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| 1 | Novel circular RNA expression profile of uveal melanoma revealed by microarray显示文摘Objective: The present study aimed to investigate circular RNA(circRNA) expression in uveal melanoma(UM).Methods: First,we used microarray to compare the expression profiles of circRNA in five UM samples and five normal uvea tissues.Next,bioinformatics analyses,including gene ontology(GO) analysis and pathway analysis,were applied to study these differentially expressed circRNAs to predict pathogenic pathways that may be involved.Quantitative real-time polymerase chain reaction(qRT-PCR) in 20 UM samples and 20 normal uvea samples was used to confirm the circRNA expression profiles obtained from the microarray data.Finally,we analyzed the interaction between validated circRNAs and their potential cancer-associated miRNA targets.Results: In total,50,579 circRNAs [fold change(FC) ≥2.0; P<0.05],including 20,654 up-regulated and 29,925 down-regulated circRNAs,were identified as differentially expressed between UM tissues and normal uvea tissues.We used qRT-PCR to verify seven dysregulated circRNAs indicated by the microarray data,including hsa_circ_0119873,hsa_circ_0128533,hsa_circ_0047924,hsa_circ_0103232,hsa-circRNA10628-6,hsa_circ_0032148 and hsa_circ_0133460,which may be promising candidates to study future molecular mechanisms.Conclusions: This study explored,for the first time,the abnormal expression of circRNAs in UM and described the expression profile of circRNAs,providing a new potential target for the mechanism of UM and future treatment of UM. | Xuan Yang Yang Li Yueming Liu Xiaolin Xu Yingzhi Wang Yanni Yan Wenjia Zhou Jingyan Yang Wenbin Wei | 2018 | Chinese Journal of Cancer Research2018，30，6： | 6 |
| 2 | Dolomitization by Penesaline Sea Water in Early Cambrian Longwangmiao Formation, Central Sichuan Basin, China显示文摘The Lower Cambrian Longwangmiao Formation shoal dolostone reservoir in Sichuan Basin is currently an exploration and research highlight in China. Reservoir rocks mainly consist of crystalline dolomite with residual grain texture, and dolarenite of which the arene is mainly composed of muddy to micritic dolomite with some crystalline grain directionally aligned. The trace element indicates that the dolomites of Longwangmiao Formation may be related to the high salinity of sea water. The oxygen isotope values of crystalline dolomite and dolarenite are both similar to that of the Early Cambrian marine dolomites, and the carbon isotope values of every kind of dolomites are completely overlapped with that of the seawater in Early Cambrian, indicating the dolomitization fluid is originated from the Early Cambrian sea water. The restricted marine biological communities and a small amount of gypsum pseudonodule seen in muddy to micritic dolomite indicate that the sea water in Early Cambrian was restricted and evaporated. However, the general lack of massive evaporite mineral and gypsum karst breccia indicates that the salinity of sea water during dolomitization was lower than the value of gypsum's precipitation. The Longwangmiao Formation consists of several high-frequency sedimentary cycles, indicating frequent sea level changes. This study indicates that massive dolomitization may also occur in underwater palaeohigh in carbonate platform through the reflux of penesaline sea water driven by a combination of high-and low-frequency sea-level changes. This kind of dolomitization can explain the generation of massive dolomites in the absence of evaporite precipitation, and further indicates that replacement dolomites can be produced by sea water with a wide range of salinity(normal, penesaline to hypersaline). | Xuefei Yang Hao Tang Xingzhi Wang Yaping Wang Yueming Yang | 2017 | Journal of Earth Science2017，28，2： | 6 |
| 3 | Throughput analysis of slotted ALOHA with cooperative transmission using successive interference cancellation显示文摘With a cross-layer design approach, a novel random access protocol is proposed in this paper, which is based on conventional slotted ALOHA (S-ALOHA) using successive interference cancellation (SIC) technique to separate collided packets and cooperative transmission to exploit the physical layer advantages. And a general theoretic analysis model is presented to obtain its throughput, which is also suitable for analyzing the performance of other protocols (such as S-ALOHA and S-ALOHA with cooperative transmission (C-ALOHA)) and is shown to be right and effective. Numerical results demonstrate that the proposed protocol can improve the maximal throughput by 190% and 132% over a Rayleigh fading channel, respectively, as compared with S-ALOHA and C-ALOHA. And the results show that our protocol can provide an effective random access method with high throughput for wireless transmission. | HU YingBo YANG WeiWei CAI YueMing | 2009 | Science in China(Series F)2009，52，12： | 6 |
| 4 | Preparation and application of ZnO doped Pt-CeO2 nanofibers as electrocatalyst for methanol electro-oxidation显示文摘ZnO doped Pt/CeO_2 nanocomposites were prepared by electrospinning and reduction impregnation.Xray diffraction(XRD),transmission electron microscopy(TEM),energy disperse spectroscopy(EDS) and X-ray photoelectron spectroscopy(XPS) were employed to characterize the nanocomposites.It is observed that ZnO and CeO_2 form the hexagonal wurtzite phase and cubic fluorite phase in the nanocomposite,respectively,whilst Pt nanoparticles(NPs) with the number-averaged size of ca.3.1 nm are uniformly distributed on the surface of nanofibers.The mass fraction of Pt NPs in the nanocomposites is about 10 wt%.The doping of ZnO is effective to promote reactive oxygen species,surface reaction sites and the interaction between Pt and oxides.The catalytic performance of nanocomposites was evaluated by the methanol electro-oxidation.indexed with the catalytic activity,stability of catalyst.As a result,it is found that the nanocomposite exhibits much higher activity and stability for methanol oxidation than the undoped Pt/CeO_2 catalyst. | Yingping Zheng Xin Zhang Zhengying Zhang Ying Li Yueming Sun Yongbing Lou Xiaojun Li Yang Lu | 2018 | Journal of Rare Earths2018，36，9： | 5 |
| 5 | Aquaculture area extraction and vulnerability assessment in Sanduao based on richer convolutional features network model显示文摘Sanduao is an important sea-breeding bay in Fujian,South China and holds a high economic status in aquaculture.Quickly and accurately obtaining information including the distribution area,quantity,and aquaculture area is important for breeding area planning,production value estimation,ecological survey,and storm surge prevention.However,as the aquaculture area expands,the seawater background becomes increasingly complex and spectral characteristics differ dramatically,making it difficult to determine the aquaculture area.In this study,we used a high-resolution remote-sensing satellite GF-2 image to introduce a deep-learning Richer Convolutional Features(RCF)network model to extract the aquaculture area.Then we used the density of aquaculture as an assessment index to assess the vulnerability of aquaculture areas in Sanduao.The results demonstrate that this method does not require land and water separation of the area in advance,and good extraction can be achieved in the areas with more sediment and waves,with an extraction accuracy>93%,which is suitable for large-scale aquaculture area extraction.Vulnerability assessment results indicate that the density of aquaculture in the eastern part of Sanduao is considerably high,reaching a higher vulnerability level than other parts. | LIU Yueming YANG Xiaomei WANG Zhihua LU Chen LI Zhi YANG Fengshuo | 2019 | Journal of Oceanology and Limnology2019，37，6： | 4 |
| 6 | Coupling of Hierarchical Al_(2)O_(3)/TiO_(2) Nanofibers into 3D Photothermal Aerogels Toward Simultaneous Water Evaporation and Purification显示文摘Serious freshwater shortage and environmental pollution boost the rapid development of solar-driven water production.Although improved evaporation rate has achieved in recent years,undesirable impurity(e.g.,pollutant components)can also be inevitably evaporated and collected as impurity in produced freshwater.This work reports new ultra-light three-dimensional(3D)aerogels assembled by hierarchical Al_(2)O_(3)/TiO_(2) nanofibers and reduced graphene oxide(RGO)for excit-ing synchronized solar-driven evaporation and water purification.Hydrophilic Al_(2)O_(3)/TiO_(2) fibrous channels linked up the graphene hot-spots and water body for sufficient water supply and bulk water insulation.Meanwhile,featured with thermal insulation effect,the Al_(2)O_(3)/TiO_(2) nanofibers effectively locked the converted heat with less energy loss from sunlight.The introducing of Al_(2)O_(3)/TiO_(2) nanofibers into RGO aerogel led to the effective interfacial evaporation for a more rapid water evaporation rate(2.19 kg·m−2·h−1,normalized to evaporation area including both top and side surface),which was 36%higher than that of pristine RGO aerogel.Moreover,simultaneous with the strong steam generation,Al_(2)O_(3)/TiO_(2) nanofibers in situ removed the pollutants within steam by photodegradation,achieving polluted wastewater purification with high con-taminant removal ratio of 91.3%.Our work on coupling Al_(2)O_(3)/TiO_(2) nanofibers into photothermal aerogel provides attractive solutions for the challenges of clean water scarcity and serious environmental pollution. | Xiangyu Meng Wanlin Xu Zhihui Li Jianhui Yang Jingwu Zhao Xixi Zou Yueming Sun Yunqian Dai | 2020 | Advanced Fiber Materials2020，2，2： | 4 |
| 7 | A COLLABORATIVE SPECTRUM SENSING SCHEME USING FUZZY COMPREHENSIVE EVALUATION IN COGNITIVE RADIO显示文摘Cognitive Radio(CR) is a promising technology to solve the challenging spectrum scarcity problem.However, to implement CR, spectrum sensing is the groundwork and the precondition.In this paper, a collaborative spectrum sensing scheme using fuzzy comprehensive evaluation is proposed.The final sensing decision of the proposed scheme is based on the combination of distributed sensing results of different Secondary Users(SUs).To improve the reliability of the sensing decision, the combination procedure takes into account the credibility of each SU, which is evaluated using fuzzy comprehensive evaluation.The effect of the presence of malicious SUs and malfunctioning SUs on the performance of the proposed scheme is also investigated.The efficiency of the scheme is validated through analysis and simulation. | Yang Wendong Ye Yuhuang Cai Yueming Xu Youyun | 2009 | Journal of Electronics(China)2009，26，3： | 3 |
| 8 | SHP2 regulates skeletal cell fate by modifying SOX9 expression and transcriptional activity显示文摘Chondrocytes and osteoblasts differentiate from a common mesenchymal precursor, the osteochondroprogenitor(OCP), and help build the vertebrate skeleton. The signaling pathways that control lineage commitment for OCPs are incompletely understood. We asked whether the ubiquitously expressed protein-tyrosine phosphatase SHP2(encoded by Ptpn11) affects skeletal lineage commitment by conditionally deleting Ptpn11 in mouse limb and head mesenchyme using 'Cre-lox P'-mediated gene excision.SHP2-deficient mice have increased cartilage mass and deficient ossification, suggesting that SHP2-deficient OCPs become chondrocytes and not osteoblasts. Consistent with these observations, the expression of the master chondrogenic transcription factor SOX9 and its target genes Acan, Col2a1, and Col10a1 were increased in SHP2-deficient chondrocytes, as revealed by gene expression arrays, q RT-PCR, in situ hybridization, and immunostaining. Mechanistic studies demonstrate that SHP2 regulates OCP fate determination via the phosphorylation and SUMOylation of SOX9, mediated at least in part via the PKA signaling pathway. Our data indicate that SHP2 is critical for skeletal cell lineage differentiation and could thus be a pharmacologic target for bone and cartilage regeneration. | Chunlin Zuo Lijun Wang Raghavendra M.Kamalesh Margot E.Bowen Douglas C.Moore Mark S.Dooner Anthony M.Reginato Qian Wu Christoph Schorl Yueming Song Matthew L.Warman Benjamin G.Neel Michael G.Ehrlich Wentian Yang | 2018 | Bone Research2018，6，2： | 3 |
| 9 | Object-based classification of cloudy coastal areas using medium-resolution optical and SAR images for vulnerability assessment of marine disaster显示文摘Efficient and accurate access to coastal land cover information is of great significance for marine disaster prevention and mitigation.Although the popular and common sensors of land resource satellites provide free and valuable images to map the land cover,coastal areas often encounter significant cloud cover,especially in tropical areas,which makes the classification in those areas non-ideal.To solve this problem,we proposed a framework of combining medium-resolution optical images and synthetic aperture radar(SAR)data with the recently popular object-based image analysis(OBIA)method and used the Landsat Operational Land Imager(OLI)and Phased Array type L-band Synthetic Aperture Radar(PALSAR)images acquired in Singapore in 2017 as a case study.We designed experiments to confirm two critical factors of this framework:one is the segmentation scale that determines the average object size,and the other is the classification feature.Accuracy assessments of the land cover indicated that the optimal segmentation scale was between 40 and 80,and the features of the combination of OLI and SAR resulted in higher accuracy than any individual features,especially in areas with cloud cover.Based on the land cover generated by this framework,we assessed the vulnerability of the marine disasters of Singapore in 2008 and 2017 and found that the high-vulnerability areas mainly located in the southeast and increased by 118.97 km2 over the past decade.To clarify the disaster response plan for different geographical environments,we classified risk based on altitude and distance from shore.The newly increased high-vulnerability regions within 4 km offshore and below 30 m above sea level are at high risk;these regions may need to focus on strengthening disaster prevention construction.This study serves as a typical example of using remote sensing techniques for the vulnerability assessment of marine disasters,especially those in cloudy coastal areas. | YANG Fengshuo YANG Xiaomei WANG Zhihua LU Chen LI Zhi LIU Yueming | 2019 | Journal of Oceanology and Limnology2019，37，6： | 2 |
| 10 | Distributed space-time-frequency coding for cooperative OFDM systems显示文摘A distributed space-time-frequency (STF) coding scheme is proposed for cooperative OFDM (C-OFDM) systems with three terminals over quasi-static frequency-selective Rayleigh fading channels. The outage probability is derived and its tight closed-form lower bound is presented. Asymptotic analysis indicates that the proposed scheme can achieve both spatial and multipath (frequency) diversity. The theoretical analysis of the proposed STF coded scheme is further implemented by the distributed group STF block coding (D-GSTFBC) scheme based on the subcarrier grouping technique. Simulation results confirm the previously introduced theoretical analysis. | YANG WeiWei CAI YueMing WANG Lei | 2009 | Science in China(Series F)2009，52，12： | 2 |
| 11 | Amino acid composition, molecular weight distribution and antioxidant activity of protein hydrolysates of soy sauce lees显示文摘 | Bao Yang Hongshun Yang Jing Li Zhenxing Li Yueming Jiang | 2010 | Food Chemistry2010，，2： | 2 |
| 12 | Retinol-binding protein 4 as a risk factor for cholesterol gallstone formation显示文摘 | Tao Han Diancai Zhang Zan Fu Yueming Sun Wei Yang Cuimei Yuan | 2013 | Molecular and Cellular Biochemistry2013，，1： | 2 |
| 13 | On the Performance of the Block - Based Selective OFDM Decode - and - Forward Relaying Scheme for 4G Mobile Communication Systes显示文摘 | Yueming Cai Wendong Yang | 2011 | Journal of communications and networks2011，，1： | 1 |
| 14 | Screening of High Temperature Resistant Fodder Yeast Strains显示文摘[Objective] This study aimed to screen yeast strains suitable for high temperature processing of formulated biological feed. [Method] High temperature resistance and culture conditions of six yeast strains were investigated. [Result] Two yeast strains resistant to high temperature( 45 ℃) with high viable cell number( 108 cells / ml) were screened,including DQFC2117-1 and DQFC2122-2. [Conclusion] Strains DQFC2117-1 and DQFC2122-2 could be used as high temperature resistant yeast strains for processing of formulated biological feed. | Yufeng LIU Yueming WANG Qingli YANG Yanru JI Yan DONG Jie SHI | 2015 | Agricultural Biotechnology2015，4，4： | 1 |
| 15 | β-Aminobutyric acid induces resistance of mango fruit to postharvest anthracnose caused by Colletotrichum gloeosporioides and enhances activity of fruit defense mechanisms显示文摘 | Zhengke Zhang Dongping Yang Bo Yang Zhaoyin Gao Min Li Yueming Jiang Meijiao Hu | 2013 | Scientia Horticulturae2013，，： | 1 |
| 16 | N-acetylcys- teine improves pancreatic microcirculation and alleviates the severity of acute necrotizing pancreatitis 显示文摘 | DU Bingqing YANG Yueming CHEN Yonghua | 2013 | Gut and Liver2013，7，3： | 1 |
| 17 | Ultra-high pressure treatment effects on polysaccharides and lignins of longan fruit pericarp显示文摘 | Bao Yang Yueming Jiang Rui Wang | 2009 | Food Chemistry2009，112，2： | 1 |
| 18 | Effects of ultrasonic extraction on the physical and chemical properties of polysaccharides from longan fruit pericarp显示文摘 | Bao Yang Yueming Jiang Mourning Zhao | 2008 | Polymer Degradation and Stability2008，93，1： | 1 |
| 19 | Effects of ultrasonic extraction on the physical and zhemical properties of polysaccharides from longan fruit pericarp 显示文摘 | Yang Bao Jiang Yueming Zhao Mourning | 2008 | Polymer Degradation and Stability2008，3，： | 1 |
| 20 | Identification of polyphenols in tobacco leaf and their antioxidant and antimicrobial activities显示文摘 | Haiyan Wang Mouming Zhao Bao Yang Yueming Jiang Guohua Rao | 2007 | Food Chemistry2007，，4： | 1 |
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