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| 1 | Parenchymal-sparing liver surgery in patients with colorectal carcinoma liver metastases显示文摘Liver resection is the treatment of choice for patients with colorectal liver metastases(CLM).However,major resections are often required to achieve R0 resection,which are associated with substantial rates of morbidity and mortality.Maximizing the amount of residual liver gained increasing significance in modern liver surgery due to the high incidence of chemotherapyassociated parenchymal injury.This fact,along with the progressive expansion of resectability criteria,has led to the development of a surgical philosophy known as 'parenchymal-sparing liver surgery'(PSLS).This philosophy includes a variety of resection strategies,either performed alone or in combination with ablative therapies.A profound knowledge of liver anatomy and expert intraoperative ultrasound skills are required to perform PSLS appropriately and safely.There is a clear trend toward PSLS in hepatobiliary centers worldwide as current evidence indicates that tumor biology is the most important predictor of intrahepatic recurrence and survival,rather than the extent of a negative resection margin.Tumor removal avoiding the unnecessary sacrifice of functional parenchyma has been associated with less surgical stress,fewer postoperative complications,uncompromised cancer-related outcomes and higher feasibility of future resections.The increasing evidence supporting PSLS prompts its consideration as the gold-standard surgical approach for CLM. | Fernando A Alvarez Rodrigo Sanchez Claria Sebastian Oggero Eduardo de Santibanes | 2016 | World Journal of Gastrointestinal Surgery2016，8，6： | 8 |
| 2 | Influence of genes,sex,age and environment on the onset of autoimmune hepatitis显示文摘The pathogenesis of autoimmune hepatitis (AIH) is complex. However,it is believed that a susceptible individual,owing to his genetic background,sex and age,can develop the disease following exposure to an environmental trigger. Autoimmune hepatitis does not follow a Mendelian pattern of inheritance; hence no single causative genetic locus has been identified. However,several genes,inside and outside the HLA locus,have been linked to an increased susceptibility to AIH. Epidemiological evidence also suggests that the sex and age of the patient plays a role in AIH pathogenesis as the disease onset occurs mainly in the two first decades of life and a higher disease incidence is observed in females. No environmental trigger has been identified,but several have been proposed,mainly viruses and xenobiotics. This article aims at reviewing the current knowledge on susceptibility factors leading to AIH and putative triggers,emphasizing fundamental mechanisms responsible for the break of liver immunological tolerance. | Kathie Béland Pascal Lapierre Fernando Alvarez | 2009 | World Journal of Gastroenterology2009，15，9： | 8 |
| 3 | Intraoperative Management and Repair of Bile Duct Injuries Sustained during 10,123 Laparoscopic Cholecystectomies in a High-Volume Referral Center显示文摘 | Juan Pekolj Fernando A. Alvarez Martin Palavecino Rodrigo Sánchez Clariá Oscar Mazza Eduardo de Santiba?es | 2013 | Journal of the American College of Surgeons2013，，5： | 3 |
| 4 | Effect of climate and altitude on plant community composition and richness in Brazilian inselbergs显示文摘Plant communities are shaped by multiple factors along environmental gradients;however,studies are limited on how environmental filtering drives community composition and species richness on tropical inselbergs.We evaluate the influence of altitude and climatic variables related to temperature and precipitation on plant community composition and species richness on Brazilian inselbergs.We assume as a premise that both climate and altitude would induce changes on plant community composition and species richness at the local level.We used plant inventory data from 370 sampling units across four inselberg sites in the Atlantic Forest of Espírito Santo State,south-eastern Brazil.We tested the univariate and multivariate effects of altitude and climate variables on community composition and species richness with multiple models.Differences in species richness between inselbergs were evaluated using sample-based data to estimate rarefaction and extrapolation curves.In addition,differences in species composition and taxonomic beta diversity were examined via novel frequency-based metrics.A contrasting climate pattern was observed between the inselberg sites,with south sites being wet compared to the dry conditions found in northern sites.Species richness by rarefaction showed a similar pattern within regional sites;however,there were marked differences between regions.Species richness and beta diversity showed significant differences among sites,with higher values in southern sites than in northern sites.In a multi-model comparison between inselberg sites,altitude significantly influenced community composition and species richness and explained more variance than climate models.This finding suggested that climate could act to some extent on these tropical inselbergs;however,altitude was a better predictor of plant community composition and species richness at the local level. | Herval Vieira PINTO-JUNIOR Pedro Manuel VILLA Luis Fernando Tavares de MENEZES Miriam Cristina Alvarez PEREIRA | 2020 | Journal of Mountain Science2020，17，8： | 2 |
| 5 | Ileocolic intussusception due to intestinal metastatic melanoma. Case report and review of the literature显示文摘 | Fernando A. Alvarez Matías Nicolás Jeremías Goransky Carlos A. Vaccaro Axel Beskow Demetrio Cavadas | 2011 | International Journal of Surgery Case Reports2011，，6： | 2 |
| 6 | Bio-mineralization of organic matter in dairy wastewater, as affected by pH, the evolution of ammonium and phosphates显示文摘 | Emilia Guillén Jiménez Paloma Alvarez Mateos Fernando Romero Guzmán | 2000 | Water Res2000，34，4： | 1 |
| 7 | An economic optimization model for irrigation water management显示文摘 | Jose Fernando Ortega Alvarez | 2004 | Irrigation Science2004，，23： | 1 |
| 8 | Fenton Reagent Advanced Oxidation of Polynuclear Aromatic Hydrocarbons in Water显示文摘 | Fernando J. Beltrán Manuel González Francisco J. Ribas Pedro Alvarez | 1998 | Water Air and Soil Pollution (-)1998，，3： | 1 |
| 9 | Using Asset Prices to Measure the Cost of Business Cycles 显示文摘 | Alvarez Fernando Urban Jermann | 2004 | Journal of Political Economy2004，112，6： | 1 |
| 10 | Using Asset Prices to Measure the Cost of Business Cycles显示文摘 | Alvarez Fernando Jermann Urban J | 2004 | Journal of Political Economy2004，112，： | 1 |
| 11 | HLA Class II influences humoral autoimmunity in patients with type 2 autoimmune hepatitis显示文摘 | Idriss Djilali-Saiah Amin Fakhfakh Hamida Louafi Sophie Caillat-Zucman Dominique Debray Fernando Alvarez | 2006 | Journal of Hepatology2006，，6： | 1 |
| 12 | Incidence, 30-day case-fatality rate, and prognosis of stroke in Iquique, Chile: a 2-year community-based prospective study (PISCIS project)显示文摘 | Pablo M Lavados Claudio Sacks Liliana Prina Arturo Escobar Claudia Tossi Fernando Araya Walter Feuerhake Marcelo Galvez Rodrigo Salinas Gonzalo Alvarez | 2005 | The Lancet2005，，9478： | 1 |
| 13 | Isolable 1,2 -Oxaphosphetanes: From Curiosities to Starting Materials for the Synthesis of Olefins 显示文摘 | Fernando Lopez - Ortiz Jesus Garcla Lopez Ramon alvarez Manzaneda | 2004 | Mini - Reviews in Organic Chemistry2004，，1： | 1 |
| 14 | Incidence of childhood cancer among Mexican children registered under a public medical insurance program显示文摘 | Roberto Rivera‐Luna Cecilia Correa‐González Eduardo Altamirano‐Alvarez Fernando Sánchez‐Zubieta Rocio Cárdenas‐Cardós Gabriela Escamilla‐Asian Alberto Olaya‐Vargas Aurora Bautista‐Marquez Manuel Aguilar‐Romo | 2012 | Int. J. Cancer2012，，： | 1 |
| 15 | Pathogenesis of autoimmune hepatitis: from break of tolerance to immune-mediated hepatocyte apoptosis显示文摘 | Pascal Lapierre Kathie Béland Fernando Alvarez | 2007 | Translational Research2007，，3： | 1 |
| 16 | Portal Vein Complications after Pediatric Liver Transplantation显示文摘 | Fernando Alvarez | 2012 | Current Gastroenterology Reports2012，，3： | 1 |
| 17 | Homoclinic Chaos in 2-DOF Robot Manipulators Driven by PD Controllers显示文摘 | FERNANDO VERDUZCO JOAQUIN ALVAREZ | 2000 | Non-Linear Dynamics2000，21，： | 1 |
| 18 | Anti-LC1 autoantibodies in patients with chronic hepatitis C virus infection显示文摘 | Kathie Béland Pascal Lapierre Gabriel Marceau Fernando Alvarez | 2003 | Journal of Autoimmunity2003，，2： | 1 |
| 19 | MHC class II sequences of susceptibility and protection in Mexicans with autoimmune hepatitis显示文摘 | Miriam Nohemí Vázquez-García Carmen Aláez Angélica Olivo Héctor Debaz Elva Pérez-Luque Ana Burguete Silvia Cano Gabriela de la Rosa Norma Bautista Arturo Hernández José Bandera Luis Fernando Torres David Kershenobich Fernando Alvarez Clara Gorodezky | 1998 | Journal of Hepatology1998，，6： | 1 |
| 20 | A Base Integer Programming Model and Benchmark Suite for Liner-Shipping Network Design显示文摘 | Brouer Berit D Alvarez J Fernando Plum Christian E M Pisinger David Sigurd Mikkel M | 2014 | Transportation Science2014，，： | 1 |
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