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| 1 | Thiazolidinedione treatment inhibits bile duct proliferation and fibrosis in a rat model of chronic cholestasis显示文摘AIM: To investigate the effects of troglitazone (TGZ), an anti-diabetic drug which activates peroxisome proliferatoractivated receptor-γ (PPAR-γ), for liver tissue repair, and the development of ductular reaction, following common bile duct ligation (BDL) in rats.METHODS: Rats were supplemented with TGZ (0.2% w/w in the pelleted food) for 1 wk before BDL or sham operation.Animals were killed at 1, 2, or 4 wk after surgery.RESULTS: The development of liver fibrosis was reduced in rats receiving TGZ, as indicated by significant decreases of procollagen type Ⅰ gene expression and liver hydroxyproline levels. Accumulation of α-smooth-muscle actin (SMA)-expressing cells surrounding newly formed bile ducts following BDL, as well as total hepatic levels of SMA were partially inhibited by TGZ treatment, indicating the presence of a reduced number and/or activation of hepatic stellate cells (HSC) and myofibroblasts. Development of the ductular reaction was inhibited by TGZ, as indicated by histochemical evaluation and hepatic activity of γ-glutamyltransferase (GGT).CONCLUSION: Treatment with thiazolidinedione reduces ductular proliferation and fibrosis in a model of chronic cholestasis, and suggests that limiting cholangiocyte proliferation may contribute to the lower development of scarring in this system. | Fabio Marra Raffaella DeFranco Gaia Robino Erica Novo Eva Efsen Sabrina Pastacaldi Elena Zamara Alessandro Vercelli Benedetta Lottini Carlo Spirli Mario Strazzabosco Massimo Pinzani Maurizio Parola | 2005 | World Journal of Gastroenterology2005，11，32： | 9 |
| 2 | Contrast-enhanced ultrasonography and spiral computed tomography in the detection and characterization of portal vein thrombosis complicating hepatocellular carcinoma显示文摘 | Sandro Rossi Giorgia Ghittoni Valentina Ravetta Francesca Torello Viera Laura Rosa Martina Serassi Mara Scabini Alessandro Vercelli Carmine Tinelli Barbara Dal Bello Peter N. Burns Fabrizio Calliada | 2008 | European Radiology2008，，8： | 2 |
| 3 | Contrast-enhanced ultrasonography and spiral computed tomography in the detection and characterization of portal vein thrombosis complicating hepatocellular carcinoma显示文摘 | Sandro Rossi Giorgia Ghittoni Valentina Ravetta Francesca Torello Viera Laura Rosa Martina Serassi Mara Scabini Alessandro Vercelli Carmine Tinelli Barbara Dal Bello Peter N. Burns Fabrizio Calliada | 2008 | European Radiology2008，，8： | 1 |
| 4 | Structural Financial Instability and Cyclical Fluctuations显示文摘 | Alessandro Vercelli | 2000 | Structural Change and Economic Dynamics2000，，11： | 1 |
| 5 | Financial Fragility and Economic Fluctuations显示文摘 | Serena Sordi Alessandro Vercelli | 1996 | Journal of Economic Behavior & Organization1996，61，4： | 1 |
| 6 | Contrast-enhanced ultrasonography and spiral computed tomography in the detection and characterization of portal vein thrombosis complicating hepatocellular carcinoma显示文摘 | Sandro Rossi Giorgia Ghittoni Valentina Ravetta Francesca Torello Viera Laura Rosa Martina Serassi Mara Scabini Alessandro Vercelli Carmine Tinelli Barbara Dal Bello Peter N. Burns Fabrizio Calliada | 2008 | European Radiology2008，，8： | 1 |
| 7 | Structural Financial Instability and Cyclical Fluctuations显示文摘 | Alessandro Vercelli | 2000 | Structural Change and Economic Dynamics2000，，11： | 1 |
| 8 | Macrophage stimulating protein is a novel neurotrophic factor显示文摘 | Maria Cristina Stella Alessandro Vercelli Mariaelena Repici | 2001 | Mol Biol Cell2001，12，： | 1 |
| 9 | Modulation of neuronal stem cell differentiation by hypoxia and reactive oxygen species显示文摘 | Helena L.A. Vieira Paula M. Alves Alessandro Vercelli | 2011 | Progress in Neurobiology2011，，3： | 1 |
| 10 | Radiofrequency Ablation of Pancreatic Neuroendocrine Tumors: A Pilot Study of Feasibility, Efficacy, and Safety显示文摘 | Sandro Rossi Francesca Torello Viera Giorgia Ghittoni Lorenzo Cobianchi Laura Lavinia Rosa Luisa Siciliani Chandra Bortolotto Letizia Veronese Alessandro Vercelli Anna Gallotti Valentina Ravetta | 2014 | Pancreas2014，，6： | 1 |
| 11 | Mesenchymal Stem Cell Transplantation Reduces Glial Cyst and Improves Functional Outcome After Spinal Cord Compression显示文摘 | Marina Boido Diego Garbossa Marco Fontanella Alessandro Ducati Alessandro Vercelli | 2012 | World Neurosurgery2012，，： | 1 |
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