|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Prognosis of lymphotropic invasive micropapillary breast carcinoma analyzed by using data from the National Cancer Database显示文摘Background:Invasive micropapillary carcinoma(IMPC)is an uncommon subtype of breast cancer.Previous studies of this subtype demonstrated a higher propensity for lymph node metastases as compared with invasive ductal carci-noma(IDC).The purpose of the present study was to determine the clinical characteristics,outcomes,and propensity for lymph node metastasis of patients with IMPC of the breast recorded in the National Cancer Database(NCDB).Methods:Records of patients with IMPC diagnosed between 2004 and 2014 were retrieved from the NCDB.Log-rank test was performed to evaluate associations of clinical characteristics with overall survival(OS).Cox proportional hazards model was used to determine variables associated with OS.Results:Overall,2660 patients with IMPC met the selection criteria;the 5-year OS rate was 87.5%and 24.9%of patients had nodal involvement at presentation.Patients with≥4 positive lymph nodes had shorter OS than node-negative patients,whereas patients with 1-3 positive nodes had similar OS to node-negative patients.Age<65 years,receipt of radiotherapy,and estrogen receptor positivity were also associated with prolonged OS.The benefit of radiotherapy was limited to IMPC patients undergoing lumpectomy;there was no benefit for the patients undergoing mastectomy(regardless of nodal positivity/negativity).Conclusions:Favorable prognostic factors of IMPC patients included age<65 years,<4 positive lymph nodes,receipt of radiotherapy,and estrogen receptor positivity.The results presented herein suggest a survival benefit asso-ciated with radiotherapy in IMPC treatment,though this may be limited to the patients treated with lumpectomy. | Gary D.Lewis Yan Xing Waqar Haque Tejal Patel Mary Schwartz Albert Chen Andrew Farach Sandra S.Hatch E.Brian Butler Jenny Chang Bin S.Teh | 2019 | Cancer Communications2019，39，1： | 7 |
| 2 | Successful surgical management of ruptured umbilical hernias in cirrhotic patients显示文摘Acute umbilical hernia rupture in patients with hepatic cirrhosis and ascites is an unusual,but potentially lifethreatening complication,with postoperative morbidity about 70% and mortality between 60%-80% after supportive care and 6%-20% after urgent surgical repair.Management options include primary surgical repair with or without concomitant portal venous system decompression for the control of the ascites.We present a retrospective analysis of our centre's experience over the last 6 years.Our cohort consisted of 11 consecutive patients(median age:53 years,range:36-63 years) with advanced hepatic cirrhosis and refractory ascites.Appropriate patient resuscitation and optimisation with intravenous fluids,prophylactic antibiotics and local measures was instituted.One failed attempt for conservative management was followed by a successful primary repair.In all cases,with one exception,a primary repair with non-absorbable Nylon,interrupted sutures,without mesh,was performed.The perioperative complication rate was 25% and the recurrence rate 8.3%.No mortality was recorded.Median length of hospital stay was 14 d(range:4-31 d).Based on our experience,the management of ruptured umbilical hernias in patients with advanced hepatic cirrhosis and refractory ascites is feasible without the use of transjugular intrahepatic portosystemic shunt routinely in the preoperative period,provided that meticulous patient optimisation is performed. | Nikolaos A Chatzizacharias J Andrew Bradley Simon Harper Andrew Butler Asif Jah Emmanuel Huguet Raaj K Praseedom Michael Allison Paul Gibbs | 2015 | World Journal of Gastroenterology2015，21，10： | 4 |
| 3 | Putting things in place for fertilization: discovering roles for importin proteins in cell fate and spermatogenesis显示文摘Importin 蛋白质原来通过原子毛孔在蛋白质运输为他们的中央角色被描绘,唯一的细胞内部的入口到原子核。这个重要函数必须紧被调整由抄写因素和另外的原子蛋白质控制存取到 genomic DNA,到完成细胞的行为影响的适当调整房间命运。调停 Importin 的 nucleocytoplasmic 运输依靠他们货物的特定的识别,与到不同、重叠的蛋白质子集的每 importin 绑定。importin 功能的知识关于三个关键发展系统实质地膨胀了:胚胎的干细胞,肌肉房间和细菌排队。自从为调整 nucleocytoplasmic 运输的潜力被建议贡献精子发生,在十年,我们和其它证明了进原子核的渡船抄写因素执行的 importins 另外的角色,它控制房间命运。这评论从哺乳动物的精子发生的研究介绍关键调查结果揭示男富饶和不孕由产生的潜在的新小径。germline 开始的这些研究照亮 importin 蛋白质在管理细胞的区别的新方法,经由指导到不同细胞内部的分隔空间并且由决定细胞的压力回答的蛋白质包括。 | Kate L Loveland Andrew T Major Romaly Butler Julia C Young David A Jan Yoichi Miyamoto | 2015 | Asian Journal of Andrology2015，17，4： | 3 |
| 4 | CD133 expression is not restricted to stem cells, and both CD133^sup +^ and CD133^sup -^ metastatic colon cancer cells initiate tumors显示文摘 | Shmelkov Sergey V Butler Jason M Hooper Andrea T Hormigo Adilia Kushner Jared Milde Till Clair Ryan St Baljevic Muhamed White Ian Jin David K Chadburn Amy Murphy Andrew J Valenzuela David M Gale Nicholas W Thurston Gavin Yancopoulos George | 2008 | Journal of Clinical Investigation2008，，： | 2 |
| 5 | 采用美国国家癌症数据库数据分析淋巴浸润性微乳头状乳腺癌的预后显示文摘背景与目的浸润性微乳头状癌(invasive micropapillary carcinoma,IMPC)是乳腺癌中一种罕见的亚型。已有研究表明,与浸润性导管癌(invasive ductal carcinoma,IDC)相比,该亚型更易发生淋巴结转移。本研究旨在明确美国国家癌症数据库(National Cancer Database,NCDB)中记录的乳腺IMPC患者的临床特征、结局和淋巴结转移倾向性。方法从NCDB中检索2004–2014年之间诊断为IMPC患者的病历,并对其进行log-rank检验以评估临床特征与总生存期(overall survival,OS)的相关性。采用Cox比例风险模型确定OS相关因素。结果本研究共纳入2660例IMPC患者。5年OS率为87.5%,24.9%患者出现淋巴结转移。阳性淋巴结数≥4的患者的OS短于阴性淋巴结的患者,而阳性淋巴结数为1–3的患者的OS与阴性淋巴结患者相似。年龄<65岁、接受放疗和雌激素受体阳性也与OS延长有关。放疗仅对接受肿块切除术的IMPC患者有效,对进行乳房切除术的患者无效(无论淋巴结阳性/阴性)。结论IMPC患者的有利预后因素包括年龄<65岁、阳性淋巴结数<4、接受放疗和雌激素受体阳性。本研究结果表明,IMPC患者的生存获益与放疗相关,但可能仅限于经肿块切除术治疗的患者。 | Gary DLewis Yan Xing Waqar Haque Tejal Patel Mary Schwartz Albert Chen Andrew Farach Sandra SHatch EBrian Butler Jenny Chang Bin S.Teh | 2020 | 癌症2020，39，2： | 2 |
| 6 | 脑卒中后白质完整性与上肢运动功能的关系显示文摘目的应用扩散张量成像技术测量偏瘫患者内囊后肢的各向异性(FA)值,分析皮质脊髓束完整性与患侧上肢运动功能的关系。方法选择17例亚急性期脑卒中后偏瘫患者,测量患侧及健侧内囊后肢FA值,并计算FA非对称比值,临床检测包括上肢运动功能指标(WMFT)及运动功能、平衡、感觉及关节功能综合评价指标(FM),利用线性相关分析FA非对称比值与患手FM评分、WMFT非对称比值及log WMFT之间的相关关系。结果患手运动功能评分与内囊后肢FA非对称比值显著相关,FA非对称性比值与患手FM(R2=0.655,P<0.002)呈线性负相关,与WMFT非对称性比值(R2=0.649,P<0.002)、lgWMFT(R2=0.636,P=0.002)以及握力非对称性比值(R2=0.414,P=0.02)均呈线性正相关。结论偏瘫患者亚急性期皮质脊髓束完整性与上肢运动功能显著相关;利用扩散张量成像技术可早期监测皮质脊髓束的完整性。 | 邱明国 Chun Chun NI Justin RAJENDRA Andrew J. BUTLER | 2009 | 中国医学影像技术2009，，12： | 2 |
| 7 | Designing a Core IT Artefact for Knowledge Manage- ment Systems using Participatory Action Research in a Govern- ment and a non-government Organisation显示文摘 | Tom Butler Joseph Feller Andrew Pope Bill Emerson Ciaran Murphy | 2008 | Journal of Strate- gic Information Systems2008，，17： | 1 |
| 8 | A Meta-analysis of the Efficacy of Anodal Transcranial Direct Current Stimulation for Upper Limb Motor Recovery in Stroke Survivors显示文摘 | Andrew J. Butler | 2012 | Journal of Hand Therapy2012，，： | 1 |
| 9 | Once-Daily, High-Concentration MMX Mesalamine in Active Ulcerative Colitis显示文摘 | Michael A. Kamm William J. Sandborn Miguel Gassull Stefan Schreiber Lechoslaw Jackowski Todd Butler Andrew Lyne David Stephenson Mary Palmen Raymond E. Joseph | 2007 | Gastroenterology2007，，： | 1 |
| 10 | Biological control of cyanobacteria: principles and possibilities显示文摘 | D.C. Sigee R. Glenn M.J. Andrews E.G. Bellinger R.D. Butler H.A.S. Epton R.D. Hendry | 1999 | Hydrobiologia1999，，0： | 1 |
| 11 | Reduction of post-traumatic brain injury and free radical production by inhibition of the caspase- 1 cascade 显示文摘 | Fink KB Andrews LJ Butler WE | 1999 | Neuroscience1999，94，4： | 1 |
| 12 | The MIQ-RS: A Suitable Option for Examining Movement Imagery Ability显示文摘 | Melanie Gregg Craig Hall Andrew Butler | 2007 | Evidence-Based Complementary and Alternative Medicine2007，，2： | 1 |
| 13 | A prospective, modernized treatment protocol for periprosthetic femur fractures显示文摘 | Paul J. Duwelius Andrew H. Schmidt Richard F. Kyle Vanessa Talbott Thomas J. Ellis Jay B.V. Butler | 2004 | Orthopedic Clinics of North America2004，，4： | 1 |
| 14 | A radiation- driven model for crown fire spread 显示文摘 | BUTLER B W FINNEY M A ANDREWS P L | 2004 | Canada Journal of Forest Research2004，34，： | 1 |
| 15 | Determination of aluminium in natural water samples显示文摘 | Juliette Tria Edward C.V. Butler Paul R. Haddad Andrew R. Bowie | 2007 | Analytica Chimica Acta2007，，2： | 1 |
| 16 | Once-Daily, High-Concentration MMX Mesalamine in Active Ulcerative Colitis显示文摘 | Michael A. Kamm William J. Sandborn Miguel Gassull Stefan Schreiber Lechoslaw Jackowski Todd Butler Andrew Lyne David Stephenson Mary Palmen Raymond E. Joseph | 2007 | Gastroenterology2007，，1： | 1 |
| 17 | Neural melanocortin receptors in obesity and related metabolic disorders显示文摘 | Clemence Girardet Andrew A. Butler | 2013 | BBA - Molecular Basis of Disease2013，，： | 1 |
| 18 | Reduction of post-tranmatic brain injmy and free radical production by inhibition of the caspase-1 cascade显示文摘 | Fink KB Andrews LJ Butler WE | 1999 | Neuroscience1999，94，4： | 1 |
| 19 | The MIQ-RS:a suitable option for examining movement imagery ability显示文摘 | Melanie Greeg Craig Hall Andrew Butler | | 0，，02： | 1 |
| 20 | Forecasting the Future of Cardiovascular Disease in the United States: A Policy Statement From the American Heart Association显示文摘 | Paul A. Heidenreich Justin G. Trogdon Olga A. Khavjou Javed Butler Kathleen Dracup Michael D. Ezekowitz Eric Andrew Finkelstein Yuling Hong S. Claiborne Johnston Amit Khera Donald M. Lloyd-Jones Sue A. Nelson Graham Nichol Diane Orenstein Peter W.F. Wilso | 2011 | Circulation2011，，8： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员