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| 1 | Immunohistochemical analysis of p53,cyclinD1,RB1,c-fos and N-ras gene expression in hepatocellular carcinoma in Iran显示文摘AIM: To study the effect of some genes especially those involved in cell cycle regulation on hepatocellular carcinoma. METHODS: Paraffin-embedded tissue samples of 25 patients (18 males and 7 females) with hepatocellular carcinoma were collected from 22 pathology centers in Tehran during 2000-2001, and stained using immunohistochemistry method (avidin-biotin-peroxidase) for detection of p53, cyclinD1, RB1, c-fos and N-ras proteins. RESULTS: Six (24%), 5 (20%), 12 (48%) and 2 samples (8%) were positive for p53, cyclinD1, C-fos and N-ras expression, respectively. Twenty-two (88%) samples had alterations in the G1 cell-cycle checkpoint protein expression (RB1 or cyclinD1). P53 positive samples showed a higher (9 times) risk of being positive for RB1 protein than p53 negative samples. Loss of expression of RB1 in association with p53 over-expression was observed in 4 (66.7%) of 6 samples. Loss of expression of RB1 was seen in all cyclinD1 positive, 20 (90.9%) N-ras negative, and 11 (50%) C-fos positive samples, respectively. CyclinD1 positive samples showed a higher (2.85 and 4.75 times) risk of being positive for c-fos and N-ras expression than cyclinD1 negative samples. CONCLUSION: The expression of p53, RB1 and c-fos genes appears to have a key role in the pathogenesis of hepatocellular carcinoma in Iran. Simultaneous overexpression of these genes is significantly associated with their loss of expression during development of hepatocellular carcinoma. | SJ Moghaddam EN Haghighi S Samiee N Shahid AR Keramati S Dadgar MR Zali | 2007 | World Journal of Gastroenterology2007，13，4： | 73 |
| 2 | Hepatocellular carcinoma in Asia: Prevention strategy and planning显示文摘AIM: To review all of epidemiological and etiological aspects of hepatocellular carcinoma(HCC) and examined the prevention of this disease in Asia.METHODS: We conducted a systematic review according to the PRISMA guidelines. We were chosen articles that published previously, from Pub Med(MEDLINE), the Cochrane database and Scopus. The key words used in this research were as follows: HCC in Asia and the way of prevention of this disease, with no language limitations. We selected those papers published before 2014 that we considered to be most important and appropriate. All relevant articles were accessed in full text and all relevant materials was evaluated and reviewed.RESULTS: More than 70% of all new cases of liver cancer were diagnosed in Asia, a region that 75% of all those chronically infected with hepatitis B virus(HBV) in the world. Chronic HBV infection is the main cause of HCC in Asia, where the virus is endemic and vertical transmission is common. Japan, Saudi Arabia, Egypt and Pakistan are exception because of high prevalence of HCV infection in these regions. The prevalence of this cancer is high in Eastern and South-Eastern Asia, But Middle Eastern countries are characterized as moderate prevalence rate of HCC region and Central Asia and some part of Middle Eastern countries are known as low prevalence rate of HCC. In addition of HBV and HCV the other factors such as aflatoxin, alcohol, obesity, diabetes and non-alcoholic fatty liver disease(NAFLD) might be responsible for a low prevalence of HCC in Asian countries. Currently available HCC therapies, chemotherapy, surgical are inefficient, mainly due to usually late diagnosis and high recurrence rates after surgical resection, and usually end with treatment failure. Liver transplantation also remains as a difficult strategy in patients with HCC. Thus prevention of HCC by treating and prevention HBV and HCV infection, the major causative agents of HCC, and the other riskfactors such as aflatoxin, alcohol, obesity, diabetes and NAFLD is of a great medical importance. CONCLUSION: The main challenge which still present in Asia, is the high prevalence of chronic hepatitis.So, prevention of HBV and HCV is the key strategy to reduce the incidence of HCC in Asia. | Sara Ashtari Mohamad Amin Pourhoseingholi Afsaneh Sharifian Mohamad Reza Zali | 2015 | World Journal of Hepatology2015，7，12： | 25 |
| 3 | Clinical features of hepatopulmonary syndrome in cirrhotic patients显示文摘瞄准:评估频率,临床并且帕拉肝肺症候群(HPS ) 并且到的临床的特征在伊朗在病人在这症候群的诊断决定他们的预兆的价值。方法:54 个肝脏硬化症的病人经历了对比由二位心脏病专家检测肺内、心内的分流的提高的回响心动描记法。动脉的血氧, O (2 ) 坡度(A-a ) 和正统说法被气体(ABG ) 测试的动脉的血测量。为 HPS 的诊断标准积极的病人被定义为表明肺内的动脉的膨胀的临床的 HPS 盒子和那些,但是另外的标准(动脉的血血氧不足) 都没被定义为 lHPS 盒子。HPS 频率,敏感,积极、否定的预兆的价值临床并且帕拉临床的特征被学习。结果:十(18.5%) 并且七(13%) 盒子分别地有临床、无临床症状的 HPS。最普通的病原学是肝炎 B。呼吸困难(100%) 和青紫(90%) 是最流行的临床的特征。呼吸困难并且打分别地是最敏感、特定的临床的特征。没有重要关系被发现在之间 HPS 和脾大,腹水,浮肿,黄疸,尿少,和并行的静脉。HPS 在肝炎 B 是更流行的。PaO (2 )<
70 并且动脉牙槽的坡度在 HPS 病人有最高的敏感。正统说法特性是 100% 。结论:与 75% 的否定预兆的价值(NPV ) 与 75% 的积极预兆的价值(PPV ) 和呼吸困难打是在 HPS 的诊断的最好的临床的因素症候群。PaO (2 )<
70 并且 P (A-a ) O (2 )>
30 并且他们的和,是在 HPS 病人的最珍贵的否定、积极的预兆的价值。 | Amir Houshang MohammadAlizadeh Seyed Reza Fatemi Vahid Mirzaee Manoochehr Khoshbaten Bahman Talebipour Afsaneh Sharifian Ziba Khoram Mohammad Reza Zali Farhad Haj-sheikh-oleslami MasoomehGholamreza-shirazi | 2006 | World Journal of Gastroenterology2006，12，12： | 12 |
| 4 | Predictive value and main determinants of abnormal features of intraoperative cholangiography during cholecystectomy显示文摘BACKGROUND:The major issue with intraoperative cholangiography (IOC) is whether its diagnostic accuracy for common bile duct (CBD) stones matches that of other diagnostic procedures,and thus,whether it will become a routine diagnostic procedure.The current study aimed to address the main determinants of CBD stone diagnosis in IOC among an Iranian population.METHODS:In a retrospective review database-based study conducted in Taleghani Hospital in Tehran between 2006 and 2008,baseline data and perioperative information of 2060 patients (male to female ratio 542:1518,mean age 53.7 years) who were candidates for cholecystectomy and underwent concomitant IOC for confirming CBD stones were reviewed.The predictive power of this procedure for diagnosis of abnormal biliary ducts with the focus on biliary stones was determined.RESULTS:Overall mortality and morbidity following cholecystectomy in the study population were 0.6% and 2.6%,respectively.Both early mortality and morbidity due to cholecystectomy were higher in male than female.The prevalence of CBD stones in IOC was 3.4% (5.2% in male and 2.8% in female,P=0.008).Among those without gallstones,8.7% had CBD stones and only 3.1% had concomitant gallstones and CBD stones.The main predictors of stone appearance as an abnormal feature of IOC during cholecystectomy were:advanced age (OR=1.022,P=0.001),male gender (OR=1.498,P=0.050),history of abdominal surgery (OR=1.543,P=0.040) and preoperative endoscopic retrograde cholangiopancreatography (OR=5.400,P<0.001).CONCLUSIONS:IOC is a safe and accurate method for the assessment of bile duct anatomy and stones.Therefore,the routine use of IOC within cholecystectomy seems reasonable and is recommended. | Shahram Yousefpour Azary Heshmat Kalbasi Ali Setayesh Mirhadi Mousavi Asad Hashemi Mahsa Khodadoostan Mohammad Reza Zali Amir Houshang Mohammad Alizadeh | 2011 | Hepatobiliary & Pancreatic Diseases International2011，10，3： | 11 |
| 5 | Non-alcohol fatty liver disease in Asia:Prevention and planning显示文摘AIM:To review all of epidemiological aspects of nonalcoholic fatty liver disease(NAFLD) and also prevent this disease is examined.METHODS:We conducted a systematic review according to the PRISMA guidelines.All searches for writing this review is based on the papers was found in Pub Med(MEDLINE),Cochrane database and Scopus in August and September 2014 for topic of NAFLD in Asia and the way of prevention of this disease,with no language limitations.All relevant articles were accessed in full text and all relevant materials was evaluated and reviewed.RESULTS:NAFLD is the most common liver disorder in worldwide,with an estimated with 20%-30% prevalence in Western countries and 2%-4% worldwide.The prevalence of NAFLD in Asia,depending on location(urban vs rural),gender,ethnicity,and age is variable between 15%-20%.According to the many studies in the world,the relationship between NAFLD,obesity,diabetes mellitus,and metabolic syndrome(MS) is quiet obvious.Prevalence of NAFLD in Asian countries seems to be lower than the Western countries but,it has increased recently due to the rise of obesity,type 2 diabetes and MS in this region.One of the main reasons for the increase in obesity,diabetes and MS in Asia is a lifestyle change and industrialization.Today,NAFLD is recognized as a major chronic liver disease in Asia.Therefore,prevention of this disease in Asian countries is very important and the best strategy for prevention and control of NAFLD is lifestyle modifications.Lifestyle modification programs are typically designed to change bad eating habits and increase physical activity that is associated with clinically significant improvements in obesity,type 2 diabetes and MS.CONCLUSION:Prevention of NAFLD is very importantin Asian countries particularly in Arab countries because of high prevalence of obesity,diabetes and MS. | Sara Ashtari Mohamad Amin Pourhoseingholi Mohamad Reza Zali | 2015 | World Journal of Hepatology2015，7，13： | 10 |
| 6 | Frequent loss of heterozygosity at 8p22 chromosomal region in diffuse type of gastric cancer显示文摘AIM: To study the loss of heterozygosity (LOH) at 8p21-23 locus in diffuse gastric cancer.METHODS: To evaluate the involvement of this region in gastric cancer, we used eight microsatellite markers covering two Mb of mentioned region, to perform a high-resolution analysis of allele loss in 42 cases of late diffuse gastric adenocarcinoma.RESULTS: Six of these STS makers: D8S1149, D8S1645, D8S1643, D8S1508, D8S1591, and D8S1145 showed 36%, 28%, 37%, 41%, 44% and 53% LOH, respectively.CONCLUSION: A critical region of loss, close to the NAT2 locus and relatively far from FEZ1 gene currently postulated as tumor suppressor gene in this region. | Hedayat Allah Hosseini Ali Ahani Hamid Galehdari Ali Mohammad Froughmand Masoud Hosseini Abdolrahim Masjedizadeh Mohammad Reza Zali | 2007 | World Journal of Gastroenterology2007，13，24： | 9 |
| 7 | Intra-familial prevalence of hepatitis B virologic markers in HBsAg positive family members in Nahavand, Iran显示文摘AIM: To determine the prevalence of hepatitis B in Nahavand and evaluate the HBsAg positive prevalence in families with a member who was confirmed to have HBV infection.METHODS: This study was performed in two phases. In the first phase, 1 824 subjects in Nahavand city were selected. The interviewers visited the houses of chosen families to fill the questionnaire and take the blood samples.All subjects signed an informed consent before interviews and blood sampling. The samples were evaluated for HBV virologic markers. In the second phase, 115 HBsAg-positive cases were enrolled and evaluated for HBV virologic markers.RESULTS: The prevalence of positive HBsAg in Nahavand was 2.3%. The most frequent relatives of index cases were sons and daughters (32.2% and 23.5% respectively).Twelve (11%) of all family members were HBsAg positive.Fifty (56.2%) were isolated HBsAb positive and only one person (2.5%) was isolated HBcAb positive. The higher rates of HBsAg marker were detected in the brothers (1-25%) and fathers (1-12.5%). The infection rate in husbands and wives of index cases was 10%. Only two (16.7%) of all HBsAg-positive participants reported previous HBV vaccination.CONCLUSION: The prevalence of intra-familial HBV infection is lower in Nahavand of Iran compared to other studies.More attention should be paid to HBV vaccination and risk-lowering activities. | Amir Houshang Mohammad Alizadeh Mitra Ranjbar Shahin Ansari Seyed Moayed Alavian Hamid Mohaghegh Shalmani Leila Hekmat Mohammad Reza Zali | 2005 | World Journal of Gastroenterology2005，11，31： | 8 |
| 8 | Polyp detection rate and pathological features in patients undergoing a comprehensive colonoscopy screening显示文摘AIM To identify the prevalence, and clinical and pathologic characteristic of colonic polyps among Iranian patients undergoing a comprehensive colonoscopy, and determine the polyp detection rate(PDR) and adenoma detection rate(ADR).METHODS In this cross-sectional study, demographics and epidemiologic characteristics of 531 persons who underwent colonoscopies between 2014 and 2015 at Mehrad gastrointestinal clinic were determined. Demographics, indication for colonoscopy, colonoscopy findings, number of polyps, and histopathological characteristics of the polyps were examined for each person.RESULTS Our sample included 295(55.6%) women and 236(44.4%) men, with a mean age of 50.25 ± 14.89 years. Overall PDR was 23.5%(125/531). ADR and colorectal cancer detection rate in this study were 12.8% and 1.5%, respectively. Polyps were detected more significantly frequently in men than in women(52.8% vs 47.2%, P < 0.05). Polyps can be seen in most patients after the age of 50. The average age of patients with cancer was significantly higher than that of patients with polyps(61.3 years vs 56.4 years, P < 0.05). The majority of the polyps were adenomatous. More than 50% of the polyps were found in the rectosigmoid part of the colon.CONCLUSION The prevalence of polyps and adenomas in this study is less than that reported in the Western populations. In our patients, distal colon is more susceptible to developing polyps and cancer than proximal colon. | Hamid Asadzadeh Aghdaei Ehsan Nazemalhosseini Mojarad Sara Ashtari Mohmad Amin Pourhoseingholi Vahid Chaleshi Fakhrosadat Anaraki Mehrdad Haghazali Mohammad Reza Zali | 2017 | World Journal of Gastrointestinal Pathophysiology2017，8，1： | 6 |
| 9 | CdS/Cu纳米光催化剂降解废水中的HMX和RDX试验研究(英文)显示文摘The wastewater with HMX and RDX was treated by photodegradation process in the presence of cadmium sulfide doped with copper as photocatalyst under UV and Vis irradiations.The influence on the degration of Cu% as dopant in CdS/Cu nanoparticles,pH of solution,dosage of photocatalyst and concentration of explosives were studied.The XRD patterns and UV-Vis spectra were used to characterize the nanoparticle.Results show that the degradation efficiency for HMX and RDX wastewater reaches 85%-88% in the presence of Cd0.95Cu0.05S under 180 min UV irradiation.The dosage of 160.0 mg·L-1 of photocatalyst and the pH of 7 are the optimum.A gradual decrease in degradation at the first two cycles is seen. | Hamid Reza Pouretedal Mohammad Hossien Keshavarz Mohammad Hasan Yosefi Arash Shokrollahi Abbas Zali | 2008 | 含能材料2008，16，6： | 5 |
| 10 | Wet carbon-based solid acid/NaNO_3 as a mild and efficient reagent for nitration of aromatic compound under solvent free conditions显示文摘Nitro aromatic compound can be obtained in high yields via nitration of aromatic compound with wet carbon-based solid acid and NaNO3 under solvent free oxidation at room temperature. | Arash Shokrolahi Abbas Zali Mohammad Hossein Keshavarz | 2007 | Chinese Chemical Letters2007，18，9： | 5 |
| 11 | Helicobacter pylori infection and expression of DNA mismatch repair proteins显示文摘瞄准:为了决定 DNA (MMR ) 蛋白质的表示,包括 hMLH1 和 hMSH2,在在病人与或没有 Helicobacter 的胃的上皮细胞, pylori (H pylori ) 感染了胃炎。方法:五十个 H pylori 积极的病人和 50 H pylori 否定的病人在学习被注册。在有非溃疡消化不良的病人的内视镜检查法期间,二窦和二语料库活体检视为组织学的检查(Giemsa 污点) 并且为免疫被拿 hMLH1 和 hMSH2 的组织化学的染色。结果:为染色的 hMLH1 表明了确实的上皮的房间原子核的百分比是 84.14 +/-7.32% 在 H pylori 否定的病人,当它是 73.34 +/- 时 10.10% 在 H pylori 积极的病人(P <
0.0001 ) 。没有有效差量关于为染色的 hMSH2 表明了确实的上皮的房间原子核的百分比在二个组之间被看见(81.16 +/-8.32% 在 pylori 否定的 H 对 78.24 +/-8.71% 在 H pylori 积极的病人;P = 0.09 ) 。结论:这研究显示 H pylori 可能通过它影响 DNA MMR 系统的能力部分地至少支持胃的癌的开发。 | Vahid Mirzaee Mahsa Molaei Hamid Mohaghegh Shalmani Mohammad Reza Zali | 2008 | World Journal of Gastroenterology2008，14，43： | 5 |
| 12 | Diversity of Helicobacter pylori genotypes in Iranian patients with different gastroduodenal disorders显示文摘AIM:To investigate the diversity of Helicobacter pylori(H.pylori)genotypes and correlations with disease outcomes in an Iranian population with different gastroduodenal disorders.METHODS:Isolates of H.pylori from patients with different gastroduodenal disorders were analyzed after culture and identification by phenotypic and genotypic methods.Genomic DNA was extracted with the QIAamp DNA mini kit(Qiagen,Germany).After DNA extraction,genotyping was done for cagA,vacA(s and m regions),iceA(iceA1,iceA2)and babA with specific primers for each allele using polymerase chain reaction(PCR).All patients’pathologic and clinical data and their relation with known genotypes were analyzed by using SPSS version 19.0 software.2test and Fisher’s exact test were used to assess relationships between categorical variables.The level of statistical significance was set at P<0.05.RESULTS:A total of 71 isolates from 177 patients with different gastroduodenal disorders were obtained.Based on analysis of the cagA gene(positive or negative),vacA s-region(s1or s2),vacA m-region(m1or m2),iceA allelic type(iceA1and iceA2)and babA gene(positive or negative),twenty different genotypic combinations were recognized.The prevalence of cagA,vacA s1,vacA s2,vacA m1,vacA m2,iceA1,iceA2,iceA1+iceA2and babA were 62%,78.9%,19.7%,21.1%,78.9%,15.5%,22.5%,40.8%and 95.8%,respectively.Interestingly,evaluation of PCR results for cagA in 6 patients showed simultaneous existence of cagA variants according to their size diversities that proposed mixed infection in these patients.The most prevalent genotype in cagA-positive isolates was cagA+/vacAs1m2/iceA1+A2/babA+and in cagA-negative isolates was cagA-/vacAs1m2/iceA-/babA+.There were no relationships between the studied genes and histo-pathological findings(H.pylori density,neutrophil activity,lymphoid aggregation in lamina propria and glandular atrophy).The strains which carry cagA,vacAs1/m1,iceA2and babA genes showed significant associations with severe active chronic gastritis(P=0.011,0.025,0.020 and 0.031,respectively).The vacAs1genotype had significant correlation with the presence of the cagA gene(P=0.013).Also,babA genotype showed associations with cagA(P=0.024).In the combined genotypes,only cagA+/vacAs1m1/iceA2/babA+genotype showed correlation with severe active chronic gastritis(P=0.025).CONCLUSION:This genotyping panel can be a useful tool for detection of virulent H.pylori isolates and can provide valuable guidance for prediction of the clinical outcomes. | Farzam Vaziri Shahin Najar Peerayeh Masoud Alebouyeh Tabassom Mirzaei Yoshio Yamaoka Mahsa Molaei Nader Maghsoudi Mohammad Reza Zali | 2013 | World Journal of Gastroenterology2013，19，34： | 5 |
| 13 | Keto-RDX的合成及性能计算(英文)显示文摘Keto-RDX was obtained by one-step method with a certain amount of RDX as by-product.The effects of various parameters on high yield were studied.A simple analytical method was also introduced to determine simultaneously Keto-RDX/RDX mole ratio.Some important theoretical characterizations of Keto-RDX such as detonation performance at maximum nominal density and shock sensitivity were determined by new methods and compared with RDX. | Arash Shokrollahi Abbas Zali Hamid Reza Pouretedal Mohammad Hossein Keshavarz | 2008 | 含能材料2008，16，1： | 4 |
| 14 | 磺化多孔碳和过氧化氢催化氧化有机化合物(英文)显示文摘The oxidation of organic compounds by sulfonated porous carbon and H2O2 was studied at room temperature. Alkyl and aryl sulfides were oxidized to the corresponding sulfoxides or sulfones in excellent yields. Secondary alcohols were also converted to the corresponding esters/lactones and aldehydes to methyl esters in good yields. Moreover,aliphatic tertiary amines and substituted pyridines were oxidized to N-oxides. | Arash SHOKROLAHI Abbas ZALI Mohammad Hossein KESHAVARZ | 2010 | 催化学报2010，31，12： | 4 |
| 15 | 碳基固体酸催化剂上无溶剂条件下酮和芳香醛交叉羟醛缩合反应显示文摘Aromatic aldehydes undergo cross-aldol condensation with ketones in the presence of carbon-based solid acid under solvent-free conditions to afford the corresponding α,β-unsaturated aldol products in excellent yields. The catalyst is reusable several times without any decrease in the yield of the reactions. | Abbas ZALI Kamal GHANI Arash SHOKROLAHI Mohammad Hossein KESHAVARZ | 2008 | 催化学报2008，29，7： | 3 |
| 16 | Improvement of liver function in liver cirrhosis patients after autologous mesenchymal stem cell injection: a phase I–II clinical trial显示文摘 | Pedram Kharaziha Per M. Hellstr?m Babak Noorinayer Farivar Farzaneh Katayoun Aghajani Fereshteh Jafari Mohammad Telkabadi Amir Atashi Maryam Honardoost Mohammad Reza Zali Masoud Soleimani | 2009 | European Journal of Gastroenterology & Hepatology2009，，10： | 3 |
| 17 | Endoscopic retrograde cholangiopancreatography outcome from a single referral center in Iran显示文摘BACKGROUND: Endoscopic retrograde cholangiopancreato- graphy (ERCP) is the first choice for diagnostic evaluation of the pancreatic and biliary tree and can be accompanied by a high diagnostic sensitivity and a poor therapeutic outcome. In the current study, we described our experiences in the indications, findings, and technical success of ERCP in a sample of the Iranian population admitted to a referral center in Iran. METHODS: In a retrospective review database-based study, 780 patients (393 males and 387 females; mean age 57.5 years) who had undergone diagnostic and therapeutic ERCP with the primary diagnosis of hepatobiliary disorder between 2006 and 2008 at Taleghani Hospital in Tehran were reviewed. The key data were demographic characteristics, clinical information, laboratory parameters, as well as post-ERCP complications. RESULTS: A history of cholecystectomy was found in about one-third (36.3%) of participants and 80 (10.3%) out of 780 patients had a previous history of biliary stone. A minority (1.4%) of the patients suffered from hepatobiliary carcinomas, and 11 patients had cirrhosis. The most common clinical manifestations in the patients undergoing diagnostic ERCP were icterus (47.3%), weight loss (31.2%), and dark urine (26.9%). Selective biliary cannulation was technically successful in 87.0% of the patients; however, cannulation failed in 13.0%. The most frequent final diagnosis of ERCP was common bile duct stone that was detected in 40.1% of the patients. The ERCP results in 11.0% of the patients were normal. Regarding appropriate treatment, successful stenting was performed in 43 patients (15.2%). Among post-ERCP complications, pancreatitis was the most adverse event withan incidence rate of 3.3%. Other complications including local bleeding, cholangitis and gastrointestinal perforation, rarely occurred. Post-ERCP pancreatitis was reported in 1.8% of men and 3.6% of women (P=0.120). Pancreatitis was more common in women below 70 years than in those who were older than 70 years (3.6% versus 0.5%; OR: 8.216, P=0.015). This might be due to the more functionally active pancreas in younger women than in the older ones. However, other complications were similar in the two age groups. CONCLUSIONS: Based on our experience, ERCP indications, final diagnosis and related complications are comparatively consistent with those reported in other countries. The most common post-ERCP complication is pancreatitis that is more often observed in younger patients. | Amir H Mohammad Alizadeh Esmaeil S Afzali Mirhadi Mousavi Yaghoub Moaddab Mohammad R Zali | 2010 | Hepatobiliary & Pancreatic Diseases International2010，9，4： | 3 |
| 18 | A Controller-Based Architecture for Information Centric Network Construction and Topology management显示文摘Information-Centric Networking(ICN) has recently emerged as a result of the increased demand to access contents regardless of their location in the network services. This new approach facilitates content distribution as a service of the network with lower delay and higher security in comparison with the current IP network. Applying ICN in current IP infrastructure leads to major complexities. One approach to deploy ICN with less complexity is to integrate ICN with Software Defined Networking(SDN). The SDN controller manages the content distribution, caching, and routing based on the users' requests. In this paper, we extend these context by addressing the ICN topology management problem over the SDN network to achieve an improved user experience as well as network performance. In particular, a centralized controller is designed to construct and manage the ICN overlay. Experimental results indicate that this adopted topology management strategy achieves high performance, in terms of low failure in interest satisfaction and reduced download time compared to a plain ICN. | Zeinab Zali Massoud Reza Hashemi Ilaria Cianci Alfredo Grieco Gennaro Boggia | 2018 | China Communications2018，15，7： | 2 |
| 19 | 内视镜的电子记录: 为改进 colorectal 癌症的管理的一条新途径预防显示文摘 Digestive endoscopy is currently the main diagnostic procedure for investigation of the digestive tract when a digestive disease is suspected.The use of computers and electronic medical records for the management of endoscopic data are an important key to improving endoscopy unit efficiency and productivity.This technology supports optimal program operation,monitoring and evaluation colorectal cancer screening.This article is a comprehensive survey of endoscopic electronic medical records and information systems.Computerized clinical records have the capability of identifying patients due for screening and to calculate baseline rates of colorectal cancer screening by patient characteristics and by primary care physician and practice group.This paper describes data flow in the endoscopy unit,the minimum data set of colorectal cancer and key features of endoscopic electronic medical record.In addition,the researchers state standards in different aspects,especially terminology standards and interoperability standards for image and text. | Elham Maserat Reza Safdari Elnaz Maserat Mohamad Reza Zali | 2012 | World Journal of Gastrointestinal Oncology2012，4，4： | 2 |
| 20 | Colorectal 癌症屏蔽: 在伊朗的行动的时间显示文摘 Colorectal cancer(CRC) is now the third most common cause of cancer-related deaths in the world.According to the Iranian Annual National Cancer Registration Report,CRC is the third most common cancer in Iranian women and fifth in men.The incidence of CRC has increased during the last 25 years.CRC screening is an efficient way to reduce the burden of CRC through detection of precursor lesions of cancer or early stage cancer.Iran may benefit even more from screening programs.According to recent studies,the prevalence of colorectal adenoma in first degree relatives of patients diagnosed with CRC is significantly higher than in the average risk population.So,appropriate screening strategies,especially in relatives of patients,should be considered as the first step of CRC screening in Iran. | Mohamad Amin Pourhoseingholi Mohammad Reza Zali | 2012 | World Journal of Gastrointestinal Oncology2012，4，4： | 2 |
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