维普中文期刊产品整合服务
99篇 您的检索式:作者名="Yaffe B"
    题名 作者 年代 出处 被引量
1美国国立老化研究所与阿尔茨海默病协会诊断指南写作组:阿尔茨海默病临床前阶段的定义显示文摘阿尔茨海默病(AD)的病理生理过程在痴呆诊断的多年前就开始了。这一长期的AD“临床前”阶段是治疗干预的关键机会,但需进一步阐明AD的病理级联过程和临床症状出现之间的联系。美国国立老化研究所和AD协会召集了一个国际工作组对AD生物标志物、流行病学和神经心理学的证据进行综述并提出建议,以确定能够预测由“正常”认知到轻度认知功能障碍(MCI)及AD痴呆的最佳预测指标。根据目前已有的主要科学证据,我们提出了一个概念性的框架和用于操作的研究标准,以通过纵向临床研究来验证和改进这些模型。这些建议仅用于研究目的,目前不涉及临床应用。我们希望这些建议能提供一个共识,以推进临床前AD的研究,最终推动更早期治疗干预的进展,使得一些疾病减缓药物的疗效发挥最大。Sperling RA Aisen PS Beckett LA Bennett DA Craft S Fagan AM Iwatsubo T Jack CR Jr Kaye J Montine TJ Park DC Reiman EM Rowe CC Siemers E Stern Y Yaffe K Carrillo MC Thies B Morrison-Bogorad M Wagster MV Phelps CH 贾建平(译) 郭起浩(译) 黄丽(译) 陆璐(译) 张逸驰(译) 邢怡(译) 2012中华神经科杂志2012,45,5:22
2Affinity-driven peptide selection of an NFAT inhibitor more selective than cyclosporin A显示文摘Aramburu J Yaffe M B Lopez-Rodriguez C 1999Science1999,285,5436:1
3The structural ba- sis for 14-3-3 : phosphopeptide binding specificity 显示文摘Yaffe M B Rittinger K Volinia S 1997Cell1997,91,7:1
4Effective kinetic theory for high temperature gauge theories显示文摘Arnold P B Moore G D Yaffe L G 2003Journal of High Energy Physics2003,1,01:1
5TAZ:a Beta-catenin-like Molecule that Regulates Mesenchymal Stem Cell Differentiation 显示文摘Hong J H Yaffe M B 2006Cell Cycle2006,5,:1
6MAP kinase pathways activated by stress: the p38 MAPK pathway显示文摘Obata T Brown G E Yaffe M B 2000Crit Cace Med2000,28,4:1
7How do 14-3-3 proteins work?--Gatekeeper phosphorylation and the molecular anvil hypothesis显示文摘Yaffe M B 2002Febs Lett2002,513,:1
8How do 14-3-3 proteins work? -Gatekeeper phosphorylation and the molecular anvil hypothe-sis显示文摘Yaffe M B 2002FEBS Letters2002,513,1:1
9Computational ap- proaches for analyzing information flow in biological net- works 显示文摘Kholodenko B Yaffe MB Kolch W 2012Sci Signal2012,5,220:1
10Structure and function of Polo-like kinases 显示文摘Lowery D M Lin D Yaffe M B 2005Oncogene2005,24,2:1
11Structural de-terminants of 14-3-3 binding specificities and regulation of subcellular localization of 14-3-3-ligand complexes: a comparison of the X-ray crystal structures of all human 14-3-3 isoforms 显示文摘Gardino A K Smerdon S J Yaffe M B 2006Seminars in Cancer Biology2006,16,3:1
12Successful replantation of a totally avulsed scalp 显示文摘Yaffe B Shvoron A 1986J Reeonstr Microsurg1986,2,3:1
1314-3-3 proteins-a focus on cancer and human disease显示文摘Wilker E Yaffe M B 2004J Mol Cell Cardiol2004,37,3:1
14MAP kinase pathways activated by stress:the p38MAPK pathway显示文摘Toshiyuki Obata Brown G E Yaffe M B 2000Crit Care Med2000,28,4:1
15MAP kinase pathways acti- vated by stress: the p38 MAPK pathway显示文摘Obata T Brown G E Yaffe M B 2000Crit Care Med2000,28,4:1
16How do 14-3-3 proteins work-gatekeeperphos-phorylation and the molecular anvil hypothesis显示文摘Yaffe M B 2002FEBS Lett2002,513,1:1
17How do 14-3-3 proteins work? Gatekeeper phosphorylation and the molecular anvil hypothesis显示文摘Yaffe M B 2002FEBS Lett2002,513,1:1
18How do 14-3-3 proteins work? Gatekeeper phosphorylation and the molecular anvil hypothesis显示文摘YAFFE M B 2002FEBS Lett2002,513,1:1
19MAP kinase pathways activated by stress: the p38 MAPK pathway 显示文摘Obata T Brown G E Yaffe M B 2000Crit Care Med2000,28,4:1
2014-3-3 prot eins:a focus on cancer and human disease 显示文摘Wilker E Yaffe M B 2004J Mol Cell Cardiol2004,37,3:1
返回顶部 每页显示:
共5页 首页 上一页 第1页 下一页 末页 /5 跳转

网站首页 | 关于我们 | 联系我们 | 产品服务 | 客服中心 | 广告服务 | 版权声明 | 网站联盟 | 友情链接 | 售卡网点

版权所有© 渝B2-20050021-1 渝公网安备 50019002500403号 违法和不良信息举报中心

互联网出版许可证 新出网证(渝)字10号 全国400电话 - 免长途话费