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64篇 您的检索式:作者名="Wilson PS"
    题名 作者 年代 出处 被引量
1胆固醇酯转移蛋白基因的蛋白质截断型变异体与冠状动脉性心脏病风险的关系显示文摘随机对照试验结果表明,抑制胆固醇酯转运蛋白(cholesteryl ester transfer protein,CETP)的疗法并不能降低冠状动脉性心脏病(coronary heart disease,CHD)的发生风险。研究失败的可能原因包括靶目标无效、靶目标外小分子的不良反应和随机对照设计因素影响等。在编码药物靶点的基因中具有天然存在的遗传变异,以此为基础,人类研究可以深入了解针对基因产物的治疗的潜在功效和安全性。Nomura A Won HH Khera AV Takeuchi F Ito K McCarthy S Emdin CA Klarin D Natarajan P Zekavat SM Gupta N Peloso GM Borecki IB Teslovich TM Asselta R Duga S Merlini PA Correa A Kessler T Wilson JG Bown MJ Hall AS Braund PS Carey DJ Murray MF Kirchner HL Leader JB Lavage DR Manus JN Hartze DN Samani NJ Schunkert H Marrugat J Elosua R McPherson R Farrall M Watkins H Juang JJ Hsiung CA Lin SY Wang JS Tada H Kawashiri MA Inazu A Yamagishi M Katsuya T Nakashima E Nakatochi M Yamamoto K Yokota M Momozawa Y Rotter JI Lander ES Rader DJ Danesh J Ardissino D Gabriel S Willer CJ Abecasis GR Saleheen D Kubo M Kato N Ida Chen YD Dewey FE Kathiresan S 刘莉 叶鹏 2017中华高血压杂志2017,25,9:2
2The outer bilayer of the adult sehistosome tegument surface has a low turnover rate in vitro and in vivo显示文摘Saunders N Wilson RA Coulson PS 1987Mol Biochem Parasitol1987,25,2:1
3GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides显示文摘Phiel CJ Wilson CA Lee VM Klein PS 2003Nature2003,423,6938:1
4Immune responses to the radiation-attenuated schistosome vaccine:what can we learn from knock-out mice?显示文摘Wilson RA Coulson PS Mountford AP 1999Immunol Lett1999,65,12:1
5The T deflection of the electrocardiogram显示文摘 Macleod AG Barker PS 1931Trans Assoc Am Physicians1931,46,:1
6Role of 'buttoned' double-disc device in the management of artrial septal defects显示文摘 Wilson AD Levy JM 1992Am Heart J1992,123,1:1
7Monoclonal antibody to IFN-gamma modifies pulmonary inflammatory responses and abrogates immunity to Schistosoma mansoni in mice vaccinated with attenuated cercariae显示文摘Smythies LE Coulson PS Wilson RA 1992J Immunol1992,149,:1
8Impaired immunity and altered pulmonary responses in mice with a disrupted interferon-gamma receptor gene exposed to the irradiated Schistosoma mansoni vaccine显示文摘Wilson RA Coulson PS Betts C 1996Immunology1996,87,:1
9GSK-3alpha regulates production of Alzheimer's disease amyloid-beta peptides显示文摘Phiel CJ Wilson CA Lee VM Klein PS 2003Nature2003,423,6938:1
10The mechanism of auricular paroxysmal tachycardia显示文摘Barker PS Wilson FN Johnston FD 1943American Heart Journal1943,26,4:1
11Immunity to Schistosoma mansoni in mice vaccinated with irradiated ccreariae: cytokine interactions in the pulmonary protective response显示文摘Smythies LE Coulson PS Wilson RA 1993Ann Trop Med Parasitol1993,87,6:1
12IL-4 receptor signaling is required for mannose receptor expression by macrophages recruited to granulomata but not resident cells in mice infected with Schistosoma mansoni显示文摘Linehan SA Coulson PS Wilson RA 2003Lab Invest2003,83,8:1
13The mechanism of au- ricular paroxysmal tachycardia 显示文摘Barker PS Wilson FN Johnston FD 1943American Heart Journal1943,26,:1
14White matter mapping using diffusion tensor MRI显示文摘 Morgan PS Wilson M 2002Magn Reson Med2002,47,:1
15Infections, immunity and ath- erosclerosis~associations of antibodies to Chlamydia pneumoni ae,hecicobacerr pylori and cytomegalovirus with immune reac- tions to heat-sheck protein 60 and carotid or femoral atheroscle- rosis显示文摘Magr M Jacob A Wilson PS 2000Circulation2000,102,:1
16Characterization, cloning and immunogenicity of antigens released by lung-stage larvae of Schistosoma mansoni 显示文摘Harrop R Coulson PS Wilson RA 1999Parasitology1999,118,6:1
17Characterization, cloning and immunogenicity of antigens released by lung-stage larvae of Schistosoma mansoni显示文摘Harrop R Coulson PS Wilson RA 1999Parasitology1999,118,6:1
18Lung-phase immunity to Schistosornes: a new perspective on an old problem? 显示文摘Wilson RA Coulson PS 1989Parasitol Today1989,5,9:1
19Pyramidal tract mapping by diffusion tensor magnetic resonance imaging in multiple sclerosis: improving correlations with disability显示文摘Wilson M Trench CR Morgan PS 2003J Neurol Neurosurg Psychiatry2003,74,:1
20IL-4 receptor signal- ing is required for mannose receptor expression by macrophages re- cruited to granulomata but not resident ceils in mice infected with Schistosoma mansoni显示文摘Linehan SA Coulson PS Wilson RA 2003Lab Invest2003,83,8:1
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