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| 1 | Relationship Between Microcystin in Drinking Water and Colorectal Cancer显示文摘Objective To investigate the association of microcystin (MC) in drinking water with the incidence of colorectal cancer. Methods The study was designed as a retrospective cohort. Eight townships or towns were randomly selected as the study sites in Haining City of Zhejiang Province, China. 408 cases of colon and rectum carcinomas diagnosed from 1977 to 1996 in the study sites were included, and a survey on types of drinking water of these patients was conducted. Samples of different water sources (well, tap, river and pond) were collected separately and microcystin concentrations were determined by indirect competitive ELISA method. Results The incidence rate of colorectal cancer was significantly higher in population who drank river and pond water than those who drank well and tap water. Compared to well water, the relative risk (RR) for colorectal cancer was 1.88 (tap), 7.94 (river) and 7.70 (pond) respectively. The positive rate (>50 pg/mL) of microcystin in samples of well, tap, river and pond water was 0, 0, 36.23% and 17.14% respectively. The concentration of microcystin in river and pond water was significantly higher than that in well and tap water (P<0.01). Spearman rank correlation analysis showed that in the study sites, the microcystin concentration of river and pond water was positively associated with the incidence of colorectal cancer (rs= 0.881, P<0.01). Conclusions The types of drinking water are positively associated with the incidence of colorectal cancer in the study sites, and this may be related to microcystin contamination of drinking water. Further biological study is needed to support the possible causative role of mycrocystin in carcinogenesis of colon and rectum. | ZhouL YuH 等 | 2002 | Biomedical and Environmental Sciences2002，15，2： | 23 |
| 2 | Sequential versus triple therapy for the first-line treatment of Helicobacter pylori : a multicentre, open-label, randomised trial显示文摘 | Jyh-Ming Liou Chieh-Chang Chen Mei-Jyh Chen Chien-Chuan Chen Chi-Yang Chang Yu-Jen Fang Ji–Yuh Lee Shih-Jer Hsu Jiing-Chyuan Luo Wen-Hsiung Chang Yao-Chun Hsu Cheng-Hao Tseng Ping-Huei Tseng Hsiu-Po Wang Ueng-Cheng Yang Chia-Tung Shun Jaw-Town Lin Yi-Chia | 2012 | The Lancet2012，，： | 13 |
| 3 | Evaluation of remediation process with soapberry derived saponin for removal of heavy metals from contaminated soils in Hai-Pu, Taiwan显示文摘The use of a biodegradable natural plant-based surfactant extracted from soapberry is proposed for the remediation of Ni,Cr and Mn from industrial soil site in Hai-Pu,Taiwan.Batch experiments were performed under variation of fundamental factors(saponin concentration,pH,and incubation time) for metal remediation.Removal of Ni and Mn were increased with increasing saponin concentration(0.015-0.150 g/L),whereas the removal of Cr was increased upto 0.075 g/L saponin.The Ni,Cr and Mn were removed significantly(p ≤ 0.05) at near to the neutral and slightly acidic(pH 5 to 8) conditions.Removal efficiency of Ni(99%) from the soil was found to be greater than that of Cr(73%) or Mn(25%) in the presence of saponin at a concentration of 0.150 g/L at pH 5.The removal percentage increased with incubation time where the removal of Ni was faster than that of Cr and Mn.The result indicates the feasibility of eco-friendly removal of heavy metal(Ni,Cr and Mn) from industrial soil by soil washing process in presence of plant derived saponin. | Jyoti Prakash Maity Yuh Ming Huang Cheng-Wei Fan Chien-Cheng Chen Chun-Yi Li Chun-Mei Hsu Young-Fo Chang Ching-I Wu Chen-Yen Chen Jiin-Shuh Jean | 2013 | Journal of Environmental Sciences2013，25，6： | 11 |
| 4 | 混合现实技术在口腔颌面部肿瘤手术中的应用显示文摘目的:探讨混合现实技术在口腔颌面部肿瘤手术中的应用价值。方法:选择2018年12月—2020年1月就诊于北京大学口腔医院口腔颌面外科需行手术治疗的肿瘤患者,将患者术前增强CT原始数据导入星图医学影像工作站(维卓致远,中国北京),分别对肿瘤、血管、骨骼等重要解剖结构进行三维模型重构,显示其术前空间关系,对重点结构进行标记,并进行术前规划。通过混合现实技术在术区立体显示三维重建模型,术者利用简单手势在术中保持无菌状态下对眼前的三维重建模型进行调整,观察肿瘤范围、大小、位置及其与周围临近重要解剖结构的关系。应用混合现实技术辅助手术进行,手术开始前进行三维模型配准,肿瘤显露过程中进行术中验证,术后利用Likert量表对混合现实技术的应用效果进行评价。结果:入选的8例患者均顺利实施了混合现实技术辅助下的肿瘤切除手术,手术过程中三维重建模型平均配准时间为12.0 min,术者在所有病例的手术中均都能直观、立体地观看肿物以及周围解剖结构的三维重建模型,并可在术中自行调整图像。Likert量表评价结果显示:在感知准确性、帮助确定解剖部位、术中图像引导作用,以及改善手术安全性的潜力方面均获得较高评分(分别为4.22、4.19、4.16和4.28分)。8例患者术后愈合良好,无手术并发症发生。结论:混合现实技术能通过三维重建模型实时立体可视化,提供术区解剖结构信息,引导和修正手术操作,提高口腔颌面部肿瘤切除手术的准确性和安全性。 | 唐祖南 Hui Yuh Soh 胡耒豪 于尧 章文博 彭歆 | 2020 | 北京大学学报(医学版)2020，52，6： | 9 |
| 5 | 湍流模化的现状及发展趋势显示文摘本文讨论了湍流模化研究的发展现状,提出了今后湍流模式的可能改进途径。根据一组湍流封闭假定得到了各种2阶湍流模式,如Reynolds应力模式(RSM),代数应力模式(k-ε-A)及涡粘性模式(k-ε-E)。以自由剪切流、空腔流及通过偏心槽的流动为例作出了预报。虽然至今还不存在一个完备湍流模式,但2阶湍流模式已经具备了某些预报能力。湍流模化的不完备性可能要归咎于各向同性耗散和单湍流尺度等假定的不适当。利用多重湍流尺度概念,包括利用湍流涡的分维,可以改善湍流的预报。 | 陈景仁 Sheng Yuh Jaw 胡晓强 赵渭军 | 1992 | 力学进展1992，22，3： | 8 |
| 6 | Corruption of coronary collateral growth in metabolic syndrome: Role of oxidative stress显示文摘The myocardium adapts to ischemic insults in a variety of ways.One adaptation is the phenomenon of acute preconditioning,which can greatly ameliorate ischemic damage.However,this effect wanes within a few hours and does not confer chronic protection.A more chronic adaptation is the so-called second window of preconditioning,which enables protection for a few days.The most potent adaptation invoked by the myocardium to minimize the effects of ischemia is the growth of blood vessels in the heart,angiogenesis and arteriogenesis (collateral growth),which prevent the development of ischemia by enabling flow to a jeopardized region of the heart.This brief review examines the mechanisms underlying angiogenesis and arteriogenesis in the heart.The concept of a redox window,which is an optimal redox state for vascular growth,is discussed along with signaling mechanisms invoked by reactive oxygen species that are stimulated during ischemia-reperfusion.Finally,the review discusses of some of the pathologies,especially the metabolic syndrome,that negatively affect collateral growth through the corruption of redox signaling processes. | Yuh Fen Pung William M Chilian | 2010 | World Journal of Cardiology2010，2，12： | 5 |
| 7 | Risk of complications and urinary incontinence following cytoreductive prostatectomy: a multi-institutional study显示文摘当时,新兴的证据建议了 cytoreductive 前列腺切除术(CRP ) 允许优异 oncologic 控制与照顾雄激素剥夺标准的电流相比治疗独自一个。然而,在变形前列腺癌症(mPCa ) 的 cytoreduction 的安全和利益没被证明。因此,我们评估了在最新与 mPCa 诊断的人跟随 CRP 的复杂并发症的发生。在四个第三级的外科的中心从 2006 ~ 2014 经历了 CRP 的 68 个病人的一个总数与为临床上局部性的前列腺癌症(PCa ) 经历了激进的前列腺切除术的 598 个人相比。尿不能自制被定义为任何垫的使用。CRP 有更长起作用的时间(200 min 对 140 min, P < 0.0001 ) 并且更高估计的血损失(250 ml 对 125 ml, P < 0.0001 ) 与控制组相比。然而,外套(8.82% 对 5.85%) 和主要复杂并发症率(4.41% 对 2.17%) 在二个组之间是可比较的。重要地,尿不能自制率在在外科以后 1 年在 CRP 组是显著地更高的(57.4% 对 90.8% , P < 0.0001 ) 。Univariate 逻辑分析证明估计的血损失在 unadjusted 模型两个都是 perioperative 复杂并发症的唯一的独立预言者(或:1.18;95% CI:1.02-1.37;P = 0.025 ) 并且外科调整类型的模型(或:1.17;95% CI:1.01-1.36;P = 0.034 ) 。在结论, CRP 比激进的前列腺切除术更挑战性、与尿不能自制的尤其是更高的发生联系。不过, CRP 是为选择谁的 PCa 病人的一个技术上可行、安全的手术与节点积极或多骨的转移在场当由富有经验的外科医生表现了时。未来的、多机构的临床的试用当前是在进行之中的验证这个概念。 | Dae Keun Kim Jaspreet Singh Parihar Young Suk Kwon Sinae Kim Brian Shinder Nara Lee Nicholas Farber Thomas Ahlering Douglas Skarecky Bertram Yuh Nora Ruel Wun-lae Kim Koon Ho Rha Isaac Yi Kim | 2018 | Asian Journal of Andrology2018，20，1： | 5 |
| 8 | Language Anxiety: Differentiating Writing and Speaking Components显示文摘 | Yuh‐showCheng Elaine K.Horwitz Diane L.Schallert | 2008 | Language Learning2008，，3： | 5 |
| 9 | 开窗畸形之基底动脉并发颅内多发性动脉瘤显示文摘 | 李文彬 李明华 H Grady Daniel Dee H Wu L.Tytle Rifat Karatas Yasemin Karatas William TC Yuh | 2003 | 实用放射学杂志2003，19，9： | 4 |
| 10 | Conversion of Human Umbilical Cord Mesenchymal Stem Cells in Wharton’s Jelly to Dopaminergic Neurons In Vitro: Potential Therapeutic Application for Parkinsonism显示文摘 | Yu‐ShowFu Yun‐ChihCheng Maan‐Yuh AnyaLin HenrichCheng Pei‐MingChu Shih‐ChichChou Yang‐HsinShih Miau‐HwaKo Min‐ShanSung | 2009 | STEM CELLS2009，，1： | 3 |
| 11 | Clinical Features of Sudden Sensorineural Hearing Loss in Diabetic Patients显示文摘 | Shuen‐FuWeng Yuh‐ShyangChen Chuan‐JenHsu Fen‐YuTseng | 2009 | The Laryngoscope2009，，9： | 2 |
| 12 | 固定化酵母细胞酱油发酵工艺的改进显示文摘采用圆柱形丝状陶瓷两段式生物反应器,分别固定鲁氏酵母和球拟酵母发酵酱油的工艺.使发酵时间缩短到八天.由于制备和掌握圆柱形丝状陶瓷生物反应器是相当麻烦的,所以,对于中试规模生产酱油来说更便利的陶瓷球则是合乎要求的生物反应器.为解决上述困难,我们应用陶瓷球代替圆柱形丝状陶瓷生物反应器.把鲁氏酵母细胞和球拟酵母细胞分别固定在用陶瓷球制作的两段式生物反应器上,酱油发酵则需要八天.已有酵母固定在颗粒状陶瓷载体上连续酿造啤酒的报导. | HiroyukiHORITSU Min Yuh WANG Keiichi KAWAI 江清彦 | 1992 | 生物技术1992，2，4： | 2 |
| 13 | Removal of Cu, Pb and Zn by foam fractionation and a soil washing process from contaminated industrial soils using soapberry-derived saponin: A comparative effectiveness assessment显示文摘 | Jyoti Prakash Maity Yuh Ming Huang Chun-Mei Hsu Ching-I Wu Chien-Cheng Chen Chun-Yi Li Jiin-Shuh Jean Young-Fo Chang Chen-Yen Chen | 2013 | Chemosphere2013，，10： | 2 |
| 14 | Design and Control of Autonomous Underwater Robots: A Survey显示文摘 | J. Yuh | 2000 | Autonomous Robots2000，，1： | 2 |
| 15 | Tumor size evaluated by pelvic examination compared with 3-D MR quantitative analysis in the prediction of outcome for cervical cancer 显示文摘 | Mayr NA Yuh WT Zheng J | 1997 | Int J Radiat Oncol Biol Phys1997，39，： | 2 |
| 16 | Androgen Receptor Is a New Potential Therapeutic Target for the Treatment of Hepatocellular Carcinoma显示文摘 | Weng–Lung Ma Cheng–Lung Hsu Ming–Heng Wu Chun–Te Wu Cheng–Chia Wu Jiann–Jyh Lai Yuh–Shan Jou Chun–Wei Chen Shuyuan Yeh Chawnshang Chang | 2008 | Gastroenterology2008，，3： | 2 |
| 17 | Underwater autonomous manipulation for intervention missions AUVs 显示文摘 | Marani G Choi S K Yuh J | 2009 | Ocean Engineering2009，36，1： | 1 |
| 18 | Development of a real-time control architecture for a semi-autonomous underwater vehicle for intervention missions显示文摘 | Kim T W Yuh J | 2004 | Control Engineering Practice2004，12，12： | 1 |
| 19 | How to Say No: an Analysis of Cross - cultural Difference and Pragmatic Transfer 显示文摘 | Yuh - Fang Chang | 2009 | Language Sciences2009，，4： | 1 |
| 20 | The physicochemical/electrochemical properties of binary Ni-Co oxides显示文摘 | Hu Chi Chang Lee Yuh Shu Wen Ten Chin | 1997 | Materials Chemistry and Physics1997，48，3： | 1 |
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