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| 1 | 基质相互作用分子1基因与妊娠期高血压疾病的相关性:病例对照研究显示文摘妊娠期高血压疾病(hypertensive disorders of pregnancy,HDP)是一种常见疾病,并被认为是一种多因素遗传疾病。先前研究报道,基质相互作用分子1(stromal interaction molecule 1,STIM1)参与调节Ca^(2+)浓度和血管收缩。该研究的目的是通过病例对照研究来评估HDP与人类STIM1基因单核苷酸多态性(single-nucleotide polymorphisms,SNP)或单体型之间的关系。 | 刘青 叶鹏 Shinya K Nakayama T Yamamoto T | 2018 | 中华高血压杂志2018，26，1： | 6 |
| 2 | In vitro anti-human immunodeficiency virus activity of polysaccharide from Rhizophora mucronata 显示文摘 | Premanathan M Kathiresan K Yamamoto N | 1999 | Biosci Biotechnol Biochem1999，63，7： | 2 |
| 3 | Control of volatile organic compounds by an AC energized ferroelectric pellet reactor and a pulsed corona reactor显示文摘 | Yamamoto K Ramanathan P A Lawless | 1992 | IEEE Trans Ind Applicat1992，28，2： | 2 |
| 4 | Inhibition of antithrombin by hyaluronic acid may be involved in the pathogenesis of rheumatoid arthritis显示文摘 | Chang X Yamada R Yamamoto K | | Arthritis Research & Therapy0，，： | 2 |
| 5 | Preparation of thermostable and electric-conducting poly(2,5-thienylene) 显示文摘 | Yamamoto T Sanechika K Yamamoto A | 1980 | J Polym Sci Polym Lett Ed1980，18，： | 2 |
| 6 | Carbon catalyzed supercritical water oxidation of phenol 显示文摘 | Matsumura Y Urase T Yamamoto K | 2002 | Journal of Supercritical Fluids2002，22，3： | 2 |
| 7 | Effect of Boron onIntra-Granular Ferrite Formation in Ti-Oxide Bearing Steels显示文摘 | Yamamoto K Hasegawa T Takamura J | 1996 | ISIJ Int1996，36，1： | 2 |
| 8 | 胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。 | Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 | 2017 | 中华高血压杂志2017，25，9： | 2 |
| 9 | 初产妇和经产妇妊娠期间的诊室和家庭血压显示文摘妊娠高血压可导致分娩时产生严重的并发症,如脑卒中、早产或低出生体质量。初产妇被认为是妊娠高血压的一个危险因素。产次与妊娠期间家庭血压相关性仍不明确。方法:入选初产妇和经产妇共575名,评估妊娠高血压和先兆子痫的发病率。收集在一家日本产科医院接受产前检查的530名正常血压孕妇的家庭和诊室血压值。诊室血压为产前检查2次测量的血压平均值,参与者妊娠期间每日清晨在家自测血压。 | Ishikuro M Obara T Metoki H Ohkubo T Yamamoto M Akutsu K Sakurai K Iwama N Katagiri M Yagihashi K Yaegashi N Mori S Suzuki M Kuriyama S Imai Y 罗冬梅 叶鹏 | 2013 | 中华高血压杂志2013，21，6： | 2 |
| 10 | Protective effect of Irsogladine on monochloramineinduced gastric mucosallesions in rats:a comparative study with rebamipide显示文摘AIM To examine the effect of irsogladine, a novel antiulcer drug, on the mucosal ulcerogenic response to monochloramine (NH 2Cl) in rat stomach, in comparison with rebamipide, another antiulcer drug with cytoprotective activity. METHODS AND RESULTS Oral administration of NH 2Cl (120*!mM) produced severe hemorrhagic lesions in unanesthetized rat stomachs. Both irsogladine ( 1*!mg/*!kg - 10*!mg/*!kg , po ) and rebamipide ( 30*!mg/*!kg - 100*!mg/*!kg , po ) dose dependently prevented the development of these lesions in response to NH 2Cl, the effect of irsogladine was significant at 3*!mg/*!kg or greater, and that of rebamipide only at 100*!mg/*!kg . The protective effect of irsogladine on NH 2Cl induced gastric lesions was significantly reduced by N G nitro L arginine methyl ester (L NAME) but not by indomethacin, while that of rebamipide was significantly mitigated by indomethacin but not by L NAME. Topical application of NH 2Cl (20*!mM) caused a marked reduction of potential difference (PD) in ex vivo stomachs. This PD reduction was not affected by mucosal application of irsogladine, but significantly prevented by rebamipide. The mucosal exposure to NH 4OH (120*!mM) also caused a marked PD reduction in the ischemic stomach (bleeding from the carotid artery), resulting in gastric lesions. These ulcerogenic and PD responses caused by NH 4OH plus ischemia were also significantly mitigated by rebamipide, in an indomethacin sensitive manner, while irsogladine potently prevented such lesions without affecting the PD response, in a L NAME sensitive manner. CONCLUSION These results suggest that ① NH 2Cl generated either exogenously or endogenously damages the gastric mucosa, ② both irsogladine and rebamipide protect the stomach against injury caused by NH 2Cl, and ③ the mechanism underlying the protective action of irsogladine is partly mediated by endogenous nitric oxide, while that of rebamipide is in part mediated by endogenous prostaglandins. | H Yamamoto, M Umeda, H Mizoguchi, S Kato and K Takeuchi | 1999 | World Journal of Gastroenterology1999，5，6： | 2 |
| 11 | Hybrid OVSF code assignment scheme in W-CDMA, IEEE Pacific RIM conference on communications 显示文摘 | Sekine Y Kawanishi K Yamamoto U | 2003 | Computers and Signal Processing-Proceedings2003，，1： | 2 |
| 12 | Development of a new tool material to ensure high performance in hot steel rolling显示文摘 | Tsubouchi K Akiyama M Yamamoto E | 1999 | Journal of tribology1999，121，4： | 2 |
| 13 | Denitrification with Methane as External Carbon Source显示文摘 | MODIN O FUKUSHI K YAMAMOTO K | 2007 | Water Res2007，41，12： | 1 |
| 14 | Parentage analysis in Japanese peaches using SSR markers 显示文摘 | Yamamoto T Mochida K Imai T | 2003 | Breeding Science2003，53，1： | 1 |
| 15 | Antioxidative properties of Jaffa sweeties and grapefruit and their influence on lipid metabolism and plasma antioxidative potential in rats显示文摘 | Gorinstein S Yamamoto K Katrich E | 2003 | Biosci Biotechnol Biochem2003，67，： | 1 |
| 16 | 3-D Thermodynamic Analysis of Superhydrophobic Surfaces 显示文摘 | Yamamoto K Ogata S | 2008 | J Colloid Interface Sci2008，326，2： | 1 |
| 17 | c-kit and PDGFRA mutations in extragastrointestinal stromal tumor (gastrointestinal stromal tumor of the soft tissue)显示文摘 | Yamamoto H Oda Y Kawaguchi K | 2004 | Am J Surg Pathol2004，28，4： | 1 |
| 18 | Effects of the oxide laver formed on TiN coated silicon wafer on the friction and wear characteristics in dry sliding 显示文摘 | Zhou Y M Asaki R Yamamoto K R | 2003 | Surface and Coatings Technology2003，168，1： | 1 |
| 19 | Cerebral ischemia in the gerbil transmission electron microscopic and immunoelectron microscopic investigation显示文摘 | Morimoto K Yanagihara T | 1986 | Brain Res1986，384，1： | 1 |
| 20 | Predisposing factors to enlargement of spontaneous intracerebral hematomas显示文摘 | Minematsu K Yamamoto H | 1997 | Stroke1997，28，： | 1 |
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