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| 1 | Intrahepatic biliary cystic neoplasms:Surgical results of 9 patients and literature review显示文摘AIM: To investigate the eligible management of the cystic neplasms of the liver. METHODS: The charts of 9 patients who underwent surgery for intrahepatic biliary cystic liver neoplasms between 2003 and 2008 were reviewed retrospectively. Informed consent was obtained from the patients and approval was obtained from the designated review board of the institution. RESULTS: All patients were female with a median (range) age of 49 (27-60 years). The most frequent symptom was abdominal pain in 6 of the patients. Four patients had undergone previous laparotomy (with other diagnoses) which resulted in incomplete surgery or recurrences. Liver resection (n = 6) or enucleation (n = 3) was performed. The final diagnosis was intrahepaticbiliary cystadenoma in 8 patients and cystadenocarcinoma in 1 patient. All symptoms resolved after surgery. There has been no recurrence during a median (range) 31 (7-72) mo of follow up. CONCLUSION: In spite of the improvement in imaging modalities and increasing recognition of biliary cystadenoma and cystadenocarcinoma, accurate preoperative diagnosis may be difficult. Complete surgical removal (liver resection or enucleation) of these lesions yields satisfying long-term results. | Ali Emre Kür■at Rahmi Serin Ilgin zden Yaman Tekant Orhan Bilge Ayd■n Alper Mine Güllüoglu Koray Güven | 2011 | World Journal of Gastroenterology2011，17，3： | 15 |
| 2 | Nigella sativa relieves the deleterious effects of ischemia reperfusion injury on liver显示文摘AIM: To determine whether Nigella sativa prevents hepatic ischemia-reperfusion injury to the liver. METHODS: Thirty rats were divided into three groups as sham (Group 1), control (Group 2), and Nigella sati-va (NS) treatment group (Group 3). All rats underwent hepatic ischemia for 45 min followed by 60 min period of reperfusion. Rats were intraperitoneally infused with only 0.9% saline solution in group 2. Rats in group 3 received NS (0.2 mL/kg) intraperitoneally, before isch-emia and before reperfusion. Blood samples and liver tissues were harvested from the rats, and then the rats were sacrifi ced. Serum aspartate aminotransfera-se (AST), alanine aminotransferase (ALT), and lactate dehydrogenase (LDH) levels were determined. Total antioxidant capacity (TAC), catalase (CAT), total oxida-tive status (TOS), oxidative stress index (OSI) and my-eloperoxidase (MPO) in hepatic tissue were measured. Also liver tissue histopathology was evaluated by light microscopy. RESULTS: The levels of liver enzymes in group 3 weresignifi cantly lower than those in the group 2. TAC in liver tissue was significantly higher in group 3 than in group 2. TOS, OSI and MPO in hepatic tissue were signifi cantly lower in group 3 than the group 2. Histo-logical tissue damage was milder in the NS treatment group than that in the control group. CONCLUSION: Our results suggest that Nigella sa-tiva treatment protects the rat liver against to hepatic ischemia-reperfusion injury. | Fahrettin Yildiz Sacit Coban Alpaslan Terzi Mustafa Ates Nurten Aksoy Hale Cakir Ali Riza Ocak Muharrem Bitiren | 2008 | World Journal of Gastroenterology2008，14，33： | 8 |
| 3 | In vitro effect of pantoprazole on lower esophageal sphincter tone in rats显示文摘AIM:To investigate the in vitro effects of pantoprazole on rat lower esophageal sphincter(LES)tone.METHODS:Rats weighing 250-300 g,provided by the Yeditepe University Experimental Research Center(Yü-DETAM),were used throughout the study.They were anesthetized before decapitation.LES tissues whose mucosal lining were removed were placed in a stan-dard 30-mL organ bath with a modif ied Krebs solution and continuously aerated with 95% oxygen-5% carbon dioxide gas mixture and kept at room temperature.The tissues were allowed to stabilize for 60 min.Sub-sequently,the contractile response to 10-6 mol/L carba-chol was obtained.Different concentrations of freshly prepared pantoprazole were added directly to the tis-sue bath to generate cumulative concentrations of 5×10-6 mol/L,5×10-5 mol/L,and 1.5×10-4 mol/L.Activi-ties were recorded on an online computer via a 4-channeltransducer data acquisition system using the software BSL PRO v 3.7,which also analyzed the data.RESULTS:Pantoprazole at 5×10-6 mol/L caused a small,but statistically insignif icant,relaxation in the car-bachol-contracted LES(2.23% vs 3.95%).The 5×10-5 mol/L concentration,however,caused a signif icant relax-ation of 10.47% compared with the control.1.5×10-4 mol/L concentration of pantoprazol caused a 19.89% relaxation in the carbachol contracted LES(P<0.001).CONCLUSION:This is the fi rst study to demonstrate that pantoprazole has a relaxing effect in isolated LESs.These results might have signif icant clinical implications for the subset of patients using proton pump inhibitors who do not receive full symptomatic alleviation from gastroesophageal reflux disease. | Mustafa Duman Mahmut zer Enver Rean Yeliz Demirci Ali E Atιcι Tahsin Dalgι Erdal B Bostancι Ece Gen | 2011 | World Journal of Gastroenterology2011，17，46： | 3 |
| 4 | Penile length and somatometric parameters: a study in healthy young Turkish men显示文摘这研究的目的是决定平均阴茎长度并且在一组年轻、健康的土耳其语的人调查在阴茎长度和 somatometric 参数之间的关系。1132 个人的一个总数在学习被包括。这些题目的年龄,高度和重量被记录。阴茎长度处于松驰、拉长的状态被测量。在阴茎长度和 somatometric 参数之间的关联被分析。这些题目的吝啬的年龄是 20.3 卤 0 .9 年。处于松驰、拉长的状态的吝啬的阴茎长度是 9.3 卤 1 .3 和 13.7 卤 1 .6 厘米,分别地(P < 0.001 ) 。在松驰、拉长的阴茎长度之间有积极关联(r=0.800, P < 0.001 ) 。吝啬的阴囊的体积是 22.0 卤 2 .8 cm3。弱积极关联在阴茎长度和吝啬的阴囊的体积之间被检测(为松驰的阴茎长度的 r=0.143 和为拉长的阴茎长度的 r=0.140, P < 0.001 为两个) 。同样,弱积极关联在阴茎长度之间被发现(松驰、拉长) 并且高度,重量和身体团索引,分别地(P < 0.001,为所有) 。这些结果证明 somatometric 参数与阴茎长度被相关。我们相信进一步的研究将关于原因的关系提供更多的信息。 | Yllmaz Asian Ali Atan Ali Oemur Aydm Varol Nalcacloglu Altug Tuncel Ates Kadloglu | 2011 | Asian Journal of Andrology2011，13，2： | 3 |
| 5 | Laparoscopic right-sided colonic resection with transluminal colonoscopic specimen extraction显示文摘AIM: To study the transcolonic extraction of the proximally resected colonic specimens by colonoscopic assistance at laparoscopic colonic surgery. METHODS: The diagnoses of our patients were Crohn's disease, carcinoid of appendix and adenocarcinoma of cecum. We preferred laparoscopic total mesocolic resections. Colon and terminal ileum were divided with endoscopic staplers. A colonoscope was placed per anal and moved proximally in the colon till to reach the colonic closed end under the laparoscopic guidance. The stump of the colon was opened with laparoscopic scissors. A snare of colonoscope was released and the intraperitoneal complete free colonic specimen was grasped. Specimen was moved in to the colon with the help of the laparoscopic graspers and pulled gently through the large bowel and extracted through the anus. The open end of the colon was closed again and the ileal limb and the colon were anastomosed intracorporeally with a 60-mm laparoscopic stapler. The common enterotomy orifice was closed in two layers with a running intracorporeal suture.RESULTS: There were three patients with laparoscopic right-sided colonic resections and their specimens were intended to remove through the remnant colon by colonoscopy but the procedure failed in one patient(adenocarcinoma) due to a bulky mass and the specimen extraction was converted to transvaginal route. All the patients had prior abdominal surgeries and had related adhesions. The operating times were 210, 300 and 500 min. The lengths of the specimenswere 13, 17 and 27 cm. In our cases, there were no superficial or deep surgical site infections or any other complications. The patients were discharged uneventfully within 4-5 d and they were asymptomatic after a mean 7.6 mo follow-up(ranged 4-12). As far as we know, there were only 12 cases reported yet on transcolonic extraction of the proximal colonic specimens by colonoscopic assistance after laparoscopic resections. With our cases, success rate of the overall experience in the literature was 80%(12/15) in selected cases. CONCLUSION: Transcolonic specimen extraction for right-sided colonic resection is feasible in selected patients. Both natural orifice surgery and intracorporeal anastomosis avoids mini-laparotomy for specimen extraction or anastomosis. | Cuneyt Kayaalp Koray Kutluturk Mehmet Ali Yagci Mustafa Ates | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，12： | 3 |
| 6 | What is the relationship between frailty and orthostatic hypotension in older adults?显示文摘Background Frailty and orthostatic hypotension (OH),which is common in older adults,is associated with morbidity and mortality.The relationship between them remains unclear.The aim of the study is to determine whether there is a relationship between frailty and OH.Methods A total of 496 patients who were admitted to the geriatric clinic and underwent comprehensive geriatric assessment were retrospectively reviewed.In a cross-sectional and observational study,OH was measured by the Head-up Tilt Table test at 1,3,and 5 min (respectively,OH1,OH3,and OH5) and the frailty was measured by the Fried’s frailty scale.Results The mean age of all patients was 75.4 ± 7.38.The prevalence of females was 69.8%.When the frail people were compared with the pre-frail and the robust ones,the frailty was associated with OH1.There was no relationship between the groups in terms of OH1 when the pre-frail group was compared with the robust group.OH3 were higher in the frail group than in the pre-frail group (P < 0.05) and the OH5 were higher in the frail group than in the pre-frail and robust group (P < 0.05),but OH3 and OH5 were not associated with frailty status when they were adjusted for age (P > 0.05).Slowness and weakness were associated with OH1 (P < 0.05),whereas the other components of the Fried’s test were not.Conclusions Frailty may be a risk factor for OH1.The 1^st min measurements of OH should be routinely evaluated in frail older adults to prevent OH-related poor outcomes. | Suleyman Emre Kocyigit Pinar Soysal Esra Ates Bulut Ali Ekrem Aydin Ozge Dokuzlar Ahmet Turan Isik | 2019 | Journal of Geriatric Cardiology2019，16，3： | 3 |
| 7 | Reticulated platelet levels in patients with ulcerative colitis显示文摘 | Hasan Kayahan Mesut Akarsu Mehmet Ali Ozcan Serdal Demir Halil Ates Belkis Unsal Hale Akpinar | 2007 | International Journal of Colorectal Disease2007，，12： | 2 |
| 8 | A multicentre study of Shigella diarrhoea in six Asian countries:disease burden, clinical manifestations, and microbiology 显示文摘 | Seidlein L Kim DR Ali M at el | | Plos Med0，3，： | 1 |
| 9 | mTOR-dependent abnormalities in autophagy characterize human malformations of cortical development: evidence from focal cortical dysplasia and tuberous sclerosis 显示文摘 | Yasin SA Ali AM Tata M et at | 2013 | Acta Neuropathol2013，126，2： | 1 |
| 10 | Risk factors for endometrial cancer显示文摘 | Ali AT | 2013 | Ceska Gynekol2013，78，5： | 1 |
| 11 | Role of GABA-A receptor in the preoptic area in the regulation of sleep-wakefulness and rapid eye movement sleep 显示文摘 | ALI M JHA S K KAUR S et at | 1999 | Neurosci Res1999，33，3： | 1 |
| 12 | Ectopic pituitary adenoma presenting as midline nasopharyngeal mass 显示文摘 | Ali R Noma U Jansen M et at | 2010 | Ir J Med Sci2010，179，4： | 1 |
| 13 | Arterial reconstruction of infected femoral artery pseudoaneurysms using superficial femoral popliteal vein? 显示文摘 | Bell CL Ali AT BrawleyJG | 2005 | J Am Coll Surg2005，200，6： | 1 |
| 14 | Alkaloids from Veratrum album显示文摘 | Rahman AT Ali RT Parveen T | 1991 | Phytochemistry1991，30，1： | 1 |
| 15 | A “silent” course of normotensive scleroderma renal crisis: case report and review of the literature显示文摘 | Hadim Akoglu Gokhan Kadir At?lgan Ramazan Ozturk Ezgi Coskun Yenigun Ipek Is?k Gonul Ali R?za Odabas | 2009 | Rheumatology International2009，，10： | 1 |
| 16 | Asthmaan obesity: does weight loss improve asthma control? A systematic review 显示文摘 | Juel CT Ali Z Nilas L et at | 2012 | Journal of Asthma andAJlergy2012，5，： | 1 |
| 17 | Emerging role of endovascular grafts in complex aortoiliac occlusive disease显示文摘 | Ali AT Modrall JG Lopez J | 2003 | J Vasc Surg2003，38，3： | 1 |
| 18 | Arterial reconstruction of infected femoral artery pseudoaneuryms using supemdal fernoral-popliteal vein显示文摘 | Bell cL Ali AT Brawley JG | 2005 | J Am coll surg2005，200，6： | 1 |
| 19 | Arterial reconstruction of infected femoral artery pseudoaneurysms using superficial femoral梡opliteal vein显示文摘 | Bell CL Ali AT Brawley JG | 2005 | J Am Coll Surg2005，200，6： | 1 |
| 20 | Esophageal stent erosion into the common carotid artery 显示文摘 | ALI AT KOKOSKA MS ERDEM E | 2007 | Vasc Endovascular Surg2007，41，1： | 1 |
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