|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Endoscopic submucosal dissection for premalignant lesions and noninvasive early gastrointestinal cancers显示文摘AIM: To investigate the indication, feasibility, safety, and clinical utility of endoscopic submucosal dissection (ESD) in the management of various gastrointestinal pathologies. METHODS: The medical records of 60 consecutive patients (34 female, 26 male) who underwent ESD at the gastroenterology department of Kocaeli University from 2006-2010 were examined. Patients selected for ESDhad premalignant lesions or non-invasive early cancers of the gastrointestinal tract and had endoscopic and histological diagnoses. Early cancers were considered to be confined to the submucosa, with no lymph node involvement by means of computed tomography and endosonography. RESULTS: Sixty ESD procedures were performed. The indications were epithelial lesions (n = 39) (33/39 adenoma with high grade dysplasia, 6/39 adenoma with low grade dysplasia), neuroendocrine tumor (n = 7), cancer (n = 7) (5/7 early colorectal cancer, 2/7 early gastric cancer), granular cell tumor (n = 3), gastrointestinal stromal tumor (n = 2), and leiomyoma (n = 2). En bloc and piecemeal resection rates were 91.6% (55/60) and 8.3% (5/60), respectively. Complete and incomplete resection rates were 96.6% (58/60) and 3.3% (2/60), respectively. Complications were major bleeding [n = 3 (5%)] and perforations [n = 5 (8.3%)] (4 colon, 1 stomach). Two patients with colonic perforations and two patients with submucosal lymphatic and microvasculature invasion (1 gastric carcinoid tumor, 1 colonic adenocarcinoma) were referred to surgery. During a mean follow-up of 12 mo, 1 patient with adenoma with high grade dysplasia underwent a second ESD procedure to resect a local recurrence. CONCLUSION: ESD is a feasible and safe method for treatment of premalignant lesions and early malignant gastrointestinal epithelial and subepithelial lesions. Successful en bloc and complete resection of lesions yield high cure rates with low recurrence. | Sadettin Hulagu Omer Senturk Cem Aygun Orhan Kocaman Altay Celebi Tolga Konduk Deniz Koc Goktug Sirin Ugur Korkmaz Ali Erkan Duman Neslihan Bozkurt Gokhan Dindar Tan Attila Yesim Gurbuz Orhan TarcinDivision of Gastroenterology Derince State Hospital Kocaeli 41900 Turkey Cem Kalayci | 2011 | World Journal of Gastroenterology2011，17，13： | 23 |
| 2 | GRAIN BOUNDARY REORGANIZATION IN INTERMETALLIC COMPOUNDS NiAl AND FeAl显示文摘Computer simulation of grain boundaries(GB) was carried out in Fe and ordered alloys NiAl and FeAl with B2 superlattice. In this work symmetrical tilt grain boundaries =5[100](012) and = 5[100](013) are studied. The atomic interaction has been described by Morse empirical central- force potentials.The atomic structure and energy of GB were investigated by means of construction of -surface using full atomic relaxation by method of molecular statics. It is shown that = 5 tilt GBs in Fe, Ni3Al and NiAl have several steady states. Comparison of our results with geometrical model of coincidence site lattice (CSL) was carried out. GBs in model CSL are unstable, the stabilization is achieved by additional displacement at some vector along the plane of defect. | M.D. Starostenkov, B. F. Demyanov, E.A. Kuklina and E. G. Sverdlova General Physics Department, Altai State Technical University, Lenin st 46, Barnaul, 656099, Russia | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，2： | 13 |
| 3 | Does vitamin D affect disease severity in patients with ankylosing spondylitis?显示文摘 | Bekir Durmus Zuhal Altay Ozlem Baysal Yuksel Ersoy | 2012 | Chinese Medical Journal2012，，14： | 10 |
| 4 | Which factors determine exocrine pancreatic dysfunction in diabetes mellitus?显示文摘The exocrine structure is significantly affected by diabetes because of endocrine structure-function disorder within the pancreas. Exocrine pancreatic dysfunction (EPD) is the general name of the malabsorption process resulting from inadequate production, release, decreased activation, and/or insufficient degradation of enzymes required for digestion from pancreatic acinar cells. It is important to diagnose patients early and correctly, since there may be both macro- and micro-nutrient deficiency in EPD. In this paper, EPD, the diabetes- EPD relationship, and the predictive, effective factors affecting the emergence of EPD are briefly explained and summarized with contemporary literature and our experienced based on clinical, lab, and radiological findings. | Mustafa Altay | 2019 | World Journal of Gastroenterology2019，25，22： | 7 |
| 5 | Use of platelet lysate for bone regeneration-are we ready for clinical translation?显示文摘Current techniques to improve bone regeneration following trauma or tumour resection involve the use of autograft bone or its substitutes supplemented with osteoinductive growth factors and/or osteogenic cells such as mesenchymal stem cells(MSCs).Although MSCs are most commonly grown in media containing fetal calf serum,human platelet lysate(PL) offers an effective alternative.Bone marrow- derived MSCs grown in PLcontaining media display faster proliferation whilst maintaining good osteogenic differentiation capacity.Limited pre-clinical investigations using PL-expanded MSCs seeded onto osteoconductive scaffolds indicate good potential of such constructs to repair bone in vivo.In an alternative approach,nude PL-coated scaffolds without seeded MSCs have been proposed as novel regenerative medicine devices.Even though methods to coat scaffolds with PL vary,in vitro studies suggest that PL allows for MSC adhesion,migration and differentiation inside these scaffolds.Increased new bone formation and vascularisation in comparison to uncoated scaffolds have also been observed in vivo.This review outlines the state-of-the-art research in the field of PL for ex vivo MSC expansion and in vivo bone regeneration.To minimise inconsistency between the studies,further work is required towards standardisation of PL preparation in terms of the starting material,platelet concentration,leukocyte depletion,and the method of platelet lysis.PL quality control procedures and its 'potency' assessment are urgently needed,which could include measurements of key growth and attachment factors important for MSC maintenance and differentiation.Furthermore,different PL formulations could be tailor-made for specific bone repair indications.Such measures would undoubtedly speed up clinical translation of PL-based treatments for bone regeneration. | Ala Altaie Heather Owston Elena Jones | 2016 | World Journal of Stem Cells2016，8，2： | 6 |
| 6 | STRUCTURE AND PHYSICAL PROPERTIES OF SUBMICROCRYSTALLINE METALS PREPARED BY SEVERE PLASTIC DEFORMATION显示文摘The results of investigations of structure and physical properties of submicrocrystalline (SMC) metals are presented. The SMC structure was formed by severe plastic deformation.The structure was investi- gated by calorimetric and mossbauer measurements and TEW stuidies. The behavior of physical proper- ties of SMC metals were analysed taking into account spectific features of their structure. | R. R. Mulyukov and M. D. Starostenkov( 1) Institute for Metals Superplasticity Problems of Russian Academy of Sciences, Khalturina 39, Ufa 450001, Russia 2)Altai State Technical University) | 2000 | Acta Metallurgica Sinica(English Letters)2000，13，1： | 5 |
| 7 | Predisposing factors and surgical outcome of complicated liver hydatid cysts显示文摘AIM: To evaluate the predisposing factors for peritoneal perforation and intrabiliary rupture and the effects of these complications on surgical outcome in liver hydatid disease.METHODS: A total of 372 patients with liver hydatid cysts who had undergone surgical treatment were evaluated retrospectively. Twenty eight patients with peritoneal perforation, 93 patients with spontaneous intrabiliary perforation, and 251 patients with noncomplicated hydatid cysts were treated in our clinics.RESULTS: When the predisposing factors for complications were evaluated, younger age, superf icial position, and larger cyst dimensions (P < 0.05; range, 0.0010.017) increased peritoneal perforation rates. It was shown that older age increased cyst dimensions, and presence of multiple and bilobar cysts increased intrabiliary rupture rates (P < 0.05; range, 0.0010.028). Partial pericystectomy and drainage was the most frequent surgical procedure in all groups (71.6%). The incidence of postoperative complications in the peritoneal perforated group, in the intrabiliary ruptured group, and in the noncomplicated group was 25%, 16.1% and 5.5%, respectively. When compared, complication rates were significantly different (P = 0.002). When length of hospital stay was compared, there was no signif icant difference between the groups (P > 0.05). The overall recurrence rate was 3.8% (14 patients), but there was not any statistical difference among the patient groups (P = 0.13). The early postoperative mortality rate was 1.1%. CONCLUSION: In peritoneally perforated and intrabiliary ruptured cases, the most important steps are irrigation of the peritoneal cavity and clearance of the cystic material from the biliary tree. | Alper Akcan Erdogan Sozuer Hizir Akyildiz Zeki Yilmaz Ahmet Ozturk Altay Atalay | 2010 | World Journal of Gastroenterology2010，16，24： | 4 |
| 8 | High adiponectin levels fail to protect against the risk of hypertension and,in women,against coronary disease:involvement in autoimmunity?显示文摘AIM:To investigate whether serum adiponectin protects against cardiometabolic risk in a population sample with prevailing metabolic syndrome.METHODS:Middle-aged adults representative of a general population with baseline circulating adiponectin measurements(n=1224)were analyzed prospectively at a mean of 3.8 years’follow-up,using continuous values or sex-specific tertiles.Total adiponectin was assayed by an ELISA kit.Type-2 diabetes was identified by criteria of the American Diabetes Association.Hypertension was defined as a blood pressure≥140 mmHg and/or≥90 mmHg and/or use of antihypertensive medication.Outcomes were predicted using Cox proportional hazards regression analysis in models that were controlled for potential confounders.RESULTS:In models of multiple linear regression,sex hormone-binding globulin,fasting insulin(inverse)and,in men,age were significant independent covariates of serum adiponectin which further tended in women to be positively associated with serum creatinine.Cox regression analyses for incident coronary heart disease(CHD),adjusted for sex,age,non-HDL cholesterol,waist circumference and C-reactive protein,revealed significant inverse association with adiponectin tertiles in men but not women(HR=0.66;95%CI:0.32-1.38 for highest tertile).Cox regression for type-2 diabetes in a similar model(wherein glucose replaced non-HDL cholesterol),adiponectin tertiles appeared to protect in each gender.HR for incident hypertension roughly displayed unity in each of the adiponectin tertiles(P-trend=0.67).CONCLUSION:High adiponectin levels failed to protect against the development of hypertension and,in women,against CHD,presumably paralleling impairment in renal function as well.Involvement of adiponectin in autoimmune complex with loss of antioxidative-antiatherogenic properties may be underlying. | Altan Onat Mesut Aydln Günay Can Bayram Kroglu Ahmet Karagz Servet Altay | 2013 | World Journal of Diabetes2013，4，5： | 3 |
| 9 | Photoselective Potassium Titanyl Phosphate (KTP) Laser Vaporization Versus Transurethral Resection of the Prostate for Prostates Larger Than 70 mL: A Short-Term Prospective Randomized Trial显示文摘 | Kaya Horasanli Mesrur Selcuk Silay Bulent Altay Orhan Tanriverdi Kemal Sarica Cengiz Miroglu | 2008 | Urology2008，，2： | 3 |
| 10 | Serum levels of hepatoprotective peptide adiponectin in non-alcoholic fatty liver disease显示文摘 | Cem Aygun Omer Senturk Saadettin Hulagu Suleyman Uraz Altay Celebi Tolga Konduk Birsen Mutlu Zeynep Canturk | 2006 | European Journal of Gastroenterology & Hepatology2006，，2： | 2 |
| 11 | Toward simple,generalizable neural networks with universal training for low-SWaP hybrid vision显示文摘Speed,generalizability,and robustness are fundamental issues for building lightweight computational cameras.Here we demonstrate generalizable image reconstruction with the simplest of hybrid machine vision systems:linear optical preprocessors combined with no-hidden-layer,'small-brain' neural networks. Surprisingly,such simple neural networks are capable of learning the image reconstruction from a range of coded diffraction patterns using two masks. We investigate the possibility of generalized or 'universal training' with these small brains. Neural networks trained with sinusoidal or random patterns uniformly distribute errors around a reconstructed image,whereas models trained with a combination of sharp and curved shapes (the phase pattern of optical vortices) reconstruct edges more boldly. We illustrate variable convergence of these simple neural networks and relate learnability of an image to its singular value decomposition entropy of the image. We also provide heuristic experimental results. With thresholding,we achieve robust reconstruction of various disjoint datasets. Our work is favorable for future real-time low size,weight,and power hybrid vision:we reconstruct images on a 15 W laptop CPU with 15,000 frames per second:faster by a factor of 3 than previously reported results and 3 orders of magnitude faster than convolutional neural networks. | BAURZHAN MUMINOV ALTAI PERRY RAKIB HYDER M.SALMAN ASIF LUAT T.VUONG | 2021 | Photonics Research2021，9，7： | 2 |
| 12 | Prediction of wear loss quantities of ferro-alloy coating using different machine learning algorithms显示文摘In this study,experimental wear losses under different loads and sliding distances of AISI 1020 steel surfaces coated with(wt.%)50FeCrC‐20FeW‐30FeB and 70FeCrC‐30FeB powder mixtures by plasma transfer arc welding were determined.The dataset comprised 99 different wear amount measurements obtained experimentally in the laboratory.The linear regression(LR),support vector machine(SVM),and Gaussian process regression(GPR)algorithms are used for predicting wear quantities.A success rate of 0.93 was obtained from the LR algorithm and 0.96 from the SVM and GPR algorithms. | Osman ALTAY Turan GURGENC Mustafa ULAS Cihan OZEL | 2020 | Friction2020，8，1： | 2 |
| 13 | A new approach for prediction of the wear loss of PTA surface coatings using artificial neural network and basic,kernel-based,and weighted extreme learning machine显示文摘Wear tests are essential in the design of parts intended to work in environments that subject a part to high wear.Wear tests involve high cost and lengthy experiments,and require special test equipment.The use of machine learning algorithms for wear loss quantity predictions is a potentially effective means to eliminate the disadvantages of experimental methods such as cost,labor,and time.In this study,wear loss data of AISI 1020 steel coated by using a plasma transfer arc welding(PTAW)method with FeCrC,FeW,and FeB powders mixed in different ratios were obtained experimentally by some of the researchers in our group.The mechanical properties of the coating layers were detected by microhardness measurements and dry sliding wear tests.The wear tests were performed at three different loads(19.62,39.24,and 58.86 N)over a sliding distance of 900 m.In this study,models have been developed by using four different machine learning algorithms(an artificial neural network(ANN),extreme learning machine(ELM),kernel-based extreme learning machine(KELM),and weighted extreme learning machine(WELM))on the data set obtained from the wear test experiments.The R2 value was calculated as 0.9729 in the model designed with WELM,which obtained the best performance among the models evaluated. | Mustafa ULAS Osman ALTAY Turan GURGENC Cihan OZEL | 2020 | Friction2020，8，6： | 2 |
| 14 | A review on protein–phenolic interactions and associated changes显示文摘 | Tugba Ozdal Esra Capanoglu Filiz Altay | 2013 | Food Research International2013，，2： | 2 |
| 15 | Influence of drying temperature, water content, and heating rate on gelatinization of corn starches显示文摘 | Altay F Gunasekaran S | 2006 | J Agric Food Chem2006，54，： | 1 |
| 16 | A retrospective study of dentoalveolar injuries of children in Ankara,Turkey显示文摘 | Altay N Gungor HC | 2001 | Dent Traumatol2001，17，5： | 1 |
| 17 | Relation of serum parathyroid hormone level to severity of heart failure显示文摘 | Altay H Zorlu A Binid S | 2012 | An: J Cardiol2012，109，2： | 1 |
| 18 | Patellar denervation in total knee arthroplasty without patellar resurfacing:a prospective,randomized controlled study显示文摘 | Altay MA Erturk C Altay N | 2012 | Orthop Traumatol Surg Res2012，98，4： | 1 |
| 19 | Molecular detection of Theileria and Babesia infections in cattle 显示文摘 | Altay K Aktas M | 2008 | Veterinary Parasitology2008，158，4： | 1 |
| 20 | The role of activated carbon asa catalyst in GAC/iron oxide/H2O2 oxidation process显示文摘 | Bach Altai Semiat Raphael | 2011 | Desalination2011，273，1： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员