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| 1 | The Genesis Mechanism of the Mantle Fluid Action and Evolution in the Ore-Forming Process: A Case Study of the Laowangzhai Gold Deposit in Yunnan, China显示文摘Based on petrological studies of the wall rocks, mineralizing rocks, ores and veins from the Laowangzhai gold deposit, it is discovered that along with the development of silication, carbonation and sulfidation, a kind of black opaque ultra-microlite material runs through the spaces between grains, fissures and cleavages. Under observations of the electron microprobe, scanning electronic microscopy and energy spectrum, this kind of ultra-microlite material is confirmed to consist of ultra microcrystalline quartz, silicate, sulfides and carbonates, as well as rutile, scheelite and specularite (magnetite), showing characters of liquation by the analyses of SEM and energy spectrum. The coexistence of immiscibility and precipitating co-crystallization strongly suggests that the mineralizing fluid changed from the melt to the hydrothermal fluid. Combined with the element geochemical researches, it is realized that the ultra-microlite aggregate is the direct relics of the mantle fluid behaving like a melt and supercritical fluid, which goes along with the mantle-derived magma and will escape from the magma body at a proper time. During the alteration process, the nature of the mantle fluid changed and it is mixed with the crustal fluid, which are favorable for mineralization in the Loawangzhai gold deposit. | LIU Xianfan LI Chunhui LU Qiuxia DENG Biping SONG Xiangfeng ZHAO Fufeng CHU Yating XIAO Jixiong YI Liwen HUANG Yupeng | 2012 | Acta Geologica Sinica(English Edition)2012，86，3： | 13 |
| 2 | Cold Stress-induced Glucosyltransferase CsUGT78A15 is Involved in the Formation of Eugenol Glucoside in Camellia sinensis显示文摘Eugenol is a natural phenolic compound known for its health-promoting properties and its ability to add a floral scent to tea plants.Plant eugenol glycosides have been identified and shown to make important contributions to fruit floral quality.However,the details of their biosynthesis and metabolism in tea plants are still unknown.Here,eugenol glucoside was unambiguously identified as a native metabolite in the tea plant,and its biosynthesis was shown to be induced by low temperature treatment.Through the analysis of UGTs induced by low temperature,the glycosyltransferase CsUGT78A15 was identified in tea,and its encoded protein was shown to catalyze the glucosylation of eugenol.Vmax/Km ratios showed that eugenol was the most suitable substrate for CsUGT78A15.Sugar donor preference analysis showed that CsUGT78A15 had a higher selectivity for glucose,followed by galactose and glucuronic acid.The expression of CsUGT78A15was correlatedwith the accumulation of eugenol glucoside in different tissues and genotypes of tea.Down-regulation of CsUGT78A15 led to a decreased eugenol glucoside content under cold stress,indicating that CsUGT78A15 plays an important role in the biosynthesis of eugenol glucoside under cold stress.The identification of eugenol glucoside in the tea plant and the discovery of a cold stress-induced eugenol glucosyltransferase in tea provide the foundation for the improvement of tea flavor under cold stress and the biotechnological production of eugenol glucoside. | Mingyue Zhao Binbin Cai Jieyang Jin Na Zhang Tingting Jing Jingming Wang Yuting Pan Zixiang Zhou Yifan Zhao Yingying Feng Feng Yu Mengting Zhang Yating Li Zhonghua Liu Chuankui Song | 2020 | Horticultural Plant Journal2020，6，6： | 4 |
| 3 | Antibacterial Effects of Chinese Herbal Medicines against Streptococcus iniae in Oreochromis niloticus显示文摘In this study,the antibacterial effects of Chinese herbal medicines against Streptococcus iniae in Oreochromis niloticus were investigated by drug sensitivity test. The results indicated that Streptococcus iniae was extremely sensitive to Galla Chinensis,Fructus Hippophae and Fructus Mume,highly sensitive to Sappan Lignum,Pericarpium Granati,Folium Eucalypti and Radix Scutellariae,moderately sensitive to Rhizoma Coptidis,Radix et Rhizoma Rhei,Flos Caryophyllata,Cortex phellodendri and Rabdosia serra( Maxim.) Hara,and insensitive to Herba Portulacae,Herba Houttuyniae,Polygonum hydropiper L.,Herba Menthae,Radix Glycyrrhizae,Pericarpium Citri Reticulatae,Herba Andrographitis and Rhizoma Acori Tatarinowii. Chinese medicinal herbs which Streptococcus iniae was extremely sensitive or moderately sensitive to were selected and prepared into three Chinese herbal medicine formulae for medicated bath of Oreochromis niloticus infected artificially with Streptococcus iniae. The results showed that medicated bath elicited therapeutic effects on infected Oreochromis niloticus. Formula II exhibited the best therapeutic effect with an effective percentage of 90%. | Guisheng GAO Yanying ZHANG Yongmei SU Qiumei SHI Guangping GAO Yating BAI Hongsheng HAN Jianxin ZHU Qingchun SONG Guanglian REN | 2016 | Agricultural Biotechnology2016，5，1： | 2 |
| 4 | The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients 显示文摘 | YATES C R ZHANG W SONG P | 2003 | J Clin Pharmacol2003，43，6： | 1 |
| 5 | The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients显示文摘 | Yates CR Zhang WH Song PF | 2003 | J Clin Pharmacol2003，43，6： | 1 |
| 6 | The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients 显示文摘 | Yates CR Zhang W Song P etal | 2003 | J Clin Pharmacol2003，，： | 1 |
| 7 | Improving accuracy of canopy hemispherical photography by a constant threshold value derived from an unobscured overcast sky显示文摘 | Song G Z M Doley D Yates D | 2013 | Canadian Journal of Forest Research2013，44，1： | 1 |
| 8 | The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients显示文摘 | Yates CR Zhang WH Song PF | 2003 | J Clin Pharmacol2003，43，： | 1 |
| 9 | Real-time PCR-based genotyping assay for CXCR2 polymorphisms 显示文摘 | GUPTA M SONG P YATES CR | 2004 | Clin Chim Acta2004，341，12： | 1 |
| 10 | Investigating the Changes in Air Pollutant Emissions over the Beijing-Tianjin-Hebei Region in February from 2014 to 2019 through an Inverse Emission Method显示文摘In recent years,China has implemented several measures to improve air quality.The Beijing-Tianjin-Hebei(BTH)region is one area that has suffered from the most serious air pollution in China and has undergone huge changes in air quality in the past few years.How to scientifically assess these change processes remain the key issue in further improving the air quality over this region in the future.To evaluate the changes in major air pollutant emissions over this region,this paper employs ensemble Kalman filtering(EnKF)for integrating the national ground monitoring pollutant observation data and the Nested Air Quality Prediction Modeling System(NAQPMS)simulation data to inversely estimate the emission rates of SO_(2),NOX,CO,and primary PM_(2.5)over BTH region in February from 2014 to 2019.The results show that SO_(2),NOX,CO,and primary PM_(2.5)emissions in the BTH region decreased in February from 2014 to 2019 by 83%,37%,41%,and 42%,while decreases in Beijing during this period were 86%,67%,59%,and 65%,respectively.Compared with the prior emission inventory,the inversion emission inventory reduces the uncertainty of multi-pollutant simulation in the BTH region,with simulated root mean square errors of the monthly average concentrations of SO_(2),NOX,PM_(2.5),and CO reduced by 41%,30%,31%,and 22%,respectively.The average uncertainties of SO_(2),NOX,PM_(2.5),and CO inversion emissions in2014-19 are±14.03%yr^(-1),±28.91%yr^(-1),±126.15%yr^(-1),and±43.58%yr^(-1).Compared with the uncertainty of MEIC emission,the uncertainties of all species changed by+2%yr^(-1),-2%yr^(-1),-26%yr^(-1),and-4%yr^(-1),respectively.The spatial distribution results illustrate that air pollutant emissions are mainly distributed over the eastern and southern BTH regions.The spatial gap between the inversion emissions and MEIC emissions was further closed in 2019 compared to 2014.The results of this paper can provide a new reference for assessing changes in air pollution emissions over the BTH region in recent years and validating a bottom-up emission inventory. | Xuechun LUO Xiao TANG Haoyue WANG Lei KONG Huangjian WU Weiguo WANG Yating SONG Hongyan LUO Yao WANG Jiang ZHU Zifa WANG | 2023 | Advances in Atmospheric Sciences2023，40，4： | 1 |
| 11 | The effect of CYP3A5 and MDRI polymorphic expression on cyclosporine oral disposition in renal transplant patients显示文摘 | YATES C R ZHANG W SONG P et ai | 2003 | J Clin Pharmacol2003，43，6： | 1 |
| 12 | The Impact of the Numbers of Monitoring Stations on the National and Regional Air Quality Assessment in China During 2013-18显示文摘China national air quality monitoring network has become the core data source for air quality assessment and management in China.However,during network construction,the significant change in numbers of monitoring sites with time is easily ignored,which brings uncertainty to air quality assessments.This study aims to analyze the impact of change in numbers of stations on national and regional air quality assessments in China during 2013-18.The results indicate that the change in numbers of stations has different impacts on fine particulate matter(PM_(2.5))and ozone concentration assessments.The increasing number of sites makes the estimated national and regional PM_(2.5) concentration slightly lower by 0.6−2.2μg m^(−3) and 1.4−6.0μg m^(−3) respectively from 2013 to 2018.The main reason is that over time,the monitoring network expands from the urban centers to the suburban areas with low population densities and pollutant emissions.For ozone,the increasing number of stations affects the long-term trends of the estimated concentration,especially the national trends,which changed from a slight upward trend to a downward trend in 2014−15.Besides,the impact of the increasing number of sites on ozone assessment exhibits a seasonal difference at the 0.05 significance level in that the added sites make the estimated concentration higher in winter and lower in summer.These results suggest that the change in numbers of monitoring sites is an important uncertainty factor in national and regional air quality assessments,that needs to be considered in long-term concentration assessment,trend analysis,and trend driving force analysis. | Hongyan LUO Xiao TANG Huangjian WU Lei KONG Qian WU Kai CAO Yating SONG Xuechun LUO Yao WANG Jiang ZHU Zifa WANG | 2022 | Advances in Atmospheric Sciences2022，39，10： | 1 |
| 13 | The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients显示文摘 | Yates CR Zhang W Song P | 2003 | J Clin Pharmacol2003，43，6： | 1 |
| 14 | The effect of CYP3A5 and MDR1 polymorphic expression on cyclosporine oral disposition in renal transplant patients 显示文摘 | Yates C R Zhang W Song P | 2003 | J Clin Pharmacol2003，43，6： | 1 |
| 15 | Pollution characteristics of particulate matters emitted from outdoor barbecue cooking in urban Jinan in eastern China显示文摘 | Yifei Song Lei Sun Xinfeng Wang Yating Zhang Hui Wang Rui Li Likun Xue Jianmin Chen Wenxing Wang | 2018 | Frontiers of Environmental Science & Engineering2018，12，2： | 0 |
| 16 | Determination of Fosthiazate Residue in Ginger by Gas Chromatography显示文摘[Objectives] An analytical method was established for determining fosthiazate residue in ginger by gas chromatography with flame photometric detector(GC-NPD) to evaluate the safety of fosthiazate in ginger. [Methods] The fosthiazate residue in ginger was extracted with dichloromethane, and subjected to sodium chloride salt-out and liquid-liquid extraction with hexane and dichloromethane(the plant and soil samples had no need for the later two steps). The analysis was performed on gas chromatograph equipped with a flame photometric detector(GC-FPD), and the fosthiazate residue was quantitatively determined by calculating the peak area. [Results] The results of degradation dynamics showed that the half-life of fosthiazate was 7.2-8.7 d in ginger plants, and was 9.9-19.8 d in the soil. The results of the final residue test showed that after applying the fosthiazate granules according to the recommended high dose(active component 58.2 g a.i/m^2,WK) and low dose(38.8 g a.i/m^2,WK) once, the final residual amounts of fosthiazate in the ginger and soil were estimated to be <0.02 mg/kg and <0.02-0.103 mg/kg, respectively, while no fosthiazate residue was detected in all control samples(<0.02 mg/kg). The maximum residue limit(MRL) of fosthiazate in ginger was not established in China, and was 0.2 mg/kg in Japan. [Conclusions] The method was proved to meet the basic requirements of pesticide residue analysis on sensitivity, accuracy and precision and have good linearity. It is recommended that when using fosthiazate granules to control root-knot nematode and root rot in ginger, it is applied at the highest dose of 38.8 g ai/m^2,WK once 30 d before ginger cultivation to treat the soil, and ginger is harvested in the ginger harvest period. | Kailing PENG Yating XIE Chenzhong JIN Xiaoming OU Han XI Xiu LIU Qiangyong SONG Guiping LIANG Zhifu YANG Shunli XIAO Xuye ZHANG | 2019 | Agricultural Biotechnology2019，8，2： | 0 |
| 17 | Low-density polyethylene microplastics partially alleviate the ecotoxicological effects induced by cadmium exposure on the earthworm Eisenia fetida显示文摘LDPE had no effect on the mortality,growth,and reproduction of earthworms.LDPE did not alter the mortality,growth,and reproduction of earth-worm caused by Cd.LDPE alleviated histopathological damage to earthworms caused by Cd.LDPE alleviated DNA damage in earthworm coelomocytes caused by Cd.LDPE did not affect the accumulation of Cd in earthworms.Cadmium(Cd)can accumulate in the food chain,with serious impacts on human health and safety.Microplastics(MPs)such as low-density polyethylene(LDPE)should be considered not only as a single pollutant but also as a carrier of other pollutants.In this study,we investigated the joint effects of 30%LDPE and 313 mg kg-1 Cd on mortality,growth,reproduction,microstructure,DNA damage,oxidative stress,and mRNA levels in the earthworm Eisenia fetida.We found that 313 mg kg-1 Cd inhibited growth and reproduction and damaged the microstructures of the skin and intestine.Meanwhile,LDPE had no effect on the mortality,growth,or cocoon production of earthworms.Moreover,it did not increase the mortality,growth,or inhibition of cocoon production caused by Cd and instead alleviated the DNA damage in coelomocytes caused by Cd treatment.Finally,it did not alter the accumulation of Cd in the worms.These indicators can be used for toxicity safety assessment and soil ecological risk assessment of LDPE and Cd cooccurrence in soil. | Song Zhang Yating Du Guangshen Shang Kejiao Hu Xing Wang | 2024 | Soil Ecology Letters2024，6，1： | 0 |
| 18 | Binary encoding-inspired generation of vector vortex beams显示文摘Vortex and vector terahertz(THz)beams with inhomogeneous polarization states have become a considerable hot topic in the last decade due to their important roles in multiplexed wireless data transmission.However,the technical instruments to form and evaluate such beams are rather limited,as they are mainly collected in the visible range.The emergence of coded metasurfaces has reinvigorated the design of functional devices with multiple degrees of freedom.Here,we demonstrate a versatile design inspired by a binary encoding approach for generating off-axis vectorial THz beams on all-silicon metasurfaces.Experimentally,simultaneous manipulation of the encoding method within the orthogonal circularly polarized(CP)channel provides strong support for developing versatility in vector THz beams,including the generation of arbitrary polarization profiles and the directional emission of multiplexed vector vortex beams(VVBs)with specified polarization states.The introduction of the latitudinal polarization control factor guarantees that continuously rotating or independently designed vector polarization profiles can be obtained on a pre-defined focal plane.Subsequently,a universal parametric theoretical model is developed to analyze the evolutionary trend of off-axis VVB in detail.Notably,the proposed monolayer vector metasurface bypasses the requirement of multiple cascaded optical elements,further inducing the advancement of ultra-thin vector THz sources,and also facilitating the generation of vector fields with tailored polarization distributions in 3D space. | Hui Li Chenglong Zheng Jingyu Liu Hang Xu Chunyu Song Fan Yang Jitao Li Zhen Yue Wei Shi Yating Zhang Yan Zhang Jianquan Yao | 2023 | Science China(Physics,Mechanics & Astronomy)2023，66，5： | 0 |
| 19 | Synergistic effects of plant hormones on spontaneous late-ripening mutant of'Jinghong'peach detected by transcriptome analysis显示文摘Objectives:Peach(Prunus persica L.)is an ancient fruit tree that originated from China.It is the climacteric fruit belonging to genus Prunus in family Rosaceae.Ethylene,which is produced during ripening,accelerates fruit softening,and therefore peaches cannot be stored for a long time.Materials and Methods:To study the mechanism of fruit late ripening,transcriptome analysis of the fruit of a late-ripening mutant of'Jinghong'peach was performed to identify genes and pathways involved in fruit late ripening.Results:A total of 1805,1511,and 2309 genes were found to be differentially expressed in W2_vs_M1,W3_vs_M2,and W3_vs_M3,respectively.Functional enrichment analysis of the differentially expressed genes showed they were related to carotenoid biosynthesis,starch and sucrose metabolism plant hormone signal transduction,flavonoid biosynthesis,and photosynthesis.The expression trends of ripening-related genes that encode transcription factors and plant hormone signal transduction-related genes that encode enzymes were similar.Conclusions:It will help to elucidate the transcriptional regulatory network of fruit development in the spontaneous late-ripening mutant of‘Jinghong’peach and provide a theoretical basis for understanding the molecular regulatory mechanism of fruit ripening. | Man Zhang Tingting Du Yarui Yin Hongyan Cao Zhihua Song Mao Ye Yating Liu Yanhong Shen Libin Zhang Qing Yang Dong Meng Junkai Wu | 2022 | Food Quality and Safety2022，6，1： | 0 |
| 20 | Type I interferon signaling facilitates resolution of acute liver injury by priming macrophage polarization显示文摘Due to their broad functional plasticity,myeloid cells contribute to both liver injury and recovery during acetaminophen overdose-induced acute liver injury(APAP-ALI).A comprehensive understanding of cellular diversity and intercellular crosstalk is essential to elucidate the mechanisms and to develop therapeutic strategies for APAP-ALI treatment.Here,we identified the function of IFN-I in the myeloid compartment during APAP-ALI.Utilizing single-cell RNA sequencing,we characterized the cellular atlas and dynamic progression of liver CD11b+cells post APAP-ALI in WT and STAT2 T403A mice,which was further validated by immunofluorescence staining,bulk RNA-seq,and functional experiments in vitro and in vivo.We identified IFN-I-dependent transcriptional programs in a three-way communication pathway that involved IFN-I synthesis in intermediate restorative macrophages,leading to CSF-1 production in aging neutrophils that ultimately enabled Trem2+restorative macrophage maturation,contributing to efficient liver repair.Overall,we uncovered the heterogeneity of hepatic myeloid cells in APAP-ALI at single-cell resolution and the therapeutic potential of IFN-I in the treatment of APAP-ALI. | Qiaoling Song Shyamasree Datta Xue Liang Xiaohan Xu Paul Pavicic Xiaonan Zhang Yuanyuan Zhao Shan Liu Jun Zhao Yuting Xu Jing Xu Lihong Wu Zhihua Wu Minghui Zhang Zhan Zhao Chunhua Lin Yuxin Wang Peng Han Peng Jiang Yating Qin Wei Li Yingying Zhang Yonglun Luo Ganes Sen George R.Stark Chenyang Zhao Thomas Hamilton Jinbo Yang | 2023 | Cellular & Molecular Immunology2023，20，2： | 0 |
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