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17篇 您的检索式:作者名="YU Haochen"
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1A Model Output Machine Learning Method for Grid Temperature Forecasts in the Beijing Area显示文摘In this paper, the model output machine learning (MOML) method is proposed for simulating weather consultation, which can improve the forecast results of numerical weather prediction (NWP). During weather consultation, the forecasters obtain the final results by combining the observations with the NWP results and giving opinions based on their experience. It is obvious that using a suitable post-processing algorithm for simulating weather consultation is an interesting and important topic. MOML is a post-processing method based on machine learning, which matches NWP forecasts against observations through a regression function. By adopting different feature engineering of datasets and training periods, the observational and model data can be processed into the corresponding training set and test set. The MOML regression function uses an existing machine learning algorithm with the processed dataset to revise the output of NWP models combined with the observations, so as to improve the results of weather forecasts. To test the new approach for grid temperature forecasts, the 2-m surface air temperature in the Beijing area from the ECMWF model is used. MOML with different feature engineering is compared against the ECMWF model and modified model output statistics (MOS) method. MOML shows a better numerical performance than the ECMWF model and MOS, especially for winter. The results of MOML with a linear algorithm, running training period, and dataset using spatial interpolation ideas, are better than others when the forecast time is within a few days. The results of MOML with the Random Forest algorithm, year-round training period, and dataset containing surrounding gridpoint information, are better when the forecast time is longer.Haochen LI Chen YU Jiangjiang XIA Yingchun WANG Jiang ZHU Pingwen ZHANG 2019Advances in Atmospheric Sciences2019,36,10:9
2Machine Learning−based Weather Support for the 2022 Winter Olympics显示文摘1.A key support for the 2022 Winter Olympics The XXIV Olympic Winter Games are scheduled to take place from 4 to 22 February 2022,followed by the Paralympic Games from 4 to 13 March,in Beijing and towns in the neighboring Hebei Province,China.Weather plays an extremely important role in the outcome of the games(Chen et al.,2018).It can not only cause a difference between a medal or not,but affect the safety of athletes.Success of the Winter Olympics will greatly depend on weather conditions at the outdoor competition venues,dealing with many weather elements including the snow surface temperature,apparent temperature,gust wind speed,snow,visibility,etc.To ensure that the scheduled games go smoothly,it is imperative to have hourly or even every 10-minutely forecasts as well as updated weather-related risk assessments at the venues for the next 240 hours.So far,the Beijing/Hebei Meteorological Observatory has already started intelligent weather forecasting at 3-km resolution based on the results of numerical weather prediction(NWP)models.However,these experiments have suggested that the current forecasting techniques are incapable of capturing the complex mountain weather variations around some venues.The forecasting capability of NWP is constrained partly by limited knowledge of the local weather mechanisms.Jiangjiang XIA Haochen LI Yanyan KANG Chen YU Lei JI Lve WU Xiao LOU Guangxiang ZHU Zaiwen Wang Zhongwei YAN Lizhi WANG Jiang ZHU Pingwen ZHANG Min CHEN Yingxin ZHANG Lihao GAO Jiarui HAN 2020Advances in Atmospheric Sciences2020,37,9:6
3Novel MSX1 variants identified in families with nonsyndromic oligodontia显示文摘The goal of this study was to identify MSX1 gene variants in multiple Chinese families with nonsyndromic oligodontia and analyse the functional influence of these variants.Whole-exome sequencing(WES)and Sanger sequencing were performed to identify the causal gene variants in five families with nonsyndromic oligodontia,and a series of bioinformatics databases were used for variant confirmation and functional prediction.Phenotypic characterization of the members of these families was described,and an in vitro analysis was performed for functional evaluation.Five novel MSX1 heterozygous variants were identified:three missense variants[c.662A>C(p.Q221P),c.670C>T(p.R224C),and c.809C>T(p.S270L)],one nonsense variant[c.364G>T(p.G122*)],and one frameshift variant[c.277delG(p.A93Rfs*67)].Preliminary in vitro studies demonstrated that the subcellular localization of MSX1 was abnormal with the p.Q221P,p.R224C,p.G122*,and p.A93Rfs*67 variants compared to the wild type.Three variants(p.Q221P,p.G122*,and p.A93Rfs*67)were classified as pathogenic or likely pathogenic,while p.S270L and p.R224C were of uncertain significance in the current data.Moreover,we summarized and analysed the MSX1-related tooth agenesis positions and found that the type and variant locus were not related to the severity of tooth loss.Our results expand the variant spectrum of nonsyndromic oligodontia and provide valuable information for genetic counselling.Jinglei Zheng Miao Yu Haochen Liu Tao Cai Hailan Feng Yang Liu Dong Han 2021International Journal of Oral Science2021,13,1:4
4A 10×10 deep ultraviolet light-emitting micro-LED array显示文摘In this work,we design and fabricate a deep ultraviolet(DUV)light-emitting array consisting of 10×10 micro-LEDs(μ-LEDs)with each device having 20μm in diameter.Strikingly,the array demonstrates a significant enhancement of total light output power by nearly 52%at the injection current of 100 mA,in comparison to a conventional large LED chip whose emitting area is the same as the array.A much higher(~22%)peak external quantum efficiency,as well as a smaller efficiency droop forμ-LED array,was also achieved.The numerical calculation reveals that the performance boost can be attributed to the higher light extraction efficiency at the edge of eachμ-LED.Additionally,the far-field pattern measurement shows that theμ-LED array possesses a better forward directionality of emission.These findings shed light on the enhancement of the DUV LEDs performance and provide new insights in controlling the light behavior of theμ-LEDs.Huabin Yu Muhammad Hunain Memon Hongfeng Jia Haochen Zhang Meng Tian Shi Fang Danhao Wang Yang Kang Shudan Xiao Shibing Long Haiding Sun 2022Journal of Semiconductors2022,43,6:3
5N-doped-carbon coated Ni2P-Ni sheets anchored on graphene with superior energy storage behavior显示文摘Transition metal phosphides (TMPs) have been widely studied as electrode materials for supercapacitors and lithium-ion batteries due to their high electrochemical reacti on activities. The practical applicati on of TMPs was gen erally hampered by their low con ductivity and large volume changes during electrochemical reactions. In this work, nitrogen-doped-carbon (NC) coated Ni2P-Ni hybrid sheets were fabricated and loaded into highly con ductive graphe ne n etwork, forming a Ni2P ?Ni@NC@G composite. The highly con ductive g raphe ne, the NC coati ng layer, and the decorated Ni nano particles in combi nation offer continu ous electro n tran sport cha nnels in the composite, resulti ng with facilitated electrode reaction kinetics and superior rate performance. Besides, the flexible graphene sheets and well-decorated Ni particles among Ni2P can effectively buffer the harmful stress during electrochemical reactions to maintain an integrated electrode structure. With these favorable features, the composite dem on strated superior capacitive and lithium storage behavior. As an electrode material for supercapacitors, the composite shows a remarkable capacitance of 2,335.5 F·g^-1 at 1 A·g^-1 and high capacitance retention of 86.4% after 2,000 cycles. Asymmetrical supercapacitors (ASCs) were also prepared with remarkable energy density of 53.125 Whk·g^-1 and power density of 3,750 Whk·g^-1. As an anode for lithium ion batteries, a high reversible capacity of 1,410 mAh·g^-1 can be delivered at 0.2 A·g^-1 after 200 cycles. Promising high rate capability was also demonstrated with a high discharge capacity of 750 mAh·g^-1 at 8 A·g^-1. This work shall pave the way for the production of other TMP materials for energy storage systems.Yuanxing Zhang Li Sun Liqi Bai Haochen Si Yu Zhang Yihe Zhang 2019Nano Research2019,12,3:3
6Hippo-YAP/TAZ signaling in osteogenesis and macrophage polarization:Therapeutic implications in bone defect repair显示文摘Bone defects caused by diseases or surgery are a common clinical problem.Researchers are devoted to finding biological mechanisms that accelerate bone defect repair,which is a complex and continuous process controlled by many factors.As members of transcriptional costimulatory molecules,Yes-associated protein(YAP)and transcriptional co-activator with PDZ-binding motif(TAZ)play an important regulatory role in osteogenesis,and they affect cell function by regulating the expression of osteogenic genes in osteogenesis-related cells.Macrophages are an important group of cells whose function is regulated by YAP/TAZ.Currently,the relationship between YAP/TAZ and macrophage polarization has attracted increasing attention.In bone tissue,YAP/TAZ can realize diverse osteogenic regulation by mediating macrophage polarization.Macrophages polarize into M1 and M2 phenotypes under different stimuli.M1 macrophages dominate the inflammatory response by releasing a number of inflammatory mediators in the early phase of bone defect repair,while massive aggregation of M2 macrophages is beneficial for inflammation resolution and tissue repair,as they secrete many anti-inflammatory and osteogenesis-related cytokines.The mechanism of YAP/TAZ-mediated macrophage polarization during osteogenesis warrants further study and it is likely to be a promising strategy for bone defect repair.In this article,we review the effect of Hippo-YAP/TAZ signaling and macrophage polarization on bone defect repair,and highlight the regulation of macrophage polarization by YAP/TAZ.Haochen Wang Hui Yu Tianyu Huang Bin Wang Lin Xiang 2023Genes & Diseases2023,10,6:2
7Optimization Scheme of Large Passenger Flow in Huoying Station,Line 13 of Beijing Subway System显示文摘This paper focuses on the distribution of passenger flow in Huoying Station,Line 13 of Beijing subway system.The transformation measures taken by Line 13 since operation are firstly summarized.Then the authors elaborate the facilities and equipment of this station,especially the node layout and passenger flow field.An optimization scheme is proposed to rapidly distribute the passenger flow in Huoying Station by adjusting the operation time of the escalator in the direction of Xizhimen.The authors adopt Queuing theory and Anylogic simulation software to simulate the original and the optimized schemes of Huoying Station to distribute the passenger flow.The results of the simulation indicate that the optimized scheme could effectively alleviate the traffic congestion in the hall of Huoying Station,and the pedestrian density in other places of the hall is lowered;passengers could move freely in the hall and no new congestion points would form.The rationality of the scheme is thus proved.Jin Zhou Haochen Wang Di Sun Siqiang Xu Meng Lv Feifei Yu 2020Computers, Materials & Continua2020,,6:2
8A Comprehensive Evaluation Framework of Water-Energy-Food System Coupling Coordination in the Yellow River Basin,China显示文摘For mankind’s survival and development,water,energy,and food(WEF)are essential material guarantees.In China,however,the spatial distribution of WEF is seriously unbalanced and mismatched.Here,a collaborative governance mechanism that aims at nexus security needs to be urgently established.In this paper,the Yellow River Basin in China with a representative WEF system,was selected as a case.Firstly,a comprehensive framework for WEF coupling coordination was constructed,and the relationship and mechanism between them were analyzed theoretically.Then,we investigated the spatiotemporal characteristics and driving mechanisms of the coupling coordination degree(CCD)with a composite evaluation method,coupling coordination degree model,spatial statistical analysis,and multiscale geographic weighted regression.Finally,policy implications were discussed to promote the coordinated development of the WEF system.The results showed that:1)WEF subsystems showed a significant imbalance of spatial pattern and diversity in temporal changes;2)the CCD for the WEF system varied little and remained at moderate coordination.Areas with moderate coordination have increased,while areas with superior coordination and mild disorder have decreased.In addition,the spatial clustering phenomenon of the CCD was significant and showed obvious characteristics of polarization;and 3)the action of each factor is self-differentiated and regionally variable.For different factors,GDP per capita was of particular importance,which contributed most to the regional development’s coupling coordination.For different regions,GDP per capita,average yearly precipitation,population density,and urbanization rate exhibited differences in geographical gradients in an east-west direction.The conclusion can provide references for regional resource allocation and sustainable development by enhancing WEF system utilization efficiency.YIN Dengyu YU Haochen LU Yanqi ZHANG Jian LI Gensheng LI Xiaoshun 2023Chinese Geographical Science2023,33,2:1
9A Deep Spatio-Temporal Forecasting Model for Multi-Site Weather Prediction Post-Processing显示文摘In this paper, we propose a deep spatio-temporal forecasting model (DeepSTF) for multi-site weather prediction post-processing by using both temporal andspatial information. In our proposed framework, the spatio-temporal information ismodeled by a CNN (convolutional neural network) module and an encoder-decoderstructure with the attention mechanism. The novelty of our work lies in that our modeltakes full account of temporal and spatial characteristics and obtain forecasts of multiple meteorological stations simultaneously by using the same framework. We applythe DeepSTF model to short-term weather prediction at 226 meteorological stations inBeijing. It significantly improves the short-term forecasts compared to other widelyused benchmark models including the Model Output Statistics method. In order toevaluate the uncertainty of the model parameters, we estimate the confidence intervals by bootstrapping. The results show that the prediction accuracy of the DeepSTFmodel has strong stability. Finally, we evaluate the impact of seasonal changes and topographical differences on the accuracy of the model predictions. The results indicatethat our proposed model has high prediction accuracy.Wenjia Kong Haochen Li Chen Yu Jiangjiang Xia Yanyan Kang Pingwen Zhang 2022Communications in Computational Physics2022,31,1:1
10Bimetallic NiCo2S4 Nanoneedles Anchored on Mesocarbon Microbeads as Advanced Electrodes for Asymmetric Supercapacitors显示文摘Bimetallic Ni–Co sulfides are outstanding pseudocapacitive materials with high electrochemical activity and excellent energy storage performance as electrodes for high-performance supercapacitors.In this study,a novel urchin-like NiCo2S4@mesocarbon microbead(NCS@MCMB) composite with a core–shell structure was prepared by a facile two-step hydrothermal method.The highly conductive MCMBs offered abundant adsorption sites for the growth of NCS nanoneedles,which allowed each nanoneedle to fully unfold without aggregation,resulting in improved NCS utilization and efficient electron/ion transferin the electrolyte.When applied as an electrode material for supercapacitors,the composite exhibited a maximum specific capacitance of 936 Fg-1 at 1 Ag-1 and a capacitance retention of 94% after 3000 cycles at 5 Ag-1,because of the synergistic effect of MCMB and NCS.Moreover,we fabricated an asymmetric supercapacitor based on the NCS@MCMB composite,which exhibited enlarged voltage windows and could power a light-emitting diode device for several minutes,further demonstrating the exceptional electrochemical performance of the NCS@MCMB composite.Yu Zhang Yihe Zhang Yuanxing Zhang Haochen Si Li Sun 2019Nano-Micro Letters2019,11,2:1
11A station-data-based model residual machine learning method for fine-grained meteorological grid prediction显示文摘Fine-grained weather forecasting data,i.e.,the grid data with high-resolution,have attracted increasing attention in recent years,especially for some specific applications such as the Winter Olympic Games.Although European Centre for Medium-Range Weather Forecasts(ECMWF)provides grid prediction up to 240 hours,the coarse data are unable to meet high requirements of these major events.In this paper,we propose a method,called model residual machine learning(MRML),to generate grid prediction with high-resolution based on high-precision stations forecasting.MRML applies model output machine learning(MOML)for stations forecasting.Subsequently,MRML utilizes these forecasts to improve the quality of the grid data by fitting a machine learning(ML)model to the residuals.We demonstrate that MRML achieves high capability at diverse meteorological elements,specifically,temperature,relative humidity,and wind speed.In addition,MRML could be easily extended to other post-processing methods by invoking different techniques.In our experiments,MRML outperforms the traditional downscaling methods such as piecewise linear interpolation(PLI)on the testing data.Chuansai ZHOU Haochen LI Chen YU Jiangjiang XIA Pingwen ZHANG 2022Applied Mathematics and Mechanics(English Edition)2022,43,2:0
12Introduction to bioimaging-based spatial multi-omic novel methods显示文摘Background: Spatial multi-omics are demonstrated to be a powerful method to assist researchers on genetic studies. In this review, bioimaging-based spatial multi-omics techniques such as seqFISH+, merFISH, integrated DNA seqFISH+, DNA merFISH, and MINA are introduced along with each technique’s probe design, development, and imaging processes.Results: seqFISH employed 4–5 fluorophores to barcode and conducted multiple rounds of hybridization, in order that mRNA can be identified through color-coding. seqFISH+ added 60 pseudo-color and distributed them equally into three channels to enhance imaging power, in order that i.e., 24,000 genes can be imaged in total. merFISH utilized 4 out 16 Hamming distance to innovatively provide a robust error-detecting method. MINA, a methodology combining merFISH (multiplexed error-robust fluorescence in situ hybridization) and chromosomal tracing, enabled multiplexed genomic architecture imaged in mammalian single cells. Optical reconstruction of chromatin architecture (ORCA) a method that could conduct DNA path tracing in nanoscale manner with kilobase resolution, an FISH variation that improved genetic resolution, enable high-precision fiducial registration and sequential imaging, and utilized Oligopaint probe to hybridize the short genomic region ranging from 2 to 10 kilobase. ORCA then prescribes these short section primary probes with individual barcodes to attach fluorophore and to be imaged.Conclusion: This review concentrated on providing a comprehensive overview for these spatial-multi-omics techniques with the intention on helping researchers on selecting appropriate technique for their research.Yan Yan Liheng Yang Leyuan Meng Haochen Su Cheng Zhou Le Yu Zhengtu Li Xu Zhang Huihua Cai Juntao Gao 2023Quantitative Biology2023,11,3:0
13Enhancement of T cell infiltration via tumor-targeted Th9 cell delivery improves the efficacy of antitumor immunotherapy of solid tumors显示文摘Insufficient infiltration of T cells severely compromises the antitumor efficacy of adoptive cell therapy(ACT)against solid tumors.Here,we present a facile immune cell surface engineering strategy aiming to substantially enhance the anti-tumor efficacy of Th9-mediated ACT by rapidly identifying tumor-specific binding ligands and improving the infiltration of infused cells into solid tumors.Non-genetic decoration of Th9 cells with tumor-targeting peptide screened from phage display not only allowed precise targeted ACT against highly heterogeneous solid tumors but also substantially enhanced infiltration of CD8+T cells,which led to improved antitumor outcomes.Mechanistically,infusion of Th9 cells modified with tumor-specific binding ligands facilitated the enhanced distribution of tumor-killing cells and remodeled the immunosuppressive microenvironment of solid tumors via IL-9 mediated immunomodulation.Overall,we presented a simple,cost-effective,and cell-friendly strategy to enhance the efficacy of ACT against solid tumors with the potential to complement the current ACT.Tao Chen Yucheng Xue Shengdong Wang Jinwei Lu Hao Zhou Wenkan Zhang Zhiyi Zhou Binghao Li Yong Li Zenan Wang Changwei Li Yinwang Eloy Hangxiang Sun Yihang Shen Mohamed Diaty Diarra Chang Ge Xupeng Chai Haochen Mou Peng Lin Xiaohua Yu Zhaoming Ye 2023Bioactive Materials2023,,5:0
14Disturbance rejection for biped robots during walking and running using control moment gyroscopes显示文摘Keeping balance in movement is an important premise for biped robots to complete various tasks.Now,the balance control of biped robots mainly depends on the cooperation of various joints of the robot's body.When robots move faster,the adjustment allowance of joints is reduced,and the robot's anti-disturbance ability will inevitably decline.To solve this problem,the control moment gyroscope(CMG)is creatively used as an auxiliary stabilisation device for fully actuated biped robots and the CMG assistance strategy,which can be integrated into the biped's balance control framework,is proposed.This strategy includes model predictive control module,distribution module,and CMG precession controller.Under the command of it,CMGs can effectively assist the robot in resisting impact and returning to initial positions in time.The results of anti-impact simulation on the walking and running biped robot prove that,with the help of CMGs,the robot's ability to resist disturbance and remain stable is significantly improved.The cover image is based on the Original Article Disturbance rejection for biped robots during walking and running using control moment gyroscopes by Haochen Xu et al.,http://gffzzd3cc09b8251d45dfsokx9wc9cvcu06u59.ffgz.tsg.suse.edu.cn/10.1049/csy2.12070.Haochen Xu Zhangguo Yu Xuechao Chen Chencheng Dong Huanzhong Chen Qiang Huang 2022IET Cyber-Systems and Robotics2022,4,4:0
15Spatio-temporal Variation of Distribution Patterns in Cunninghamia lanceolata Plantations显示文摘To aid in management of Cunninghamia lanceolata,the main timber species in Southern China,its variation of spatial distribution pattern was analyzed.Three permanent plots of C.lanceolata plantations with approximately the same site conditions,set by China continuous forest inventory in Shunchang,Fujian,were selected. C.lanceolata growth was divided into two stages: young trees(5 cm≤diameter at breast height (DBH)<10 cm) and mature trees(DBH≥10 cm). The DBH and coordinates of every tree(DBH≥5 cm) in the permanent plots were recorded in 2003 and 2008.The function L(r),improvement of Ripley’s K(r),the paircorrelation function g(r),and the uniform angle index(W_i) were used to analyze the spatio-temporal variation of spatial distribution patterns.The three permanent plots had mean uniform angle index(W) between 0.494-0.578 at low altitudes,0.465-0.477 at medium altitudes,and 0.426-0.601 at high altitudes.Results showed that altitude did not affect the spatial distribution pattern. The L(r ) and g(r) function curves of mature trees were generally lower than young trees’,i.e.tend to be more random or uniform distribution.So regardless of the initial distribution of young or mature trees,with the passage of time,there was a tendency for the aggregated distribution to change to a random distribution,and a random distribution to change to a uniform distribution.Yang Ziqing Chen Pingliu Liu Jian Yu Kunyong Liao Xiaoli You Haochen Gong Conghong 2012Chinese Forestry Science and Technology2012,11,3:0
16Boosted high-temperature electrical characteristics of AlGaN/GaN HEMTs with rationally designed compositionally graded AlGaN back barriers显示文摘Wide bandgap GaN-based HEMTs have shown great potential as key components in various power electronic systems but still face challenges in the pursuit of devices with stable operation capability especially in harsh environments.Here,we report a high-performance double heterojunction(DH)based AlGaN/GaN HEMT by incorporating a decreasing-Al-composition(DAC)graded AlGaN back barrier(BB)beneath the GaN channel.Thanks to the improved electron confinement enabled by graded BB,the DHHEMT exhibits significantly improved on-state drain current density and off-state breakdown voltage compared with a single heterojunction(SH)based HEMT.More intriguingly,with an additional Si Nx passivation layer,the surface states of the DH-HEMTs can be effectively suppressed,leading to an almost constant offstate leakage current and negligible gate contact degradation across the temperature range from 25℃to 150℃.These results highlight the superiority and reliability of the proposed graded AlGaN BB to boost device characteristics for applications under high temperatures and harsh conditions.Haochen ZHANG Yue SUN Kunpeng HU Lei YANG Kun LIANG Zhanyong XING Hu WANG Mingshuo ZHANG Huabin YU Shi FANG Yang KANG Haiding SUN 2023Science China(Information Sciences)2023,66,8:0
17Observation of polarity-switchable photoconductivity in lInitride/MoS_(x)core-shell nanowires显示文摘Ⅱ-Ⅴsemiconductor nanowires are indispensable building blocks for nanoscale electronic and optoelectronic devices.However,solely relying on their intrinsic physical and material properties sometimes limits device functionalities to meet the increasing demands in versatile and complex electronic world.By leveraging the distinctive nature of the one-dimensional geometry and large surface-to-volume ratio of the nanowires,new properties can be attained through monolithic integration of conventional nanowires with other easy-synthesized functional materials.Herein,we combine high-crystal-quality lInitridle nanowires with amorphous molybdenum sulfides(a-MoS)to construct II.nitride/a-MoS_(x) core-shell nanostructures.Upon light ilumination,such nanostructures exhibit striking spectrally distinctive photodetection characteristic in photoelectrochemical environment,demonstrating a negative photoresponsivity of-100.42 mA W^(-1)under 254 nm ilumination,and a positive photoresponsivity of 29.5 mA W^(-1)under 365 nm ilumination.Density functional theory calculations reveal that the successful surface modifcation of the nanowires via a-MoS_(x)decoration accelerates the reaction process at the electrolyte/nanowire interface,leading to the generation of opposite photocurrent signals under different photon ilumination.Most importantly,such polarity-switchable photoconductivity can be further tuned for multiple wavelength bands photodetection by simply adjusting the surrounding environment and/or tailoring the nanowire composition,showing great promise to build light-wavelength controllable sensing devices in the future.Danhao Wang Wentiao Wu Shi Fang Yang Kang Xiaoning Wang Wei Hu Huabin Yu Haochen Zhang Xin Lu Yuanmin Luo Jr-Hau He Lan Fu Shibing Long Sheng Liu Haiding Sun 2022Light(Science & Applications)2022,11,11:0
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