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| 1 | Predictors of mortality after transjugular portosystemic shunt显示文摘AIM:To investigate if echocardiographic and hemodynamic determinations obtained at the time of transjugular intrahepatic portosystemic shunt(TIPS)can provide prognostic information that will enhance risk stratification of patients.METHODS:We reviewed medical records of 467 patients who underwent TIPS between July 2003 and December 2011 at our institution.We recorded information regarding patient demographics,underlying liver disease,indication for TIPS,baseline laboratory values,hemodynamic determinations at the time of TIPS,and echocardiographic measurements both before and after TIPS.We recorded patient comorbidities that may affect hemodynamic and echocardiographic determinations.We also calculated Model for Endstage Liver Disease(MELD)score and Child Turcotte Pugh(CTP)class.The following pre-and post-TIPS echocardiographic determinations were recorded:Left ventricular ejection fraction,right ventricular(RV)systolic pressure,subjective RV dilation,and subjective RV function.We recorded the following hemodynamic measurements:Right atrial(RA)pressure before and after TIPS,inferior vena cava pressure before and after TIPS,free hepatic vein pressure,portal vein pressure before and after TIPS,and hepatic venous pressure gradient(HVPG).RESULTS:We reviewed 418 patients with portal hypertension undergoing TIPS.RA pressure increased by a mean ± SD of 4.8 ± 3.9 mmH g(P < 0.001),HVPG decreased by 6.8 ± 3.5 mmH g(P < 0.001).In multivariate linear regression analysis,a higher MELD score,lower platelet count,splenectomy and a higher portal vein pressure were independent predictors of higher RA pressure(R = 0.55).Three variables predicted 3-mo mortality after TIPS in a multivariate analysis:Age,MELD score,and CTP grade C.Change in the RA pressure after TIPS predicted long-term mortality(per 1 mm Hg change,HR = 1.03,95%CI:1.01-1.06,P < 0.012).CONCLUSION:RA pressure increased immediately after TIPS particularly in patients with worse liver function,portal hypertension,emergent TIPS placement and history of splenectomy.The increase in RA pressure after TIPS was associated with increased mortality.Age,splenectomy,MELD score and CTP grade were independent predictors of long-term mortality after TIPS. | Mona Ascha Sami Abuqayyas Ibrahim Hanouneh Laith Alkukhun Mark Sands Raed A Dweik Adriano R Tonelli | 2016 | World Journal of Hepatology2016，8，11： | 13 |
| 2 | The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years显示文摘 | Mark R Nelson Christine Katlama Julio S Montaner David A Cooper Brian Gazzard Bonaventura Clotet Adriano Lazzarin Knud Schewe Joep Lange Christina Wyatt Sue Curtis Shan-Shan Chen Stephen Smith Norbert Bischofberger James F Rooney | 2007 | AIDS2007，，10： | 2 |
| 3 | Bioactive peptides in water-soluble extracts of ovine cheeses from Southern Brazil and Uruguay显示文摘 | Stela Maris Meister Meira Daniel Joner Daroit Virginia Etges Helfer Ana Paula Folmer Corrêa Jéferson Segalin Silvana Carro Adriano Brandelli | 2012 | Food Research International2012，，1： | 1 |
| 4 | Utilization and disposal of fly-ash and other coal residues in terrestrial ecosystems a review显示文摘 | ADRIANO D C PAGE A L ELSEEWI A A | 1980 | J Environ Qual1980，9，3： | 1 |
| 5 | Influence of zeolite, apatite and Fe-oxide on Cd and Pb uptake by crops显示文摘 | Chlopecka A Adriano D C | 1997 | The Science of Total Environment1997，207，23： | 1 |
| 6 | Using Pivots to Speed - Up K- Medoids Clustering显示文摘 | A P Adriano A N Mario T J Caetano | 2011 | Journal of Information and Data Man- agement2011，2，2： | 1 |
| 7 | Utilization and disposal of fly ash and other coal residues in terrestrial ecosystems: a review 显示文摘 | Adriano D C Page A L Elseewi A A Chang A C Straughan I | 1980 | J Environ Qual1980，9，3： | 1 |
| 8 | Cream cheese as a symbiotic food carrier using B ifidobacterium animalis B b‐12 and L actobacillus acidophilus L a‐5 and inulin显示文摘 | Larissa L Alves Neila S P S Richards Paula Mattanna Diego F Andrade Adriano P S Rezer Liana I G Milani Adriano G Cruz José A F Faria | 2012 | Int J Dairy Technol2012，，1： | 1 |
| 9 | Microwave-assisted synthesis of indole-derivatives via cycloisomerization of 2-alkynylanilines in water without added catalysts, acids, or bases 显示文摘 | Adriano Carpita a Arianna Ribecai | 2009 | Tetrahedron Letters2009，50，49： | 1 |
| 10 | Utilization and disposal of fly ash and other coal residues in terrestrial ecosystems: A review显示文摘 | Adriano D C Page A L Elseewi A A | 1980 | J Environ Qual1980，9，： | 1 |
| 11 | Multipointcovalent immobilization of microbial lipase on chitosan and agaroseactivated by different methods显示文摘 | RODRIGUES D S MENDES A A ADRIANO W S | 2008 | Journal of Molecular Catalysis B:Enzymatic2008，51，34： | 1 |
| 12 | Handing constraints as objectives in a multi-objective genetic based algorithm显示文摘 | Vieira D A G Adriano R L S Krahenbuhl L | 2002 | Journal of Microwaves and Optoelectronics2002，2，6： | 1 |
| 13 | Discovery of 1-(4-Fluorophenyl)-(3R)--(4S)-(4-hydrox-yphenyl)-2-azetidinone(SCH 58235):a designed,potent,orally active inhibitor of cholesterol absorption显示文摘 | Stuart B R Tram H Adriano A | 1998 | J Med Chem1998，41，6： | 1 |
| 14 | A water quality index applied to an international shared river basin:the case of the Douro River显示文摘 | ADRIANO A BORDALO RITA TEIXEIRA WILLIAM J WIEBE | 2006 | Environment Management2006，，38： | 1 |
| 15 | Chemical-- equilibria of selenium in soils--a theoretical development 显示文摘 | Elrashidi M A Adriano D C Workman S M | 1987 | Soil Science1987，144，2： | 1 |
| 16 | Detection of fun- gal contamination of cereal grain sample by an electronic nose显示文摘 | Roberto P Adriano A Eugenio M | 2006 | Sensors and Actuators B2006，119，： | 1 |
| 17 | 显示文摘 | Dors Gisanara Freitas Larissa Mendes Adriano A | 2012 | Energy and Fuels2012，269，： | 1 |
| 18 | Robust multi-objective team 22problem:a case study of uncertainties in design optimization显示文摘 | Soares G L Adriano R Maia C A | 2009 | IEEE Transactions on Magnetics2009，45，3： | 1 |
| 19 | 2H-1T Phase Transition and Hydrogen Evolution Activity of Mo S2,Mo Se2,WS2and WSe2Strongly Depends on the MX2Composition显示文摘 | Adriano A Zdenek S Martin P | 2015 | Chemical Communications2015，51，： | 1 |
| 20 | Influence of zeolite,apatite and Fe-oxide on cadmium and Pb uptake by crops显示文摘 | Chlopecka A Adriano D C 1997 | 1997 | Science Tpal Environment1997，207，： | 1 |
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