|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Hepatitis B vaccine by intradermal route in non responder patients:An update显示文摘Vaccination is the main prophylactic measure to reduce the mortality caused by hepatitis B virus(HBV)infection in healthy subjects since the immune response to hepatitis B recombinant vaccination occurs in over 90%of general population.Individuals who develop an antiHBs titer less than 10 mIU/mL after primary vaccination cycle are defined'no responders'.Many factors could cause a non response to the HBV vaccination,such as administration of the vaccine in buttocks,impaired vaccine storage conditions,drug abuse,smoking,infections and obesity.Moreover there are some diseases,like chronic kidney disease,human immunodeficiency virus infection,chronic liver disease,celiac disease,thalassaemia,typeⅠdiabetes mellitus,down’s syndrome and other forms of mental retardation that are characterized by a poorer response to HBV vaccination than healthy subjects.To date it is still unclear how to treat this group of patients at high risk of hepatitis B infection.Recent studies seem to indicate that the administration of HBV recombinant vaccine by the intradermal route is very effective and could represent a more useful strategy than intramuscular route.This review focuses on the use of anti hepatitis B vaccine by intradermal route as alternative to conventional intramuscular vaccine in all non responder patients.A comprehensive review of the literature using PubMed database,with appropriate terms,was undertaken for articles in English published since 1983.The literature search was undertaken in September 2013. | Martina Filippelli Elena Lionetti Alessia Gennaro Angela Lanzafame Teresa Arrigo Carmelo Salpietro Mario La Rosa Salvatore Leonardi | 2014 | World Journal of Gastroenterology2014，20，30： | 12 |
| 2 | Immune response to hepatitis B virus vaccine in celiac subjects at diagnosis显示文摘AIM To evaluate hepatitis B virus(HBV) vaccine response and correlation with human leukocyte antigens(HLA) and/or gluten intake in celiac patients at diagnosis.METHODS Fifty-one patients affected by celiac disease, diagnosed at the Department of Pediatrics of the University of Catania(Italy), were recruited. All patients were tested at admission for immunization against HBV, according to findings from analysis of quantitative HBV surface antibody(anti-HBs). The anti-HBs titer was measured by enzyme-linked immunosorbent assay. Following the international standards, subjects with antibody titer < 10 IU/L were defined as non-responders. The prevalence of responders and non-responders among celiac subjects and the distribution of immunization for age were examined. In addition, the prevalence of responders and non-responders was assessed for correlation to HLA and clinical features at diagnosis of celiac disease.RESULTS The entire study population was divided into three groups according to age: 24 patients aged between 0to 5.5 years(48.9%, group A); 16 aged between 5.5 and 9.5 years(30.61%, group B); 9 aged between 9.5 and 17 years(18.75%, group C). Comparison of the percentage of responders and non-responders between the youngest and the oldest age group showed no significant difference between the two groups(P > 0.05). With regard to the HLA haplotype, comparison of the distribution of vaccination response showed no statistically significant difference between the different genotypes(homozygosity for the HLADQ2 haplotype compared with HLADQ2/DQ8 heterozygosity or other haplotypes; P > 0.05). Moreover, distribution of the responders according to clinical features of celiac disease showed no statistically significant differences(P > 0.05).CONCLUSION This prospective study confirmed the lower percentage of response to HBV vaccine in celiac subjects. However, the underlying mechanism remains unclear and further studies are needed. | Martina Filippelli Maria Teresa Garozzo Antonino Capizzi Massimo Spina Sara Manti Lucia Tardino Carmelo Salpietro Salvatore Leonardi | 2016 | World Journal of Hepatology2016，8，26： | 5 |
| 3 | Helicobacter pylori infection and atopic diseases:Is there a relationship? A systematic review and meta-analysis显示文摘AIM:To review and conduct a meta-analysis of the existing literature on the relationship between Helicobacter pylori(H.pylori),atopy and allergic diseases.METHODS:Studies published in English assessing the prevalence of atopy and/or allergic diseases in patients with H.pylori infection and the prevalence of H.pylori infection in patients with atopy and/or allergic diseases were identified through a MEDLINE search(1950-2014).Random-effect model was used for the meta-analysis.RESULTS:Pooled results of case-control studies showed a significant inverse association of H.pylori infection with atopy/allergic disease or with exclusively atopy,but not with allergic disease,whereas pooled results of cross-sectional studies showed only a significant association between allergic disease and H.pylori infection.CONCLUSION:There is some evidence of an inverse association between atopy/allergic diseases and H.pylori infection,although further studied are needed. | Elena Lionetti Salvatore Leonardi Angela Lanzafame Maria Teresa Garozzo Martina Filippelli Stefania Tomarchio Viviana Ferrara Carmelo Salpietro Alfredo Pulvirenti Ruggiero Francavilla Carlo Catassi | 2014 | World Journal of Gastroenterology2014，20，46： | 3 |
| 4 | Randomised trial comparing biweekly oxaliplatin plus oral capecitabine versus oxaliplatin plus i.v. bolus fluorouracil/leucovorin in metastatic colorectal cancer patients: results of the Southern Italy Cooperative Oncology study 0401显示文摘 | Pasquale Comella Bruno Massidda Gianfranco Filippelli Antonio Farris Donato Natale Giuseppe Barberis Luigi Maiorino Sergio Palmeri Michele Cannone Giovanni Condemi | 2009 | Journal of Cancer Research and Clinical Oncology2009，，2： | 2 |
| 5 | Endothelin-1 affects capsaiein-evoked release of neuropeptides from rat vas deferens 显示文摘 | Filippelli A Faleiani M Piucci B | 1999 | Eur J Pharmacol1999，364，23： | 1 |
| 6 | Seasonar lity and children's blood lead levels: developing a predictive model using climatic variables and blood lead data from Indianapolis, Indiana, Syracuse, New York, and New Orleans, Louisiana(USA) 显示文摘 | Laidlaw MA Mielke HW Filippelli GM | 2005 | Environ Heath Perspect2005，113，6： | 1 |
| 7 | Tile combination of gemcitabine and vinorelbine is an active regimen as second-line therapy in patients with metastatic breast cancer pretreated with taxanes and/or anthracyclines: a phase Ⅰ - Ⅱ study 显示文摘 | Morabito A Filippelli G Palmeri S | 2003 | Breast Cancer Res Treat2003，78，1： | 1 |
| 8 | Chest wall kinematics during chemically stimulated breathing in healthy man显示文摘 | Filippelli M Romagnoli I Gigliotti F et a1 | 2002 | Lung2002，180，6： | 1 |
| 9 | M Mastalen Chemical Fractionation of Metals in Wetland Sediments: Indiana Dunes National Lakeshore 显示文摘 | Dollar Nancy L C J Souch G M Filippelli | 2001 | Environmental Science & Technology2001，35，18： | 1 |
| 10 | Phosphorus geochemistry of equatorial Pacific sediments显示文摘 | FILIPPELLI G M DELANEY M L | 1996 | Geochimica et Cosmochimica Acta1996，60，9： | 1 |
| 11 | Phosphate rock formation and marine phos- phorus geochemistry:The deep time perspective显示文摘 | Filippelli G M | 2011 | Chemo- sphere2011，84，6： | 1 |
| 12 | A eombined CDB-MAGIC method for the determination of phosphorus associated with sedimentary iron oxyhydroxides 显示文摘 | Huerta-Diaz M A Tovar-S6nchez A Filippelli G | 2005 | Applied Geochemistry2005，20，11： | 1 |
| 13 | Effects of docosahexaenoic acid on ( i ) increase induced by doxorubicin in ventricular rat cardiomyocytes 显示文摘 | RVitelli M Filippelli A Rinaldi B | 2002 | Life Sci2002，71，16： | 1 |
| 14 | Controls on phosphorus concentration and accumulation in oceanic sediments显示文摘 | FILIPPELLI G M | 1997 | Marine Geology1997，139，： | 1 |
| 15 | Chronic peripheral ouabain treatment affects the brain endothelin system of rats显示文摘 | Di Filippo C Filippelli A Rinaldi B | 2003 | J Hypertens2003，21，4： | 1 |
| 16 | Chronic peripheral ouabain treatment affects the brain endothelin system of rats 显示文摘 | Di Filippo C Filippelli A Rinaldi B | 2003 | J Hypertens2003，21，4： | 1 |
| 17 | Phosphorus and iron sedimentation in the Southern Ocean on Glacial/Interglacial time scales显示文摘 | LATIMER J C FILIPPELLI G M | 1997 | American Geophysical Union EOS (Abstracts)1997，78，17： | 1 |
| 18 | Carbon and phosphorus cycling in anoxic sediments of the Saanich Inlet, British Columbia显示文摘 | Filippelli G | 2001 | Marine Geology2001，174，： | 1 |
| 19 | The oceanic phosphorus cycle and continental weathering during the Neogene 显示文摘 | Filippelli G M Delaney M L | 1994 | Paleoceanography1994，9，5： | 1 |
| 20 | An apparent contradiction in the role of phosphorus in Cenozoic chemical mass balances for the world ocean显示文摘 | DELANEY M L FILIPPELLI G M | 1994 | Paleoceanography1994，9，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员