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| 1 | Association between TNF-a and IL-1β genotypes vs Helicobacter pylori infection in Indonesia显示文摘AIM:To investigate the correlation between the Helicobacter pylori(H.pylori)infection and host genetic background of healthy populations in Indonesia.METHODS:In March 2007,epidemiological studies were undertaken on the general population of a city in Indonesia(Mataram,Lombok).The participants included 107 men and 187 women,whose ages ranged from6 to 74 years old,with an average age of 34.0(±14.4)(±SD).The H.pylori of subject by UBT method determination,and through the polymerase chain reaction with confronting two-pair primers(PCR-CTPP)method parsing the single nucleotide polymorphism of interleukin(IL)-8,IL-4,IL-1β,CD14,tumor necrosis factor(TNF-a)and tyrosine-protein phosphates non-receptor type 11(PTPN11)genotypes.The experimental data were analyzed by the statistical software SAS.RESULTS:The H.pylori infection rates in the healthy Indonesian population studied were 8.4%for men and12.8%for women;no obvious differences were noted for H.pylori infection rates by sex or age.TC genotypes of IL-4,TC and CC genotypes of TNF-a,and GA genotypes of PTPN11,were higher in frequency.Both CC and TC genotype of TNF-a T-1031C loci featured higher expressions in the healthy Indonesian population Indonesia studied of(OR=1.99;95%CI:0.67-5.89)and(OR=1.66;95%CI:0.73-3.76),respectively.C allele of IL-1βT-31C gene locus was at a higher risk(OR=1.11;95%CI:0.70-1.73)of H.pylori infection,but no statistical significance was found in our study.CONCLUSION:We reveal that the association between the TNF-a and IL-1βgenotypes may be the susceptibility of H.pylori in the studied population. | Yang Zhao Jing-Wen Wang Tsutomu Tanaka Akihiro Hosono Ryosuke Ando Shinkan Tokudome Soeripto FX Ediati Triningsih Tegu Triono Suwignyo Sumoharjo EY Wenny Astuti Achwan Stephanus Gunawan Yu-Min Li | 2013 | World Journal of Gastroenterology2013，19，46： | 5 |
| 2 | Matrix metalloproteinase- mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat显示文摘 | Yang Y Estrada EY Thompson JF | 2007 | J Cereb Blood Flow Metab2007，27，： | 1 |
| 3 | The clinical value of CA125 and adenosine deaminase(ADA) in tuberculous peritonitis patient显示文摘 | SHAN GD JIN EY YANG M | 2006 | Chin J Intern Med2006，45，11： | 1 |
| 4 | Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat显示文摘 | Yang Y Estrada EY Thompson JF | 2007 | J Cereb Blood Flow Metab2007，27，： | 1 |
| 5 | Neural stem cells spontaneously express dopaminergic traits after transplantation into the intact or 6-hydroxydopamine-lesioned rat 显示文摘 | Yang M Snyder EY Iacovitti L | 2002 | Exp Neuro12002，177，1： | 1 |
| 6 | Matrix metalloproteinase- mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal is- chemia in rat显示文摘 | Yang Y Estrada EY Thompson JF | 2007 | J Cereb Blood Flow Metab2007，4，： | 1 |
| 7 | Fluoride induces vascular contraction through activation of RhoA/Rho kinase pathway in isolated rat aortas显示文摘 | Yang EY Jeon SB Baek I | 2010 | Environ Toxicol Pharmaeol2010，29，3： | 1 |
| 8 | The impact of economic crisis on health-care consumption in Korea 显示文摘 | YANG BM PRESCOTT N BAE EY | 2001 | Health Policy Plan2001，，16： | 1 |
| 9 | Down regulation of cir- cadian clock gene Period 2 accelerates breast cancer growth by altering its daily growth rhythm显示文摘 | Yang X Wood PA Oh EY | 2009 | Breast Cancer Res Treat2009，117，2： | 1 |
| 10 | Fetoscopy显示文摘 | Yang EY Adzick NS | 1998 | Semin Laparosc Surg1998，5，1： | 1 |
| 11 | Predictors of survival after acute paraquat poisoning显示文摘 | Lee EY Hwang KY Yang JO | 2002 | Toxicol Ind Health2002，18，4： | 1 |
| 12 | Cyst formation in kidney via B- Raf signaling in the PKD2 transgenic mice显示文摘 | Park EY Sung YH Yang MH | 2009 | J Biol Chem2009，284，11： | 1 |
| 13 | Matrix Metalloproteinase-mediated Disruption of Tight Junction Proteins in Cerebral Vessels Is Reversed by Synthetic Matrix Metalloproteinase Inhibitor in Focal Isehemia in Rat显示文摘 | Yang Y Estrada EY Thompson JF | 2008 | J Cereb Blood Flow Metab(S0271- 678X)2008，27，4： | 1 |
| 14 | Pred ictors of surv ival after acuteparaquat poisoning显示文摘 | Lee EY Hwang KY Yang JO | | 0，，04： | 1 |
| 15 | Human and rat mesangial cell receptors for glucose - modified proteins: potential role in kidney tissue remodelling and diabetic nephropathy 显示文摘 | Skolnik EY Yang Z Makita Z | 1991 | J Exp Med1991，174，4： | 1 |
| 16 | Clinical implication of urinary neutrophil gelatinase-associated lipocalin and kidney injury mole- cule-1 in patients with acute paraquat intoxication 显示文摘 | Gil HW Yang JO Lee EY | 2009 | Clin Toxico12009，47，9： | 1 |
| 17 | Auditory brainstem response thresholds to air and bone conducted clicks in neonates and adults显示文摘 | Stuart A Yang EY Stenstrom R | 1993 | Am J Otol1993，14，： | 1 |
| 18 | Auditory brain stem responses to air-and bone-conducted clicks in the audiological assessment of at-risk infants显示文摘 | Yang EY Stuart A Mencher GT | 1993 | Ear Hear1993，14，： | 1 |
| 19 | Matrix metalloproteinase-mediated disruption of tight junction proteins in cerebral vessels is reversed by synthetic matrix metalloproteinase inhibitor in focal ischemia in rat显示文摘 | Yang Y Estrada EY Thompson JF | | 0，，04： | 1 |
| 20 | Predictors of survival afteracute paraquat poisoning显示文摘 | Lee EY Hwang KY Yang JO | 2002 | Toxicol Ind Health2002，18，4： | 1 |
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