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| 1 | Hemodynamic and metabolic effects of terlipressin in patients with cirrhosis receiving a nonselectiveβ-blocker显示文摘 | Florence Vachiery MD Dr. Richard Moreau MD Dr. Adrian Gadano MD Song Yang MD Phillippe Sogni MD Antoine Hadengue MD Stephane Cailmail Thierry Soupison MD Didier Lebrec MD | 1996 | Digestive Diseases and Sciences1996，，9： | 1 |
| 2 | Epidemiology and Clinical Presentation of Hepatocellular Carcinoma显示文摘 | MD | 2002 | Di Bisceglie2002，13，9： | 1 |
| 3 | Serum activity of alanine aminotransferase (ALT) as an indicator of health and disease显示文摘 | Kim WR Steven LF Adrian MD | 2008 | Hepatology2008，47，4： | 1 |
| 4 | 超声定位与体表标志定位在儿童髂腹股沟-髂腹下神经阻滞中的比较:罗哌卡因血浆浓度测定的临床指导意义显示文摘背景儿童髂腹股沟-髂腹下神经阻滞常导致血浆局部麻醉药浓度过高。超声引导能为注射局麻药提供准确的解剖定位,从而影响局麻药的血浆浓度变化。为此,我们比较了超声定位与体表标志定位下行神经阻滞对罗哌卡因血浆浓度的影响。方法在全麻诱导下,将66例准备行腹股沟疝修补术的儿童随机分为两组,年龄为8个月-7岁,一组在超声定位下行髂腹股沟-髂腹下神经阻滞(n=35),另一组在体表标志定位下行髂腹股沟-髂腹下神经阻滞(n=31),均使用0.5%的罗哌卡因0.25ml/kg(1.25mg/kg),分别在给药后0、5、10、20、30分钟用高效液相色谱法测罗哌卡因的血浆浓度,观察最大血浆浓度(Cmax),达峰时间(tmax),吸收率常数(ka),在时间0分钟时血浆浓度的上升速度(dC0/d1)和曲线下面积值(AUC)。结果使用超声定位技术阻滞患儿的Cmax(sd)、ka、dC0/dt和AUC的值均高于使用标志定位技术的值,而tmax的值也短于使用标志定位技术的值。[Cmax:1.78(0.62)vs1.23(0.70)μg/ml,P〈0.01;ka:14.4(10.7)vs11.7(11.4)h^-1,P〈0.05;dC0/d1:0.26(0.12)vs0.15(0.03)μg·ml^-1·min^-1,P〈0.01;AUC:42.4(15.9)vs27.2(18.1)μg·30min^-1·ml^-1,P〈0.001;tmax:20.4(8.6)vs25.3(7.6)分钟,P〈0.05)。结论药物代谢动力学数据表明:与体表标志定位相比,在超声定位下行髂腹股沟-髂腹下神经阻滞局麻药的最大血浆浓度更高,药物吸收也更快。因此,在超声定位下行髂腹股沟-髂腹下神经阻滞时需要考虑减少局麻药的用量。 | Marion Weintraud, MD Marit Lundblad, MD Stephan C. Kettner, MD Harald Willschke, MD Stephan Kapral, MD Per-Arne Loennqvist, MD Karl Koppatz Klaus Turnheim, MD Adrian Boesenberg, MD Peter Marhofer, MD 周洁(译) 李士通(校) | 2012 | 麻醉与镇痛2012，8，3： | 1 |
| 5 | Incorporation of sparingly soluble species in mesostructured surfactant - polymer films 显示文摘 | BENJAMIN MD O'DRISCOLL ADRIAN M HAWLEY KAREN J EDLER | 2008 | Journal of Colloid and Interface Science2008，317，2： | 1 |
| 6 | High-pressure liquid chromatographic determination of 13-cis-retinoic acid and all-trans-retinoic acid in human plasma显示文摘 | Chandrasekhar S Adrian MD | 1978 | Anal Biochem1978，86，： | 1 |
| 7 | 《麻醉与镇痛》中文版的十年之路显示文摘大约10年前,已故的KCWong教授向国际麻醉研究学会(IARS)提议创办《麻醉与镇痛》杂志中文版,以便使中国的麻醉学界同仁能够更便捷地了解IARS教育性出版物中的相关内容。中文版杂志的内容选自《麻醉与镇痛》杂志以及IARS年会中的专题讲座。该提议获得了IARS的热情支持,KCWong教授和AWGelb教授受IARS常委理事会的委托,负责指导中文版杂志的创编工作。 | Adrian W. Gelb, MD 阮侠(译) | 2008 | 麻醉与镇痛2008，4，3： | 1 |
| 8 | Differential effects of estrogen and raloxifene on messenger RNA and matrix metalloproteinase 2 activity in the rat uterus 显示文摘 | Helvering LM Adrian MD Geiser AG | 2005 | Biol Reprod2005，72，4： | 1 |
| 9 | Historical review of lymphatic mapping in gastrointestinal malignancies显示文摘 | Sukamal Saha MD FACS FRCS(C) Adrian G. Dan MD Anton J. Bilchik MD PhD Yuko Kitagawa MD Elie Schochet MD Sharan Choudhri MD Lucille T. Saha MD MPH David Wiese MD PhD Donald Morton MD Masaki Kitajima MD | 2004 | Annals of Surgical Oncology2004，，3： | 1 |
| 10 | Differential effects of estrogen and raloxifene on messenger RNA and matrix metalloproteinase 2 activity in the rat uterus显示文摘 | Helvering LM Adrian MD Geiser AG | 2005 | Biol Reprod2005，72，4： | 1 |
| 11 | Modulation of Glucose Metabolism Inhibits Hypoxie Accumu- lation of Hypoxia-lndueible Factor-1 cL (HIF-1 α )显示文摘 | ADRIAN STAAB MD JURGEN LOFFLER HARUN M SAID | 2007 | Strahlenther- apie und Onkologie2007，183，7： | 1 |
| 12 | Incorporation of sparingly solublespecies in structured surfactant-polymer films 显示文摘 | BENJAMIN MD 0 DRISCOLL ADRIAN M HAWLEY KARENJEDLER | 2008 | Journal of Colloid and Interface Science2008，317，2： | 1 |
| 13 | Photochemical synthesis of N-arylben zophenanthridine selective estrogen receptor modulators(SERMs) 显示文摘 | Grese TA Adrian MD Phillips DL | 2001 | J Med Chem2001，44，17： | 1 |
| 14 | Free radical scavengers prevent reflux esophagitis in rats显示文摘 | Dr. Gerold J. Wetscher MD Paul R. Hinder Debasis Bagchi PhD Galen Perdikis MD Elizabeth J. Redmond MD Dr. Karl Glaser MD Thomas E. Adrian PhD Dr. Ronald A. Hinder MD PhD | 1995 | Digestive Diseases and Sciences1995，，6： | 1 |
| 15 | Esophagitis in sprague-dawley rats is mediated by free radicals显示文摘 | Gerold J. Wetscher MD Galen Perdikis MD David H. Kretchmar PhD Ronald G. Stinson MD Debasis Bagchi PhD Elizabeth J. Redmond FRCS Thomas E. Adrian PhD Dr. Ronald A. Hinder MD PhD FACS | 1995 | Digestive Diseases and Sciences1995，，6： | 1 |
| 16 | Treatment Failure After Percutaneous Radiofrequency Ablation for Nonsurgical Candidates With Pulmonary Metastases From Colorectal Carcinoma显示文摘 | Tristan D. Yan BSc (Med) MBBS Julie King MPH Adrian Sjarif BSc (Med) MBBS Derek Glenn MBBS Karin Steinke MD Ahmed Al-Kindy MD David L. Morris MD PhD | 2007 | Annals of Surgical Oncology2007，，5： | 1 |
| 17 | 过度通气4小时对控制式脑皮质撞击损伤大鼠的神经认知行为和病损大小的远期影响显示文摘背景局部创伤性脑损伤大鼠过度通气4小时对其神经认知行为、运动功能、协调能力和病损大小的远期影响。方法对大鼠进行为期14天的神经认知行为学训练,包括孔板实验、木梁行走实验、木梁平衡实验。21只SD大鼠(369±15g),氟烷麻醉后气管插管,机械通气,行控制性皮质撞击损伤(深1.75mm,直径5mm,速度4m/s)。将大鼠随机分入正常通气组(n=10;Paco2=38-42mmHg)和过度通气组(n=11;Paco2=28-32mmHg),机械通气4小时。创伤后持续检测大鼠的行为学和运动能h20天。随后,将大鼠在深麻醉下断头取脑,冰冻脑组织,切片,评估病损大小。结果过度通气组与正常通气组相比外显记忆受损严重。两组大鼠在损伤初期的运动功能和协调能力的测试(木梁行走和木梁平衡实验)中表现均有欠缺,过度通气组更为严重。但是,在实验结束时,两组并无明显差异。创伤后第20天,过度通气组大鼠测得的病损大小(69.7±13.0mm^3)明显大于正常通气组(48.3±15.6mm^3)。结论创伤性脑损伤后过度通气4/1,时(Paco2=28-32mmHg)虽然增加了组织学损伤,但并没有对大鼠远期的神经认知功能造成不良影响。 | Eva Eberspacher, DVM, DACVA Manfred Blobner, MD Christian Werner, MD Stefanie Ruf, DVM Barbara Eckel, MD Kristin Engelhard, MD Wolfgang Schmahl, DW Adrian W. Gelb, MBChB, FRCP 邓希锦(译) | 2012 | 麻醉与镇痛2012，8，1： | 0 |
| 18 | Guidelines from an expert panel for the management of diabetic macular edema in the Malaysian population显示文摘AIM:To derive a Malaysia guideline and consensus as part of the Malaysia Retina Group's efforts for diagnosis,treatment,and best practices of diabetic macular edema(DME).The experts'panel suggests that the treatment algorithm to be divided into groups according to involvement the central macula.The purpose of DME therapy is to improve edema and achieve the best visual results with the least amount of treatment load.METHODS:On two different occasions,a panel of 14 retinal specialists from Malaysia,together with an external expert,responded to a questionnaire on management of DME.A consensus was sought by voting after compiling,analyzing and discussion on first-phase replies on the round table discussion.A recommendation was deemed to have attained consensus when 12 out of the 14 panellists(85%)agreed with it.RESULTS:The terms target response,adequate response,nonresponse,and inadequate response were developed when the DME patients'treatment responses were first characterized.The panelists reached agreement on a number of DME treatment-related issues,including the need to classify patients prior to treatment,firstline treatment options,the right time to switch between treatment modalities,and side effects associated with steroids.From this agreement,recommendations were derived and a treatment algorithm was created.CONCLUSION:A detail and comprehensive treatment algorithm by Malaysia Retina Group for the Malaysian population provides guidance for treatment allocation of patients with DME. | Nor Fariza Ngah Nor Asiah Muhamad Shelina Oli Mohamed Roslin Azni Abdul Aziz Nur Hasnah Ma’amor Nor Azita Ahmad Tarmidzi Hanizasurana Hashim Hamisah Ishak Wan Norliza Wan Muda Rosiah Muda Azian Adnan Rafidah Md Saleh Wong Hon Seng Nurfahzura Mohd Jamil Tara Mary George Adrian Koh | 2023 | International Journal of Ophthalmology(English edition)2023，16，5： | 0 |
| 19 | Intraspecific variation in shoot flammability in Dracophyllum rosmarinifolium is not predicted by habitat environmental conditions显示文摘Background:Flammability is a compound plant trait that can vary significantly across natural populations within species.Investigating intraspecific variation in flammability provides insights into the evolution of plant flam-mability and inform understanding of wildfire risk and behaviour in different habitats.Methods:We measured four flammability variables,representing ignitibility(time to ignition),sustainability(total burning time),combustibility(maximum temperature during burning)and consumability(percentage of biomass consumed by fire)to assess the shoot-level flammability of Dracophyllum rosmarinifolium(G.Forst.)(Ericaceae),a polymorphic endemic species distributed throughout New Zealand.We examined the relationship between flammability components and a suite of climatic and geographic variables(elevation,latitude,mean annual temperature(MAT),mean annual rainfall(MAR)of the sample locations,etc.).Results:We measured shoot-level flammability components of 62 individuals across eight populations.Burning time,maximum temperature and burnt biomass were positively correlated with each other,while ignition score was independent of other flammability components.All flammability components varied significantly across the eight populations.The habitat conditions we considered were not related to any of the shoot-level flammability components of D.rosmarinifolium.Conclusions:Intraspecific variation in flammability in D.rosmarinifolium may be a byproduct of selection on other functional traits,such as leaf size,shoot lipid content,indicating that plant flammability is an incidental result,rather than selected for,at least in ecosystems without fire as a selective force. | Xinglei Cui Adrian M.Paterson George LW.Perry Sarah V.Wyse Md Azharul Alam Congde Huang Shixing Zhou Lin Xiao Changhong Lai Fang He Dongyu Cao Kate Marshall Timothy J.Curran | 2022 | Forest Ecosystems2022，9，2： | 0 |
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