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| 1 | CKIP-1 regulates macrophage proliferation by inhibiting TRAF6-mediated Akt activation显示文摘巨噬细胞在开发,动态平衡,织物修理和免疫起枢轴的作用。巨噬细胞增长被刺激殖民地的因素(M-CSF ) 导致了 Akt 发信号的巨噬细胞支持;然而,这个过程怎么被终止,仍然保持不清楚。这里,我们作为巨噬细胞增长的一个新奇禁止者识别酷蛋白 kinase 2-interacting protein-1 (CKIP-1 ) 。在放松巨噬细胞, CKIP-1 是在由组成地活跃的 GSK3β 的丝氨酸 342 点的 phosphorylated;, Akt 的下游的目标。这 phosphorylation 触发 CKIP-1 的 polyubiquitination 和 proteasomal 降级。在 M-CSF 刺激之上, Akt 被 CSF-1R-PI3K 激活然后使 GSK3β 失去活性;,导致 CKIP-1 和 β 的稳定; -catenin 蛋白质。β -catenin 包括 cyclin D 和 c-Myc 支持增长基因的表示。CKIP-1 与 TRAF6,为连接 K63 的 ubiquitination 要求的 ubiquitin ligase 和 Akt 的血浆膜招募交往,并且终止调停 TRAF6 的 Akt 激活。由这个工具, CKIP-1 在 M-CSF 刺激以后在迟了的阶段明确地禁止巨噬细胞增长。而且, CKIP-1 缺乏在老鼠自发地开发的 vitro 和 CKIP-1 −/− 导致增加的增长和巨噬细胞的减少的 apoptosis 巨噬细胞主导的脾大和 myeloproliferation。一起,这些数据证明 CKIP-1 由禁止调停 TRAF6 的 Akt 激活在巨噬细胞动态平衡的规定起一个关键作用。 | Luo Zhang Yiwu Wang Fengjun Xiao Shaoxia Wang Guichun Xing Yang Li Xiushan Yin Kefeng Lu Rongfei Wei Jiao Fan Yuhan Chen Tao Li Ping Xie Lin Yuan Lei Song Lanzhi Ma Lujing Ding Fuchu He Lingqiang Zhang | 2014 | Cell Research2014，24，6： | 7 |
| 2 | Sand particle lift-off velocity measurements and numerical simulation of mass flux distributions in a wind tunnel显示文摘Lift-off velocity of saltating sand particles in wind-blown sand located at 1.0 mm above the sand bed surface was measured using a phase Doppler particle analyzer in a wind tunnel. The results show that the probability distribution of lift-off velocity can be expressed as a lognormal function, while that of lift-off angle follows an exponential function. The probability distribution of lift-off angle conditioned for each lift-off velocity also follows an exponential function, with a slope that becomes steeper with increasing lift-off velocity. This implies that the probability distribution of lift-off velocity is strongly dependent on the lift-off angle. However, these lift-off parameters are generally treated as an independent joint probability distribution in the literature. Numerical simulations were carried out to investigate the effects of conditional versus independent joint probability distributions on the vertical sand mass flux distribution. The simulation results derived from the conditional joint probability distribution agree much better with experimental data than those from the independent ones. Thus, it is better to describe the lift-off velocity of saltating sand particles using the conditional joint probability distribution. These results improve our understanding of saltation processes in wind-blown sand. | XIAO Fengjun DONG Zhibao GUO Liejin WANG Yueshe LI Debiao | 2017 | Journal of Arid Land2017，9，3： | 3 |
| 3 | SPACEBORNE SAR REAL-TIME ECHO SIMULATION PLATFORM BASED ON VPX显示文摘To perform the ground test of a spaceborne Synthetic Aperture Radar(SAR) system, an echo simulator with the characteristics of multimode, multi-assemblage, and real time is proposed in this paper. A hardware platform of the real-time echo simulator based on the VPX bus is designed. With this platform, real-time multi-point echo generation and scenario targets echo generation can be achieved by the real-time signal processing in Field Programmable Gate Array(FPGA), utilizing the parameters calculated by the industry computers. Furthermore, this platform can output different signals if it is expanded to multi-channels, making it possible for the assignment of echo generation and test in different spaceborne SAR modes. The test results with the actual SAR system show that this platform can satisfy the system requirements and is now used in practice. | Ni Chao Hu Xiao Zhang Zhimin Zhao Fengjun | 2014 | Journal of Electronics(China)2014，31，3： | 2 |
| 4 | Transforming growth factor β3 attenuates the development of radiation-induced pulmonary fibrosis in mice by decreasing fibrocyte recruitment and regulating IFN-γ/IL-4 balance显示文摘 | Long Xu Shanshan Xiong Renfeng Guo Zhihua Yang Qianjun Wang Fengjun Xiao Haibao Wang Xiujie Pan Maoxiang Zhu | 2014 | Immunology Letters2014，，1： | 1 |
| 5 | Fetch effect on the developmental process of aeolian sand transport in a wind tunnel显示文摘As the sand mass flux increases from zero at the leading edge of a saltating surface to the equilibrium mass flux at the critical fetch length,the wind flow is modified and then the relative contribution of aerodynamic and bombardment entrainment is changed.In the end the velocity,trajectory and mass flux profile will vary simultaneously.But how the transportation of different sand size groups varies with fetch distance is still unclear.Wind tunnel experiments were conducted to investigate the fetch effect on mass flux and its distribution with height of the total sand and each size group in transportation.The mass flux was measured at six fetch length locations(0.5,1.2,1.9,2.6,3.4 and 4.1 m)and at three free-stream wind velocities(8.8,12.2 and 14.5 m/s).The results reveal that the total mass flux and the mass flux of each size group with height can be expressed by q=aexp(–bh),where q is the sand mass flux at height h,and a and b are regression coefficients.The coefficient b represents the relative decay rate.Both the relative decay rates of total mass flux and each size group are independent of fetch length after a quick decay over a short fetch.This is much shorter than that of mass flux.The equilibrium of the relative decay rate cannot be regarded as an equilibrium mass flux profile for aeolian sand transport.The mass fluxes of 176.0,209.3 and 148.0μm size groups increase more quickly than that of other size groups,which indicates strong size-selection of grains exists along the fetch length.The maximal size group in mass flux(176.0μm)is smaller than the maximal size group of the bed grains(209.3μm).The relative contribution of each size group to the total mass flux is not monotonically decreasing with grain size due to the lift-off of some small grains being reduced due to the protection by large grains.The results indicate that there are complex interactions among different size groups in the developmental process of aeolian sand transport and more attention should be focused on the fetch effect because it has different influences on the total mass flux,the mass flux profile and its relative decay rate. | CHEN Zongyan XIAO Fengjun DONG Zhibao | 2020 | Journal of Arid Land2020，12，3： | 1 |
| 6 | A field investigation of wind erosion in the farming–pastoral ecotone of northern China using a portable wind tunnel: a case study in Yanchi County显示文摘The farming–pastoral ecotone in northern China is an extremely fragile ecological zone where wind erosion of cropland and rangeland is easy to occur. In this study, using a portable wind tunnel as a wind simulator, we conducted field simulated wind erosion experiments combined with laboratory analysis to investigate wind erosion of soils in trampled rangeland, non-tilled cropland and tilled cropland in Yanchi County, China. The results showed that compared with rangeland, the cropland had a higher soil water holding capacity and lower soil bulk density. The wind erosion rate of trampled rangeland was much higher than those of non-tilled cropland and tilled cropland. For cropland, the wind erosion rate of the soil after tilling was surprisingly less than that of the soil before tilling. With increasing of wind speed, the volume mean diameter of the eroded sediment collected by the trough in the wind tunnel generally increased while the clay and silt content decreased for all soils. The temporal variation in wind erosion of the trampled rangeland indicated that particle entrainment and dust emission decreased exponentially with erosion time through the successive wind erosion events due to the exhaustion of erodible particles. | nan ling dong zhibao xiao weiqiang li chao xiao nan song shaopeng xiao fengjun du lingtong | 2018 | Journal of Arid Land2018，10，1： | 0 |
| 7 | Activated carbon fiber mediates efficient activation of peroxymonosulfate systems:Modulation of manganese oxides and cycling of manganese species显示文摘Manganese oxides show a strong catalytic activity in the peroxymonosulfate(PMS)advanced oxidation process but have poor chemical stability and a propensity to cause the aggregation of nanoparticles.Here,a novel composite material(abbreviated as MnO_(x)@ACF)was synthesized,characterized,and applied.Activated carbon fiber(ACF)was selected as a carrier,which modulated the composition of manganese oxides.The results showed that MnO_(x)@ACF had a strong adsorption ability and successfully activated PMS to degrade tetracycline hydrochloride(TCH),with a removal eficiency of 89.0%in 30 min.Influencing factors such as pH and coexisting ion species were investigated,and a five-cycle test was conducted.Singlet oxygen(^(1)O_(2))was predominated in the MnO_(x)@ACF/PMS system.A possible explanatory pathway of TCH was proposed based on the results of the high performance liquid chromatography-mass spectrometry.It was concluded that this study provides a novel insight into the activation of PMS for the degradation of organic matter by carbon-loaded multivalent manganese oxides. | Lixi Xiao Yuwei Deng Huo Zhou Fengjun Lu Chong Ke Yuxuan Ye Xuanyuan Pei Dongsheng Xia Fei Pan | 2023 | Chinese Chemical Letters2023，34，12： | 0 |
| 8 | The Interannual and Interdecadal Variations of Tropical Cyclone Affecting Shandong Province显示文摘Based on tropical cyclone yearbook data from 1949 to 2006,climate characteristics,such as interdecadal variation,period of tropical cyclone frequency,rainstorm and strong wind,intensity characteristics,were analyzed. Main results were as follows: tropical cyclone affecting Shandong Province was mainly from the last ten-day of July to the last ten-day of August,and its interdecadal variation was obvious. The marked periodic variation of every 2. 4 and 5 years was found according to power spectrum analysis. It showed obvious weakening tendency about tropical cyclone's intensity by using Kendall test. It also showed that August was the strongest month among a year for rainstorm frequency and intensity,and flood disaster was more easily to occur during this month. It was distinct for frequency's interdecadal variation of tropical cyclone causing rainstorm and strong wind. Marked period was existed about annual average precipitation and strong wind. At the same time,the cause of the variation was discussed. | Gao Xiaomei Wang Lingjun Ma Jinsong Yan Fengjun Xu Guihua Han Xiao Su Lili | 2014 | Meteorological and Environmental Research2014，5，12： | 0 |
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