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| 1 | Two gap-free reference genomes and a global view of the centromere architecture in rice显示文摘Rice(Oryza sativa),a major staple throughout the world and a model system for plant genomics and breeding,was the first crop genome sequenced almost two decades ago.However,reference genomes for all higher organisms to date contain gaps and missing sequences.Here,we report the assembly and analysis of gap-free reference genome sequences for two elite O.sativa xian/indica rice varieties,Zhenshan 97 and Minghui 63,which are being used as a model system for studying heterosis and yield.Gap-free reference genomes provide the opportunity for a global view of the structure and function of centromeres.We show that all rice centromeric regions share conserved centromere-specific satellite motifs with different copy numbers and structures.In addition,the similarity of CentO repeats in the same chromosome is higher than across chromosomes,supporting a model of local expansion and homogenization.Both genomes have over 395 non-TE genes located in centromere regions,of which∼41%are actively transcribed.Two large structural variants at the end of chromosome 11 affect the copy number of resistance genes between the two genomes.The availability of the two gap-free genomes lays a solid foundation for further understanding genome structure and function in plants and breeding climate-resilient varieties. | Jia-Ming Song Wen-Zhao Xie Shuo Wang Yi-Xiong Guo Dal-Hoe Koo Dave Kudrna Chenbo Gong Yicheng Huang Jia-Wu Feng Wenhui Zhang Yong Zhou Andrea Zuccolo Evan Long Seunghee Lee Jayson Talag Run Zhou Xi-Tong Zhu Daojun Yuan Joshua Udall Weibo Xie Rod AWing Qifa Zhang Jesse Poland Jianwei Zhang Ling-Ling Chen | 2021 | Molecular Plant2021，14，10： | 9 |
| 2 | Assessment of the Progress of the Back-Pain Patient显示文摘 | R MILLION W HALL K HAAVIK NILSEN R D BAKER M I V JAYSON | 1982 | Spine1982，，3： | 2 |
| 3 | Light-driven micro-tool equipped with a syringe function显示文摘Leveraging developments in microfabrication open new possibilities for optical manipulation.With the structural design freedom from three-dimensional printing capabilities of two-photon polymerization,we are starting to see the emergence of cleverly shaped‘light robots’or optically actuated micro-tools that closely resemble their macroscopic counterparts in function and sometimes even in form.In this work,we have fabricated a new type of light robot that is capable of loading and unloading cargo using photothermally induced convection currents within the body of the tool.We have demonstrated this using silica and polystyrene beads as cargo.The flow speeds of the cargo during loading and unloading are significantly larger than when using optical forces alone.This new type of light robot presents a mode of material transport that may have a significant impact on targeted drug delivery and nanofluidics injection. | Mark Jayson Villangca Darwin Palima Andrew Rafael Bañas Jesper Glückstad | 2016 | Light(Science & Applications)2016，5，1： | 2 |
| 4 | Ovarian cancer 显示文摘 | JAYSON G C KOHN E C KITCHENER H C | 2014 | Lancet2014，384，9951： | 1 |
| 5 | Hypoxia increases heparanase-dependent tumor cell invasion, which can be inhibit by anti- heparanase antibodies显示文摘 | He X Brenchley PE Jayson GC | 2004 | Cancer Res2004，，11： | 1 |
| 6 | Treatment of cerebral vasospasm with biocompatible controlled-release systems for intracranial drug delivery 显示文摘 | Omeis I Jayson NA Murali R | 2008 | Neurosurgery2008，63，6： | 1 |
| 7 | Thrombocytosis in rheumatoid arthritis 显示文摘 | Hutchinson RM Davis P Jayson MI | 1976 | Ann Rheum Dis1976，35，2： | 1 |
| 8 | Phase I investigation of recombinant anti-human vascular endothelial growth factor antibody in patients with advanced cancer显示文摘 | Jayson GC Mulatero C Ranson M | 2005 | Eur J Cancer2005，41，4： | 1 |
| 9 | Ovarian cancer 显示文摘 | Jayson GC Kohn EC Kitchener HC | 2014 | Lancet2014，384，： | 1 |
| 10 | Increased incidence of serendipitously discovered renal cell carcinoma显示文摘 | Jayson M Sanders H | 1998 | Urology1998，51，： | 1 |
| 11 | Nerve ingrowlh into diseased intervertebral disc in chronic back pain显示文摘 | Freemnnt AJ Peacock TE Goupille P Hoyland JA O'Brien J Jayson MI | 1997 | Lancet1997，350，9072： | 1 |
| 12 | Matrix metalloproteinases:the clue to intervertebral disc degeneration显示文摘 | Goupille P Jayson MI Valat JP | 1998 | Spine1998，23，14： | 1 |
| 13 | Angiogenesis as a target for the treatment of ovarian cancer显示文摘 | SHAW D CLAMP A JAYSON G C | 2013 | Curr Opin Oncol2013，25，5： | 1 |
| 14 | The Current and Future Management of Malignant Ascites显示文摘 | EM Smith GC Jayson | 2003 | Clinical Oncology2003，15，： | 1 |
| 15 | Humic substance uptake by hydrotalcites and PILCs显示文摘 | Amin S Jayson G G | 1996 | Water Research1996，30，2： | 1 |
| 16 | Phase Ⅲ randomized trial of docetaxel-carboplatin versus paclitaxel-carboplatin as first-line chemotherapy for ovarian carcinoma显示文摘 | Vasey PA Jayson GC Gordon A | 2004 | J Natl Cancer Inst2004，96，22： | 1 |
| 17 | The current and future management of malignant ascites显示文摘 | Smith EM Jayson GC | 2003 | Clin Oncol2003，15，2： | 1 |
| 18 | Neck movements in ankylosing spondylitis and their responses to physiotherapy显示文摘 | O'Driscoll SL Jayson MI Baddeley H | 1978 | Ann Rheum Dis1978，37，1： | 1 |
| 19 | PARP inhibitors in BRCA mutation - associated ovarian cancer 显示文摘 | CLAMP A JAYSON G | 2014 | Lancet Oncol2014，349，： | 1 |
| 20 | Phase m randomized trial of docetaxel- carboplatin versus paclitaxel -earboplatin as first line chemotherapy for ovarian carcinoma显示文摘 | Vasey P A Jayson G C Gordon A | 2004 | J Natl Cancer Inst2004，96，22： | 1 |
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