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| 1 | Synthesis of Large-Area, Few-Layer Graphene on Iron Foil by Chemical Vapor Deposition显示文摘我们表明一个简单、可控制的方法综合大区域,由优化化学蒸汽免职(CVD ) 的铁底层上的很少层 graphene 用甲烷和氢的混合物的方法。基于 Fe-C 阶段图的分析,为 Fe 表面上的 graphene 的成功的合成的一个合适的过程被设计。适当温度和冷却过程被发现在高度水晶的很少层 graphene 的合成很重要。基于 Graphene 的地效果晶体管(联邦货物税) 设备用产生很少层 graphene 被制作,并且与 3001150 cm2/ 的提取活动性显示出好质量(V 敢椠 ?? 敤瑢吗? | Yunzhou Xue Bin Wu Yunlong Guo Liping Huang Lang Jiang Jianyi Chen Dechao Geng Yunqi Liu Wenping Hu Gui Yu | 2011 | Nano Research2011，4，12： | 7 |
| 2 | Borf-1 protein identified as a transcriptional trans-activator of bovine foamy virus显示文摘Bovine foamy virus (BFV), a member of the spumavirus subfamily of retroviruses,contains two open reading frames (ORF-1 and ORF-2) in addition to the genes coding for gag,po/and env. Borf-1 protein, encoded by BFV ORF-1, is identified as a transcriptional transactivator, which augments gene expression directed by the viral long terminal repeat (LTR).Further investigations in transient expression assays reveal that the Borf-1 responsive elements are located in the U3 domain of the LTR, upstream from position -140 ( + 1 represents the transcription initiation site), and the BFV RU5 region has an inhibitory effect in LTR-directed gene expression. | Jiajian Liu Shuhong Liu Qimin Chen Yunqi Geng | 1999 | Chinese Science Bulletin1999，44，11： | 3 |
| 3 | cis-acting element located in the bovine foamy virus internal promoter possesses the properties of a transcrip-tional enhancer显示文摘Bovine foamy virus encodes a transcriptional transactivitor, Tas or Borf-1, which governs the level of viral transcripts initiated by both the promoter in the long terminal repeat (LTR) and the internal promoter (IP) located in the env gene through their cis-acting targets. We have identified and characterized a 72 bp TBS (Borf-1) responsive element located in BFV3026, internal promoter (TREIP) by deletion mutant and transient expression assay. This cis-acting target element in the internal promoter has the properties of a transcriptional enhancer which functions independently of its orientation, position and also in heterologous promoters (BFV LTR and bovine immunodeficiency virus, BIV LTR). Alignments reveal that there are positional similarity and sequence homology among BFV TREIP, SFV-1 TREIP proximal element and SFV-3 TREIPH, which suggests that this kind of cis-acting elements possesses some common functional character. | Wentao Qiao Chunguang Guo Shuhui Wang Jinzhong Wang Qimin Chen Yunqi Geng | 2002 | Chinese Science Bulletin2002，47，13： | 2 |
| 4 | Characterization of a full-length infectious clone of bovine foamy virus 3026显示文摘The biological features of most foamy viruses(FVs) are poorly understood, including bovine foamy virus(BFV). BFV strain 3026(BFV3026) was isolated from the peripheral blood mononuclear cells of an infected cow in Zhangjiakou, China. A full-length genomic clone of BFV3026 was obtained from BFV3026-infected cells, and it exhibited more than 99% amino acid(AA) homology to another BFV strain isolated in the USA. Upon transfection into fetal canine thymus cells, the full-length BFV3026 clone produced viral structural and auxiliary proteins, typical cytopathic effects, and virus particles. These results demonstrate that the full-length BFV3026 clone is fully infectious and can be used in further BFV3026 research. | Tiejun Bing Hong Yu Yue Li Lei Sun Juan Tan Yunqi Geng Wentao Qiao | 2014 | Virologica Sinica2014，29，2： | 2 |
| 5 | Ultrahigh Density Modulation of Aligned Single-Walled Carbon Nanotube Arrays显示文摘在圣切割石英上控制排列的围单人赛的碳 nanotube 数组(SWNT ) 的密度是在这些材料的各种各样的应用的关键步。然而为调节 SWNT 密度使用的生长机制化学蒸汽免职(CVD ) 方法仍然不好理解,阻止获得需要的结果的有效方法的发展。这里,我们报导完成的一条一般周期的途径超离频圣切割石英 substrateswith 密度上的 SWNT 数组的密度调整用改变 CH4 气体离开时间的一样的催化剂 densitiesby 与常规方法相比到多达 60 次增加了。这条途径对大量起始的催化剂密度,底层,催化剂类型和生长条件适用。我们为与不同的免费的碳集中联系的 SWNT 的催化剂尺寸依赖者成核建议一般机制,它解释所有观察。而且,模型的有效性被在周期的 CVD 途径包含关键参数的变化的系统的实验支持。 | Bin Wu Dechao Geng Yunlong Guo Liping Huang Jianyi Chen Yunzhou Xue Gui Yu Yunqi Liu Hisashi Kajiura Yongming Li | 2011 | Nano Research2011，4，10： | 1 |
| 6 | HIV-1 Vpr activates both canonical and noncanonical NF-κB pathway by enhancing the phosphorylation of IKKα/β显示文摘 | Ruikang Liu Juan Tan Yongquan Lin Rui Jia Wei Yang Chen Liang Yunqi Geng Wentao Qiao | 2013 | Virology2013，，： | 1 |
| 7 | Near‐Equilibrium Chemical Vapor Deposition of High‐Quality Single‐Crystal Graphene Directly on Various Dielectric Substrates显示文摘 | Jianyi Chen Yunlong Guo Lili Jiang Zhiping Xu Liping Huang Yunzhou Xue Dechao Geng Bin Wu Wenping Hu Gui Yu Yunqi Liu | 2014 | Adv. Mater2014，，9： | 1 |
| 8 | Membrane-spanning domain of bovine foamy virus transmembrane protein having cytotoxicity显示文摘Foamy viruses(FVs)have broad cellular tropism infecting vertebrates from fish to human being,which indicates that Env protein has a high capability for membrane fusion.Conservative features in all FV transmembrane(TM)proteins include a region of hydrophobic domain called membrane-spanning domain(MSD),which contains several stretches of hydrophobic amino acids.To investigate whether these features were associated with the cytotoxicity effect of TM on Escherichia coli,a series of mutants were constructed and expressed in the E.coli BL21(DE3)using pET-32a(+)as expressing vector.The results showed that only TM3 without MSD was expressed in E.coli,whereas the other two containing full or part of the MSD(TM1 and TM2)could not be expressed.Furthermore,the bacterial amount and living bacteria analysis revealed that the cytotoxicity of TM was dependent on its MSD,especially on the stretches of hydrophobic amino acids.Western blotting analysis showed that TM3 protein was purified with affinity purification. | MA Yonggang YU Hong WANG Jinzhong CHEN Qimin GENG Yunqi | 2006 | Frontiers in Biology2006，1，4： | 0 |
| 9 | MicroRNAs and their role in viral infection显示文摘Recently,a class of about 22 nucleotides(nt)small RNA has been discovered in many eukaryotes,termed microRNAs(miRNAs),which have a variety of functions.Many recent findings have demonstrated that viruses can also encode their own miRNAs.Meanwhile,other findings reveal a relationship between host miRNA and viral infection.These findings suggest a tight relationship between host and viral infection via miRNA pathway.This article introduces the miRNAs encoded by viruses and reviews the advances of the interaction of the mammalian host miRNAs and viral infection. | MU Junjie YAO Xue CHEN Qimin GENG Yunqi QIAO Wentao | 2007 | Frontiers in Biology2007，2，1： | 0 |
| 10 | Crystal structures of catalytic core domain of BIV integrase: implications for the interaction between integrase and target DNA显示文摘Integrase plays a critical role in the recombination of viral DNA into the host genome.Therefore,over the past decade,it has been a hot target of drug design in the fight against type 1 human immunodeficiency virus(HIV-1).Bovine immunodeficiency virus(BIV)integrase has the same function as HIV-1 integrase.We have determined crystal structures of the BIV integrase catalytic core domain(CCD)in two different crystal forms at a resolution of 2.45Åand 2.2Å,respectively.In crystal form I,BIV integrase CCD forms a back-to-back dimer,in which the two active sites are on opposite sides.This has also been seen in many of the CCD structures of HIV-1 integrase that were determined previously.However,in crystal form II,BIV integrase CCD forms a novel face-toface dimer in which the two active sites are close to each other.Strikingly,the distance separating the two active sites is approximately 20Å,a distance that perfectly matches a 5-base pair interval.Based on these data,we propose a model for the interaction of integrase with its target DNA,which is also supported by many published biochemical data.Our results provide important clues for designing new inhibitors against HIV-1. | Xue Yao Shasha Fang Wentao Qiao Yunqi Geng Yuequan Shen | 2010 | Protein & Cell2010，1，4： | 0 |
| 11 | On the structure of AP-4 responsive element in the LTR of Jembrana disease virus显示文摘Previous studies with deletion and sequence analysis of JDV LTR showed that there is a putative AP-4 responsive element in LTR. By antisense transient assay and gel shifting assay, we for the first time demonstrated that AP-4 modulated JDV gene expression by binding DNA di-rectly to bovine cells. The results, derived from site-directed mutagenesis experiments, suggest that the six base pairs of AP-4 binding site (CAGCTG) have different effects on JDV gene expression. When the first two base pairs changed to GC, JDV gene expression is severely decreased. | Zijing Liu Hongyan Yin Gang Deng Yuhua Yuan Jinzhong Wang Yunqi Geng Qimin Chen | 2003 | Chinese Science Bulletin2003，48，12： | 0 |
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