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| 1 | Predictors of mortality after transjugular portosystemic shunt显示文摘AIM:To investigate if echocardiographic and hemodynamic determinations obtained at the time of transjugular intrahepatic portosystemic shunt(TIPS)can provide prognostic information that will enhance risk stratification of patients.METHODS:We reviewed medical records of 467 patients who underwent TIPS between July 2003 and December 2011 at our institution.We recorded information regarding patient demographics,underlying liver disease,indication for TIPS,baseline laboratory values,hemodynamic determinations at the time of TIPS,and echocardiographic measurements both before and after TIPS.We recorded patient comorbidities that may affect hemodynamic and echocardiographic determinations.We also calculated Model for Endstage Liver Disease(MELD)score and Child Turcotte Pugh(CTP)class.The following pre-and post-TIPS echocardiographic determinations were recorded:Left ventricular ejection fraction,right ventricular(RV)systolic pressure,subjective RV dilation,and subjective RV function.We recorded the following hemodynamic measurements:Right atrial(RA)pressure before and after TIPS,inferior vena cava pressure before and after TIPS,free hepatic vein pressure,portal vein pressure before and after TIPS,and hepatic venous pressure gradient(HVPG).RESULTS:We reviewed 418 patients with portal hypertension undergoing TIPS.RA pressure increased by a mean ± SD of 4.8 ± 3.9 mmH g(P < 0.001),HVPG decreased by 6.8 ± 3.5 mmH g(P < 0.001).In multivariate linear regression analysis,a higher MELD score,lower platelet count,splenectomy and a higher portal vein pressure were independent predictors of higher RA pressure(R = 0.55).Three variables predicted 3-mo mortality after TIPS in a multivariate analysis:Age,MELD score,and CTP grade C.Change in the RA pressure after TIPS predicted long-term mortality(per 1 mm Hg change,HR = 1.03,95%CI:1.01-1.06,P < 0.012).CONCLUSION:RA pressure increased immediately after TIPS particularly in patients with worse liver function,portal hypertension,emergent TIPS placement and history of splenectomy.The increase in RA pressure after TIPS was associated with increased mortality.Age,splenectomy,MELD score and CTP grade were independent predictors of long-term mortality after TIPS. | Mona Ascha Sami Abuqayyas Ibrahim Hanouneh Laith Alkukhun Mark Sands Raed A Dweik Adriano R Tonelli | 2016 | World Journal of Hepatology2016，8，11： | 13 |
| 2 | Transcranial direct current stimulation in psychiatric disorders显示文摘The interest in non-invasive brain stimulation techniques is increasing in recent years. Among these techniques, transcranial direct current stimulation(t DCS) has been the subject of great interest among researchers because of its easiness to use, low cost, benign profile of side effects and encouraging results of research in the field. This interest has generated several studies and randomized clinical trials, particularly in psychiatry. In this review, we provide a summary of the development of the technique and its mechanism of action as well as a review of the methodological aspects of randomized clinical trials in psychiatry, including studies in affective disorders, schizophrenia, obsessive compulsive disorder, child psychiatry and substance use disorder. Finally,we provide an overview of t DCS use in cognitive enhancement as well as a discussion regarding its clinical use and regulatory and ethical issues. Although many promising results regarding t DCS efficacy were described, the total number of studies is still low, highlighting the need of further studies aiming to replicate these findings in larger samples as to provide a definite picture regarding t DCS efficacy in psychiatry. | Gabriel Tortella Roberta Casati Luana V M Aparicio Antonio Mantovani Natasha Senco Giordano D’Urso Jerome Brunelin Fabiana Guarienti Priscila Mara Lorencini Selingardi Débora Muszkat Bernardo de Sampaio Pereira Junior Leandro Valiengo Adriano H Moffa Marcel Simis Lucas Borrione André R Brunoni | 2015 | World Journal of Psychiatry2015，5，1： | 6 |
| 3 | The safety of tenofovir disoproxil fumarate for the treatment of HIV infection in adults: the first 4 years显示文摘 | Mark R Nelson Christine Katlama Julio S Montaner David A Cooper Brian Gazzard Bonaventura Clotet Adriano Lazzarin Knud Schewe Joep Lange Christina Wyatt Sue Curtis Shan-Shan Chen Stephen Smith Norbert Bischofberger James F Rooney | 2007 | AIDS2007，，10： | 2 |
| 4 | Collateral, risk management, and the distribution of debt capacity 显示文摘 | Adriano R Viswanathan S | 2010 | Journal of Finance2010，65，6： | 1 |
| 5 | Effects of organic amendments on the reduction and phytoavailability of chromate in mineral soil显示文摘 | Bolan N S Adriano D C Natesan R | 2003 | Journal of Environmental Quality2003，32，： | 1 |
| 6 | Effects of organic a-mendments on the reduction and phytoavailability of chromat- einmineral soil显示文摘 | Bolan N S Adriano D C Natesan R | 2003 | J Environ Qual2003，32，1： | 1 |
| 7 | Investigation of silica particle structure containing metallocene immobilized by a sol-gel method显示文摘 | Adriano G F Nilo S M C Argimiro R S | 2008 | Journalofnon-crystallinesolids2008，354，33： | 1 |
| 8 | Study of the susceptibility of the GSM-R communications face to the electromagnetic interferences of the rail environment 显示文摘 | DUDOYER S DENIAU V ADRIANO R R | 2012 | IEEE Transactions on Electromagnetic Compatibility2012，54，3： | 1 |
| 9 | Handing constraints as objectives in a multi-objective genetic based algorithm显示文摘 | Vieira D A G Adriano R L S Krahenbuhl L | 2002 | Journal of Microwaves and Optoelectronics2002，2，6： | 1 |
| 10 | Discovery of 1-(4-Fluorophenyl)-(3R)--(4S)-(4-hydrox-yphenyl)-2-azetidinone(SCH 58235):a designed,potent,orally active inhibitor of cholesterol absorption显示文摘 | Stuart B R Tram H Adriano A | 1998 | J Med Chem1998，41，6： | 1 |
| 11 | Mass transfer in olefin polymerization: estimative of macro and microscale diffusion coefficients through the swollen polymer 显示文摘 | Adriano G Fisch Joao H Z dos Santos Nilo S M Cardozo Argimiro R Secchi | 2008 | Chemical Engineering Science2008，63，： | 1 |
| 12 | Deficit irrigation based on drought tolerance and root signalling in potatoes and tomatoes 显示文摘 | Jensen Christian R Battilani Adriano Plauborg Finn | 2010 | Agricultural Water Management2010，98，3： | 1 |
| 13 | Robust multi-objective team 22problem:a case study of uncertainties in design optimization显示文摘 | Soares G L Adriano R Maia C A | 2009 | IEEE Transactions on Magnetics2009，45，3： | 1 |
| 14 | Capacity of adsorption of Pb2+and Ni2+from aqueous by chitosanproduced from silkworm chrysalides in different degrees of deacety-lation显示文摘 | Alexandre T Paulino Marcos R Guilherme Adriano V Reis | 2007 | Journal of Hazardous Materials2007，147，： | 1 |
| 15 | Deficit irrigation based on drought tolerance and root signaling in potatoes and tomatoes显示文摘 | JENSEN C R ADRIANO B FINN P | | 0，，03： | 1 |
| 16 | Dissolved organic matter: Biogeo- chemistry, dynamics, and environmental significance in soils显示文摘 | Bolan NS Adriano DC Kunhikrishnan A James T McDowell R Senesi N | 2009 | Advances in Agronomy2009，110，1314： | 1 |
| 17 | Synthesis and water absorption transport mechanism of a pH-sensitive polymer network structured on vinyl-functionalized pectin显示文摘 | Marcos R Guilherme Thais A Moia Adriano V Reis | 2009 | Biomacr0molecules2009，10，1： | 1 |
| 18 | Removal of methylene blue dye from an aqueous media using superabsorbent hydrogel supported on modified polysaccharide显示文摘 | Alexandre T Paulino Marcos R Guilherme Adriano V Reis | 2006 | J Colloid Interf Sci2006，301，1： | 1 |
| 19 | Effects of organic amendments on the reduction and phytoavailability of chromate in mineral soil 显示文摘 | BOLAN N S ADRIANO D C NATESAN R | 2003 | Journal of Environmental Quality2003，32，： | 1 |
| 20 | Deficit irrigation based on drought tolerance and root signaling in potatoes and tomatoes显示文摘 | Jensen C R Adriano B Finn P | 2010 | Agri- cultural Water Management2010，98，3： | 1 |
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