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| 1 | Reproductive management through integration of PGD and MPS-based noninvasive prenatal screening/diagnosis for a family with GJB2-associated hearing impairment显示文摘A couple with a proband child of GJB2(encoding the gap junction protein connexin 26)-associated hearing impairment and a previous pregnancy miscarriage sought for a reproductive solution to bear a healthy child. Our study aimed to develop a customized preconception-to-neonate care trajectory to fulfill this clinical demand by integrating preimplantation genetic diagnosis(PGD), noninvasive prenatal testing(NIPT), and noninvasive prenatal diagnosis(NIPD) into the strategy. Auditory and genetic diagnosis of the proband child was carried out to identify the disease causative mutations. The couple then received in-vitro-fertilization treatment, and eight embryos were obtained for day 5 biopsy. PGD was performed by short-tandem-repeat linkage analysis and Sanger sequencing of GJB2 gene. Transfer of a GJB2 c.235del C heterozygous embryo resulted in a singleton pregnancy. At the 13 th week of gestation, genomic DNA(g DNA) from the trio family and cell-free DNA(cf DNA) from maternal plasma were obtained for assessment of fetal chromosomal aneuploidy and GJB2 mutations. NIPT and NIPD showed the absence of chromosomal aneuploidy and GJB2-associated disease in the fetus, which was later confirmed by invasive procedures and postnatal genetic/auditory diagnosis. This strategy successfully prevented the transmission of hearing impairment in the newborn, thus providing a valuable experience in reproductive management of similar cases and potentially other monogenic disorders. | XIONG WenPing WANG DaYong GAO Yuan GAO Ya WANG HongYang GUAN Jing LAN Lan YAN JunHao ZONG Liang YUAN Yuan DONG Wei HUANG SeXin WU KeLiang WANG YaoShen WANG ZhiLi PENG HongMei LU YanPing XIE LinYi ZHAO Cui WANG Li ZHANG QiuJing GAO Yun LI Na YANG Ju YIN ZiFang HAN Bing WANG Wei CHEN Zi-Jiang WANG QiuJu | 2015 | Science China(Life Sciences)2015，58，9： | 12 |
| 2 | TiO_2/Schwertmannite nanocomposites as superior co-catalysts in heterogeneous photo-Fenton process显示文摘The heterogeneous photo-Fenton reaction is an effective technique in combating organic contaminants for both soil and water remediation,and extensive studies have focused on enhancing its efficiency and reducing its costs.In this work,we developed novel photoFenton catalysts by simply milling commercially available TiO_2(P25)with Schwertmannite(Sh),a natural iron-oxyhydroxysulfate nanomineral.We expect that the photo-generated electrons from TiO_2could continuously migrate to Sh,which then could enhance the separation of electron-hole pairs on TiO_2and accelerate the reduction of Fe(III)to Fe(II)on Sh,leading to high degradation efficiency of the target organic contaminants.SEM and TEM results showed the distribution of TiO_2on Sh surface for the nanocomposites(TiO_2/Sh).Under simulated sunlight irradiation,the much higher content of Fe(II)was determined on TiO_2/Sh than on Sh via a common method in the iron ore,and the consumption of H_2O_2and the production of·OH were more significant in the TiO_2/Sh system than those in the TiO_2and Sh systems.These results well support our hypothesis that the photo-generated electrons could migrate from TiO_2to Sh on the composites,and can also explain the much higher degradation efficiency of Rhodamine B(RhB)in the TiO_2/Sh system.Besides,TiO_2/Sh had lower Fe dissolution as compared with Sh,and retained high catalytic stability after four repeated cycles.Above merits of the TiO_2/Sh composites,in combining with their simple synthesis method and low-cost property,indicated that they should have promising applications as heterogeneous photo-Fenton catalysts. | Yanping Zhu Chun Zeng Runliang Zhu Yin Xu Xingyan Wang Huijun Zhou Jianxi Zhu Hongping He | 2019 | Journal of Environmental Sciences2019，31，6： | 5 |
| 3 | Developing controllable hypermutable Clostridium cells through manipulating its methyl-directed mismatch repair system显示文摘Development of controllable hypermutable cells can greatly benefit understanding and harnessing microbial evolution.However,there have not been any similar sys-tems developed for Clostridium,an important bacterial genus.Here we report a novel two-step strategy for de-veloping controllable hypermutable cells of Clostridium acetobutylicum,an important and representative indus-trial strain.Firstly,the mutS/L operon essential for methyl-directed mismatch repair(MMR)activity was inactivated from the genome of C.acetobutylicum to generate hy-permutable cells with over 250-fold increased mutation rates.Secondly,a proofreading control system carrying an inducibly expressed mutS/L operon was constructed.The hypermutable cells and the proofreading control system were integrated to form a controllable hypermut-able system SMBMutC,of which the mutation rates can be regulated by the concentration of anhydrotetracycline(aTc).Duplication of the miniPthl-tetR module of the proof-reading control system further signifi cantly expanded the regulatory space of the mutation rates,demonstrating hypermutable Clostridium cells with controllable mutation rates are generated.The developed C.acetobutylicum strain SMBMutC2 showed higher survival capacities than the control strain facing butanol-stress,indicating greatly increased evolvability and adaptability of the controllable hypermutable cells under environmental challenges. | Guodong Luan Zhen Cai Fuyu Gong Hongjun Dong Zhao Lin Yanping Zhang Yin Li | 2013 | Protein & Cell2013，4，11： | 4 |
| 4 | TWO IMPROVED ALGORITHMS AND IMPLEMENTATION FOR A SINGULARLY PERTURBED PROBLEM ON MOVING MESHES显示文摘这份报纸把一个差别计划用于一个不可思议地使不安的问题。作者由使用能改进数字答案的精确性的理查森推测在动人的网孔方法上提供二个算法。在动人的网孔的传统的算法,起始的网孔是一个一致网孔。作者把它改变到 Bakhvalov-Shishkin 网孔,并且证明它由数字实验改进效率。最后,二个算法的结果被分析。 | Qin ZHOU Yanping CHEN Yin YANG | 2011 | Journal of Systems Science & Complexity2011，24，6： | 4 |
| 5 | Epidemic Characteristics,High-Risk Areas and Space-Time Clusters of Human Brucellosis—China,2020-2021显示文摘Introduction:Analyze the recent epidemiological and temporal-spatial characteristics of human brucellosis in China and provide information for adjusting strategies for brucellosis control.Methods:Human brucellosis data were obtained from the National Notifiable Disease Reporting System(NNDRS).A geographical information system(GIS)was used to visualize high-risk areas with annual incidence based on county(district)polygons.The space-time scan statistic(STSS)was applied to detect the space-time clusters of human brucellosis.Results:A total of 69,767 cases were reported from 2,083 counties in the mainland of China in 2021,a 47.7%increase from 2020(47,425).About 95.5%of the total cases were centralized in northern China and 31.8%in Inner Mongolia(IM).The number of counties with an incidence exceeding 100 per 100,000 was 34 in 2020 and 65 in 2021.From 2020 to 2021,24 space-time clusters were detected.The two primary clusters were located northeast of IM,including 109 counties.The secondary clusters affected 208 counties in 2020 and spread to 297 counties in 2021,the majority of which were located in the middle of IM,exhibiting a trend spreading west from IM to neighboring provincial-level administrative divisions(PLADs).Conclusions:From 2020 to 2021,the incidence of human brucellosis nationwide was exponential,demonstrating distinct spatiotemporal characteristics.Space-time clusters were located in IM and neighboring areas.Therefore,considerable efforts are required to curb this momentum. | Huimin Yang Quilan Chen Yu Li Di Mu Yanping Zhang Wenwu Yin | 2023 | China CDC weekly2023，5，1： | 3 |
| 6 | Effects of exogenous ABA application on post-anthesis dry matter redistribution and grain starch accumulation of winter wheat with different staygreen characteristics显示文摘The objective of this study was to investigate whether and how exogenous abscisic acid(ABA)is involved in mediating starch accumulation in the grain and redistribution of carbohydrates during grain filling of two wheat cultivars with different staygreen characteristics.At blooming stage,plants of Wennong 6(a staygreen cultivar)and Jimai 20(control)were sprayed with10 mg L-1abscisic acid(ABA)for 3 days.The application of ABA significantly(P<0.05)increased grain filling rate,starch accumulation rate and content,remobilization of dry matters to kernels,and 1000-grain weight of the two cultivars.Exogenous ABA markedly(P<0.05)increased grain yield at maturity,and Wennong 6 and Jiami 20 showed 14.14%and 4.86%higher compared yield than the control.Dry matter accumulation after anthesis of Wennong 6 was also significantly(P<0.05)influenced by exogenous ABA,whereas that of Jimai 20 was unchanged.Application of ABA increased endogenous zeatin riboside(ZR)content 7 days after anthesis(DAA),and spraying ABA significantly increased endogenous indole-3-acetic acid(IAA)and ABA contents from 7 to 21 DAA and decreased gibberellin(GA3)content at 14 DAA,but increased GA3content from 21 to 35 DAA.The results suggested that increased yield of staygreen was due to greater starch assimilation owing to a higher filling rate and longer grain-filling duration. | Dongqing Yang Yongli Luo Yingli Ni Yanping Yin Weibing Yang Dianliang Peng Zhengyong Cui Zhenlin Wang | 2014 | The Crop Journal2014，2，Z1： | 3 |
| 7 | Filtration characteristics of granular bed with layered drawers for removing dust from gas streams显示文摘Filtration tests were conducted on a granular bed filter with layered drawers filled with corundum particles with sizes between either 1 mm and 1.5 mm or 2 mm and 3 mm or with quartz sand particles with sizes between 0.125 mm and 1.5 mm.Filtration velocity,filter particle thickness,and filter particle size were all found to influence the filtration efficiency and the pressure drop of both the fixed granular bed and the layered-drawer granular bed.Granular strata with different thickness ratios also strongly influenced the filtration efficiency and pressure drop.For a granular bed with two sizes of filter particles,the coarse granules in the upper layer capture dust with large particle sizes,while the fine granules in the lower layer capture dust with smaller particle sizes that passes through the filter cake and upper layer.Optimal operating conditions were determined at which the filtration efficiency was found to be 99.42%with a bed pressure drop of 320 Pa. | Shaowu Yin Xu Wang Yanping Guo Li Wang | 2021 | Particuology2021，19，2： | 3 |
| 8 | Experimental and theoretical studies of the reaction between cationic vanadium oxide clusters and acetylene显示文摘The time of flight mass spectrometer coupled with a laser ablation/supersonic expansion cluster source and a fast flow reactor was adopted to study the reactivity of cationic vanadium oxide clusters(VmOn+) toward acetylene(C2H2) molecules under gas phase(P,~ 1.14 kPa),under near room temperature(T,~ 350 K) conditions.Association products,VmOnC2H2+(m,n = 2,4;2,6;3,7―8;4,9―11;5,12―13;6,13―16,and 7,17),are observed.The oxidation of C2H2 by(V2O5)+n(n = 1―3) is experimentally identified.The reactivity of(V2O5)+ n decreases as n increases.Density functional theory(DFT) calculations were carried out to interpret the reaction mechanisms.The DFT results indicate that a terminal oxygen atom from V2O5+ can transfer overall barrierlessly to C2H2 at room temperature,which is in agreement with the experimental observation.Other experimental results such as the observation of V2O6C2H+2 and non-observation of V2O7,8C2H+2 in the experiments are also well interpreted based on the DFT calculations.The reactivity of vanadium oxide clusters toward acetylene and other hydrocarbons may be considered in identifying molecular level mechanisms for related heterogeneous catalysis. | YIN Shi MA YanPing DU Lin HE ShengGui GE MaoFa | 2008 | Chinese Science Bulletin2008，53，24： | 3 |
| 9 | Finite Control Set Model Predictive Torque Control Using Sliding Model Control for Induction Motors显示文摘Finite control set model predictive torque control(FCS-MPTC)has become increasingly prevalent for induction motors(IM)owing to its simple concept,easy incorporation of constraints and strong flexibility.In traditional FCS-MPTC speed controller design,a classical proportional integral(PI)controller is typically chosen to generate the torque reference.However,the PI controller is dependent on system parameters and sensitive to the load torque variation,which seriously affects control performance.In this paper,a model predictive torque control using sliding mode control(MPTC+SMC)for IM is proposed to enhance the robust performance of the drive system.First,the influence of the parameter mismatches for FCS-MPTC is analyzed.Second,the shortcomings of traditional PI controller are derived.Then,the proposed MPTC+SMC method is designed,and the MPTC+PI and MPTC+SMC are compared theoretically.Finally,experimental results demonstrate the correctness and effectiveness of the proposed MPTC+SMC.In comparison with MPTC+PI,MPTC+SMC has the better dynamic performance and stronger robust performance against parameter variations and load disturbance. | Yanqing Zhang Zhonggang Yin Wei Li Jing Liu Yanping Xu | 2021 | CES Transactions on Electrical Machines and Systems2021，5，3： | 2 |
| 10 | Variation of high-molecular-weight glutenin subunits and glutenin macropolymer particle distribution in wheat grains produced under different water regimes显示文摘The components and contents of high-molecular-weight glutenin subunits(HMW-GS) in wheat grains affect glutenin macropolymer(GMP) size, which is considered an important flour quality trait in wheat. Four wheat cultivars(Shiluan 02-1, Yannong 24, Jinan 17 and Lumai 21) with different end-use qualities were used to investigate the HMW-GS and GMP contents, and the GMP particle distributions in grain produced under irrigated and rainfed conditions. The percent volume of GMP particles and the contents of HMW-GS and GMP were affected by genotype and soil water. Genotype × soil water interaction was significant only for GMP particles <12 μm and >100 μm in the growing season of 2010–2011. Irrigated and rainfed conditions had different influences on the GMP particle distribution in the four cultivars. Compared to irrigated treatment, the rainfed treatment had higher accumulations of HMW-GS and GMP, especially in cultivars Yannong 24, Jinan 17 and Lumai 21. Rainfed conditions also increased the proportion of large size particles of GMP, indicating that different water regimes had an effect on grain quality. According to correlation coefficients(r), the contents of HMW-GS and GMP in grains were negatively correlated with the volume of <12 μm GMP particles, but positively correlated with GMP particles >100 μm. | Zhongmin Dai Yanping Yin Yong Li Li Cao Zhenlin Wang | 2013 | The Crop Journal2013，1，1： | 2 |
| 11 | Changes of Glutenin Subunits due to Water-Nitrogen Interaction Influence Size and Distribution of Glutenin Macropolymer Particles and Flour Quality显示文摘 | Li Yong Yin Yanping Zhao Qi Wang Zhenlin | 2011 | Crop Science2011，，6： | 1 |
| 12 | Radiofrequency Ablation Versus Antiarrhythmic Medication for Treatment of Ventricular Premature Beats From the Right Ventricular Outflow Tract: Prospective Randomized Study显示文摘 | Zhiyu Ling Zengzhang Liu Li Su Vadim Zipunnikov Jinjin Wu Huaan Du Kamsang Woo Shaojie Chen Bin Zhong Xianbin Lan Jinqi Fan Yanping Xu Weijie Chen Yuehui Yin Saman Nazarian Bernhard Zrenner | 2014 | Circulation: Arrhythmia and Electrophysiology2014，，2： | 1 |
| 13 | Ca^(2+)-dependent TaCCD1 cooperates with TaSAUR215 to enhance plasma membrane H^(+)-ATPase activity and alkali stress tolerance by inhibiting PP2C-mediated dephosphorylation of TaHA2 in wheat显示文摘Alkali stress is a major constraint for crop production in many regions of saline-alkali land.However,little is known about the mechanisms through which wheat responds to alkali stress.In this study,we identified a calcium ion-binding protein from wheat,TaCCD1,which is critical for regulating the plasma membrane(PM)H^(+)-ATPase-mediated alkali stress response.PM H+-ATPase activity is closely related to alkali tolerance in the wheat variety Shanrong 4(SR4).We found that two D-clade type 2C protein phosphatases,TaPP2C.D1 and TaPP2C.D8(TaPP2C.D1/8),negatively modulate alkali stress tolerance by dephosphorylating the penultimate threonine residue(Thr926)of TaHA2 and thereby inhibiting PM H+-ATPase activity.Alkali stress induces the expression of TaCCD1 in SR4,and TaCCD1 interacts with TaSAUR215,an early auxin-responsive protein.These responses are both dependent on calcium signaling triggered by alkali stress.TaCCD1 enhances the inhibitory effect of TaSAUR215 on TaPP2C.D1/8 activity,thereby promoting the activity of the PM H^(+)-ATPase TaHA2 and alkali stress tolerance in wheat.Functional and genetic analyses verified the effects of these genes in response to alkali stress,indicating that TaPP2C.D1/8 function downstream of TaSAUR215 and TaCCD1.Collectively,this study uncovers a new signaling pathway that regulates wheat responses to alkali stress,in which Ca^(2+)-dependent TaCCD1 cooperates with TaSAUR215 to enhance PM H+-ATPase activity and alkali stress tolerance by inhibiting TaPP2C.D1/8-mediated dephosphorylation of PM H+-ATPase TaHA2 in wheat. | Minghan Cui Yanping Li Jianhang Li Fengxiang Yin Xiangyu Chen Lumin Qin Lin Wei Guangmin Xia Shuwei Liu | 2023 | Molecular Plant2023，16，3： | 1 |
| 14 | Synthesis of Heterometallic Rare Earth(Ⅲ)-Cobalt(Ⅱ)Complexes and Their Application in Alternating Copolymerization of Cyclohexene Oxide and Carbon Dioxide显示文摘Comprehensive Summary Four heterometallic rare earth(Ⅲ)-cobalt(Ⅱ)complexes(rare earth=Y(1),Sm(2),Nd(3),La(4))stabilized by an o-phenylenediamine-bridged tris(phenolato)ligand(L)have been synthesized and characterized.In these tetranuclear complexes,one polydentate L coordinates to one rare earth(Ⅲ)ion,and one cobalt(Ⅱ)ion,respectively,while two rare earth ions are bridged by four acetate groups.These complexes were applied in the copolymerization of cyclohexene oxide and CO_(2),which showed good activity(TON up to 440)and high poly(cyclohexene carbonate)selectivity(>99%).Kinetic studies determined the equation as rate=k[CHO]1[CO_(2)]0[initiator]1,which proves a first-order dependence on initiator concentrations and implies a synergistic mechanism with rare earth and cobalt ions cooperating in epoxide ring-opening and chain propagation. | Yanping Song Kuan Yin Yongjie Chen Bei Zhao Yong Zhang Xuehua Zhu Dan Yuan Yingming Yao | 2023 | Chinese Journal of Chemistry2023，41，7： | 1 |
| 15 | Engineering stress tolerance of Escherichia coli by stress‐induced mutagenesis (SIM)‐based adaptive evolution显示文摘 | Linjiang Zhu Zhen Cai Yanping Zhang Yin Li | 2014 | Biotechnology Journal2014，，1： | 1 |
| 16 | Finite difference approximation for a class of nonlocal parabolic equations 显示文摘 | LIN Yanping XU Shuzhan YIN Hongming | 1997 | IntJ Math MathSci1997，20，： | 1 |
| 17 | Awareness Towards Rabies and Exposure Rate and Treatment of Dog-Bite Injuries Among Rural Residents—Guangxi Zhuang Autonomous Region,China,2021显示文摘Summary What is already known about this topic?Although fatal once clinical signs appear,rabies is preventable through three proven,effective interventions including mass dog vaccination,postexposure prophylaxis(PEP),and,though sometimes neglected,awareness of rabies.What is added by this report?The total awareness rate of rabies-related knowledge among rural residents was only 57.9%in Guangxi Zhuang Autonomous Region,one of the provinciallevel administrative divisions(PLADs)with endemic rabies in China. | Mantong Zhu Di Mu Qiulan Chen Ning Chen Yanping Zhang Wenwu Yin Yu Li Yingjie Chen Yidan Deng Xianyan Tang | 2021 | China CDC weekly2021，3，53： | 1 |
| 18 | The characteristics of combustion in a centrifugal-thermite process显示文摘 | LIU MU SHENG YIN WEI YANPING LAI HEYI | 1997 | Journal of Materials Science1997，，17： | 1 |
| 19 | Assessing Impacting Factors of Dog Owners’Adoption of Dog Vaccination Against Rabies:A Cross-sectional Survey in Rural Areas—Guangxi Zhuang Autonomous Region,China,2021显示文摘Summary What is already known about this topic?Rabies is fatal while preventable.More than 99%of human rabies cases were caused by dog bites worldwide.Mass dog vaccination could interrupt dogmediated rabies if achieving and maintaining a minimum coverage rate of 70%.What does this report contribute?The results of this study show that roughly 23.7%of households owned dogs in Guangxi Zhuang Autonomous Region. | Ning Chen Qiulan Chen Yanping Zhang Mantong Zhu Wenwu Yin Di Mu Yu Li Yingjie Chen Yidan Deng Xianyan Tang | 2021 | China CDC weekly2021，3，42： | 0 |
| 20 | Investigation Report on the Present Situation of Subjective Well-being of Aged People in the Xianning City显示文摘 | Yanping Hong Qili Yin Biyun Zhang | 2016 | International Journal of Technology Management2016，，12： | 0 |
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