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| 1 | Research advances on the multiple uses of Moringa oleifera: a sustainable alternative for socially neglected population显示文摘Moringa oleifera Lam(Moringaceae) is a plant with high nutritional and medicinal value. Native to India, it is now widely distributed throughout tropical and subtropical regions of the world. Its different parts are sources of proteins, vitamins and minerals and present different pharmacological and biotechnological potential. Moreover, M. oleifera seeds are widely used in water and effluent treatment, for their coagulation, flocculation and sedimentation properties, their ability of improving water quality, by reducing organic matter and microbial load, with special applicability in intensive animal production systems, such as aquaculture. In addition, due to its high nutritional value and several medicinal properties, this tree may act as a nutritional and medical alternative for socially neglected populations. In this context, this review gathers information on M. oleifera, emphasizing its chemical constituents, nutritional, pharmacological and antimicrobial properties, applications in the treatment of water effluents, and ecological and social aspects. | Raimunda Samia Nogueira Brilhante Jamille Alencar Sales Vandbergue Santos Pereira Débora de Souza Collares Maia Castelo-Branco Rossana de Aguiar Cordeiro Célia Maria de Souza Sampaio Manoel de Araújo Neto Paiva Joao Bosco Feitosa dos Santos JoséJúlio CostaSidrim Marcos Fábio Gadelha Rocha | 2017 | Asian Pacific Journal of Tropical Medicine2017，10，7： | 10 |
| 2 | Benefit of stem cells and skeletal myoblast cells in dilated cardiomyopathies显示文摘Although some authors suggest that there is mitotic division in the heart,most cardiomyocytes do not have the capacity to regenerate after myocardial infarction and when this occurs there is a deterioration of contractile function,and if the area of infarction is extensive ventricular remodeling may occur,leading to the development of heart failure.Cell transplantation into the myocardium with the goal of recovery of cardiac function has been extensively studied in recent years. The effects of cell therapy are based directly on the cell type used and the type of cardiac pathology.For myocardial ischemia in the hibernating myocardium, bone marrow cells have functional benefits,however these results in transmural fibrosis are not evident. In these cases there is a benefit of implantation with skeletal myoblasts,for treating the underlying cause of disease,the loss of cell contractility. | Luiz César Guarita-Souza Júlio César Francisco Rossana Simeoni Jose Rocha Faria-Neto Katherine Athayde Teixeira de Carvalho | 2011 | World Journal of Cardiology2011，3，3： | 4 |
| 3 | Simultaneous follow-up of mouse colon lesions by colonoscopy and endoluminal ultrasound biomicroscopy显示文摘AIM:To evaluate the potential use of colonoscopy and endoluminal ultrasonic biomicroscopy(eUBM)to track the progression of mouse colonic lesions.METHODS:Ten mice were treated with a single azoxy-methane intraperitoneal injection(week 1)followed by seven days of a dextran sulfate sodium treatment in their drinking water(week 2)to induce inflammationassociated colon tumors.eUBM was performed simultaneously with colonoscopy at weeks 13,17-20 and21.A 3.6-F diameter 40 MHz mini-probe catheter was used for eUBM imaging.The ultrasound mini-probe catheter was inserted into the accessory channel of a pediatric flexible bronchofiberscope,allowing simultaneous acquisition of colonoscopic and eUBM images.During image acquisition,the mice were anesthetized with isoflurane and kept in a supine position over a stainless steel heated surgical waterbed at 37℃.Both eUBM and colonoscopic images were captured and stored when a lesion was detected by colonoscopy or when the eUBM image revealed a modified colon wall anatomy.During the procedure,the colon was irrigated with water that was injected through a flush port on the mini-probe catheter and that acted as the ultrasound coupling medium between the transducer and the colon wall.Once the acquisition of the last eUBM/colonoscopy section for each animal was completed,the colons were fixed,paraffin-embedded,and stained with hematoxylin and eosin.Colon images acquired at the first time-point for each mouse were compared with subsequent eUBM/colonoscopic images of the same sites obtained in the following acquisitions to evaluate lesion progression.RESULTS:All 10 mice had eUBM and colonoscopic images acquired at week 13(the first time-point).Two animals died immediately after the first imaging acquisition and,consequently,only 8 mice were subjected to the second eUBM/colonoscopy imaging acquisition(at the second time-point).Due to the advanced stage of colonic tumorigenesis,5 animals died after the second time-point image acquisition,and thus,only three were subjected to the third eUBM/colonoscopy imaging acquisition(the third time-point).eUBM was able to detect the four layers in healthy segments of colon:the mucosa(the first hyperechoic layer moving away from the mini-probe axis),followed by the muscularis mucosae(hypoechoic),the submucosa(the second hyperechoic layer)and the muscularis externa(the second hypoechoic layer).Hypoechoic regions between the mucosa and the muscularis externa layers represented lymphoid infiltrates,as confirmed by the corresponding histological images.Pedunculated tumors were represented by hyperechoic masses in the mucosa layer.Among the lesions that decreased in size between the first and third time-points,one of the lesions changed from a mucosal hyperplasia with ulceration at the top to a mucosal hyperplasia with lymphoid infiltrate and,finally,to small signs of mucosal hyperplasia and lymphoid infiltrate.In this case,while lesion regression and modification were observable in the eUBM images,colonoscopy was only able to detect the lesion at the first and second time-points,without the capacity to demonstrate the presence of lymphoid infiltrate.Regarding the lesions that increased in size,one of them started as a small elevation in the mucosa layer and progressed to a pedunculated tumor.In this case,while eUBM imaging revealed the lesion at the first time-point,colonoscopy was only able to detect it at the second time-point.All colonic lesions(tumors,lymphoid infiltrate and mucosal thickening)were identified by eUBM,while colonoscopy identified just76%of them.Colonoscopy identified all of the colonic tumors but failed to diagnose lymphoid infiltrates and increased mucosal thickness and failed to differentiate lymphoid infiltrates from small adenomas.During the observation period,most of the lesions(approximately67%)increased in size,approximately 14%remained unchanged,and 19%regressed.CONCLUSION:Combining eUBM with colonoscopy improves the diagnosis and the follow-up of mouse colonic lesions,adding transmural assessment of the bowel wall. | Rossana C Soletti Kelly Z Alves Marcelo AP de Britto Dyanna G de Matos Mnica Soldan Helena L Borges Joo C Machado | 2013 | World Journal of Gastroenterology2013，19，44： | 1 |
| 4 | Redirection of flux through the FPP branch-point in Saccharomyces cerevisiae by down-regulating squalene synthase显示文摘 | PARADISE E M JAMES K ROSSANA C | 2008 | Biotechnology and Bioengineering2008，100，2： | 1 |
| 5 | Effect of sourdough fermentation on stabilisation, and chemical and nulritional characteristics of wheat germ显示文摘 | CARLO G R LUANA N ROSSANA C | 2010 | Food Chemistry2010，119，： | 1 |
| 6 | Comparison of two different doses of iodide in the prevention of gestational goiter in marginal iodine deficiency: a longitudinal study显示文摘 | Lucia A Doretta M Rossana C | 2002 | Eur J Endocrinol2002，147，： | 1 |
| 7 | Variant of keratoderma hereditaria m uti- lans (Vohwinkel' ssyndrome) 显示文摘 | Camiosa C Rossana C | 1984 | Arch Dermatol1984，120，10： | 1 |
| 8 | Evaluation of the effects of anti-thromboxane agents in platelet-vessel wall interaction显示文摘 | Carola B Paola C Rossana B | 2002 | European Journal of Pharmacology2002，443，13： | 1 |
| 9 | Micronized by- products from debranned durum wheat and sourdough fermentation enhanced the nutritional, textural and sensory features of bread显示文摘 | CARLO G R ROSSANA C FRANCESCO M | 2012 | Food Research International2012，46，： | 1 |
| 10 | Yogurt-like beverages made of a mixture of cereals, soy and grape must: microbiology, texture, nutritional and sensory properties显示文摘 | ROSSANA C ALESSIA L ANTONIO T | 2012 | International Journal of Food Microbiology2012，155，3： | 1 |
| 11 | Observational study on the stability of the psychological status during normal pregnancy and increased blood levels of neuroactive steroids with GABA-A receptor agonist activity 显示文摘 | Anna M P Sandra R Rossana C | 2006 | Psychoneuroendocrinology2006，31，4： | 1 |
| 12 | Variant of keratoderma hereditaria mutilans ( Vohwinkel' s syndrome ) 显示文摘 | Camiosa C Rossana C | 1984 | Arch Dermatol1984，120，10： | 1 |
| 13 | Basicity ofdodecyltrimethylammonium hydroxide 显示文摘 | Marcela A Morini Rossana M Minardi Pablo C Schulz | 1995 | Colloids and SurfacesA1995，103，： | 1 |
| 14 | Inhaled corticosteroids reduce neutropnilic bronchial inflammation in patients with chronic obstructive pulmonary disease显示文摘 | Marco C Elsa M Rossana DP | 1998 | Thorax1998，53，7： | 1 |
| 15 | Sequence of a c-DNA for mouse thymidylate synthase reveals striking similarity with the prokaryotic enzyme显示文摘 | PERRYMAN S M ROSSANA C DENG T | 1986 | Mol Biol Evol1986，，3： | 1 |
| 16 | Tassinari,Petrogenesis of the early Createous Valle Chico igneous complex (SE Uruguay):Relationships with Parana-Etendeka magmatism显示文摘 | Michele Lustrino Leone Melluso Pietro Brotzu Celso B Gomes Lucio Morbidelli Rossana Muzio Excelso Ruberti Colombo C G | 2005 | Lithos2005，82，： | 1 |
| 17 | Potassium trim- ethylsilanolate induced cleavage of 1,3-oxazolidin-2-and 5-ones, and application to the synthesis of (R)-salmet- erol显示文摘 | Diane M C Rossana P Panayiotis A P | 2003 | Org Biomol Chem2003，，1： | 1 |
| 18 | Evaluation of the effects of an- ti-thromboxane agents in platelet-vessel wall interaction 显示文摘 | Carola B Paola C Rossana B | 2002 | European Journal of Pharmacology2002，443，13： | 1 |
| 19 | Bullous lichen planus:diagnosis by indirect immunofluorescenee and treatment with dapsone显示文摘 | CAMISA C NEFF J C ROSSANA C | 1986 | J Am Acad Dermatol1986，14，3： | 1 |
| 20 | The effects of environmental factors on the virulence of Trichomonas vaginalis显示文摘 | Elisa E. Figueroa-Angulo Francisco J. Rendón-Gandarilla Jonathan Puente-Rivera Jaeson S. Calla-Choque Rosa E. Cárdenas-Guerra Jaime Ortega-López Laura I. Quintas-Granados M. Elizbeth Alvarez-Sánchez Rossana Arroyo | 2012 | Microbes and Infection2012，，15： | 1 |
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