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| 1 | Comparison of nonhuman primates identified the suitable model for COVID-19显示文摘Identification of a suitable nonhuman primate(NHP)model of COVID-19 remains challenging.Here,we characterized severe acute respiratory syndrome coronavirus 2(SARS-CoV-2)infection in three NHP species:Old World monkeys Macaca mulatta(M.mulatta)and Macaca fascicularis(M.fascicularis)and New World monkey Callithrix jacchus(C.jacchus).Infected M.mulatta and M.fascicularis showed abnormal chest radiographs,an increased body temperature and a decreased body weight.Viral genomes were detected in swab and blood samples from all animals.Viral load was detected in the pulmonary tissues of M.mulatta and M.fascicularis but not C.jacchus.Furthermore,among the three animal species,M.mulatta showed the strongest response to SARS-CoV-2,including increased inflammatory cytokine expression and pathological changes in the pulmonary tissues.Collectively,these data revealed the different susceptibilities of Old World and New World monkeys to SARS-CoV-2 and identified M.mulatta as the most suitable for modeling COVID-19. | Shuaiyao Lu Yuan Zhao Wenhai Yu Yun Yang Jiahong Gao Junbin Wang Dexuan Kuang Mengli Yang Jing Yang Chunxia Ma Jingwen Xu Xingli Qian Haiyan Li Siwen Zhao Jingmei Li Haixuan Wang Haiting Long Jingxian Zhou Fangyu Luo Kaiyun Ding Daoju Wu Yong Zhang Yinliang Dong Yuqin Liu Yinqiu Zheng Xiaochen Lin Li Jiao Huanying Zheng Qing Dai Qiangming Sun Yunzhang Hu Changwen Ke Hongqi Liu Xiaozhong Peng | 2020 | Signal Transduction and Targeted Therapy2020,5,1: | 5 |
| 2 | Study of solvent casting/particulate leaching technique membranes in pervaporation for dehydration of caprolactam显示文摘 | Wenhai Lin Qin Li Tianrong Zhu | 2012 | Journal of Industrial and Engineering Chemistry2012,,3: | 1 |
| 3 | New chitosan/konjac glucomannan blending membrane for application in pervaporation dehydration of caprolactam solution显示文摘 | LIN Wenhai LI Qin ZHU Tianrong | 2012 | Journal of Industrial and Engineering Chemistry2012,18,3: | 1 |
| 4 | 显示文摘 | Lin Jian Huang Wenhai Lei Shuhua | 2008 | Journal of Ceramic Processing Research2008,4,: | 1 |
| 5 | Effects of strontium in modified biomaterials显示文摘 | Weibin Zhang Yuhui Shen Haobo Pan Kaili Lin Xiaoguo Liu Brian W. Darvell William W. Lu Jiang Chang Lianfu Deng Deping Wang Wenhai Huang | 2010 | Acta Biomaterialia2010,,2: | 1 |
| 6 | Asian,regional,and national burdens of respiratory tract cancers and associated risk factors from 1990 to 2019:A systematic analysis for the global burden of disease study 2019显示文摘Background:Respiratory cancer is the leading cause of cancer-related deaths worldwide,but its statistics vary between the East and West.This study aimed to estimate the burdens of tracheal,bronchus,and lung(TBL)cancer and larynx cancer and their attributable risks from 1990 to 2019 in Asia,and at regional and national levels.Methods:This research evaluated the incidence,mortality,years lived with disability,years of life lost,and disability-adjusted life years(DALYs)for respiratory tract cancers using the Global Burden of Diseases,Injuries,and Risk Factors Study(GBD)2019 database.Age-standardized rates were calculated for TBL cancer from 1990 to 2019,adjusted for smoking and socio-demographic index(SDI).Deaths from TBL cancer and larynx cancer attributable to each risk factor were estimated for 33 Asian countries.Results:The age-standardized incidence and death rates for TBL cancer in Asia declined from 2010 to 2019,while the incidence rate of larynx cancer increased.Smoking was the leading specific risk factor for deaths from both TBL and larynx cancers.The burden of TBL cancer in Asian countries was influenced by SDI and smoking,particularly among males in Central Asia.Deaths,DALYs,and incidences of larynx cancer in East Asia had not changed significantly over the past 30 years,but showed slight downward trends in males and both sexes combined,and an upward trend in females in recent years.Conclusions:The past decade saw increases in numbers of incident cases and deaths from TBL cancer and larynx cancer in Asia.SDI and smoking were the main factors influencing the disease burden of TBL cancer in Asian countries.This study highlights the need for tailored cancer control programs to address the burden of respiratory tract cancers in different Asian countries. | Ran Zhong Xiuyu Cai Jianfu Li Peiling Chen Runchen Wang Xinting Li Feng Li Shan Xiong Caichen Li Huiting Wang Yang Xiang Shuting Zhan Ziwen Yu Haixuan Wang Chunyan Li Lixuan Lin Wenhai Fu Xin Zheng Shen Zhao Kang Zhang Jianxing He | 2023 | Chinese Medical Journal Pulmonary and Critical Care Medicine2023,1,4: | 1 |
| 7 | Size characteristics of fungus allergens in subtropical climate显示文摘 | LIN Wenhai LI C S | 1996 | Aerosol Science and Technology1996,25,2: | 1 |
| 8 | New chitosan/Konjac glucomannan blending membrane for application in pervaporation dehydration of caprolactam solution 显示文摘 | Lin Wenhai Li Qin Zhu Tianrong | 2012 | Journal of Industrial and Engineering Chemistry2012,18,3: | 1 |
| 9 | Analyses on Numerical Simulation in Several Paving Types of Floor Heating显示文摘 | Qiu Lin Wang Wenhai You Minyu | 2003 | The 4^th Intenational Symposium on HVAC Beijing China2003,10,: | 1 |
| 10 | New chitosan/konjac glucomannan blending membrane for application in pervaporation dehydration of caprolactam solution显示文摘 | LIN Wenhai LI Qin ZHU Tianrong | 2012 | Journal of Industrial and Engineering Chemistry2012,18,: | 1 |
| 11 | PEGylated BODIPY assembling fluorescent nanoparticles for photodynamic therapy显示文摘Two amphiphilic macromolecules were synthesized from polyethylene glycol monomethylether(PEG)and borondipyrrolmethene(BODIPY) via one-pot multicomponent Passerini reaction,and they could self-assemble into stable nanoparticles(NPs) in aqueous media.The optical properties,including fluorescence resonance energy transfer(FRET) were studied in detail.The obtained NPs possess good cytocompatibility,and could be used for living cell imaging and effective photodynamic therapy(PDT).These results shed light on one-pot synthesis of PEGylated fluorescent nanoparticles via multicomponent reaction for biomedical application. | Yu Zhu Wenhai Lin Wei Zhang Yuqin Feng Zhineng Wu Li Chen Zhigang Xie | 2017 | Chinese Chemical Letters2017,28,9: | 1 |
| 12 | Preparation of AgCl Nano-Crystal Embedded Tellurite Nonlinear Optical Glasses under Electric Field Accompanied Heat Treatment显示文摘The quantum effect of nano-crystals is an important factor to improve nonlinear optical performance of nano- crystal embedded glasses,while controlling the size distribution and content of nano-crystals in the glass accurately is a key to obtain good quality.The auxiliary direct current electric field,accompanied with heat treatment,was applied on AgCl containing niobic tellurite glass sheet.The nucleation and crystallization of the glass were well controlled under auxiliary electric field.It was found that the average size of AgCl nano-crystal particles in the glass is smaller than that under single heat treatment,and the content of nano- crystals is higher.Therefore the third-order nonlinear optical performance of the gJass was increased a lot. The local-area distributed AgCl nano-crystal particles can also be embedded into a glass sheet by using locally applied electric field. | Jian LIN Wenhai HUANG Bofang LI Chong JIN Changcheng LIU Shuhua LEI Zhenrong SUN | 2008 | Journal of Materials Science & Technology2008,24,6: | 0 |