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10篇 您的检索式:作者名="Andrew Godwin"
    题名 作者 年代 出处 被引量
1破产重整程序中的管理人制度显示文摘中国企业重整程序中的管理人制度尚存有诸多需要用立法或司法解释作出进一步改进的地方。这里主要包括两个大问题,首先是管理人的选任方法、任职资格以及报酬等有关管理人的选任程序相关的问题;其次是管理人的权限、义务等涉及管理人就任后的职责履行方面的规制问题。金春 Stacey Steele Andrew Godwin 2010政法论坛2010,28,6:8
2Loss of A-type lamin expression compromises nuclear envelope integrity in breast cancer显示文摘Through advances in technology,the genetic basis of cancer has been investigated at the genomic level,and many fundamental questions have begun to be addressed.Among several key unresolved questions in cancer biology,the molecular basis for the link between nuclear deformation and malignancy has not been determined.Another hallmark of human cancer is aneuploidy;however,the causes and consequences of aneuploidy are unanswered and are hotly contested topics.We found that nuclear lamina proteins lamin A/C are absent in a significant fraction(38%) of human breast cancer tissues.Even in lamin A/C-positive breast cancer,lamin A/C expression is heterogeneous or aberrant(such as non-nuclear distribution) in the population of tumor cells,as determined by immunohistology and immunofluorescence microscopy.In most breast cancer cell lines,a significant fraction of the lamin A/C-negative population was observed.To determine the consequences of the loss of lamin A/C,we suppressed their expression by shRNA in noncancerous primary breast epithelial cells.Down-regulation of lamin A/C in breast epithelial cells led to morphological deformation,resembling that of cancer cells,as observed by immunofluorescence microscopy.The lamin A/C-suppressed breast epithelial cells developed aneuploidy as determined by both flow cytometry and fluorescence in situ hybridization.We conclude that the loss of nuclear envelope structural proteins lamin A/C in breast cancer underlies the two hallmarks of cancer aberrations in nuclear morphology and aneuploidy.Callinice D. Capo-chichi Kathy Q. Cai Jennifer Smedberg Parvin Ganjei-Azar Andrew K. Godwin Xiang-Xi Xu 2011Chinese Journal of Cancer2011,30,6:2
3Mixing line isochrones:A new interpretation of galena lead isotope data from southeastern British Columbia显示文摘Andrew A Godwin C I Sinclair A J 1984Economic Geology1984,79,:1
4Regulation of miR-200 family microRNAs and ZEB transcription factors in ovarian cancer: Evidence supporting a mesothelial-to-epithelial transition显示文摘Ausra Bendoraite Emily C. Knouf Kavita S. Garg Rachael K. Parkin Evan M. Kroh Kathy C. O’Briant Aviva P. Ventura Andrew K. Godwin Beth Y. Karlan Charles W. Drescher Nicole Urban Beatrice S. Knudsen Muneesh Tewari 2009Gynecologic Oncology2009,,1:1
5VERNAUZATION1 Modulates Root System Architecture in Wheat and Barley显示文摘Kai P. Voss-Fels Hannah Robinson Stephen R. Mudge Cecile Richard Saul Newman Benjamin Wittkop Andreas Stahl Wolfgang Friedt Matthias Frisch lulian Gabur Anika Miller-Cooper Bradley C. Campbell Alison Kelly Glen Fox Jack Christopher Mandy Christopher Karine Chenu Jerome Franckowiak Emma S. Mace Andrew K. Borrell Howard Eagles David R. Jordan Jose R. Botella Graeme Hammer lan D. Godwin Ben Trevaskis Rod J. Snowdon Lee T. Hickey 2018Molecular Plant2018,11,1:1
6MicroRNA-34b and MicroRNA-34c Are Targets of p53 and Cooperate in Control of Cell Proliferation and Adhesion-Independent Growth显示文摘David C Corney Andrea Flesken-Nikitin Andrew K Godwin 2007Cancer Res2007,67,18:1
7Mixing line isochrons: a new interception of' galena lead isotope data from southea- stem British Columbia显示文摘Andrew A Godwin C I Sinclair AJ 1984Economic Geology1984,79,:1
8Mixing line isochrones: A new interpretation of galena lead isotope data from southeastern British Columbia 显示文摘Andrew A Godwin C I Sinclair A J 1984Economic Geology1984,79,:1
9Phase II trial of single agent cetuximab in patients with persistent or recurrent epithelial ovarian or primary peritoneal carcinoma with the potential for dose escalation to rash显示文摘Russell J. Schilder Harsh B. Pathak Anna E. Lokshin Robert W. Holloway Ronald D. Alvarez Carol Aghajanian Hua Min Karthik Devarajan Eric Ross Charles W. Drescher Andrew K. Godwin 2009Gynecologic Oncology2009,,:1
10C19MC miRNA-520G induces SP100 antiviral gene transcription and inhibits melanin production in skin cutaneous melanoma显示文摘SP100 is an antiviral protein that restricts the productive stage of human papillomavirus(HPV)and multiple other viruses,and viruses in turn block sUMO-1-mediated stabilization of SP100 and promotes its degradation(Table S1).Interferon(IFN)signaling could still produce more SP100 through transcription to counteract viruses.1 Viruses also disable the transcriptional up-regulation of SP100 to achieve persistent infection in hosts.Goodwin G.Jinesh Marian T.Smallin Nino Mtchedlidze Isha Godwin Marco Napoli Nicole Hackel Manali S.Phadke Avani A.Deshpande Xiaobo Li John H.Lockhart Jaden R.Baldwin Suehelay Acevedo-Acevedo Yifeng Gao Michelle A.Reiser Keiran S.M.Smalley Elsa R.Flores Andrew S.Brohl 2024Genes & Diseases2024,11,1:0
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