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| 1 | Differential diagnosis of left-sided abdominal pain:Primary epiploic appendagitis vs colonic diverticulitis显示文摘AIM:To investigate the clinical characteristics of left primary epiploic appendagitis and to compare them with those of left colonic diverticulitis.METHODS:We retrospectively reviewed the clinical records and radiologic images of the patients who presented with left-sided acute abdominal pain and had computer tomography(CT) performed at the time of presentation showing radiological signs of left primary epiploic appendagitis(PEA) or left acute colonic diverticulitis(ACD) between January 2001 and December 2011. A total of 53 consecutive patients were enrolled and evaluated. We also compared the clinical characteristics,laboratory findings,treatments,and clinical results of left PEA with those of left ACD.RESULTS:Twenty-eight patients and twenty-five patients were diagnosed with symptomatic left PEA and ACD,respectively. The patients with left PEA had focal abdominal tenderness on the left lower quadrant(82.1%). On CT examination,most(89.3%) of the patients with left PEA were found to have an oval fatty mass with a hyperattenuated ring sign. In cases of left ACD,the patients presented with a more diffuse abdominal tenderness throughout the left side(52.0%vs 14.3%; P = 0.003). The patients with left ACD had fever and rebound tenderness more often than those with left PEA(40.0% vs 7.1%,P = 0.004; 52.0% vs14.3%,P = 0.003,respectively). Laboratory abnormalities such as leukocytosis were also more frequently observed in left ACD(52.0% vs 15.4%,P = 0.006).CONCLUSION:If patients have left-sided localized abdominal pain without associated symptoms or laboratory abnormalities,clinicians should suspect the diagnosis of PEA and consider a CT scan. | Jeong Ah Hwang Sun Moon Kim Hyun Jung Song Yu Mi Lee Kyung Min Moon Chang Gi Moon Hoon Sup Koo Kyung Ho Song Yong Seok Kim Tae Hee Lee Kyu Chan Huh Young Woo Choi Young Woo Kang Woo Suk Chung | 2013 | World Journal of Gastroenterology2013，19，40： | 6 |
| 2 | Effects of feeding a diet containing Gymnema sylvestre extract: attenuating progression of obesity in C57BL/6J mice显示文摘Objective: To investigate the effect of Gymnema sylvestre extract(GS) on initial anti-obesity, liver injury, and glucose homeostasis induced by a high-fat diet(HFD). Methods: The dry powder of GS was extracted with methanol, and gymnemic acid was identified by high performance liquid chromatography as deacyl gymnemic acid. Male C57BL/6J mice that fed on either a normal diet, normal diet containing 1 g/kg GS(CON+GS) HFD, or HFD containing 1.0 g/kg GS(HFD+GS) for 4 weeks were used to test the initial anti-obesity effect of GS. Body weight gain and food intake, and serum levels about lipid and liver injury markers were measured. Histopathology of adipose tissue and liver stained with hematoxylin and eosin(H&E) and oil-red O were analyzed. After 4 weeks of GS extract feeding, intraperitoneal glucose tolerance test(IPGTT) was performed. Results: The methanol extracts of GS exerted significant anti-obesity effects in HFD+GS group. They decreased body weight gain, a lower food and energy efficiency ratio, and showed lower serum levels of total cholesterol(TC), triglyceride(TG), low-density lipoprotein(LDL)-cholesterol, very-low density lipoprotein(VLDL)-cholesterol and leptin compared with the HFD group. The decreases of abdominal as well as epididymal fat weight and adipocyte hypertrophy, lipid droplets in liver, and serum levels of aspartate aminotransferase(AST) and alanine transaminase(ALT) were also observed. The CON+GS group showed an effect of glucose homeostasis compared to the CON group. Conclusions: This study shows that GS provide the possibility as a key role in an initial anti-obesity effects feeding with a HFD. | Hyeon-Jeong Kim Seong-Ho Hong Seung-Hee Chang Sanghwa Kim Ah Young Lee Yoonjeong Jang Orkhonselenge Davaadamdin Kyeong-Nam Yu Ji-Eun Kim Myung-Haing Cho | 2016 | Asian Pacific Journal of Tropical Medicine2016，9，5： | 3 |
| 3 | Prognostic value of alcohol consumptionand some other dietary habits for survival in a cohort of Chinese men with lung cancer显示文摘Background:Alcohol consumption and some other dietary habits are thought to be associated with lung cancer incidence.However,the effects of these habits on lung cancer prognosis have been studied rarely.The purpose of this study was to address these gaps in knowledge.Methods:We studied a cohort of 1052 Chinese men in Hong Kong who were diagnosed with primary lung cancer.Cox proportional hazards models were used to determine the prognostic values of consumption of alcohol,fresh fruits or vegetables,meat,and fried or preserved food.Results:Compared with never drinkers,men who drank alcohol 1-3 days per week had a more favorable lung cancer prognosis(hazard ratio[HR]:0.82,95%confidence interval[CI]0.68-0.97);however,this survival advantage was not significant in men who drank alcohol more frequently(HR:0.91,95%CI 0.73-1.14).Compared with men who consumed preserved or fried food only occasionally,men who consumed these foods frequently had a higher risk of lung cancer mortality(HR:1.20,95%CI 1.00-1.42).Conclusions:Occasional consumption of alcohol was a favorable survival factor for Chinese men with lung cancer.However,this survival benefit did not exist for frequent drinkers of alcohol.Chinese men with lung cancer who were frequent consumers of fried or preserved food had a worse prognosis than those who consumed these foods only occasionally. | Wentao Li Lap Ah Tse Joseph S.K.Au Kai Shing Yu Feng Wang Ignatius Tak-sun Yu | 2017 | Chinese Journal of Cancer2017，36，7： | 3 |
| 4 | The protective effect of quercetin against oxidative stress in the human RPE in vitro显示文摘 | Kook D Wolf AH Yu AL | 2008 | Invest Ophthalmol Vis Sci2008，49，4： | 1 |
| 5 | S-nitrosylation of cyclin-depend-ent kinase 5(cdk5)regulates its kinase activity and dendrite growthduring neuronal development显示文摘 | Zhang P Yu PC Tsang AH | 2010 | J Neurosci2010，30，14： | 1 |
| 6 | Usefulness of continuous renal replacement therapy for correcting hypernatremia in a patient with severe congestive heart failure显示文摘 | Hoon Suk Park Yu Ah Hong Hyun Gyung Kim Sun Ryoung Choi In O. Sun Byung Ha Chung Cheol Whee Park Chul Woo Yang Yong Soo Kim Bum Soon Choi | 2012 | Hemodial Int2012，，4： | 1 |
| 7 | Connective tissue growth factor induces extracellular matrix deposition in human trabecular meshwork cells显示文摘 | Junglas B Yu AH Welge-Lüssen U | 2009 | Exp Eye Res2009，88，6： | 1 |
| 8 | Personal and family history of lung disease as risk factors for adenocarcinoma of the lung显示文摘 | Wu AH Yu MC Thomas DC | 1988 | Cancer Res1988，48，： | 1 |
| 9 | Dietary patterns and breast cancer risk in Asian American women 显示文摘 | Wu AH Yu MC Tseng CC | 2009 | Am J Clin Nutr2009，89，4： | 1 |
| 10 | Electrical and Thermal Characterization of a Dielectrophoretic Chip with 3D Electrodes for Cells Manipulation显示文摘 | Francis Tay E H Liming Yu Ah Ju Pang Ciprian Iliescu | 2007 | Electrochimica Acta2007，52，： | 1 |
| 11 | Comparison of contrast en- hanced ultrasound and contrast enhanced CT or MRI in monitoring percutaneous thermal ablation procedure in patients with hepatocellular carcinoma: a multi-center study in China显示文摘 | Lu MD Yu XL Li AH | 2007 | Ultrasound Med Biol2007，33，11： | 1 |
| 12 | Mode of transmission of Legionella pnumophila显示文摘 | Muder RR Yu VL Woo AH | 1986 | Arch Intern Med1986，146，8： | 1 |
| 13 | Celecoxib radiosensitizes the human cervical cancer HeLa cell line via a mechanism dependent on reduced cyclo - oxygenase - 2 and vascular endothelial growth factor C expression 显示文摘 | Wang AH Tian XY Yu JJ | 2012 | J Int Med Res2012，40，1： | 1 |
| 14 | Comparison of contrast enhanced ultrasound and contrast enhanced CT or MRI in monitoring percutaneous thermal ablation procedure in patients with hepatocellular carcinoma:a multi-eenter study in China显示文摘 | Lu MD Yu XL Li AH | | 0，，11： | 1 |
| 15 | Bone morphogenetic protein-7 is an antagonist of transforming growth factor-beta2 in human trabecular meshwork cells 显示文摘 | Fuchshofer R Yu AH Welge-Lussen U | 2007 | Invest Oph- thalmol Vis Sci2007，48，2： | 1 |
| 16 | Pneumocystis carinii induces ICAM-1 expression in lung epithelial cells through a TNF-alpha- mediated mechanism 显示文摘 | Yu ML Limper AH | 1997 | Am J Physiol1997，273，61： | 1 |
| 17 | Endothelial expression of E-selectin is induced by the platelet-specifie chemokine platelet factor 4 through LRP in an NF-kappaB-dependent manner显示文摘 | Yu G Rux AH Ma P | 2005 | Blood JT2005，105，9： | 1 |
| 18 | Celecoxib radiosensitizes the human cervical cancer HeLa cell line via a mechanism dependent on reduced cyclo-oxygenase-2 and vascular endothelial growth factor C expression显示文摘 | Wang AH Tian XY Yu J J | 2012 | J Int Med Res2012，40，1： | 1 |
| 19 | Green tea and risk of breast cancer in Asian Americans显示文摘 | Wu AH Yu MC Tseng CC | 2003 | Int J Cancer2003，106，4： | 1 |
| 20 | Plasma isoflavone levels versus self-reported soy isoflavone levels in Asian-American women in Los Angeles County 显示文摘 | Wu AH Yu MC Tseng CC | 2004 | Carcinogenesis2004，25，1： | 1 |
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