4篇
您的检索式：作者名="Altaf Hashmi"
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| 1 | High-dose-rate intraluminal brachytherapy during preoperative chemoradiation for locally advanced rectal cancers显示文摘AIM:To determine the feasibility and safety of high dose rate intraluminal brachytherapy(HDR-ILBT) boost during preoperative chemoradiation for rectal cancer.METHODS:Between 2008 and 2009,thirty-six patients with locally advanced rectal cancer(≥ T3 or N+),were treated initially with concurrent capecitabine(825 mg/m2 oral twice daily) and pelvic external beam radiotherapy(EBRT)(45 Gy in 25 fractions),then were randomized to group A;HDR-ILBT group(n = 17) to receive 5.5-7 Gy×2 to gross tumor volume(GTV) and group B;EBRT group(n = 19) to receive 5.4 Gy×3 fractions to GTV with EBRT.All patients underwent total mesorectal excision.RESULTS:Grade 3 acute toxicities were registered in 12 patients(70.6%) in group A and in 8(42.1%) in group B.Complete pathologic response of T stage(ypT0) in group A was registered in 10 patients(58.8%) and in group B,3 patients(15.8%) had ypT0(P < 0.0001).Sphincter preservation was reported in 6/9 patients(66.7%) in group A and in 5/10 patients(50%) in group B(P < 0.01).Overall radiological response was 68.15% and 66.04% in Group A and B,respectively.During a median follow up of 18 mo,late grade 1 and 2 sequelae were registered in 3 patients(17.6%) and 4 patients(21.1%) in the groups A and B,respectively.CONCLUSION:HDR-ILBT was found to be effective dose escalation technique in preoperative chemoradiation for rectal cancers,with higher response rates,downstaging and with manageable acute toxicities. | Mutahir Ali Tunio Mansoor Rafi Altaf Hashmi Rehan Mohsin Abdul Qayyum Mujahid Hasan Amjad Sattar Muhammad Mubarak | 2010 | World Journal of Gastroenterology2010，16，35： | 3 |
| 2 | Degradation of malathion by Pseudomonas during activated sludge treatment system using principal component analysis (PCA)显示文摘Popular descriptive multivariate statistical method currently employed is the principal component analyses (PCA) method. PCA is used to develop linear combinations that successively maximize the total variance of a sample where th ere is no known group structure. This study aimed at demonstrating the performan ce evaluation of pilot activated sludge treatment system by inoculating a strain of Pseudomonas capable of degrading malathion which was isolated by enrichment technique. An intensive analytical program was followed for evaluating the effic iency of biosimulator by maintaining the dissolved oxygen (DO) concentration at 4.0 mg/L. Analyses by high performance liquid chromatographic technique revealed that 90% of malathion removal was achieved within 29 h of treatment whereas COD got reduced considerably during the treatment process and mean removal efficien cy was found to be 78%. The mean pH values increased gradually during the treatm ent process ranging from 7.36—8.54. Similarly the mean ammonia-nitrogen (NH3-N) values were found to be fluctuating between 19.425—28.488 mg/L, mean nitrite-n itrogen (NO3-N) ranging between 1.301—2.940 mg/L and mean nitrate-nitrogen (NO3 -N) ranging between 0.0071—0.0711 mg/L. The study revealed that inoculation of bacterial culture under laboratory conditions could be used in bioremediation of environmental pollution caused by xenobiotics. The PCA analyses showed that pH, COD, organic load and total malathion concentration were highly correlated and emerged as the variables controlling the first component, whereas dissolved oxyg en, NO3-N and NH3-N governed the second component. The third component repeated the trend exhibited by the first two components. | Hashmi Imran Khan M Altaf Kim Jong-Guk | 2006 | Journal of Environmental Sciences2006，18，4： | 3 |
| 3 | Whole-Pelvis or Bladder-Only Chemoradiation for Lymph Node–Negative Invasive Bladder Cancer: Single-Institution Experience显示文摘 | Mutahir A. Tunio Altaf Hashmi Abdul Qayyum Rehan Mohsin Ahmed Zaeem | 2012 | International Journal of Radiation Oncology Biology Physics2012，，3： | 1 |
| 4 | Neoadjuvant Chemotherapy for Transitional Cell Carcinoma of the Bladder: A Single Centre Experience显示文摘 | Gauhar Sultan Babar Malik Syed Najeeb Niamatullah Altaf Hashmi Asad Shehzad Mubarak M SyedAdeeb ul Hassan Rizvi | 2016 | Journal of Life Sciences2016，10，2： | 0 |
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