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| 1 | Circulating extracellular RNAs,myocardial remodeling,and heart failure in patients with acute coronary syndrome显示文摘Background:Given high on-treatment mortality in heart failure(HF),identifying molecular pathways that underlie adverse cardiac remodeling may offer novel biomarkers and therapeutic avenues.Circulating extracellular RNAs(ex-RNAs)regulate important biological processes and are emerging as biomarkers of disease,but less is known about their role in the acute setting,particularly in the setting of HF.Methods:We examined the ex-RNA profiles of 296 acute coronary syndrome(ACS)survivors enrolled in the Transitions,Risks,and Actions in Coronary Events Center for Outcomes Research and Education Cohort.We measured 374 ex-RNAs selected a priori,based on previous findings from a large population study.We employed a two-step,mechanism-driven approach to identify ex-RNAs associated with echocardiographic phenotypes(left ventricular[LV]ejection fraction,LV mass,LV end-diastolic volume,left atrial[LA]dimension,and LA volume index)then tested relations of these ex-RNAs with prevalent HF(N=31,10.5%).We performed further bioinformatics analysis of microRNA(miRNAs)predicted targets’genes ontology categories and molecular pathways.Results:We identified 44 ex-RNAs associated with at least one echocardiographic phenotype associated with HF.Of these 44 exRNAs,miR-29-3p,miR-584-5p,and miR-1247-5p were also associated with prevalent HF.The three microRNAs were implicated in the regulation p53 and transforming growth factor-βsignaling pathways and predicted to be involved in cardiac fibrosis and cell death;miRNA predicted targets were enriched in gene ontology categories including several involving the extracellular matrix and cellular differentiation.Conclusions:Among ACS survivors,we observed that miR-29-3p,miR-584-5p,and miR-1247-5p were associated with both echocardiographic markers of cardiac remodeling and prevalent HF.Relevance for Patients:miR-29c-3p,miR-584-5p,and miR-1247-5p were associated with echocardiographic phenotypes and prevalent HF and are potential biomarkers for adverse cardiac remodeling in HF. | Khanh-Van Tran Kahraman Tanriverdi Gerard P.Aurigemma Darleen Lessard Mayank Sardana Matthew Parker Amir Shaikh Matthew Gottbrecht Zachary Milstone Selim Tanriverdi Olga Vitseva John F.Keaney Catarina I.Kiefe David D.McManus Jane E.Freedman | 2019 | Journal of Clinical & Translational Research2019,5,1: | 7 |
| 2 | Photoselective Potassium Titanyl Phosphate (KTP) Laser Vaporization Versus Transurethral Resection of the Prostate for Prostates Larger Than 70 mL: A Short-Term Prospective Randomized Trial显示文摘 | Kaya Horasanli Mesrur Selcuk Silay Bulent Altay Orhan Tanriverdi Kemal Sarica Cengiz Miroglu | 2008 | Urology2008,,2: | 3 |
| 3 | Associations between Vaspin Levels and Coronary Artery Disease显示文摘The relationship between serum vaspin levels and metabolic or coronary artery disease is currently of interest for researchers.Although adipokine concentrations have been shown to be increased signifi cantly in atherosclerotic lesions,the role adipokines in the atherosclerotic process remains to be elucidated.Vaspin is a new biological marker associated with obesity and impaired insulin sensitivity.Plasma vaspin concentration has been shown to correlate with the severity of coronary artery disease.Vascular infl ammation triggered by vaspin inhibits atherogenesis by suppressing macrophage foam cell formation and vascular smooth muscle cell migration and proliferation.Vaspin also contributes to plaque stabilization by increasing collagen content and reducing the intraplaque macrophage to vascular smooth muscle cell ratio.The therapeutic goal concerning vaspin is to fi ght atherosclerosis and related diseases,as well as to maintain vascular health. | Lutfu Askin Okan Tanriverdi Hakan Tibilli Serdar Turkmen | 2020 | Cardiovascular Innovations and Applications2020,,1: | 3 |
| 4 | Effect of transcatheter aortic valve replacement on P-wave duration, P-wave dispersion and left atrial size显示文摘BackgroundP 波浪分散(PWD ) , atrial 倔强的异质的一项措施,被定义为最大、最小的 P 波浪持续时间之间的差别。在有严重大动脉的狭窄的病人(作为) , P 波浪持续时间和 PWD 被显示被增加,显示 atrial 电的改变。然而, transcatheter 的效果 P 波浪形态学上的大动脉的阀门代替(TAVR ) 还没被建立。学习是与二估计 TAVR 的短、长期的效果的这的目的与左 atrial ( LA )联合在P波浪持续时间和 PWD 上 bioprosthetic 阀门打字 size.MethodsFifty --二( 36 女性)经历了在6月01日之间的 transfemoral TAVR 的在湾穴节奏的合格病人, 2012 并且有也的2014年7月31日 Medtronic CoreValve ( MCV )( n = 32 )或一个爱德华兹智慧 XT 阀门( n = 20 )被注册。标准 12 铅心电图和 echocardiographic 评估 pre-procedurally 被执行, post-TAVR 白天一和 6 月 post-TAVR。P 波浪持续时间和 PWD 被测量,有 echocardiographic 变量的关联分析是 performed.ResultsP 波浪持续时间, PWD 显著地在 post-TAVR 白天一上被减少(P <0.05 ) 。他们继续在六个月后续时期期间减少,但是不与短期的价值显著地不同(P >0.05 ) 。LA 直径的减少被发现重要在后续第六月(P <0.05 ) 。这些变化从植入的 bioprosthetic 阀门的类型是独立的(P >0.05 ) 。积极关联在 post-TAVR 白天一点在最小的 P 波浪持续时间和最大的大动脉的阀门坡度之间被检测(r = 0.297, P = 0.032 ).ConclusionsP 波浪持续时间和 PWD 显著地在显示早反向的 atrial 的 TAVR 以后早被减少电的改变。而且,中庭的结构的反向的改变被检测在后续 6 月。改变的 atrial 上的 bioprosthetic 阀门的二种类型的效果是类似的。 | Huseyin Dursun Zulkif Tanriverdi Tugce Colluoglu Dayimi Kaya | 2015 | Journal of Geriatric Cardiology2015,12,6: | 2 |
| 5 | Detection and genotyping of oocysts of Cryptosporidium parvum by real-time PCR and melting curve analysis显示文摘 | Tanriverdi S Tanyeli A Baslamisli F | 2002 | J Clin Microbiol2002,40,9: | 1 |
| 6 | Comparison of the effects of sevoflurane and isoflurane on myocardial protection in coronary bypass surgery-Original Investigation 显示文摘 | Ceyhan D Tanriverdi B Bilir A | 2011 | Anadolu Kardiyol Derg2011,11,3: | 1 |
| 7 | Information Technology Relatedness, Knowledge Management Capability, and Performance of Multibusiness Firms显示文摘 | Tanriverdi H | 2005 | MIS Quarterly2005,29,2: | 1 |
| 8 | The role of the blood transcfiptome in innate inflammation and stroke 显示文摘 | Freedman JE Vitseva O Tanriverdi K | 2010 | Ann N Y Acad Sci2010,1207,: | 1 |
| 9 | High risk of hypopituitarism after traumatic brain injury: a prospec- tive investigation of anterior pituitary function in the acute phase and 12 months after trauma显示文摘 | Tanriverdi F Senyurek H Unluhizarci K | 2006 | J Clin Endo- erinol Metab2006,91,6: | 1 |
| 10 | Information Technology Relatedness, Knowledge Management Capability, and Performance of Multibusiness Firms 显示文摘 | Tanriverdi H | 2005 | MIS Quarterly2005,,2: | 1 |
| 11 | Interaction of plasma homocysteine and thyroid hormone concentrations in the pathogenesis of the slow coronary flow phenomenon显示文摘 | Evrengul H Tanriverdi H Enli Y | | 0,,03: | 1 |
| 12 | Effect of obstructive sleep apnea on aortic elastic parameters-relationship to left ventricular mass and function显示文摘 | Tanriverdi H Evrengul H Kaftan A | 2006 | Circ J2006,70,: | 1 |
| 13 | Singles stage Fowler-stephens orchiopexy: a preferred alternative in the treatment of nonpalpable testes 显示文摘 | Horasanli K Mirogl C Tanriverdi O | 2006 | Pediatric Surg Internat2006,22,9: | 1 |
| 14 | Expression and cellular of mul- tidrug resistance-related proteins with focal cortical dyspla- sia显示文摘 | Ak H Ay B Tanriverdi T | 2007 | Seizure2007,16,6: | 1 |
| 15 | Knowledge Relatedness and the Performance of Mutibusiness Firms 显示文摘 | Huseyin Tanriverdi N Venkatraman | 2005 | Strategic Management Journal2005,,26: | 1 |
| 16 | Single stage Fower- Stephens orehidopexy: a preferred alternative in the treatment of nonpalpable tests显示文摘 | Horasanli K Miroglu C Tanriverdi O | 2006 | Pediatr Surg Int2006,22,9: | 1 |
| 17 | Early sign of athe- rescleresis in slow coronary flow and relationship with angiotensin- converting enzyme I/D polymorphism 显示文摘 | Tanriverdi H Evrengul H Mergen H | 2007 | Heart Vessels2007,22,1: | 1 |
| 18 | The potential role of BMI, plasma leptin, nesfatin - 1 and ghrelin levels in the early detection of pancreatic necrosis and severe acute panereatitis: a prospective cohort study 显示文摘 | TORKOGLU A BOYUK A TANRIVERDI MH | 2014 | Int J Surg2014,12,12: | 1 |
| 19 | Bronchoalveolar lavage fluid characteristics of patients with sarcoidosis and nonsarcoidosis interstitial lung diseases:ten-year experience of a single center in Turkey显示文摘 | Tanriverdi H Erboy F Altinsoy B | 2015 | Iran Red Crescent Med J2015,17,31: | 1 |
| 20 | Evolving traumatic brain lesions:predictors and results of ninety-eight head-injured patients显示文摘 | Sanus GZ Tanriverdi T Alver I | 2004 | Neurosurg Q2004,14,2: | 1 |