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157篇 您的检索式：作者名="Palmen"

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	题名	作者	年代	出处	被引量
1	The microsatellite polymorphism of heme oxygenase-1 is associated with baseline plasma IL-6 level but not with restenosis after coronary in-stenting显示文摘Background Vascular smooth muscle cells (VSMCs) can express heme-oxygenase (HO), a rate-limiting enzyme in the degradation of heme to bilirubin, ferritin and carbon monoxide (CO). VSMC-derived CO can suppress VSMC proliferation and may serve as an antiproliferation factor. The promoter region of HO-1 shows a polymorphism with different (GT)_n repeats that has been reported to differently induce gene expression. The objective of this study was to examine the effect of this variation on the occurrence of restenosis after in-stent treatment in patients with coronary artery disease. Methods Candidates who underwent coronary stent implantation were genotyped for the HO-1 promoter polymorphism using polymerase chain reaction (PCR) and automated DNA capillary sequencer. Serum levels of IL-6 and C-reactive protein (CRP) were obtained at baseline, 24 hours and 48 hours after stenting. The primary end point for the study was angiographic evidence of in-stent restenosis at 6 months. All parameters for evaluation of restenosis were analysed by quantitatve computer-assisted angiographic analysis (QCA). Results One hundred and eighty-seven patients who underwent coronary stent implantation were studied of whom 27.8% showed ≥50% restenosis after 6 months. The distribution of (GT)_n repeats of all patients in the promoter region of HO-1 genotype ranged from 22 to 42, with (GT)_ 25 and (GT)_ 32 being the two most common alleles. The allelic repeats were divided into the short class (S) with 29 (GT)_n, the middle class (M) with 30-37 (GT)_n and the long class (L) with 38 (GT)_n. There was no significant difference in the restenosis between the genotype groups or between post operation levels of inflammation markers, but carriers of the S allele (n=120) had 33.3% lower baseline IL-6 compared with non-S carriers (n=67, P=0.0008). Conclusions Although no association was observed between the HO-1 promoter polymorphism aod coronary in-stent restenosis following the stent procedure, the association with plasma IL-6 levels suggests that HO-1 S allele might protect from the atherosclerotic inflammatory process.	LI Ping Mohamed A. Elrayess Abuzeid H. Gomma Jutta Palmen Emma Hawe Kim M. Fox Steve E. Humphries	2005	Chinese Medical Journal2005，，18：	6
2	Impact of age on transcatheter aortic valve implantation outcomes:a comparison of patients aged≤ 80 years versus patients > 80 years显示文摘	Frank van der Kley Philippe J van Rosendael Spyridon Katsanos Vasileios Kamperidis Nina A Marsan Ioannis Karalis Arend de Weger Meindert Palmen Jeroen J Bax Martin J Schalij Victoria Delgado	2016	Journal of Geriatric Cardiology2016，13，1：	2
3	Nephrin TRAP mice lack slit diaphragms and show fibrotic glomemli and cystic tubular lesions 显示文摘	RANTANEN M PALMEN T PATARI A	2002	J Am Soe Nephrol2002，13，6：	1
4	Once-Daily, High-Concentration MMX Mesalamine in Active Ulcerative Colitis显示文摘	Michael A. Kamm William J. Sandborn Miguel Gassull Stefan Schreiber Lechoslaw Jackowski Todd Butler Andrew Lyne David Stephenson Mary Palmen Raymond E. Joseph	2007	Gastroenterology2007，，：	1
5	Epithelioid hemangioendothelioma of the lung:clinical and patholngical pitfalls显示文摘	Van Kasteren ME Van der Wurff AA Palmen FM	1995	Eur Respir1995，8，9：	1
6	Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterizedby Thl and Th2 cytokines 显示文摘	Dieleman L A Palmen M J	1998	Clin Exp Immunol1998，114，3：	1
7	On the mean meridional circulations in the northern hemisphere during the winter season 显示文摘	Palmen E Vuorela L A	1963	Q J R Meteorol Soc1963，89，379：	1
8	Chronic experimental colitis induced by dextran sulphate sodium (DSS) is characterized by Thl and Th2 cytokines 显示文摘	Dieleman LA Palmen MJ Akol H Bloemena E Pena AS Meuwissen SG Van Rees EP	1998	Clin Exp Immunol1998，114，：	1
9	Criteria document for Swedish Occupational Standards : Cobalt and Cobalt Compounds 显示文摘	Palmen N	2005	ArbetslivsInstitutet2005，，：	1
10	On the formation and structure of tropical hurricanes 显示文摘	PALMEN E	1948	Geophysiea1948，，3：	1
11	Nephrin is expressed in the pancreatic beta cells 显示文摘	Palmen T Ahola H Palgi J	2001	Diabetologia2001，44，10：	1
12	Chronic experimental colitis induced by dextran sulphate sodium(DSS)is Characterized by Th1 and Th2 cytokines显示文摘	Dieleman LA Palmen MJ Akol H Bloemena E Pena AS Meuwissen SG Van Rees EP	1998	Clin ExP Immunol1998，114，：	1
13	Time-temperature Superposition for Polymeric Blends显示文摘	Van Gurp M Palmen	1998	Journal of Rheology Bulletin1998，67，：	1
14	Interaction of Endogenous Nephrin and CD2-Associated Protein in Mouse Epithelial M-1 Cell Line显示文摘	Palmen T Lehtonen S Ora A	2002	J Am Soc Nephrol2002，13，7：	1
15	Vertical circulation and release of kinetic energy during the development of hurricane hazel into an extratropical storm显示文摘	Palmen E	1958	Tellus1958，10，1：	1
16	A cross-sectional study among detergent workers exposed to liquid detergent enzymes显示文摘	van Rooy F G Houba R Palmen N	2009	Occup Environ Med2009，66，11：	1
17	Interaction of endogenous nephrin and CD2-associated protein in mouse epithelial M-1 cell line显示文摘	Palmen T Lehtonen S Ora A	2002	J Am Soc Nephrol2002，13，7：	1
18	Cardiac remodeling after myocardial infarction is impaired in IGF-Ⅰ deficient mice显示文摘	Palmen M Daemen M Bronsaer R	2002	Cardiovasc Res2002，50，：	1
19	Filtrin is a novel member of nephrin-like proteins显示文摘	Ihalmo P Palmen T Ahola H	2003	Biochem Biophys Res Commun2003，300，2：	1
20	Chronic ex- perimental colitis induced by dextran sulphate sodium (DSS) is characterized by Thl and Th2 cytokines显示文摘	Dieleman L A Palmen M J Akol H	1998	Clin Exp Immunol1998，114，：	1

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