|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Diabetic nephropathy:Is it time yet for routine kidney biopsy?显示文摘Diabetic nephropathy(DN)is one of the most important long-term complications of diabetes.Patients with diabetes and chronic kidney disease have an increased risk of all-cause mortality,cardiovascular mortality,and kidney failure.The clinical diagnosis of DN depends on the detection of microalbuminuria.This usually occurs after the first five years from the onset of diabetes,and predictors of DN development and progression are being studied but are not yet implemented into clinical practice.Diagnostic tests are useful tools to recognize onset,progression and response to therapeutic interventions.Microalbuminuria is an indicator of DN,and it is considered the only noninvasive marker of early onset.However,up to now there is no diagnostic tool that can predict which patients will develop DN before any damage is present.Pathological renal injury is hard to predict only with clinical and laboratory findings.An accurate estimate of damage in DN can only be achieved by the histological analysis of tissue samples.At the present time,renal biopsy is indicated on patients with diabetes under the suspicion of the presence of nephropathies other than DN.Results from renal biopsies in patients with diabetes had made possible the classification of renal biopsies in three major groups associated with different prognostic features:diabetic nephropathy,non-diabetic renal disease(NDRD),and a superimposed non-diabetic condition on underlying diabetic nephropathy.In patients with type 2 diabetes with a higher degree of suspicion for NDRD,it is granted the need of a renal biopsy.It is important to identify and differentiate these pathologies at an early stage in order to prevent progression and potential complications.Therefore,a more extensive use of biopsy is advisable. | Maria L Gonzalez Suarez David B Thomas Laura Barisoni Alessia Fornoni | 2013 | World Journal of Diabetes2013，4，6： | 29 |
| 2 | Psychopathological aspects of kidney transplantation: Efficacy of a multidisciplinary team显示文摘Renal transplantation is a well established treatment for end-stage renal disease, allowing most patients to return to a satisfactory quality of life. Studies have identified many problems that may affect adaptation to the transplanted condition and postoperative compliance. The psychological implications of transplantation have important consequences even on strictly physical aspects. Organ transplantation is very challenging for the patient and acts as an intense stressor stimulus to which the patient reacts with neurotransmitter and endocrine-metabolic changes. Transplantation can result in a psychosomatic crisis that requires the patient to mobilize all bio-psychosocial resources during the process of adaptation to the new foreign organ which may result in an alteration in self-representation and identity, with possible psychopathologic repercussions. These reactions are feasible in mental disorders, e.g., post-traumatic stress disorder, adjustment disorder, and psychosomatic disorders. In organ transplantation, the fruitful collaboration between professionals with diverse scientific expertise, calls for both a guarantee for mental health and greater effectiveness in challenging treatments for a viable association between patients, family members and doctors. Integrated and multidisciplinary care should include uniform criteria and procedures for standard assessments, for patient autonomy, adherence to therapy, new coping strategies and the adoption of more appropriate lifestyles. | Concetta De Pasquale Massimiliano Veroux Luisa Indelicato Nunzia Sinagra Alessia Giaquinta Michele Fornaro Pierfrancesco Veroux Maria L Pistorio | 2014 | World Journal of Transplantation2014，4，4： | 3 |
| 3 | Effect of biodegradable chelating agents on heavy metals phytoextraction with Mirabilis jalapa and on its associated bacteria显示文摘 | Alessia C Alessandra C Tiziana L | 2007 | European journal of soil biology2007，43，： | 1 |
| 4 | Neurotransmitter deficits in behavioural and psychological symptoms of Alzheimer' s disease 显示文摘 | ALESSIA L FRANCESCO A GIORGIO S | 2006 | Mechanisms of Ageing and Development2006，127，： | 1 |
| 5 | Yogurt-like beverages made of a mixture of cereals, soy and grape must: microbiology, texture, nutritional and sensory properties显示文摘 | ROSSANA C ALESSIA L ANTONIO T | 2012 | International Journal of Food Microbiology2012，155，3： | 1 |
| 6 | Vitiligo: new and emerging treatments显示文摘 | Torello L Alessia G Zanieri F | 2008 | Dermatol Ther2008，21，2： | 1 |
| 7 | Hall effect in a moving liquid 显示文摘 | Alberto D L Alessia G Francesca M Giampiero P | 2012 | European Journal of Physics2012，33，1： | 1 |
| 8 | Tamsulosin Treatment Increases Clinical Success Rate Of Single Extracorporeal Shock Wave Lithotripsy Of Renal Stones显示文摘 | Giovanni L Alessia M | 2005 | Urology2005，66，1： | 1 |
| 9 | DNA barcoding as a new tool for food traceability显示文摘 | Andrea G Fabrizio D M Alessia L | 2013 | Food Research International2013，50，： | 1 |
| 10 | Characterization of water distribution in bread during storage using magnetic resonance imaging显示文摘 | ALESSIA L AMIR M A YAEL V | 2007 | Magn Resort Imaging2007，25，10： | 1 |
| 11 | New approaches in hepatitis B vaccination for celiac disease显示文摘 | Martina Filippelli Elena Lionetti Alfredo Pulvirenti Alessia Gennaro Angela Lanzafame Gianluigi L Marseglia Carmelo Salpietro Mario La Rosa Salvatore Leonardi | 2014 | Immunotherapy2014，，8： | 1 |
| 12 | The endocannabinoid system and the molecular basis of paralytic ileus in mice显示文摘 | Nicola M Izzo AA Alessia L | 2002 | The FASEB Journal2002，16，14： | 1 |
| 13 | Role of inflammation in diabetic nephropathy 显示文摘 | OLIVER L ALESSIA F ADEEL L | 2008 | Curr Diabetic Rev2008，4，1： | 1 |
| 14 | Characterization of water distri- bution in bread during storage using magnetic resonance imaging 显示文摘 | Alessia L Amir M A Yael V | 2007 | Magnetic Resonance Imaging2007，25，10： | 1 |
| 15 | Neurodegenerative diseases 显示文摘 | MASSIMO G NICOLA L ALESSIA C | 2008 | Radiol Clin N Am2008，46，4： | 1 |
| 16 | Nonalcoholic fatty liver disease prevalence in an Italian cohort of patients with hidradenitis suppurativa: A multi-center retrospective analysis显示文摘BACKGROUND Nonalcoholic fatty liver disease(NAFLD) includes two distinct conditions, with different histologic features and prognosis: non-alcoholic fatty liver(NAFL) and non-alcoholic steatohepatitis(NASH). Furthermore, NASH is the more aggressive necro-inflammatory form, which may accumulate fibrosis and result in End stage liver disease(ESLD). NAFLD is also linked to systemic inflammatory conditions such as psoriasis. NAFLD is currently the most common cause of ESLD in Western countries, becoming a serious public health concern.Hidradenitis suppurativa(HS) is a systemic inflammatory/autoinflammatory disease of the terminal follicular epithelium of the apocrine gland with a prevalence of 0.05% to 4.10%. Due to its systemic inflammatory behavior several comorbidities were recently associated, however liver ones were scarcely assessed.AIM To evaluate the prevalence and characteristics of NASH/NAFL in HS patients.METHODS This retrospective study is a sub-analysis of a larger study carried out in 4 Italian dermatological centers. In this cohort, there were 83 patients: 51 patients with HS only, 20 patients with HS/NAFL and 12 with HS/NASH.RESULTS Inflammatory comorbidities were present in 3.9% of HS only patients, 25% of HS/NAFL patients and 58.3% of HS/NASH patients(P < 0.001). Similarly, mean Autoinflammatory Disease Damage Index(ADDI) was significantly higher among patients with HS/NASH(5.3 ± 2.2, P < 0.001) compared to patients with HS/NAFL or HS only(2.8 ± 1.6 and 2.6 ± 1.4 respectively). Furthermore, ADDI correlates with IHS4 in HS, HS/NAFL and HS/NASH. Diabetic patients have higher Hurley score than not diabetic ones. Ultrasound examination was significantly different in the three groups.CONCLUSION HS patients displayed a high prevalence of NASH/NAFLD and ultrasound examination should be particularly addressed to patients that display high ADDI scores. | Giovanni Damiani Sebastiano Leone Kristen Fajgenbaum Nicola L Bragazzi Alessia Pacifico Rosalynn RZ Conic Paolo DM Pigatto Carlo Maiorana Pierpaolo Poli Emilio Berti Maria C Pace Piergiorgio Malagoli Vincenzo Bettoli Marco Fiore | 2019 | World Journal of Hepatology2019，11，4： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员