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| 1 | Texture analysis on parametric maps derived from dynamic contrast-enhanced magnetic resonance imaging in head and neck cancer显示文摘AIM: To investigate the merits of texture analysis on parametric maps derived from pharmacokinetic modeling with dynamic contrast-enhanced magnetic resonance imaging(DCE-MRI) as imaging biomarkers for the prediction of treatment response in patients with head and neck squamous cell carcinoma(HNSCC). METHODS: In this retrospective study,19 HNSCC patients underwent pre- and intra-treatment DCEMRI scans at a 1.5T MRI scanner. All patients had chemo-radiation treatment. Pharmacokinetic modeling was performed on the acquired DCE-MRI images,generating maps of volume transfer rate(Ktrans) and volume fraction of the extravascular extracellular space(ve). Image texture analysis was then employed on maps of Ktrans and ve,generating two texture measures: Energy(E) and homogeneity.RESULTS: No significant changes were found for the mean and standard deviation for Ktrans and ve between pre- and intra-treatment(P > 0.09). Texture analysis revealed that the imaging biomarker E of ve was significantly higher in intra-treatment scans,relative to pretreatment scans(P < 0.04). CONCLUSION: Chemo-radiation treatment in HNSCC significantly reduces the heterogeneity of tumors. | Jacobus FA Jansen Yonggang Lu Gaorav Gupta Nancy Y Lee Hilda E Stambuk Yousef Mazaheri Joseph O Deasy Amita Shukla-Dave | 2016 | World Journal of Radiology2016，8，1： | 5 |
| 2 | Metastatic clear cell variant of hepatocellular carcinoma with an occult hepatic primary显示文摘Metastatic clear cell carcinomas are commonly seen in the kidney and lung. Clear cell variant of hepatocellular carci- noma is an uncommon tumour. Diagnosis is usually made by correlation of histopathology. tumour markers and im- munohistochemistry, especially HepPar 1. In this unusual case of metastatic clear cell carcinoma presenting as Sister Mary Joseph’s nodule, no primary evidence was observed radiologically in the liver, but the level of alfa fetoprotein was markedly elevated. Metastatic clear cell carcinoma of the liver with an occult hepatic primary was diagnosed by immunohistochemical profile of the tumour. | Samir ShahSamir Shah Sudeep Gupta Tanuja Shet Amita Maheshwari Rekha Wuntkal and Kunisshery Mallath Mohandas | 2005 | Hepatobiliary & Pancreatic Diseases International2005，4，2： | 3 |
| 3 | Ferromagnetism above Room Temperature in Bulk and Transparent Thin Films of Mn-doped ZnO显示文摘 | Amita Gupta Rao K V | 2003 | Nature Materials2003，2，： | 1 |
| 4 | Fetotoxicity of warfarin anticoagulation显示文摘 | Sumit Mehndiratta Amita Suneja Bindiya Gupta Shuchi Bhatt | 2010 | Archives of Gynecology and Obstetrics2010，，3： | 1 |
| 5 | Maternal pneumococcal capsular IgG antibodies and transplacental transfer are lower in South Asian HIV-infected mother-infant pairs显示文摘 | Amita Gupta Jyoti S. Mathad Wei-Teng Yang Harjot K. Singh Nikhil Gupte Vidya Mave Renu Bharadwaj K. Zaman Eliza Roy Robert C. Bollinger Ramesh Bhosale Mark C. Steinhoff | 2014 | Vaccine2014，，： | 1 |
| 6 | QTL analysis for some quantitative traits in bread wheat显示文摘Quantitative trait loci (QTL) analysis was conducted in bread wheat for 14 important traits utilizing data from four different mapping populations involving different approaches of QTL analysis. Analysis for grain protein content (GPC) sug- gested that the major part of genetic variation for this trait is due to environmental interactions. In contrast, pre-harvest sprouting tolerance (PHST) was controlled mainly by main effect QTL (M-QTL) with very little genetic variation due to environmental interactions; a major QTL for PHST was detected on chromosome arm 3AL. For grain weight, one QTL each was detected on chromosome arms 1AS, 2BS and 7AS. QTL for 4 growth related traits taken together detected by different methods ranged from 37 to 40; nine QTL that were detected by single-locus as well as two-locus analyses were all M-QTL. Similarly, single-locus and two-locus QTL analyses for seven yield and yield contributing traits in two populations respectively allowed detection of 25 and 50 QTL by composite interval mapping (CIM), 16 and 25 QTL by multiple-trait composite interval mapping (MCIM) and 38 and 37 QTL by two-locus analyses. These studies should prove useful in QTL cloning and wheat improvement through marker aided selection. | PUSHPENDRA Kumar Gupta HARINDRA Singh Balyan PAWAN Laxminarayan Kulwal NEERAJ Kumar AJAY Kumar REYAZUL Rouf Mir AMITA Mohan JITENDRA Kumar | 2007 | Journal of Zhejiang University-Science B(Biomedicine & Biotechnology)2007，8，11： | 1 |
| 7 | An Investigation of Melt Rheology and Thermal Stabi- lity of Poly(lactic acid)/Poly(butylene succinate) Nano- composites显示文摘 | Amita Bhatia Rahul K Gupta Sati N Bhattaeharya el al | 2009 | Journal of Applied Polymer Science2009，114，28： | 1 |
| 8 | Room temperature spintronic material Mn-doped ZnO revis ited显示文摘 | Parmanand Sharma Amita Gupta Frank J Owens | 2004 | Journal of Magnetism and Magnetic Materials2004，282，： | 1 |
| 9 | Characterization of cytochrome P450 monooxygenases isolated from trichome enriched fraction of Artemisia annua L. leaf显示文摘 | Amita Misra Chandan S. Chanotiya Madan M. Gupta Upendra N. Dwivedi Ajit K. Shasany | 2012 | Gene2012，，2： | 1 |
| 10 | Comparative neurotoxicity of cadmium in growing and adult rats after repeated administration显示文摘 | Amita Gupta Alka Gupta Murthy RC | 1990 | Biochemistry International1990，21，1： | 1 |
| 11 | Basic dye (methylene blue) removal from simulated wastewater by adsorption using Indian Rosewood sawdust: a timber industry waste显示文摘 | V.K. Garg Moirangthem Amita Rakesh Kumar Renuka Gupta | 2004 | Dyes and Pigments2004，，3： | 1 |
| 12 | Synthesis of alumina powder by the urea–glycine–nitrate combustion process: a mixed fuel approach to nanoscale metal oxides显示文摘 | Amit Sharma Amita Rani Ajay Singh O. P. Modi Gaurav K. Gupta | 2014 | Applied Nanoscience2014，，3： | 1 |
| 13 | 显示文摘 | Amita Gupta Rao K V | 2003 | Nature Materials2003，2673，： | 1 |
| 14 | Clinical pharmacology of trastuzumab emtansine (T-DM1): an antibody–drug conjugate in development for the treatment of HER2-positive cancer显示文摘 | Sandhya Girish Manish Gupta Bei Wang Dan Lu Ian Krop Charles Vogel Howard Burris III Patricia LoRusso Joo-Hee Yi Ola Saad Barbara Tong Yu-Waye Chu Scott Holden Amita Joshi | 2012 | Cancer Chemotherapy and Pharmacology2012，，5： | 1 |
| 15 | Dyes Pigm显示文摘 | Garg V K Amita M Kumar R Gupta R | 2004 | 63(3):2432004，63，3： | 1 |
| 16 | Co-positivity of anti-dengue virus and anti-Japanese encephalitis virus IgM in endemic area:co-infection or cross reactivity?显示文摘Objective:To report high co-positivity of anti-dengue virus(DV)and anti-Japanese encephalitis virus(JEV)IgM in an area endemic for both the viruses and to discuss the possibilities of coinfection.Methods:Serum samples from the patients who presented with fever,suspected central nervous system infection and thrombocytopenia,were tested for anti-DV IgM and antiJEV IgM antibodies.Conventional reverse transcriptase polymerase chain reaction was done for detection of DV RNA and JEV RNA.Results:Of 1 410 patient sera tested for anti-DV and antiJEV antibodies,129(9.14%)were co-positive for both.This co-positivity was observed only in those months when anli-JEV IgM positivily was high.Tilers of both anli-DV IgM and anti-JEV IgM were high in most of the co-positive eases.Among these 129 co-positive cases,76 were lesled by conventional reverse Iranscriplase polymerase chain reaction for both flaviviruses,of which eight cases were co-positive for DV and JEV.Conclusions:Co-infection with more than one fluvivirus species can occur in hyperendemic areas. | Kaleshwar Prasad Singh Gitika Mishra Parul Jain Nidhi Pandey Rachna Nagar Shikha Gupta Shantanu Prakash Om Prakash Danish Nasar Khan Sakshi Shrivastav Desh Deepak Singh Amita Jain | 2014 | Asian Pacific Journal of Tropical Medicine2014，7，2： | 0 |
| 17 | Surgical route and pathological risk factors in early cervical cancer-Node Zero(SURPEC-N0)显示文摘Aim:The aim of this study is to compare disease-free survival(DFS)and overall survival(OS)in patients with stage I cervical cancer(≤4cms,lymph node-negative)undergoing open radical hysterectomy(ORH)vs.minimally invasive radical hysterectomy(MIRH).Methods:All patients undergoing radical hysterectomy between January 2012-December 2018 from the largest tertiary referral cancer centre were included.A 1:1 propensity matching was done based on four independent prognostic factors to compare DFS and OS with the route of surgery.Results:One hundred and ninety-nine patients were included during the study period.The median age of the cohort was 50 years.The median follow-up of patients was 47 months.Following 1:1 propensity matching,a total of 174 patients were analysed for DFS and OS in ORH(n=87)and MIRH(n=87)groups.Protective measure was used in two-thirds of the patients during MIRH.Twenty-nine patients(16.7%)had recurrences.For the matched cohort(n=174),the DFS at 36 and 60 months was 84.8%(78.1%-89.6%)and 81%(73.4%-86.6%)respectively and the OS was 96.5%(91.7%-98.5%)and 95.6%(90.3%-98%)respectively.There was no statistically significant difference in DFS or OS between ORH and MIRH.Conclusion:The present study showed no difference in oncological outcomes in MIRH compared to ORH.Retrospective audits on patient characteristics such as screening/vaccination history along with surgical technique/load and matching for crucial risk factors should be factored in future studies to eliminate the possible methodological errors. | T S Shylasree Stuti Gupta Akshay Patil Pooja Singh Amita Maheshwari Santosh Menon Supriya Chopra Lavanya Gurram Palak Popat Umesh Mahantshetty Rajendra Kerkar | 2022 | Journal of Cancer Metastasis and Treatment2022，8，1： | 0 |
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