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| 1 | Sedum alfredii H:A new Zn hyperaccumulating plant first found in China显示文摘Field survey and greenhouse experiments were carried out to identify and characterize zinc (Zn) uptake and accumulation by a new Zn hyperaccumulating plant species (Sedum alfredii Hance) native to China. Zinc concentration in the shoots of Sedum alfredii Hance grown on an ancient mined area ranged from 4134 to 5000 mg/kg, with a mean of 4515 mg/kg. It suggests that Sedum alfredii could not only grow on heavily Pb/Zn contaminated soils, but also could accumulate extraordinarily high concentration of Zn. Under nutrient solution culture conditions, Sedum alfredii Hance grew healthy at Zn supplying levels from 0.006 to 240 mg · L-1. Zinc concentration in the shoots increased with external Zn levels increasing. The Zn concentration and accumulation in the shoots reached the highest at Zn supply level of SO mg/L, with 19.67 g/kg and 19.83 nig/plant, respectively. All the results showed that Sedum alfredii Hance is a new Zn hyperaccumulating plant. This provides a new plant material to explore mechanism of | YANG Xiao’e LONG Xinxian NI Wuzhong FU Chenxin | 2002 | Chinese Science Bulletin2002，47，19： | 50 |
| 2 | Geochemical and Pb-Sr-Nd isotopic compositions of Indosinian granitoids from the Bikou block,northwest of the Yangtze plate:Constraints on petrogenesis,nature of deep crust and geodynamics显示文摘This paper reports geochemical and Pb-Sr-Nd isotopic compositions of the Indosinian Yangba (215 Ma),Nanyili (225 Ma) and Mopi granitoids from the Bikou block of the northwestern margin of the Yangtze plate. These granitoids are enriched in Al (Al2O3:14.56%―16.48%) and Sr (352 μg/g―1047 μg/g),and depleted in Y (<16 μg/g) and HREE (e.g. Yb<1.61 μg/g),resulting in high Sr/Y (36.3―150) and (La/Yb)N (7.8―36.3) ratios and strongly fractionationed REE patterns. The Indosinian granotoids show initial Sr isotopic ratios (ISr) from 0.70419 to 70752,εNd(t) values from-3.1 to -8.5,and initial Pb isotopic ratios 206Pb/204Pb=17.891-18.250,207Pb/204Pb=15.494-15.575,and 208Pb/204Pb=37.788-38.335. Their geochemi-cal signatures indicate that the granitoids are adakitic. However,they are distinct from some adakites,generated by partial melting of subducted oceanic slab and/or underplated basaltic lower crust,be-cause they have high K (K2O: 1.49%―3.84%) and evolved Nd isotopic compositions,with older Nd iso-topic model ages (TDM=1.06―1.83 Ga). Geochemical and Sr-Nd isotopic compositions suggest that the magmas of the Insoninian adakitic rocks in the Bikou block were derived from partial melting of thick-ened basaltic lower crust. Combined with regional analyses,a lithospheric delamination model after collision between the North China and South China plates can account for the Indosinian adakitic magma generation. On the other hand,based on the Pb-Sr-Nd isotopic probing to the magma sources of the adakitic rocks,it is suggested that there is an unexposed continent-type basement under the exposed Bikou Group volcanic rocks. This can constrain on the Bikou Group volcanic rocks not to be MORB-or OIB-type. | ZHANG HongFei XIAO Long ZHANG Li YUAN HongLin JIN LanLan | 2007 | Science China Earth Sciences2007，50，7： | 38 |
| 3 | Early Paleozoic ridge subduction in the Chinese Altai: Insight from the abrupt change in zircon Hf isotopic compositions显示文摘Zircons were separated from granitoids, gneisses, and sedimentary rocks of the Chinese Altai. Those with igneous characteristics yielded U-Pb ages of 280-2800 Ma, recording a long history of magmatic activity in the region. Zircon Hf isotopic compositions show an abrupt change at ~420 Ma, indicating that prior to that time the magmas came from both ancient and juvenile sources, whereas younger magmas were derived mainly from juvenile material. This may imply that the lithosphere was signifi- cantly modified in composition by a rapid addition of melt from the mantle. We suggest that this dramatic change was due to the onset of ridge subduction, which can account not only for the formation of voluminous granitoids, mafic rocks with complex compositions, and the association of adakite + high-Mg andesite + boninite + Nb-enriched basalt, but also for the coeval high-T, low-P metamorphism. | SUN Min LONG XiaoPing CAI KeDa JIANG YingDe WANG BuYun YUAN Chao ZHAO GuoChun XIAO WenJiao WU FuYuan | 2009 | Science China Earth Sciences2009，52，9： | 33 |
| 4 | Major element,trace element,and Sr,Nd and Pb iso-tope studies of Cenozoic basalts from the South China Sea显示文摘The whole rock K-Ar ages of basalts from the South China Sea basin vary from 3.8 to 7.9 Ma, which suggest that intra-plate volcanism after the cessation of spreading of the South China Sea (SCS) is comparable to that in adjacent regions around the SCS, i.e., Leiqiong Peninsula, northern margin of the SCS, Indochina block, and so on. Based on detailed petrographic studies, we selected many fresh ba-saltic rocks and measured their major element, trace element, and Sr-Nd-Pb isotope compositions. Geochemical characteristics of major element and trace element show that these basaltic rocks belong to alkali basalt magma series, and are similar to OIB-type basalt. The extent of partial melting of mantle rock in source region is very low, and magma may experience crystallization differentiation and cu-mulation during the ascent to or storing in the high-level magma chamber. Sr-Nd-Pb isotopic data of these basaltic rocks imply an inhomogeneous mantle below the South China Sea. The nature of magma origin has a two end-member mixing model, one is EM2 (Enriched Mantle 2) which may be originated from mantle plume, the other is DMM (Depleted MORB Mantle). Pb isotopic characteristics show the Dupal anomaly in the South China Sea, and combined with newly found Dupal anomaly at Gakkel ridge in Arctic Ocean, this implies that Dupal anomaly is not only limited to South Hemisphere. In variation diagrams among Sr, Nd and Pb, the origin nature of mantle below the SCS is similar to those below Leiqiong peninsula, northern margin of the SCS and Indochina peninsula, and is different from those below north and northeast China. This study provides geochemical constraints on Hainan mantle plume. | YAN QuanShu SHI XueFa WANG KunShan BU WenRui XIAO Long | 2008 | Science China Earth Sciences2008，51，4： | 33 |
| 5 | Recent advances in friction and lubrication of graphene and other 2D materials:Mechanisms and applications显示文摘Two-dimensional materials having a layered structure comprise a monolayer or multilayers of atomic thickness and ultra-low shear strength.Their high specific surface area,in-plane strength,weak layer-layer interaction,and surface chemical stability result in remarkably low friction and wear-resisting properties.Thus,2D materials have attracted considerable attention.In recent years,great advances have been made in the scientific research and industrial applications of anti-friction,anti-wear,and lubrication of 2D materials.In this article,the basic nanoscale friction mechanisms of 2D materials including interfacial friction and surface friction mechanisms are summarized.This paper also includes a review of reports on lubrication mechanisms based on the film-formation,self-healing,and ball bearing mechanisms and applications based on lubricant additives,nanoscale lubricating films,and space lubrication materials of 2D materials in detail.Finally,the challenges and potential applications of 2D materials in the field of lubrication were also presented. | Lincong LIU Ming ZHOU Long JIN Liangchuan LI Youtang MO Guoshi SU Xiao LI Hongwei ZHU Yu TIAN | 2019 | Friction2019，7，3： | 29 |
| 6 | Combined detection of serum tumor markers for differential diagnosis of solid lesions located at the pancreatic head显示文摘BACKGROUND: The differential diagnosis of solid lesions located at the pancreatic head is very important for choosing therapies and setting up surgical tactics. This study was designed to evaluate the clinical significance of combined measurement of multiple serum tumor markers and the application of the receiver-operating characteristic (ROC) curves in the differential diagnosis of solid lesions located at the pancreatic head. METHODS: The serum levels of CA19-9, CA242, CA50 and carcinoembryonic antigen (CEA) in 112 patients with carcinoma of the pancreatic head and 38 patients with focal chronic pancreatitis in the pancreatic head were measured with ELISA. The sensitivity, specificity, positive likelihood ratio (PLR) and negative likelihood ratio (NLR) of the four serum tumor markers were calculated. The ROC curves for the four serum tumor markers were constructed and the area under the curve (AUC) was calculated. RESULTS: The AUCs of CA19-9, CA242, CA50 and CEA were 0.805, 0.749, 0.738 and 0.705; the PLRs were 1.91, 3.43, 5.09 and 5.46; and the NLRs were 0.41, 0.56, 0.59 and 0.71, respectively. Combined measurements increased the diagnostic specificity, and parallel combined testing increased the diagnostic sensitivity. CONCLUSIONS: Combined measurement of serum tumor markers CA19-9, CA242, CA50 and CEA is valuable in differential diagnosis of solid lesions located at the pancreatic head, and CA19-9 has the best diagnostic ability. Combined measurements can increase the specificity ofdiagnosis. Evaluation with the ROC curve is better than the sensitivity or specificity alone and the results are more integrated and objective. | Liao, Quan Zhao, Yu-Pei Yang, Ying-Chi Li, Li-Jun Long, Xiao Han, Shao-Mei | 2007 | Hepatobiliary & Pancreatic Diseases International2007，6，6： | 27 |
| 7 | Radiation Therapy in Keloids Treatment: History, Strategy,Effectiveness, and Complication显示文摘 | Jing Xu Elan Yang Nan-Ze YU Xiao Long | 2017 | Chinese Medical Journal2017，，14： | 22 |
| 8 | Optimal allocation of multi-type FACTS devices in power systems based on power flow entropy显示文摘Flexible AC transmission systems(FACTS)devices can effectively optimize the distribution of power flow.Power flow entropy can be applied as a measure of load distribution.In this paper,a method is proposed to optimize the distribution of power flow with the coordination of multi-type FACTS devices and establishes the corresponding mathematical models.The modified group searcher optimization(GSO)algorithm is proposed,in which the angle search is combined with chaotic search model to avoid jumping into local optimization.Compared with the different optimal allocation of multi-FACTS devices,the optimal allocation of multi-FACTS devices is achieved under the economic constraints.The locations obtained by this method can achieve the purpose of balancing power flow and enhancing the system performances.The simulations are demonstrated in an IEEE 118-bus power system with two classical types of FACTS,namely static var compensator(SVC)and thyristor controlled series Compensator(TCSC).The simulation results show that the proposed method is feasible and effective. | Canbing LI Liwu XIAO Yijia CAO Qianlong ZHU Baling FANG Yi TAN Long ZENG | 2014 | Journal of Modern Power Systems and Clean Energy2014，2，2： | 23 |
| 9 | Synthesis of novel nanomaterials and their application in efficient removal of radionuclides显示文摘With the development of nuclear energy, large amounts of radionuclides are inevitably released into the natural environment. It is necessary to eliminate radionuclides from wastewater for the protection of environment. Nanomaterials have been considered as the potential candidates for the effective and selective removal of radionuclides from aqueous solutions under complicated conditions because of their high specific surface area, large amounts of binding sites, abundant functional groups, pore-size controllable and easily surface modification. This review mainly summarized the recent studies for the synthesis, fabrication and surface modification of novel nanomaterials and their applications in the efficient elimination and solidification of radionuclides,and discussed the interaction mechanisms from batch experiments, spectroscopy analysis and theoretical calculations. The sorption capacities with other materials, advantages and disadvantages of different nanomaterials are compared, and at last the perspective of the novel nanomaterials is summarized. | Xiangxue Wang Long Chen Lin Wang Qiaohui Fan Duoqiang Pan Jiaxing Li Fangting Chi Yi Xie Shujun Yu Chengliang Xiao Feng Luo Jun Wang Xiaolin Wang Changlun Chen Wangsuo Wu Weiqun Shi Shuao Wang Xiangke Wang | 2019 | Science China Chemistry2019，62，8： | 20 |
| 10 | Clinical trial with traditional Chinese medicine intervention ''tonifying the kidney to promote liver regeneration and repair by affecting stem cells and their microenvironment'' for chronic hepatitis B-associated liver failure显示文摘AIM:To study the clinical efficacy of traditional Chinese medicine(TCM)intervention'tonifying the kidney to promote liver regeneration and repair by affecting stem cells and their microenvironment'('TTK')for treating liver failure due to chronic hepatitis B.METHODS:We designed the study as a randomized controlled clinical trial.Registration number of Chinese Clinical Trial Registry is Chi CTR-TRC-12002961.A total of 144 patients with liver failure due to infection with chronic hepatitis B virus were enrolled in this randomized controlled clinical study.Participants were randomly assigned to the following three groups:(1)a modern medicine control group(MMC group,36patients);(2)a'tonifying qi and detoxification'('TQD')group(72 patients);and(3)a'tonifying the kidney to promote liver regeneration and repair by affecting stem cells and their microenvironment'('TTK')group(36patients).Patients in the MMC group received general internal medicine treatment;patients in the'TQD'group were given a TCM formula'tonifying qi and detoxification'and general internal medicine treatment;patients in the'TTK'group were given a TCM formula of'TTK'and general internal medicine treatment.All participants were treated for 8 wk and then followed at 48 wk following their final treatment.The primaryefficacy end point was the patient fatality rate in each group.Measurements of various virological and biochemical indicators served as secondary endpoints.The one-way analysis of variance and the t-test were used to compare patient outcomes in the different treatment groups.RESULTS:At the 48-wk post-treatment time point,the patient fatality rates in the MMC,'TQD',and'TTK'groups were 51.61%,35.38%,and 16.67%,respectively,and the differences between groups were statistically significant(P<0.05).However,there were no significant differences in the levels of hepatitis B virus DNA or prothrombin activity among the three groups(P>0.05).Patients in the'TTK'group had significantly higher levels of serum total bilirubin compared to MMC subjects(339.40μmol/L±270.09μmol/L vs 176.13μmol/L±185.70μmol/L,P=0.014).Serum albumin levels were significantly increased in both the'TQD'group and'TTK'group as compared with the MMC group(31.30 g/L±4.77g/L,30.72 g/L±2.89 g/L vs 28.57 g/L±4.56 g/L,P<0.05).There were no significant differences in levels of alanine transaminase among the three groups(P>0.05).Safety data showed that there was one case of stomachache in the'TQD'group and one case of gastrointestinal side effect in the'TTK'group.CONCLUSION:Treatment with'TTK'improved the survival rates of patients with liver failure due to chronic hepatitis B.Additionally,liver tissue was regenerated and liver function was restored. | Han-Min Li Zhi-Hua Ye Jun Zhang Xiang Gao Yan-Ming Chen Xin Yao Jian-Xun Gu Lei Zhan Yang Ji Jian-Liang Xu Ying-He Zeng Fan Yang Lin Xiao Guo-Guang Sheng Wei Xin Qi Long Qing-Jing Zhu Zhao-Hong Shi Lian-Guo Ruan Jia-Yao Yang Chang-Chun Li Hong-Bin Wu Sheng-Duo Chen Xin-La Luo | 2014 | World Journal of Gastroenterology2014，20，48： | 20 |
| 11 | Efects of a bioartificial liver support system on a cetaminophen-induced acute liver failure canines显示文摘Seeinvitedcommentaryonpage286Subjectheadingsliversupportsystem;acuteliverfailure;canines;porcinehepatocytes;bioartificiallive... | XUE Yi Long 1, ZHAO Shi Feng 2, ZHANG Zuo Yun 1, WANG Yue Feng 1, LI Xin Jian 1, HUANG Xiao Qiang 3, LUO Yun 1, HUANG Ying Cai 4 and LIU Cheng Gui 1 | 1999 | World Journal of Gastroenterology1999，5，4： | 19 |
| 12 | A new approach to consensus problems in discrete-time multiagent systems with time-delays显示文摘In this paper, consensus problems in discrete-time multiagent systems with time-invariant delays are considered. In order to characterize the structures of communication topologies, the concept of 'pre-leader-follower' decomposition is introduced. Then, a necessary and sufficient condition for state consensus is established. By this method, consensus problems in networks with a single time-delay, as well as with multiple time-delays, are studied, and some necessary and sufficient conditions for solvability of consensus problems are obtained. | WANG Long XIAO Feng | 2007 | Science in China(Series F)2007，50，4： | 19 |
| 13 | Expediting redox kinetics of sulfur species by atomic-scale electrocatalysts in lithium–sulfur batteries显示文摘Lithium–sulfur(Li–S)batteries have extremely high theoretical energy density that make them as promising systems toward vast practical applications.Expediting redox kinetics of sulfur species is a decisive task to break the kinetic limitation of insulating lithium sulfide/disulfide precipitation/dissolution.Herein,we proposed a porphyrinderived atomic electrocatalyst to exert atomic-efficient electrocatalytic effects on polysulfide intermediates.Quantifying electrocatalytic efficiency of liquid/solid conversion through a potentiostatic intermittent titration technique measurement presents a kinetic understanding of specific phase evolutions imparted by the atomic electrocatalyst.Benefiting from atomically dispersed“lithiophilic”and“sulfiphilic”sites on conductive substrates,the finely designed atomic electrocatalyst endows Li–S cells with remarkable cycling stablity(cyclic decay rate of 0.10%in 300 cycles),excellent rate capability(1035 mAh g−1 at 2 C),and impressive areal capacity(10.9 mAh cm−2 at a sulfur loading of 11.3 mg cm−2).The present work expands atomic electrocatalysts to the Li–S chemistry,deepens kinetic understanding of sulfur species evolution,and encourages application of emerging electrocatalysis in other multielectron/multiphase reaction energy systems. | Bo-Quan Li Long Kong Chang-Xin Zhao Qi Jin Xiao Chen Hong-Jie Peng Jin-Lei Qin Jin-Xiu Chen Hong Yuan Qiang Zhang Jia-Qi Huang | 2019 | InfoMat2019，1，4： | 18 |
| 14 | Effectiveness of Different Waist Circumference Cut-off Values in Predicting Metabolic Syndrome Prevalence and Risk Factors in Adults in China显示文摘Objective To study the effectiveness of waist circumference cut-off values in predicting the prevalence of metabolic syndrome(MetS) and risk factors in adults in China. Methods A cross-sectional survey was condcuted in 14 provinces(autonomous region, municipality) in China. A total of 47 325 adults aged ≥20 years were selected by multistage stratified sampling, and questionnaire survey and physical and clinical examination were conducted among them. MetS was defined according to the International Diabetes Federation(IDF) criteria and modified IDF criteria.Results The age-standardized prevalence of MetS was 24.2%(22.1% in men and 25.8% in women) and 19.5%(22.1% in men and 18.0% in women) according to the IDF criteria and modified IDF criteria respectively. The age-standardized prevalence of pre-MetS was 8.1%(8.6% in men and 7.8% in women) according to the modified IDF criteria. The prevalence of MetS was higher in urban residents than rural residents and in northern China residents than in southern China residents. The prevalence of central obesity was about 30% in both men and women according to the ethnicity-specific cut-off values of waist circumference for central obesity(90 cm for men and 85 cm for women). Multivariate regression analysis revealed no significant difference in risk factors between the two MetS definitions. Conclusion Using both the modified IDF criteria and ethnicity-specific cut-off values of waist circumference can provide more useful information about the prevalence of MetS in China. | ZHOU Hai Cheng LAI Ya Xin SHAN Zhong Yan JIA Wei Ping YANG Wen Ying LU Ju Ming WENG Jian Ping JI Li Nong LIU Jie TIAN Hao Ming JI Qiu He ZHU Da Long CHEN Li GUO Xiao Hui ZHAO Zhi Gang Li Qiang ZHOU Zhi Guang GE Jia Pu SHAN Guang Liang | 2014 | Biomedical and Environmental Sciences2014，27，5： | 17 |
| 15 | The discovery of the oldest rocks in the Kuluketage area and its geological implications显示文摘The basement rocks in the Kuluketage area are composed predominately of tonalite-trondhjemite-granodiorite rocks, and occured mainly in Xinger and Korla. U-Pb dating of TTG gneiss near Korla yielded a late Neoarchean weighted mean 207Pb/206Pb age of 2.65 Ga, which is the oldest published age for the TTG rocks in the Kuluketage area and thus suggests that Archean terrane in the area was formed in the late Neoarchean. The Korla gneiss is much younger than the TTG rocks in the northern Altyn Tagh, eastern Tarim Craton, indicating that the oldest terrane of the Tarim Craton was exposed probably in the northern Altyn Tagh. Until late Neoarchean, the Tarim continent extends to the Kuluketage area and finally had generated a relatively large uniform Archean basement within the craton. Zircon Hf isotopic analyses of the TTG gneiss give low εHf(t) values (-5 to 1) with Paleoarchean to Mesoarchean two-stage model ages (TDM2) between 3.0 and 3.3 Ga, suggesting that the basement rocks in the northern Tarim Craton were derived dominately from partial melting of Paleoarchean to Mesoarchean juvenile crustal material. The Hf model ages, therefore, indicate that no continent crust older than 3.3 Ga existed in the Kuluketage area. | LONG XiaoPing YUAN Chao SUN Min XIAO WenJiao ZHAO GuoChun ZHOU KeFa WANG YuJing HU AiQin | 2011 | Science China Earth Sciences2011，54，3： | 16 |
| 16 | Long noncoding RNA RP4 functions as a competing endogenous RNA through miR-7-5p sponge activity in colorectal cancer显示文摘AIM To investigate the role of long noncoding RNA(lnc RNA) RP4 in colorectal cancer.METHODS Lentivirus-mediated lnc RNA RP4 overexpression and knockdown were performed in the colorectal cancer cell line SW480. Cell proliferation, tumor growth, and early apoptosis were evaluated by a cell counting kit-8 assay, an in vivo xenograft tumor model, and annexin V/propidium iodide staining, respectively. Analysis of the lnc RNA RP4 mechanism involved assessment of the association of its expression with mi R-7-5 p and the SH3 GLB1 gene. Western blot analysis was also performed to assess the effect of lnc RNA RP4 on the autophagy-mediated cell death pathway and phosphatidylinositol-3-kinase(PI3 K)/Akt signaling.RESULTS Cell proliferation, tumor growth, and early apoptosis in SW480 cells were negatively regulated by lnc RNA RP4. Functional experiments indicated that lnc RNA RP4 directly upregulated SH3 GLB1 expression by acting as a competing endogenous RNA(ce RNA) for mi R-7-5 p. This interaction led to activation of the autophagy-mediated cell death pathway and de-repression of PI3 K and Akt phosphorylation in colorectal cancer cells in vivo.CONCLUSION Our results demonstrated that lnc RNA RP4 is a ce RNA that plays an important role in the pathogenesis of colorectal cancer, and could be a potential therapeutic target for colorectal cancer treatment. | Mu-Lin Liu Qiao Zhang Xiao Yuan Long Jin Li-Li Wang Tao-Tao Fang Wen-Bin Wang | 2018 | World Journal of Gastroenterology2018，24，9： | 16 |
| 17 | Gefitinib plus Fuzheng Kang'ai Formula(扶正抗癌方) in Patients with Advanced Non-Small Cell Lung Cancer with Epidermal Growth Factor Receptor Mutation:A Randomized Controlled Trial显示文摘Objective: To evaluate the effect of Fuzheng Kang'ai Formula(扶正抗癌方, FZKA) plus gefitinib in patients with advanced non-small cell lung cancer with epidermal growth factor receptor(EGFR) mutations. Methods: A randomized controlled trial was conducted from 2009 to 2012 in South China. Seventy chemotherapynaive patients diagnosed with stage ⅢB/Ⅳ non-small cell lung cancer with EGFR mutations were randomly assigned to GF group [gefitinib(250 mg/day orally) plus FZKA(250 m L, twice per day, orally); 35 cases] or G group(gefitinib 250 mg/day orally; 35 cases) according to the random number table and received treatment until progression of the disease, or development of unacceptable toxicities. The primary endpoint [progression-free survival(PFS)] and secondary endpoints [median survival time(MST), objective response rate(ORR), disease control rate(DCR) and safety] were observed. Results: No patient was excluded after randomization. GF group had significantly longer PFS and MST compared with the G group, with median PFS of 12.5 months(95% CI 3.30–21.69) vs. 8.4 months(95% CI 6.30–10.50; log-rank P<0.01), MST of 21.5 months(95% CI 17.28–25.73) vs. 18.3 months(95% CI 17.97–18.63; log-rank P<0.01). ORR and DCR in GF group and G group were 65.7% vs. 57.1%, 94.3% vs. 80.0%, respectively(P>0.05). The most common toxic effects in the GF group and G group were rash or acne(42.8% vs. 57.1%, P>0.05), diarrhea(11.5% vs. 31.4%, P<0.05), and stomatitis(2.9% vs. 8.7%, P>0.05). Conclusion: Patients with advanced non-small cell lung cancer selected by EGFR mutations have longer PFS, MST with less toxicity treated with gefitinib plus FZKA than gefitinib alone. | YANG Xiao-bing CHAI Xiao-shu WU Wan-yin LONG Shun-qin DENG Hong PAN Zong-qi HE Wen-feng ZHOU Yu-shu LIAO Gui-ya XIAO Shu-jing | 2018 | Chinese Journal of Integrative Medicine2018，24，10： | 15 |
| 18 | Geologic characteristics of the Chang'E-3 exploration region显示文摘We present topographic,geomorphologic and compositional characteristics of a 1°×1°(~660 km2)region centered near the landing site of Chang’E-3 using the highest spatial resolution data available.We analyze the topography and slope using Digital Terrain Model(DTM)generated from Terrain Camera(TC)images.The exploration region is overall relatively flat and the elevation difference is less than 300 m,and the slopes of 80%area are less than 5°.Impact craters in the exploration region are classified into four types based on their degradation states.We investigate the wrinkle ridges visible in the exploration region in detail using TC and Lunar Reconnaissance Orbiter(LRO)Narrow Angle Camera(NAC)images.We calculate FeO and TiO2 abundances using Multispectral Imager(MI)data,and confirm two basaltic units:the northern part belongs to Imbrian low-Ti/very-low-Ti mare basalts,and the southern part is Eratosthenian low-Ti/high-Ti mare basalts.Finally,we produce a geological map and propose the geologic evolution of the exploration region.We also suggest several rover traverses to explore interesting targets and maximize the potential scientific output. | ZHAO JianNan HUANG Jun QIAO Le XIAO ZhiYong HUANG Qian WANG Jiang HE Qi XIAO Long | 2014 | Science China(Physics,Mechanics & Astronomy)2014，57，3： | 14 |
| 19 | Effect of electrically stimulating acupoint, Zusanli(ST 36), on patient’s recovery after laparoscopic colorectal cancer resection: a randomized controlled trial显示文摘OBJECTIVE:To investigate the effect of transcutaneous electrical acupoint stimulation (TEAS) on enhanced recovery after surgery (ERAS) in laparoscopic colorectal cancer resection and its clinical significance.METHODS:Sixty-four patients undergoing laparoscopic colorectal resection were randomly divided into two groups,the control group (group A) and the TEAS group (group B).Patients in the TEAS group received electroacupuncture stimulation of bilateral Zusanli (ST 36) at 30 min before anesthesia to the end of surgery.The patients in the control group were not given the stimulation.Perioperative anesthesia management of the two groups were performed according to the ERAS guidelines,and postoperative patient-controlled intravenous analgesia (PCIA) was used.The amount of remifentanil used in the two groups was observed and recorded,and the visual analogue scale (VAS) of the 4,12,24 and 48 h after surgery in the two groups was recorded.Moreover,postoperative anal exhaust time,postoperative feeding time,postoperative first ambulation time and postoperative hospital stay length were compared between the two groups.RESULTS:Compared with group A,the VAS score of group B decreased significantly at 48 h after operation (P < 0.05).The postoperative anal exhaust time in group B was significantly shorter than that of group A (P < 0.05).There was no significant difference between the two groups with regards to remifentanil consumption,postoperative feeding time,postoperative first ambulation time and postoperative hospital stay (all P > 0.05).CONCLUSION:TEAS can promote the recovery of postoperative gastrointestinal function and reduce the pain intensity 48 h after surgery,thus satisfying the need of early postoperative analgesia. | Huang Wei Yu Tingyu Long Wenfei Xiao Jianbin Zhao Gaofeng | 2019 | Journal of Traditional Chinese Medicine2019，39，3： | 14 |
| 20 | Experimental quantum secure direct communication with single photons显示文摘Quantum secure direct communication is an important mode of quantum communication in which secret messages are securely communicated directly over a quantum channel.Quantum secure direct communication is also a basic cryptographic primitive for constructing other quantum communication tasks,such as quantum authentication and quantum dialog.Here,we report the first experimental demonstration of quantum secure direct communication based on the DL04 protocol and equipped with single-photon frequency coding that explicitly demonstrated block transmission.In our experiment,we provided 16 different frequency channels,equivalent to a nibble of four-bit binary numbers for direct information transmission.The experiment firmly demonstrated the feasibility of quantum secure direct communication in the presence of noise and loss. | Jian-Yong Hu Bo Yu Ming-Yong Jing Lian-Tuan Xiao Suo-Tang Jia Guo-Qing Qin Gui-Lu Long | 2016 | Light(Science & Applications)2016，5，1： | 14 |
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