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| 1 | A randomized controlled trial comparing open vs laparoscopy-assisted distal gastrectomy for the treatment of early gastric cancer: An interim report显示文摘 | Seigo Kitano Norio Shiraishi Kyuzo Fujii Kazuhiro Yasuda Masafumi Inomata Yosuke Adachi | 2002 | Surgery2002，，1： | 4 |
| 2 | Protective effects of silybin and analogues against X-ray radiation-induced damage显示文摘Silybin (SLB ) 和类似的类似物,也就是 hesperetin (HESP ) , naringenin (NAN ) 和 naringin (NAR ) ,被相信是为某些癌症作为 chemopreventive 代理人被报导了的自然 flavonoids 的活跃成分。而且, SLB 和类似物被决定了快由脉搏 radiolysis 技术从氧化损坏修理 DNA 底。现在的学习被设计评估 SLB 的保护的效果,软 X-ray-induced 上的类似物在 vitro 损坏 DNA 到 plasmid。DNA 损坏被 agarose 胶化电气泳动决定。SLB 和类似物被发现在 micromolar 集中保护 DNA 免受放射损坏的伤害。在测试的混合物之中, HESP 和 SLB 在阻止 DNA 单个海滨的裂缝(SSB ) 的 X-ray-induced 形成是最有效的。有另外的实验的这些结果的比较证明 SLB 和类似物的能力与混合物的能力相关在 vitro 禁止 DNA 损坏清除自由激进分子。我们的工作表明自然 flavonoids, SLB 和类似物可以对放射损坏被用作有势力辐射防护药物。 | Haiying Fu Mingzhang Lin Yosuke Katsumura Akinari Yokoya Kuniki Hata Yusa Muroya Kentaro Fujii Naoya Shikazono | 2010 | Acta Biochimica et Biophysica Sinica2010，42，7： | 4 |
| 3 | Accumulation of Somatic Mutations in TP53 in Gastric Epithelium with Helicobacter pylori infection显示文摘 | Takahiro Shimizu Hiroyuki Marusawa Yuko Matsumoto Tadashi Inuzuka Atsuyuki Ikeda Yosuke Fujii Sachiko Minamiguchi Shin’ichi Miyamoto Tadayuki Kou Yoshiharu Sakai Jean E. Crabtree Tsutomu Chiba | 2014 | Gastroenterology2014，，： | 2 |
| 4 | Endoscopic mucosal resection vs endoscopic submucosal dissection for superficial non-ampullary duodenal tumors显示文摘BACKGROUND The selection of endoscopic treatments for superficial non-ampullary duodenal epithelial tumors(SNADETs)is controversial.AIM To compare the efficacy and safety of endoscopic mucosal resection(EMR)and endoscopic submucosal dissection(ESD)for SNADETs.METHODS We retrospectively analyzed the data of patients with SNADETs from a database of endoscopic treatment for SNADETs,which included eight hospitals in Fukuoka,Japan,between April 2001 and October 2017.A total of 142 patients with SNADETs treated with EMR or ESD were analyzed.Propensity score matching was performed to adjust for the differences in the patient characteristics between the two groups.We analyzed the treatment outcomes,including the rates of en bloc/complete resection,procedure time,adverse event rate,hospital stay,and local or metastatic recurrence.RESULTS Twenty-eight pairs of patients were created.The characteristics of patients between the two groups were similar after matching.The EMR group had a significantly shorter procedure time and hospital stay than those of the ESD group[median procedure time(interquartile range):6(3-10.75)min vs 87.5(68.5-136.5)min,P<0.001,hospital stay:8(6-10.75)d vs 11(8.25-14.75)d,P=0.006].Other outcomes were not significantly different between the two groups(en bloc resection rate:82.1%vs 92.9%,P=0.42;complete resection rate:71.4%vs 89.3%,P=0.18;and adverse event rate:3.6%vs 17.9%,P=0.19,local recurrence rate:3.6%vs 0%,P=1;metastatic recurrence rate:0%in both).Only one patient in the ESD group underwent emergency surgery owing to intraoperative perforation.CONCLUSION EMR has significantly shorter procedure time and hospital stay than ESD,and provides acceptable curability and safety compared to ESD.Accordingly,EMR for SNADETs is associated with lower medical costs. | Mitsuru Esaki Kazuhiro Haraguchi Kazuya Akahoshi Naru Tomoeda Akira Aso Soichi Itaba Haruei Ogino Yusuke Kitagawa Hiroyuki Fujii Kazuhiko Nakamura Masaru Kubokawa Naohiko Harada Yosuke Minoda Sho Suzuki Eikichi Ihara Yoshihiro Ogawa | 2020 | World Journal of Gastrointestinal Oncology2020，12，8： | 2 |
| 5 | High-temperature formation phases and crystal structure of hot-pressed thermoelectric compounds with chalcopyrite-type structure显示文摘In this study, we introduced the temperaturedependent formation phases and crystallographic parameters of hot-pressed silver gallium telluride AgGaTe_2 and copper gallium telluride CuGaTe_2 with chalcopyrite structure from 300 to 800 K. These two compounds are potential thermoelectric materials in the intermediate temperature range; however, the temperature-dependent formation phases and crystallographic parameters of hotpressed samples have not yet been analyzed in detail. The crystal structure analysis based on synchrotron X-ray diffraction(SXRD) measurements clarifies that impurity phases such as Te and Ag_2 Te in the AgGaTe_2 matrix and Te and CuTe in the CuGaTe_2 matrix appear at some temperature regions above 300 K. The existence of such impurity phases could be correlated with the increases of the electrical resistivity and Seebeck coefficient of the samples after multiple measurement cycles of the temperature-dependent transport properties from 300 to 800 K.The tetragonal lattice parameters a and c, tetragonal lattice volume, thermal expansion coefficients, tetragonal distortion, anion displacement parameter, and isotropic displacement parameter of the hot-pressed AgGaTe_2 and CuGaTe_2 were also analyzed. These crystallographic parameters are expected to substantially affect the thermoelectric properties of AgGaTe_2 and CuGaTe_2. Our results provide prospect of the long-term high-temperature stability and clues of the detailed analysis on the transport properties of hot-pressed AgGaTe_2 and CuGaTe_2, which should aid their development for thermoelectric applications. | Atsuko Kosuga Yosuke Fujii Akito Horie | 2018 | Rare Metals2018，37，4： | 2 |
| 6 | Evaluation of the lateral sentinel node by indocyanine green for rectalcancer based on micrometastasis determined by reverse transcriptase-polymerasechain reaction显示文摘 | Shingo Noura Masayuki Ohue Yosuke Seki Takashi Yamamoto Atsushi Idota Junko Fujii Tomoyuki Yamasaki Hiromu Nakajima Kohei Murata Masao Kameyama Terumasa Yamada Isao Miyashiro Hiroaki Ohigashi Masahiko Yano Osamu Ishikawa Shingi Imaoka | 2008 | Oncology Reports2008，，4： | 1 |
| 7 | Produc- tion of dimethyl ether and hydrogen by methanol reform- ing for an HCCI engine system with waste heat recovery- Continuous control of fuel ignitability and utilization of exhaust gas heat 显示文摘 | Toshio Shudo Yosuke Shima Tatsuya Fujii | 2009 | International Journal of Hydrogen Energy2009，34，18： | 1 |
| 8 | Endoscopic Features of Sessile Serrated Adenomas/Polyps Using Narrow-Band Imaging with Optical Magnification显示文摘 | Masayoshi Yamada Taku Sakamoto Yosuke Otake Takeshi Nakajima Aya Kuchiba Hirokazu Taniguchi Shigeki Sekine Ryoji Kushima Hemchand Ramberan Adolfo Parra-Blanco Takahiro Fujii Takahisa Matsuda Yutaka Saito | 2014 | Gastrointestinal Endoscopy2014，，： | 1 |
| 9 | Effect of Gravity on Arc Shape in GTA Welding-for Low Electric Arc Current显示文摘Gas tungsten arc (GTA) welding was performed both in a microgravity environment and in a terrestrial environment,and the arc shapes in both environments were compared. A microgravity condition was obtained using the free fallsystem at the Japan Microgravity Center. The system can maintain a 10 s microgravity of less than 10-5 g. Awater-cooled Cu plate was used to simplify the arc phenomenon. The electric arc current was between 15 and 80 A,and the shielding and atmospheric gas was 99.9995% Ar and its flowing rate was 10 l/min. The polarity was a directcurrent electrode negative (DCEN). The arc gap was 3 mm and careful attention was also paid to the arc gap in boththe terrestrial and microgravity environments being the same. As a result, it was found that no effect of gravity onthe arc shape is observed under general welding conditions (over 60 A). When the electric arc current is lower than25 A, the arc shape is determined by the initial position of the arc root and is constant with time. Accordingly, itcan not be judged whether or not the arc shape is affected by gravity for this range. When the electric arc current isbetween 25 A and 60 A, it is estimated that the arc shape is not affected by gravity though it is occasionally affectedby other minor effects. | Hidetoshi FUJII Yosuke SUMI Manabu TANAKA Kiyoshi NOGI | 2003 | Journal of Materials Science & Technology2003，19，z1： | 0 |
| 10 | Efficacy of hybrid endoscopic submucosal dissection with SOUTEN in gastric lesions:An ex vivo porcine model basic study显示文摘BACKGROUND Hybrid endoscopic submucosal dissection(ESD)that comprises mucosal incision and partial submucosal dissection followed by snaring in a planned manner,has been developed for endoscopic resection of gastrointestinal neoplasms to overcome the technical barrier of ESD.Although the superiority of hybrid ESD with SOUTEN,a single multifunctional device,over conventional ESD has been indicated,the actual effect of snaring itself remains unclear since SOUTEN could be applied to hybrid ESD group,but not to the conventional ESD group,due to ethical issue in clinical practice.AIM To determine whether and how hybrid ESD was superior to conventional ESD in the endoscopic treatment of gastric lesions in an ex vivo porcine model basic study.METHODS Sixteen endoscopists participated in this basic study in August 2020 at Kyushu University,performing 32 procedures each for hybrid ESD and conventional ESD.Mock lesions(10-15 mm,diameter)were created in the porcine stomach.The primary outcome was total procedure time and secondary outcomes were en bloc or complete resection,perforation,procedure time/speed for both,mucosal incision,and submucosal dissection.Factors associated with difficulty in ESD including longer procedure time,incomplete resection,and perforation,were also investigated.Categorical and continuous data were analyzed using the chi-square test or Fisher’s exact test and the Mann-Whitney U test,respectively.RESULTS The median total procedure time of hybrid ESD was significantly shorter than that of conventional ESD(median:8.3 min vs 16.2 min,P<0.001).Time,speed,and the amount of hyaluronic acid during submucosal dissection were more favorable in hybrid ESD than conventional ESD(time,5.2 min vs 10.4 min,P<0.001;speed,43.7 mm^(2)/min vs 23.8 mm^(2)/min,P<0.00;injection volume,1.5 mL vs 3.0 mL,P<0.001),although no significant differences in those factors were observed between both groups during mucosal incision.There was also no significant difference between both groups in the en bloc/complete resection rate and perforation rate(complete resection,93.8%vs 87.5%,P=0.67;perforation,0% vs 3.1%,P=1).Selection of conventional ESD as the treatment method was significantly associated with difficulties during ESD(odds ratio=10.2;highest among factors).CONCLUSION Hybrid ESD with SOUTEN improves the treatment outcomes of gastric lesions.It also has the potential to reduce medical costs since SOUTEN is a single multifunctional device that is inexpensive. | Mitsuru Esaki Eikichi Ihara Norikazu Hashimoto Shuichi Abe Chihoko Aratono Noriko Shiga Yorinobu Sumida Hiroyuki Fujii Kazuhiro Haraguchi Shunsuke Takahashi Tsutomu Iwasa Kayoko Nakano Masafumi Wada Shinichi Somada Kei Nishioka Yosuke Minoda Haruei Ogino Yoshihiro Ogawa | 2021 | World Journal of Gastrointestinal Surgery2021，13，6： | 0 |
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