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| 1 | Human bocavirus: Current knowledge and future challenges显示文摘Human bocavirus(HBoV) is a parvovirus isolated about a decade ago and found worldwide in both respiratory samples, mainly from early life and children of 6-24 mo of age with acute respiratory infection, and in stool samples, from patients with gastroenteritis. Since then, other viruses related to the first HBoV isolate(HBoV 1), namely HBoV 2, HBoV 3 and HBoV 4, have been detected principally in human faeces. HBo Vs are small nonenveloped single-stranded DNA viruses of about 5300 nucleotides, consisting of three open reading frames encoding the first two the non-structural protein 1(NS1) and nuclear phosphoprotein(NP1) and the third the viral capsid proteins 1 and 2(VP1 and VP2). HBoV pathogenicity remains to be fully clarified mainly due to the lack of animal models for the difficulties in replicating the virus in in vitro cell cultures, and the fact that HBo V infection is frequently accompanied by at least another viral and/or bacterial respiratory and/or gastroenteric pathogen infection. Current diagnostic methods to support HBoV detection include polymerase chain reaction, real-time PCR, enzymelinked immunosorbent assay and enzyme immunoassay using recombinant VP2 or virus-like particle capsid proteins, although sequence-independent amplification techniques combined with next-generation sequencing platforms promise rapid and simultaneous detection of the pathogens in the future. This review presents the current knowledge on HBoV genotypes with emphasis on taxonomy, phylogenetic relationship and genomic analysis, biology, epidemiology, pathogenesis and diagnostic methods. The emerging discussion on HBoV s as true pathogen or innocent bystander is also emphasized. | Marcello Guido Maria Rosaria Tumolo Tiziano Verri Alessandro Romano Francesca Serio Mattia De Giorgi Antonella De Donno Francesco Bagordo Antonella Zizza | 2016 | World Journal of Gastroenterology2016，22，39： | 11 |
| 2 | Shading the TRF2 recruiting function: a new horizon in drug development显示文摘 | Di Maro S Zizza P Salvati E | 2014 | J Am Chem Soc2014，136，16： | 1 |
| 3 | Diagnosis of acute aortic dissection by D-dimer: the International Registry of Acute Aortic Dissection Substudy on Bi- omarkers (IRAD-Bio) experience 显示文摘 | Suzuki T Distante A Zizza A | 2009 | Circulation2009，119，20： | 1 |
| 4 | Diagnosis of aeute aortic dissection by D - dimer: the International Registry of Acute Aor- tic Dissection Substudy on Biomarkers ( IRAD - Bio) experi- ence 显示文摘 | Suzuki T Distante A Zizza A | 2009 | Circulation2009，119，20： | 1 |
| 5 | Diagnosis of acute aorticdissection by D-dimer: the International Registry of Acute AorticDissection Substudy on Biomarkers (IRAD-Bio) experience 显示文摘 | Suzuki T Distante A Zizza A | 2009 | Circulation2009，119，20： | 1 |
| 6 | Diagnosis of acute aortic dissection by D-dimer: the International Registry of Acute Aortic Dissection Substudy on Biomarkers (IRAD-Bio) experience 显示文摘 | Suzuki T Distante A Zizza A | 2009 | Circulation2009，119，20： | 1 |
| 7 | Diagnosis of acute aor- tic dissection by D-dimer the international Registry of acute aortic dissection substudy on biomarkers (IRAD-Bio) ex- perience 显示文摘 | Suzuki T Distante A Zizza A | 2009 | Circulation2009，119，20： | 1 |
| 8 | Dysmorphic concern symptoms and personality disorders:A clinical investigation in patients seeking cosmetic surgery显示文摘 | Bellino S Zizza M Paradiso E | 2006 | Psychiatry Research2006，144，1： | 1 |
| 9 | Diagnosis of acute aortic dis-section by D-dimer: the International Registry of Acute Aortic Dis-section Substudy on Biomarkers (IRAD-Bio)experience显示文摘 | Suzuki T Distante A Zizza A | 2009 | Circu-lation2009，119，20： | 1 |
| 10 | Combined Treatment of Major Depression in Patients With Borderline Personality Dis- order:A Comparis-on With Pharmacotherapy显示文摘 | Silvio Bellino MD Monica Zizza Ph B | 2006 | Can J Psy- chiatry2006，51，： | 1 |
| 11 | Preliminary experience with the smooth muscle troponin-like protein,calponin,as a novel biomarker for diagnosing acute aortic dissection显示文摘 | Suzuki T Distante A Zizza A | 2008 | Eur Heart J2008，29，11： | 1 |
| 12 | Diagnosis of acute aortic dissec- tion by D-dimer: the international registry of acute aortie dissection sub study on biomarkers experience显示文摘 | Suzuki T Distante A Zizza A | 2009 | Circulation2009，119，20： | 1 |
| 13 | Diagnosis of Acute Aortic Dissection by D-Dimer: The International Registry of Acute Aortic Dissection Substudy on Biomarkers (IRAD-Bio) Experience显示文摘 | Toru Suzuki Alessandro Distante Antonella Zizza Santi Trimarchi Massimo Villani Jorge Antonio Salerno Uriarte Luigi De Luca Tupputi Schinosa Attilio Renzulli Federico Sabino Richard Nowak Robert Birkhahn Judd E. Hollander Francis Counselman Ravi Vijayendr | 2009 | Circulation2009，，20： | 1 |
| 14 | Contribution of snacking to older adults' vitamin, carotenoid, and mineral intakes 显示文摘 | ZIZZA C A ARSIWALLA D D ELLISON K J | 2010 | J Am Dieter Assoc2010，110，5： | 1 |
| 15 | Weighty concerns:the growing prevalence of obesity among older adults显示文摘 | HOUSTON D K NICKLAS B J ZIZZA C A | 2009 | J Am Diet Assoc2009，109，11： | 1 |
| 16 | Preliminary experience with the smooth muscle troponin-like protein, calponin, as a novel biomarker for diagnosing acute aortic dissection 显示文摘 | Suzukil T Distante A Zizza A etal | 2008 | Eur Heart J2008，29，11： | 1 |
| 17 | Glycoconjugate histochemistry of the digestive tract of Triturus carnifex (Amphibia, Caudata)显示文摘 | Giuseppa Esterina Liquori Maria Mastrodonato Sara Zizza Domenico Ferri | 2007 | Journal of Molecular Histology2007，，3： | 1 |
| 18 | Diagnosis of acute aortic dissection by D-dimer:the International Registry of Acute Aortic Dissection Substudy on Biomarkers (IRAD-Bio) experience显示文摘 | Suzuki T Distante A Zizza A | 2009 | Circulation2009，119，20： | 1 |
| 19 | Preliminary experience with the smooth muscle troponin-like protein, calponin, as a novel biomarker for diagnosing a- cute aortic dissection 显示文摘 | Suzuki T Distante A Zizza A | 2008 | Eur Heart J2008，29，11： | 1 |
| 20 | Diagnosis of acute aortic dissection by D-Dimer: the International Registry of Acute Aortic Dissection Substudy on Biomarkers (IRAD- Bio) expereience显示文摘 | Suzuki T Distante A Zizza A | 2009 | Circulation2009，119，20： | 1 |
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