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| 1 | The enhanced X-ray Timing and Polarimetry mission—eXTP显示文摘In this paper we present the enhanced X-ray Timing and Polarimetry mission—eXTP. eXTP is a space science mission designed to study fundamental physics under extreme conditions of density, gravity and magnetism. The mission aims at determining the equation of state of matter at supra-nuclear density, measuring effects of QED, and understanding the dynamics of matter in strong-field gravity. In addition to investigating fundamental physics, eXTP will be a very powerful observatory for astrophysics that will provide observations of unprecedented quality on a variety of galactic and extragalactic objects. In particular, its wide field monitoring capabilities will be highly instrumental to detect the electro-magnetic counterparts of gravitational wave sources.The paper provides a detailed description of:(1) the technological and technical aspects, and the expected performance of the instruments of the scientific payload;(2) the elements and functions of the mission, from the spacecraft to the ground segment. | ShuangNan Zhang Andrea Santangelo Marco Feroci YuPeng Xu FangJun Lu Yong Chen Hua Feng Shu Zhang Sφren Brandt Margarita Hernanz Luca Baldini Enrico Bozzo Riccardo Campana Alessandra De Rosa YongWei Dong Yuri Evangelista Vladimir Karas Norbert Meidinger Aline Meuris Kirpal Nandra Teng Pan Giovanni Pareschi Piotr Orleanski QiuShi Huang Stephane Schanne Giorgia Sironi Daniele Spiga Jiri Svoboda Gianpiero Tagliaferri Christoph Tenzer Andrea Vacchi Silvia Zane Dave Walton ZhanShan Wang Berend Winter Xin Wu Jean J.M.in't Zand Mahdi Ahangarianabhari Giovanni Ambrosi Filippo Ambrosino Marco Barbera Stefano Basso Jörg Bayer Ronaldo Bellazzini Pierluigi Bellutti Bruna Bertucci Giuseppe Bertuccio Giacomo Borghi XueLei Cao Franck Cadoux Francesco Ceraudo TianXiang Chen Yu Peng Chen Jerome Chevenez Marta Civitani Wei Cui WeiWei Cui Thomas Dauser Ettore Del Monte Sergio Di Cosimo Sebastian Diebold Victor Doroshenko Michal Dovciak YuanYuan Du Lorenzo Ducci QingMei Fan Yannick Favre Fabio Fuschino JoséLuis Ga'lvez Min Gao MingYu Ge Olivier Gevin Marco Grassi QuanYing Gu YuDong Gu DaWei Han Bin Hong Wei Hu Long Ji ShuMei Jia WeiChun Jiang Thomas Kennedy Ingo Kreykenbohm Irfan Kuvvetli Claudio Labanti Luca Latronico Gang Li MaoShun Li Xian Li Wei Li ZhengWei Li Olivier Limousin HongWei Liu XiaoJing Liu Bo Lu Tao Luo Daniele Macera Piero Malcovati Adrian Martindale Malgorzata Michalska Bin Meng Massimo Minuti Alfredo Morbidini Fabio Muleri Stephane Paltani Emanuele Perinati Antonino Picciotto Claudio Piemonte JinLu Qu Alexandre Rachevski Irina Rashevskaya Jerome Rodriguez Thomas Schanz ZhengXiang Shen LiZhi Sheng JiangBo Song LiMing Song Carmelo Sgro Liang Sun Ying Tan Phil Uttley Bo Wang DianLong Wang GuoFeng Wang Juan Wang LangPing Wang YuSa Wang Anna L.Watts XiangYang Wen Jörn Wilms ShaoLin Xiong JiaWei Yang Sheng Yang YanJi Yang Nian Yu WenDa Zhang Gianluigi Zampa Nicola Zampa Andrzej A.Zdziarski AiMei Zhang ChengMo Zhang Fan Zhang Long Zhang Tong Zhang Yi Zhang XiaoLi Zhang ZiLiang Zhang BaoSheng Zhao ShiJie Zheng Yu Peng Zhou Nicola Zorzi J.Frans Zwart | 2019 | Science China(Physics,Mechanics & Astronomy)2019，62，2： | 11 |
| 2 | Emerging blood-based biomarkers for detection of gastric cancer显示文摘Early detection and efficient monitoring of tumor dynamics are prerequisites for reducing disease burden and mortality, and for improving the management of patients with gastric cancer(GC). Blood-based biomarker assays for the detection of early-stage GC could be of great relevance both for population-wide or risk groupbased screening programs, while circulating biomarkers that reflect the genetic make-up and dynamics of the tumor would allow monitoring of treatment efficacy, predict recurrences and assess the genetic heterogeneity of the tumor. Recent research to identify blood-based biomarkers of GC has resulted in the identification of a wide variety of cancer-associated molecules, including various proteins, autoantibodies against tumor associated antigens, cell-free DNA fragments, m RNAs and various non-coding RNAs, circulating tumor cells and cancer-derived extracellular vesicles. Each type of these biomarkers provides different information on the disease status, has different advantages and disadvantages, and distinct clinical usefulness. In the current review, we summarize the recent developments in blood-based GC biomarker discovery, discuss the origin of various types of biomarkers and their clinical usefulness and the technological challenges in the development of biomarker assays for clinical use. | Zane Kalnina Irēna Meistere Ilze Kikuste Ivars Tolmanis Pawel Zayakin Aija Linē | 2015 | World Journal of Gastroenterology2015，21，41： | 7 |
| 3 | Advances in Digital Control for High-frequency Switched-mode Power Converters显示文摘Over the last decade,practical digital control of high-frequency switched-mode power converters has moved from proof-of-concept demonstrations to controller chips commercially available from multiple vendors,with applica-tions to point-of-load and isolated DC/DC converters,microprocessor power supplies,power-factor-correction rectifiers,and others.This paper summarizes some of the advances in the area,including approaches to realizations of high-per-formance,high-frequency digital pulse-width modulated(DPWM) controllers,related analysis,modeling and design techniques,as well as performance gains enabled by digital control such as dynamic response and efficiency improve-ments.Examples of experimentally demonstrated results are presented,together with pointers to areas of current and future research and development. | Dragan Maksimovi Regan Zane Luca Corradini | 2010 | 电力电子技术2010，44，12： | 3 |
| 4 | Presence of phthalates in gastrointestinal medications: Is there a hidden danger?显示文摘Pharmaceutical companies that produce gastrointestinal(GI)medications often utilize phthalates for their ability to localize medication release.Commonly prescribed GI medications that may utilize phthalates are 5-Aminosalicylates,proton pump inhibitors,and pancreatic enzymes.Our understanding of the cumulative health effects of phthalates from medications remains unclear,and there is increasing evidence that phthalates are not harmless.Experimental studies in animals have shown that phthalates,specifically dibutyl phthalate and Di-(2-ethyl-hexyl)phthalate,have the potential to alter and/or inhibit reproductive biology and in utero development.Despite the lack of definitive human data,many cohort and cross-sectional studies demonstrate concerning associations between phthalates and poor health status,specifically developmental problems.Longitudinal studies and studies with larger sample sizes are required to determine whether phthalates actually cause negative health consequences.It is also important that physicians regularly review and discuss with patients the medicinal ingredients in their medications and supplements,specifically in pregnant woman with inflammatory bowel disease. | Zane R Gallinger Geoffrey C Nguyen | 2013 | World Journal of Gastroenterology2013，19，41： | 2 |
| 5 | Determination of the chemical diffusion coefficient of lithium in LiFePO4显示文摘 | LISI M ZANE D | 2002 | Solid State Ionics2002，148，： | 1 |
| 6 | Posttraumatic cerebral arterial spasm:transcranial Doppler ultrasound,cerebral blood flow,angiographic findings显示文摘 | Martin NA Doberstein C Zane C | 1992 | J Neurosurgery1992，77，4： | 1 |
| 7 | Determination of the chemical diffusion coefficient of lithium in LiFePO4显示文摘 | Prosini P P Lisi M Zane D | 2002 | Solid State ionics2002，148，： | 1 |
| 8 | Strategies for microsatellite isolation : a review显示文摘 | Bargelloni L Patarnello T | 2002 | Molecular Ecology2002，11，： | 1 |
| 9 | Determination of the chemical diffusion of lithium in LiFePO4 显示文摘 | Prosini P P Lisi M Zane D | 2002 | Solid State l- onics2002，148，12： | 1 |
| 10 | 显示文摘 | Zane D Carewska M Scaccia S | 2004 | Electrochimica Acta2004，49，： | 1 |
| 11 | Valuing moving barrier options显示文摘 | Rogers L C G Zane O | 1997 | Journal of Computational Finance1997，9，： | 1 |
| 12 | Blis- ters on psoriatic lesions treated with TL-01 lamps 显示文摘 | Calzavara Pinton P G Zane C Candiago E | 2000 | Dermatology2000，200，2： | 1 |
| 13 | Strategies for microsatellite isolation: a review显示文摘 | Zane L Barglloni L Patarnello T 2002 | 2002 | Molecular Ecology2002，11，1： | 1 |
| 14 | Strategies for microsatellite isolation:a review显示文摘 | ZANE L BARGELLON L PATARNELLO T | 2002 | Molecular Ecology2002，11，1： | 1 |
| 15 | Strategies for microsateUite isolation: a review 显示文摘 | Zane L Bargelloni L Patarnello T | 2002 | Mol Ecol2002，11，： | 1 |
| 16 | Improved electrochemical performance of a LiFePO4-based composite cathode 显示文摘 | Prosini P P Zane D Pasquali M | 2001 | Electrochem Acta2001，46，： | 1 |
| 17 | Ethnic differences in coping with interpersonal stressors: A Test of Self- Construals as Cultural Mediators显示文摘 | Lam Zane | 2004 | Journal of Cross - Cultural Psychology2004，，4： | 1 |
| 18 | Improved electrochemical performance of a LiFePO4 based composite cathode显示文摘 | Prosini P P Zane D Pasquali M | 2001 | Electrochemica Acta2001，46，23： | 1 |
| 19 | Posttraumatic cerebral arterial spasm:Transcranial Doppler ultrasound,cerebral blood flow,and angiographic findings显示文摘 | Martin NA Doberstein C Zane C | 1992 | J Nearosurgery1992，77，： | 1 |
| 20 | Improved electrochemical performance of a LiFePO4 based composite cathode 显示文摘 | PROSINI P P ZANE D PASQUALI M | 2001 | Electrochemica Acta2001，46，23： | 1 |
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