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| 1 | Overexpression of micro RNA_(40)8 enhances photosynthesis, growth, and seed yield in diverse plants显示文摘The ability of a plant to produce grain, fruit, or forage depends ultimately on photosynthesis. There have been few attempts, however, to study micro RNAs, which are a class of endogenous small RNAs post-transcriptionally programming gene expression, in relation to photosynthetic traits. We focused on miR_(40)8, one of the most conserved plant miRNAs, and overexpressed it in parallel in Arabidopsis, tobacco, and rice. The transgenic plants all exhibited increased copper content in the chloroplast, elevated abundance of plastocyanin,and an induction of photosynthetic genes. By means of gas exchange and optical spectroscopy analyses, we showed that higher expression of miR_(40)8 leads to enhanced photosynthesis through improving efficiency of irradiation utilization and the capacity for carbon dioxide fixation. Consequently, miR_(40)8 hyper-accumulating plants exhibited higher rate of vegetative growth. An enlargement of seed size was also observed in all three species overproducing miR_(40)8. Moreover, we conducted a 2-year-two-location field trial and observed miR_(40)8 overexpression in rice significantly increased yield, which was primarily attributed to an elevation in grain weight. Taken together, these results demonstrate that miR_(40)8 is a positive regulator of photosynthesis and that its genetic engineering is a promising route for enhancing photosynthetic performance and yield in diverse plants. | Jiawei Pan Dahui Huang Zhonglong Guo Zheng Kuang He Zhang Xinyu Xie Zengfeng Ma Shaopei Gao Manuel T.Lerdau Chengcai Chu Lei Li | 2018 | Journal of Integrative Plant Biology2018，60，4： | 8 |
| 2 | Histopathological Features and Viral Antigen Distribution in the Lung of Fatal Patients with Enterovirus 71 Infection显示文摘Dear Editor,Enterovirus 71(EV71)infection causes hand-foot-andmouth disease(HFMD)in infants and children.Patients with HFMD usually have good prognosis;however,in some extreme cases the infection can be accompanied by central nervous system diseases,eventually leading to cardiorespiratory failure,and even death.Currently。 | Zhenli Liang Hongbo Pan Xijing Wang Yinchuan Zhu Yiwu Dang Xiaohui Fan Lingxi Gao Zengfeng Zhang | 2018 | Virologica Sinica2018，33，3： | 4 |
| 3 | Identification of Major Locus Bph35 Resistance to Brown Planthopper in Rice显示文摘An introgression line RBPH660,derived from wild rice Oryza rufipogon,showed stable resistance to brown planthopper(BPH).Segregation analysis indicated BPH resistance of RBPH660 was controlled by multiple genes/QTLs.By using the bulked segregant analysis(BSA)-seq method,two genomic regions harboring QTLs resistance to BPH were identified from 1.20 to 16.70 Mb on chromosome 4 and from 10.20 to 12.60 Mb on chromosome 9 in RBPH660,respectively.A major resistance locus,designated as Bph35 accounting for 51.27%of the phenotypic variation with a LOD score of 42.51,was mapped to the candidate region of chromosome 4 between In Del(insertion-deletion)markers PSM16 and R4 M13.For fine mapping of Bph35,one simple sequence repeat and three newly developed In Del markers were used to screen the recombinants.Finally,the Bph35 locus was delimited in the region from 6.28 to 6.93 Mb and there were 18 predicted protein-encoding genes with a total of 114 non-synonymous single nucleotide polymorphism(SNP)variant sites between the resistant and susceptible parents.Out of these genes,Os04 g0193950,encoding a putative NB-ARC(nucleotidebinding adaptor shared by APAF-1,R proteins and CED-4)and LRR(leucine-rich repeat)domain protein with nine non-synonymous SNP substitutions in its coding sequence regions,might be the candidate gene for Bph35.These findings would facilitate the map-based cloning of the Bph35 gene and development of resistant varieties against BPH in rice. | ZHANG Yuexiong QIN Gang MA Qianqian WEI Minyi YANG Xinghai MA Zengfeng LIANG Haifu LIU Chi LI Zhenjing LIU Fang HUANG Dahui LI Rongbai | 2020 | Rice science2020，27，3： | 3 |
| 4 | Tubular/helical architecture construction based on rolled-up AlN nanomembranes and resonance as optical microcavity显示文摘Aluminum nitride(AlN)has attracted a great amount of interest due to the fact that these group III–V semiconductors present direct band gap behavior and are compatible with current micro-electro-mechanical systems.In this work,three dimensional(3D)AlN architectures including tubes and helices were constructed by rolling up AlN nanomembranes grown on a silicon-on-insulator wafer via magnetron sputtering.The properties of the AlN membrane were characterized through transmission electron microscopy and X-ray diffraction.The thickness of AlN nanomembranes could be tuned via the RIE thinning method,and thus micro-tubes with different diameters were fabricated.The intrinsic strain in AlN membranes was investigated via micro-Raman spectroscopy,which agrees well with theory prediction.Whispering gallery mode was observed in AlN tubular optical microcavity in photoluminescence spectrum.A postprocess involving atomic layer deposition and R6G immersion were employed on as-fabricated AlN tubes to promote the Q-factor.The AlN tubular micro-resonators could offer a novel design route for Si-based integrated light sources.In addition,the rolled-up technology paves a new way for AlN 3D structure fabrication,which is promising for AlN application in MEMS and photonics fields. | Jinyu Yang Yang Wang Lu Wang Ziao Tian Zengfeng Di Yongfeng Mei | 2020 | Journal of Semiconductors2020，41，4： | 2 |
| 5 | Research on System Control and Energy Management Strategy of Flux-Modulated Compound-Structure Permanent Magnet Synchronous Machine显示文摘The flux-modulated compound-structure permanent magnet synchronous machine (CS-PMSM), composed of a brushless double rotor machine (DRM) and a conventional permanent magnet synchronous machine (PMSM), is a power split device for plug-in hybrid electric vehicles. In this paper, its operating principle and mathematical model are introduced. A modified current controller with decoupled state feedback is proposed and verified. The system control strategy is simulated in Matlab, and the feasibility of the control system is proven. To improve fuel economy, an energy management strategy based on fuzzy logic controller is proposed and evaluated by the Urban Dynamometer Driving Schedule (UDDS) drive cycle. The results show that the total energy consumption is similar to that of Prius 2012. | Jiaqi Liu Chengde Tong Zengfeng Jin Guangyuan Qiao Ping Zheng | 2017 | CES Transactions on Electrical Machines and Systems2017，1，2： | 2 |
| 6 | Application of confocal laser Raman spectroscopy on marine sediment microplastics显示文摘Marine sediment is the primary sink of microplastics and is an indicator of pollution levels.However,although there are well-developed detection methods,detection is rarely focused on lowmicrometer-sized particles,mainly due to technique limitations.In this study,a simplifi ed process omitting digestion procedures was developed to pretreat microplastics obtained from marine sediment and was coupled with micro-Raman spectroscopy to identify microplastics.Based on the overall analysis of the characteristic peak assignments,a Raman spectral reference library was constructed for 18 types of plastic.In addition,the eff ects of the measurement parameters were systematically described.Field research was then conducted to validate the developed process and investigate microplastic contamination in Huiquan Bay,Qingdao,China.This simplifi ed process could retain the original appearance of microparticles and accomplish the detection of<500μm-sized microplastics in environmental samples.Microplastics in the size range of 10-150μm accounted for 76%of all microplastics,and 56%of the total particles was particles smaller than 50μm.Polypropylene(42%)and polyethylene(20%)were predominant components of the particles.In particular,polypropylene particles smaller than 10μm were identifi ed in marine sediment.This work demonstrates that Raman spectroscopy is not only an eff ective tool for detecting environmental particles but also highly applicable for identifying particles extracted from marine sediment. | LIU Jing ZHANG Xin DU Zengfeng LUAN Zhendong LI Lianfu XI Shichuan WANG Bing CAO Lei YAN Jun | 2020 | Journal of Oceanology and Limnology2020，38，5： | 2 |
| 7 | Investigation of a novel biomarker, neuropilin-1, and its application for poor prognosis in acute myeloid leukemia patients显示文摘 | Jianqiang Zhao Liufang Gu Chengliang Li Weiguo Ma Zengfeng Ni | 2014 | Tumor Biology2014，，： | 1 |
| 8 | Gorenstein projective dimension with respect to a semidualizing module显示文摘 | LIU Zengfeng HUANG Zhaoyong XU Aimin | 2013 | Comm Algebra2013，2，： | 1 |
| 9 | Studyofbiodegradabilityofdi(2-ethylhexyl)phthalate[J]显示文摘 | CHAISufen(柴素芬) ZENGFeng(曾锋) FUJiamo(傅家谟) etal | | 中山大学学报:自然科学版0，，： | 1 |
| 10 | Analysis of Hydrocarbon Mixture Performance of a Dual-Channel Swirl Engine显示文摘In order to understand and improve the oil and gas mixing performance of a dual-channel vortex chamber diesel engine,the BH175F dual-channel vortex chamber combustion system was used as the research foundation,and the oil-gas mixture process of the combustion system was numerically analyzed.By analyzing the cylinder temperature,cylinder pressure,mixing process and combustion process of the combustion system,the mixture performance of the combustion system was studied.Results indicated that:The mixture of the compression Top Dead Center(TDC)started to enter the main combustion chamber through the start-up hole;when the piston reached 4°After Top Dead Center(ATDC),the mixture started to enter the main combustion chamber through the connecting channels A and B,and the high-concentration mixture entered the main combustion from the start-up hole;when the piston continued running down to 20°and 25°ATDC,it could be seen that the main combustion chamber mixture was already relatively uniform;besides,when the equivalence ratio was between 0.8 and 1,the air-ftiel mixture was unevenly distributed in the main combustion chamber.It provides guidance for further improvement of the combustion system. | YUAN Wenhua HUANG Qilin FU Jun LIAO Jingjing LI Yu HE Yong ZHANG Zengfeng MA Yi | 2020 | Journal of Thermal Science2020，29，6： | 1 |
| 11 | Fabrication of high quality strained SiGe on Si substrate by RPCVD显示文摘In this study,the growth kinetics of SiGe in a reduced pressure chemical vapor deposition system using dichlorosilane(SiH2Cl2) and germane(GeH4) as the Si and Ge precursors were investigated.The SiGe growth rate and Ge content were found to depend on the deposition temperature,GeH4 flow and reactor chamber pressure.The SiGe growth rate escalates with increasing deposition temperature,while the Ge content is reduced.The SiGe growth rate accelerates with increasing GeH4 flow,while the Ge content increases more slowly.According to the experimental data,a new relationship between Ge content(x) and F(GeH4)/F(SiH2Cl2) mass flow ratio is deduced:x2.5/(1x) = nF(GeH4)/F(SiH2Cl2).The SiGe growth rate and Ge content improve with increasing reactor chamber pressure.By selecting proper precursor flows and reactor pressure,SiGe films with the same Ge content can be fabricated at various temperatures.However,the quality of the SiGe crystals is clearly dependent on the deposition temperature.At lower deposition temperature,higher crystalline quality is achieved.Because the growth rate dramatically drops with lower temperatures,the optimum growth temperature must be a compromise between the crystalline quality and the growth rate.X-ray diffraction,Raman scattering spectroscopy and atomic force microscopy results indicate that 650°C is the optimum temperature for fabrication of Si0.75Ge0.25 film. | XUE ZhongYing CHEN Da LIU LinJie JIANG HaiTao BIAN JianTao WEI Xing DI ZengFeng ZHANG Miao WANG Xi | 2012 | Chinese Science Bulletin2012，57，15： | 1 |
| 12 | Radiation-induced tumor immune microenvironments and potential targets for combination therapy显示文摘As one of the four major means of cancer treatment including surgery,radiotherapy(RT),chemotherapy,immunotherapy,RT can be applied to various cancers as both a radical cancer treatment and an adjuvant treatment before or after surgery.Although RT is an important modality for cancer treatment,the consequential changes caused by RT in the tumor microenvironment(TME)have not yet been fully elucidated.RT-induced damage to cancer cells leads to different outcomes,such as survival,senescence,or death.During RT,alterations in signaling pathways result in changes in the local immune microenvironment.However,some immune cells are immunosuppressive or transform into immunosuppressive phenotypes under specific conditions,leading to the development of radioresistance.Patients who are radioresistant respond poorly to RT and may experience cancer progression.Given that the emergence of radioresistance is inevitable,new radiosensitization treatments are urgently needed.In this review,we discuss the changes in irradiated cancer cells and immune cells in the TME under different RT regimens and describe existing and potential molecules that could be targeted to improve the therapeutic effects of RT.Overall,this review highlights the possibilities of synergistic therapy by building on existing research. | Siyu Guo Yihan Yao Yang Tang Zengfeng Xin Dang Wu Chao Ni Jian Huang Qichun Wei Ting Zhang | 2023 | Signal Transduction and Targeted Therapy2023，8，6： | 1 |
| 13 | Cluster warhead dispersing technique and its interior ballistic calculation显示文摘 | TAN Dacheng YUAN Zengfeng | | 0，，： | 1 |
| 14 | 显示文摘 | CHENLi-xuan(陈丽旋) ZENGFeng(曾锋) CuiKun-yan(崔昆燕) | | 广西师范大学学报:自然科学版0，，： | 1 |
| 15 | Reappraisal of mesenchymal chondrosarcoma: novel morphologic observations of the hyaline cartilage and endochondral ossification and β-catenin, Sox9, and osteocalcin immunostaining of 22 cases显示文摘 | Julie C. Fanburg-Smith Aaron Auerbach Jayson S. Marwaha Zengfeng Wang Elisabeth J. Rushing | 2010 | Human Pathology2010，，5： | 1 |
| 16 | Application of image correction and bit-plane fusion in generalized PCA based face recognition显示文摘 | WANG HUIYUAN LENG YAN WANG ZENGFENG | 2007 | Pattern Recognition Letters2007，28，16： | 1 |
| 17 | TNFα inhibitor C87 sensitizes EGFRvⅢ transfected glioblastoma cells to gefitinib by a concurrent blockade of TNFα signaling显示文摘Objective: More than half of human glioblastomas show EGFR gene amplification and mutation, but EGFR inhibitors have not been effective in treating EGFR-positive glioblastoma patients.The mechanism behind this type of primary resistance is not well understood.The aim of this study was to investigate gefitinib resistance in glioblastoma, and explore ways to circumvent this significant clinical problem.Methods: MTT method was used to test the cell viability after EGFR-positive glioblastoma cells were treated with indicated drugs;real-time quantitative PCR method was included to detect the TNFα mRNA levels in glioma tissues and cell lines.ELISA was introduced to measure the TNFα protein levels in cell culture supernatant of glioblastoma cells treated with gefitinib.Western blot was used to detect the activity change of intracellular kinases in drug-treated glioblastoma cells.Two mouse xenograft tumor models were carried out to evaluate the in vivo effects of a combination of EGFR and TNFα inhibitors.Results: We found that glioblastoma resistance to gefitinib may be mediated by an adaptive pro-survival TNFα-JNK-Axl signaling axis, and that high TNFα levels in the glioblastoma microenvironment may further intensify primary resistance.A combination of the TNFα-specific small-molecule inhibitor C87 and gefitinib significantly enhanced the sensitivity of glioblastoma cells to gefitinib in vitro and in vivo.Conclusions: Our findings provide a possible explanation for the primary resistance of glioblastoma to EGFR inhibitors and suggest that dual blockade of TNFα and EGFR may be a viable therapeutic strategy for the treatment of patients with chemotherapy-refractory advanced glioblastoma. | Li Ma Chunhua She Qian Shi Qiang Yin Xinxin Ji Yongrong Wang Yulong Fan Xinyao Kong Peng Li Zengfeng Sun Xiaohui Zhang Zhen Zhang Jian Wang Tong Wang Yuanfu Xu Wenliang Li | 2019 | Cancer Biology & Medicine2019，16，3： | 1 |
| 18 | Facile control of surface wettability in TiOJpoly( methyl methacrylate) composite films 显示文摘 | Mengjin anga Zengfeng Di Jung-Kun Lee | 2012 | Journal of Colloid and Interface Science2012，368，： | 1 |
| 19 | Co-alitional games with overlapping coalitions for interfer-ence management in small cell networks 显示文摘 | Zhang Zengfeng Song Lingyang Han Zhu | 2014 | IEEETransactions on Wireless Communications2014，13，5： | 1 |
| 20 | Expression of the Receptor for Type I Insulin-like Growth Factor (IGF1R) in Gastrointestinal Stromal Tumors: An Immunohistochemical Study of 1078 Cases With Diagnostic and Therapeutic Implications显示文摘 | Jerzy Lasota Zengfeng Wang Su Young Kim Lee Helman Markku Miettinen | 2013 | The American Journal of Surgical Pathology2013，，1： | 1 |
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