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| 1 | Evaluation of CA125 and NT-proBNP values in patients undergoing transcatheter aortic valve implantation显示文摘BackgroundTranscatheter 大动脉的阀门培植(TAVI ) 是在通过手术高的风险,或不能实行的病人的最低限度地侵略的、新兴的治疗。为风险分类使用的参数在病人的选择有一些缺乏。学习是在糖类抗原 125 上评估 TAVI 的影响的这的目的(CA125 ) 和 N 终端职业人员大脑类型 Natriuretic 肽(NT-proBNP ) 作为在最近的年里经常被使用了的 biomarkers,并且也到 prognosis.Methods & 的这些 biomarkers 的关系;ResultsTranscatheter 大动脉的阀门培植在这研究在 31 个病人上被练习。然后,在病人学习在以前并且在 TAVI 以后的 CA125 和 NT-proBNP 层次被评估。病人也根据他们的左室的喷射部分(LVEF ) 被组织, CA125 铺平(LVEF ≥40% 并且 <40% ;CA125 ≤35 U/L 和 >35 U/L ) 。TAVI 手术成功地在所有病人被动。没有在里面医院死亡,在功能的能力的实质的改进在跟帖被检测。另外,统计上重要的减少在所有病人的 post-TAVI CA125 和 NT-proBNP 层次被检测(CA125 83.8 ±18.1 U/L 对 64.3 ±14.2 U/L, P = 0.008;NT-proBNP:4633.6 ±627.6 pg/mL 对 2866.3 ±536.8 pg/mL, P <0.001 ) 。在根据 CA125 层次划分的组,也在 CA125 层次有统计上重要的 post-TAVI 衰落。在 CA125 > 以内;35 U/L 和 LVEF <40% 组,对一个心律调整器的永久需要在(3.2%) 被要求病人和死亡在二被观察(6.4%) 在 TAVI 在以后的病人跟随 TAVI 能与 CA125 和 NT-proBNP 的高基线层次在病人有效地并且可靠地被执行的 up.ConclusionsThe 结果表演。当高 biomarker 层次与不希望得到的事件被联系时,这些 biomarkers 与 TAVI 实质地被减少,并且当然,这些 biomarkers 能为 TAVI 在耐心的选择被用于风险分类。 | Huseyin Ayhan Haca Ahmet Kasapkara Tahir Durmaz Telat Keles Cenk San Serdal Bastug Kemal Esref Erdogan Nihal Akar Bayram Emine Bilen Murat Akgay Engin Bozkurt | 2015 | Journal of Geriatric Cardiology2015，12，2： | 5 |
| 2 | Reticulated platelet levels in patients with ulcerative colitis显示文摘 | Hasan Kayahan Mesut Akarsu Mehmet Ali Ozcan Serdal Demir Halil Ates Belkis Unsal Hale Akpinar | 2007 | International Journal of Colorectal Disease2007，，12： | 2 |
| 3 | Characteristic features of 20 patients with Sheehan's syndrome显示文摘 | Hatice SD Fatih K Serdal K | 2006 | Gvnecological Endocrinblogy2006，22，5： | 1 |
| 4 | A W-band MMIC radar system for remote detection of vital signs 显示文摘 | Sebastian D Serdal A Steffen S | 2012 | Journal of In- flared Millimeter and Terahertz Waves2012，33，12： | 1 |
| 5 | A Chryseobacterium meningosepticum outbreak in a neonatal ward显示文摘 | Serdal Gungor | 2003 | infection control and hospital epidemiology2003，24，8： | 1 |
| 6 | Solution of porous media equation by Adomian decomposition method显示文摘 | Serdal P | 2005 | PhysicsLetters2005，34，4： | 1 |
| 7 | Neonatal adrenal hemorrhage as a complication of trau-matic vaginal delivery: diagnosis and follow-up with uhrasonogra- phy 显示文摘 | Ilke Mungan Akln Yilmaz Tabel Serdal Gungor | 2008 | Journal of Inonu University Medical F-aculty2008，15，2： | 1 |
| 8 | Characteristic features of 20 patients with Sheehan’s syndrome显示文摘 | Hatice Sebila Dö kmeta&scedil Fatih Kilicli Serdal Korkmaz Ozlem Yonem | 2006 | Gynecological Endocrinology2006，，5： | 1 |
| 9 | Dental and alveolar arch widths in normal occlusion,class Ⅱ division1 and class Ⅱdivision 2显示文摘 | Tancan U Badel M Serdal U | 2005 | Angle Orthod2005，75，6： | 1 |
| 10 | Performance analysis of a two stage pad cooling system in broiler houses, Turk显示文摘 | Metin PETEK Serdal D? KMEN Mehmet Must'afa O? AN | 2012 | J Vet Anita Sci2012，36，1： | 1 |
| 11 | Role of Mean Platelet Volume in Diagnosis of Childhood Acute Appendicitis显示文摘 | Bunyamin Uyanik Cemil Kavalci Engin Deniz Arslan Fevzi Yilmaz Ozgur Aslan Serdal Dede Fatih Bakir Isa Kilicaslan | 2012 | Emergency Medicine International2012，，： | 1 |
| 12 | Evaluation of andesite waste as mineral filler in asphaltic concrete mixture 显示文摘 | Uzun Ismail Terzi Serdal | 2012 | Construction and Building Materials2012，，31： | 1 |
| 13 | The growth factor receptor HER- 2/neu and EGFR, their relationship, the effect on the prognosis in early stage epithelial ovarian carcinoma显示文摘 | Skirnisdottir I Sorbe B Serdal T | 2001 | Int J Gynecol Cancer2001，11，： | 1 |
| 14 | Backealeulation of Pavement Layer Parameters Using Artificial Neural Network 显示文摘 | Mehmet Saltan and Serdal Ter'zi | 2004 | Indian Journal of Engineering and Materials Sciences2004，，： | 1 |
| 15 | Mushroom poison- ing: retrospective analysisi of 294 cases 显示文摘 | EREN SH DEMIREL Y SERDAL U | | Clinics(Sao Paulo)0，65，5： | 1 |
| 16 | Mushroom poisoning:retrospec- tive analysis of 294 cases 显示文摘 | Eren SH Demirel Y Serdal U | 2010 | Clinics ( Sao Paulo)2010，65，5： | 1 |
| 17 | Hormone receptor status of primary tumor as a prognostic factor in patients with liver metastases from breast cancer treated with transcatheter arterial chemoembolization显示文摘TO THE EDITOR We read with great interest the article by XP et al. They reported the results of their experience with transcatheter arterial chemoembolization (TACE) and systemic chemotherapy for forty-five patients with liver metastases from breast cancer and evaluate the prognostic factors. In their study, the response and survival rates were significantly better in TACE group than in chemotherapy group. The lymph node status of the primary cancer, the clinical stage of liver metastases, the Child-Pugh grade, loss of weight were found to be significandy associated with survival in both univariate and multivariate and analyses. | Kadri Altundag Ozden Altundag Serdal Aktolga Ozlem Yavas Cem Boruban | 2005 | World Journal of Gastroenterology2005，11，44： | 0 |
| 18 | 在试验性的糖尿病的 3 个层次建模的网膜的 VEGF, TNF,和 caspase 上的 intravitreal bevacizumab 和 intravitreal fasudil 的效果的比较显示文摘AIM: To evaluate the influence of an intravitreal injection of bevacizumab and fasudil on the retinal vascular endothelial growth factor(VEGF),tumor necrosis factor alpha(TNFα),and caspase 3 levels in a diabetic rabbit model. · METHODS: The study included 6 healthy rabbits(Group 1),6 rabbits with experimentally induced diabetes mellitus(DM)(Group 2),7 rabbits with experimentally induced DM to which intravitreal bevacizumab was administered(Group 3),and 7 rabbits with experimentally induced DM to which intravitreal fasudil was administered(Group 4). An intravitreal injection of 1.25mg/50μL bevacizumab in the right eye of rabbits in Group 3 and an intravitreal injection of 0.0064mg/50μL fasudil in the right eye of rabbits in Group 4 were administered on day 21 after the induction of DM. The studied eyes of the rabbits were enucleated three days after the intravitreal injection. The TNFα,VEGF,and caspase 3 levels were determined using the ELISA method. · RESULTS: There was a statistically significant difference in the VEGF and caspase 3 levels between groups(P =0.005 and P =0.013,respectively),but the TNF α level did not differ significantly between groups(P = 0.792). It was found that VEGF levels were significantly lower in Group 1 and Group 3 than in Group 2 using the Mann-Whitney U test with the Bonferroni correction(P = 0.004 for both comparison). There was no statistically significant difference between other groups with regard to VEGF levels(the P value ranged between 0.015 and 0.886). Although the P values of the caspase 3 levels were 0.015 for Group 1 and Group 4,0.038 for Group 2and Group 3,and 0.018 for Group 3 and Group 4,these P values remained above the threshold P value of 0.0083,which was the statistically significant level for post hoc tests. ·CONCLUSION: An intravitreal injection of bevacizumab decreased both the VEGF level,which plays a role in angiogenesis,and the caspase 3 level,which plays a role in apoptosis. Although not as effective as bevacizumab,fasudil had a beneficial effect on the VEGF levels but significantly increased the caspase 3 levels. | Fatih Celik Fatih Ulas Zeynep Gunes Ozunal Tulin Firat Serdal Celebi Umit Dogan | 2014 | International Journal of Ophthalmology(English edition)2014，7，1： | 0 |
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