine is used in all three surrogate models to obtain the associated model parameters.Models were trained using 80%of all data generated through simulation while 20%was used for testing of the models.All models were evaluated by measuring the goodness of fit through the coefficient of determination(R2)and the Normalized Root Mean Square Error(NRMSE).Results show that RSM and LSSVM have very accurate oil recovery forecasting capabilities while LSSVM shows the best performance for complex GOR behavior.Furthermore,all surrogate models are shown to serve as reliable proxy reservoir models useful for fast fluid recovery forecasts and sensitivity analyses. | Palash Panja Raul Velasco Manas Pathak Milind Deo | 2018 | Petroleum2018，4，1： | 4 |
| 14 | Growth inhibition mediated by PSP94 or CRISP-3 is prostate cancer cell line specific显示文摘94 氨基酸(PSP94 ) 的能分泌的蛋白质被显示出与充满半胱氨酸的能分泌的蛋白质交往的前列腺 3 (CRISP-3 ) 在里面人的精液的血浆。有趣地, PSP94 表示被减少或在前列腺瘤的多数输了,而 CRISP-3 表示与正常前列腺织物相比是在前列腺癌症的 upregulated。为了获得单个角色的更好的理解,这些蛋白质在前列腺 tumourigenesis 和他们的相互作用的功能的关联有,我们宫外地在三根前列腺细胞线(PC3, WPE1-NB26 和 LNCaP ) 与 CRISP-3 一起表示了 PSP94 或 PSP94 并且执行了生长抑制试金。反向的抄写聚合酶链反应和西方的污点分析被用来为 PSP94 和 CRISP-3 表示屏蔽前列腺房间线。为人的 PSP94 和 CRISP-3 的哺乳动物的表示构造也被产生, recombinant 蛋白质的表示,本地化和分泌物是由西方的污点分析和 immunofluorescence 试金跟随的 transfection 的 assayed。PSP94 或 CRISP-3 的宫外的表示在房间生长上有的效果被 clonogenic 幸存试金追随者 transfection 学习。评估二蛋白质的合作表示的效果,表示了 PSP94 的 PC3 的稳定的克隆被产生。他们是随后有 CRISP-3 表示构造的 transfected 并且使遭到了到 clonogenic 幸存试金。我们的结果证明 PSP94 和 CRISP-3 能各在一根细胞线导致生长抑制特定的举止。尽管 CRISP-3-positive 房间线的生长被 PSP94 禁止,生长抑制由 CRISP-3 调停了没被 PSP94 的存在或缺席影响。这建议 CRISP-3 可以在前列腺 tumourigenesis 期间参予 PSP94 独立的活动。 | Bhakti R. Pathak Ananya A. Breed Vaishali H. Nakhawa Dhanashree D. Jagtap Smita D. Mahale | 2010 | Asian Journal of Andrology2010，12，5： | 3 |
| 15 | A rare presentation of cystic nephroma in a young adult显示文摘Cystic nephroma is a rare benign renal lesion with non-specific presenting symptoms.This tumour has a bimodal age distribution presenting in children between 3 months and 2 years and in adults over 30 years of age.There is male preponderance with a 2:1 male to female ratio in the childhood whereas it is commoner in females in adults.It is uncommon in the age-group of 5 yearse30 years.We describe a case of cystic nephroma in a 25-year-old female which was managed by partial nephrectomy. | Amit Sharma Mukund Andankar Hemant Pathak | 2017 | Asian Journal of Urology2017，4，2： | 3 |
| 16 | 宫颈粒细胞肉瘤显示文摘Background. Granulocytic sarcoma of the cervix, leading to the diagnosis of acute myelogenous leukemia (AML), is a rare event. Case. A 33- year- old woman presented with vaginal bleeding, pain, and a large pelvic mass involving the cervix, extending bilaterally to the pelvic side walls. A biopsy of the cervix revealed granulocytic sarcoma, and a subsequent bone marrow biopsy confirmed the diagnosis of AML. Results. The majority of patients with cervical granulocytic sarcoma present with vaginal bleeding, sometimes with abdominal pain and other systemic symptoms. The overall 2- year survival rates for all patients with granulocytic sarcoma in the literature is 6% , and none of the patients lived 5 years. Conclusion. Granulocytic sarcoma of the cervix is rare. Awareness of this entity will allow earlier diagnosis and appropriate treatment. | Pathak B. Bruchim I. Brisson M.- L. W.H. Gotlieb 杨晓梅 | 2006 | 世界核心医学期刊文摘(妇产科学分册)2006，2，1： | 3 |
| 17 | Eu(Ⅲ) Indirect Probe to Investigate Interaction of DOPA (3,4,Di-Hydroxyphenylalanine) and Dopamine (3,4-Dihydroxy Phenyl Ethyl Amine) Using Electrochemical Methods显示文摘Eu(Ⅲ) can be utilized as an indirect electrochemical probe to investigate the interaction of bio-molecules such as DOPA and Dopamine with Ca(Ⅱ) in vitro. The interaction of DOPA and Dopamine with Eu(Ⅲ)-Eu(Ⅱ) redox pair was investigated by electrochemical techniques. Both the neurotransmitters are structurally related and undergo interaction with Eu(Ⅲ). Eu(Ⅲ) coordinates with DOPA and Dopamine through five-member chelate rings via carboxylic oxygen and amino nitrogen. The electrode kinetic parameters viz, transfer coefficient (α_ na ), diffusion coefficient (D), forward heterogeneous rate constant (k^0_ fh ) were evaluated for Eu(Ⅲ)-DOPA/Eu(Ⅲ)-Dopamine. The results obtained were used to investigate the nature of interaction of Eu(Ⅲ) with multi-donor biomolecules. The possible mechanism was also proposed. [BT(4+1] | Prashant N Bhatt Trupti V Pathak Jignasu P Mehta G.Ramchandraiha | 2006 | Journal of Rare Earths2006，24，6： | 3 |
| 18 | Do we really need to repair the pronator quadratus after distal radius plating?显示文摘Purpose:Fractures of distal radius are one of the common orthopaedic injuries.Placing the plate on volar surface requires release of underlying pronator quadratus(PQ)muscle.No consensus is present in the literature about the repair or not of the PQ.The purpose of this study was to evaluate the influence of PQ repair on functional outcome and complications.Methods:Retrospectively 83 patients of distal radius fractures managed with volar plating between 2014 and 2016 were evaluated.Demographic data,operative notes and physical therapy records were retrieved.Patients were divided into group A where PQ repair was done and group B where no repair was done.Functional data such as range of motion(ROM),grip strength,visual analogue scale(VAS)score and disabilities of arm,shoulder and hand(DASH)score at 4 weeks,3 months,6 months and finial follow-up were retrieved.Results:Totally 63 patients(n=29 in group A and n=34 in group B)with the mean age of 51.64 years were examined.Patients were followed up for a mean of 35.2 months(range 27.2-47.1 months)in group A and 38.6 months(range 28.6-51.0 months)in group B.Though functional outcome of the affected limb was not significantly different between two groups after 3 months,PQ repair did affect the recovery at an early stage.Repair group had significantly better ROM(p=0.0383)and VAS score at 4 weeks(p=0.017)while grip strength(p=0.014)was significantly better at 3 months.Conclusions:Repair of PQ may provide pain relief and increased ROM in early postoperative period and hence every attempt should be made to achieve the repair. | Subodh Pathak Rashid Anjum Rakesh Kumar Gautam Pritam Maheshwari Jatin Aggarwal Aryan Sharma Vineet Pruthi | 2019 | Chinese Journal of Traumatology2019，22，6： | 3 |
| 19 | Renewable energy resources, policies and gaps in BRICS countries and the global impact显示文摘This paper presents comparative yet extensive analysis of existing non-conventional renewable resources, energy policies and gaps in BRICS countries. An intelligent transformation to green economy to maintain natural resources is noted. Brazil has stable energy policies and is the leading producer of biofuels following hydropower until 2014 but supported wind and solar power development by tendering specific tariffs for energy generation from solar and wind. Russia needs improvement in its legal and regulatory framework with more incentives in energy policies. China is improving upon wind and hydropower but it needs strong policy measures to put cap on increased CO2 emissions. India needs revision in energy policy and requires extra incentives and consumer specific energy policies for research-infrastructure and energy generation technologies. South Africa requires lessons to increase renewable energy and reduce coal mining. Moreover, BRICS countries need to redefine their energy policies based upon their existing geographical, economical, societal and environmental conditions which will help in shaping global energy policies and more financial stability. This paper recognizes the potential of BRICS to reshape the global system paralleled with minimizing CO2 emissions. The concerted role of BRICS needs to be recognized as the leading contributor of global renewable capacity where the developed world is geared and busy to address the environmental issues. | Lakshmi PATHAK Kavita SHAH | 2019 | Frontiers in Energy2019，13，3： | 2 |
| 20 | Some studies on the impact behavior of banded microalloyed steel显示文摘 | P. Shanmugam S.D. Pathak | 1996 | Engineering Fracture Mechanics1996，，6： | 2 |
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