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| 1 | Thiazolidinedione treatment inhibits bile duct proliferation and fibrosis in a rat model of chronic cholestasis显示文摘AIM: To investigate the effects of troglitazone (TGZ), an anti-diabetic drug which activates peroxisome proliferatoractivated receptor-γ (PPAR-γ), for liver tissue repair, and the development of ductular reaction, following common bile duct ligation (BDL) in rats.METHODS: Rats were supplemented with TGZ (0.2% w/w in the pelleted food) for 1 wk before BDL or sham operation.Animals were killed at 1, 2, or 4 wk after surgery.RESULTS: The development of liver fibrosis was reduced in rats receiving TGZ, as indicated by significant decreases of procollagen type Ⅰ gene expression and liver hydroxyproline levels. Accumulation of α-smooth-muscle actin (SMA)-expressing cells surrounding newly formed bile ducts following BDL, as well as total hepatic levels of SMA were partially inhibited by TGZ treatment, indicating the presence of a reduced number and/or activation of hepatic stellate cells (HSC) and myofibroblasts. Development of the ductular reaction was inhibited by TGZ, as indicated by histochemical evaluation and hepatic activity of γ-glutamyltransferase (GGT).CONCLUSION: Treatment with thiazolidinedione reduces ductular proliferation and fibrosis in a model of chronic cholestasis, and suggests that limiting cholangiocyte proliferation may contribute to the lower development of scarring in this system. | Fabio Marra Raffaella DeFranco Gaia Robino Erica Novo Eva Efsen Sabrina Pastacaldi Elena Zamara Alessandro Vercelli Benedetta Lottini Carlo Spirli Mario Strazzabosco Massimo Pinzani Maurizio Parola | 2005 | World Journal of Gastroenterology2005，11，32： | 9 |
| 2 | Profunda femoris artery pseudoaneurysm following revision for femoral shaft fracture nonunion显示文摘Femoral artery pseudoaneurysms(FAPs) have been described following internal fixation of intertrocantheric, subtrocantheric and intracapsular femoral neck fractures as well as core decompression of the femoral head. The diagnosis of FAP is usually delayed because of non-specific clinical features like pain, haematoma,swelling, occasional fever and unexplained anaemia.Because of the insidious onset and of the possible delayed presentation of pseudoaneurysms, orthopaedic and trauma surgeons should be aware of this complication. We report a case of Profunda Femoris arterial branch pseudoaneurysm, diagnosed in a 40-year-old male 4 wk after revision with Kuntscher intramedullary nail of a femoral shaft nonunion. The diagnosis was achieved by computed tomography angiography and the lesion was effectively managed by endovascular repair. The specific literature and suggestions for treatment are discussed in the paper. | Federico Valli Marco GA Teli Marco Innocenti Ruggero Vercelli Domenico Prestamburgo | 2013 | World Journal of Orthopedics2013，4，3： | 3 |
| 3 | Contrast-enhanced ultrasonography and spiral computed tomography in the detection and characterization of portal vein thrombosis complicating hepatocellular carcinoma显示文摘 | Sandro Rossi Giorgia Ghittoni Valentina Ravetta Francesca Torello Viera Laura Rosa Martina Serassi Mara Scabini Alessandro Vercelli Carmine Tinelli Barbara Dal Bello Peter N. Burns Fabrizio Calliada | 2008 | European Radiology2008，，8： | 2 |
| 4 | Algorithms for acoustic localization based on microphone array in service robotics显示文摘 | Mumolo Enzo Nolich Massiniliano Vercelli Gianni | 2003 | Robotics and Autonomous Systems2003，42，2： | 1 |
| 5 | Genetics and biology of asthma 2010:La,ci darem la mano显示文摘 | Vercelli D | 2010 | Allergy clin Immunology2010，125，2： | 1 |
| 6 | Contrast-enhanced ultrasonography and spiral computed tomography in the detection and characterization of portal vein thrombosis complicating hepatocellular carcinoma显示文摘 | Sandro Rossi Giorgia Ghittoni Valentina Ravetta Francesca Torello Viera Laura Rosa Martina Serassi Mara Scabini Alessandro Vercelli Carmine Tinelli Barbara Dal Bello Peter N. Burns Fabrizio Calliada | 2008 | European Radiology2008，，8： | 1 |
| 7 | Experimentally-induced microencephaly:effects on cortical neurons显示文摘 | GARBOSSA D VERCELLI A | 2003 | Brain Res Bull2003，60，4： | 1 |
| 8 | Serum uric acid levels predict new-onset type 2 diabetes in hospitalized patients with primary hypertension: the MAGIC study显示文摘 | Viazzi F Leoncini G Vercelli M | 2011 | Diabetes Care2011，34，1： | 1 |
| 9 | Asthma显示文摘 | Martinez FD Vercelli D | 2013 | Lancet2013，382，9901： | 1 |
| 10 | Synchornized development of production, inventory and distribution schedules 显示文摘 | Fumero F Vercellis C | 1999 | Transportation Science1999，33，3： | 1 |
| 11 | Asthma显示文摘 | Martinez FD Vercelli D | 2013 | Lancet2013，382，9901： | 1 |
| 12 | Gene-environment interactions in asthma and al lergy:the end of the beginning? 显示文摘 | Vercelli D | 2010 | Curr Opin Allergy Clin Immunol2010，10，2： | 1 |
| 13 | Discovering susceptibility genes for asthma and allergy 显示文摘 | Vercelli D | 2008 | Nat Rev Immunol2008，8，3： | 1 |
| 14 | Discovering susceptibility genes for asthma and allergy显示文摘 | Vercelli D | 2008 | Nat Rev Immunol2008，8，： | 1 |
| 15 | Synchronized development of production, inventory and distribution schedules显示文摘 | F FUMERO C VERCELLIS | 1999 | Transportation Sci- ence1999，33，3： | 1 |
| 16 | Serum uric acid levels predict new-onset type 2 diabetes in hospitalized patients with primary hypertention: the MAGIC study显示文摘 | Viazzi F Leoncini G Vercelli M | 2011 | Diabetes Care2011，34，1： | 1 |
| 17 | Serum uric acid levels predict new-onset type 2 diabetes in hospitalized patients with primary hypertension:the magic study显示文摘 | Viazzi F Leoncini G Vercelli M | 2011 | Diabetes Care2011，34，1： | 1 |
| 18 | Asthma显示文摘 | MARTINEZ F D VERCELLI D | 2013 | Lancet2013，382，9901： | 1 |
| 19 | Human mesenchymal stem cell transplantation extends survival, improves motor performance and decreases neuroinflammation in mouse model of amyotrophic lateral sclerosis显示文摘 | VERCELLI A MEREUTA OM GARBOSSA D | 2008 | Neurobiol Dis2008，31，3： | 1 |
| 20 | Structural Financial Instability and Cyclical Fluctuations显示文摘 | Alessandro Vercelli | 2000 | Structural Change and Economic Dynamics2000，，11： | 1 |
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