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| 1 | The development and function of follicular helper T cells in immune responses显示文摘小囊的助手 T 房间(Tfh ) 作为提供帮助让 B 房间增殖并且在幼芽的中心经历抗体亲密关系成熟的一个系被提交了。证据支持了那个 Tfh 子集开发象另外的系一样,依赖于一个特别 transcriptional 节目被开始的微型环境。它为 Tfh 房间的开发和函数作为主人管理者被看了那 Bcl-6 和 IL-21 行为。Tfh dysregulation 涉及自体免疫的病理的发展,例如全身的豺狼座 erythematosus,风湿性关节炎和另外的自体免疫的疾病。现在的评论在在他们的开发和函数的 Tfh 房间和焦点的域里加亮最近的进展。 | Maogen Chen Zhiyong Guo Weiqiang Ju Bernhard Ryffel Xiaoshun He Song Guo Zheng | 2012 | Cellular & Molecular Immunology2012，9，5： | 18 |
| 2 | Global Dynamic Molecular Profiling of Stomatal Lineage Cell Development by Single-Cell RNA Sequencing显示文摘The regulation of stomatal lineage cell development has been extensively investigated.However,a comprehensive characterization of this biological process based on single-cell transcriptome analysis has not yet been reported.In this study,we performed RNA sequencing on 12844 individual cells from the cotyledons of 5-day-old Arabidopsis seedlings.We identified 11 cell clusters corresponding mostly to cells at specific stomatal developmental stages using a series of marker genes.Comparative analysis of genes with the highest variable expression among these cell clusters revealed transcriptional networks that regulate development from meristemoid mother cells to guard mother cells.Examination of the developmental dynamics of marker genes via pseudo-time analysis revealed potential interactions between these genes.Collectively,our study opens the door for understanding how the identified novel marker genes participate in the regulation of stomatal lineage cell development. | Zhixin Liu Yaping Zhou Jinggong Guo Jiaoai Li Zixia Tian Zhinan Zhu Jiajing Wang Rui Wu Bo Zhang Yongjian Hu Yijing Sun Yan Shangguan Weiqiang Li Tao Li Yunhe Hu Chenxi Guo Jean-David Rochaix Yuchen Miao Xuwu Sun | 2020 | Molecular Plant2020，13，8： | 11 |
| 3 | Mechanical Properties and Microstructure of 6082-T6 Aluminum Alloy Joints by Self-support Friction Stir Welding显示文摘The majority of this research has concentrated on developing the self-support friction stir welding(SSFSW) tool which consists of a big concave upper shoulder and a small convex lower shoulder, and procedures for making reliable welds in aluminum hollow extrusion. The 5-mm-thick 6082-T6 aluminum alloy was self-support friction stir welded at a constant tool rotation speed of 800 r/min. The effect of welding speed on microstructure and mechanical properties was investigated. The results of transverse tensile test indicated that the tensile strength of joints increased and the elongation decreased with increasing welding speed. The whole values of microhardness of SSFSW joints increased with increasing welding speed from 10 to 200 mm/min. The defectfree joints were obtained at lower welding speeds and the tensile fracture was located at the heat-affected zone(HAZ) adjacent to the thermo-mechanically affected zone(TMAZ) on the advancing side. The investigation of the flow pattern of the softened metal around the SSFSW tool revealed that the flow pattern of the softened metal was driven by two shoulders and the stir pin. The failure of specimens in tension presented the ductile fracture mode. | Long Wan Yongxian Huang Weiqiang Guo Shixiong Lv Jicai Feng | 2014 | Journal of Materials Science & Technology2014，30，12： | 10 |
| 4 | Nonintubated thoracoscopic lobectomy plus lymph node dissection following segmentectomy for central type pulmonary masses显示文摘IntroductionLung cancer is the most common cancer worldwide.In the United States,it causes more cancer-related deaths than the next four causes(breast cancer,prostate cancer,colon cancer,and pancreatic cancer)of cancer-related mortality combined(1).About 30% of people have already | Wenlong Shao Wei Wang Weiqiang Yin Zhihua Guo Guilin Peng Ying Chen Jianxing He | 2013 | Chinese Journal of Cancer Research2013，25，1： | 7 |
| 5 | Controlled synthesis of high-quality W-Y2O3 composite powder precursor by ascertaining the synthesis mechanism behind the wet chemical method显示文摘As an emerging preparation technology,wet chemical method has been employed widely to produce lots of alloy materials such as W and Mo based alloys,owing to its unique technical advantages.Ascertaining the synthesis mechanism behind wet chemical method is indispensable for controlled synthesis of highquality W-Y2 O3 composite powder precursor.The co-deposition mechanism of yttrium and tungsten component behind the wet chemical method of preparing yttrium-doped tungsten composite nanopowder was investigated systematically in this work.A series of co-deposited composite powders fabricated under different acidity conditions were used as research targets for investigating the effect of surface composition and structure on co-deposition efficiency.It was found that white tungstic acid has more W-OH bonds and much higher co-deposition efficiency with Y^3+ions than yellow tungstic acid.It is illustrated that the coordination reaction between W-OH bonds on tungstic acid particles and Y^3+ions brings the co-deposition of yttrium and tungsten component into being.Through displacing H^+ions in W-OH bonds,Y^3+ions can be adsorbed on the surface of or incorporated into tungstic acid particles in form of ligand.Consequently,to control and regulate Y2 O3 content in powder precursor accurately,H^+ion concentration in wet chemical reaction should be in range of 0.55-2.82 mol L^-1 to obtain white tungstic acid.Besides,H^+ion concentration also has prominent effect on the grain size and morphology of reduced powder precursor.The optimal value should be around 1.58 mol L^-1,which can lead to minimum W grain size(about 17 nm) without bimodal structure.The chemical mechanism proposed in this work could produce great sense to preparation of high-quality precursor for sintering high-performance Y2 O3 dispersion strengthened W based alloys.Our work may also shed light on the approach to exploit analogous synthesis mechanism in other alloy systems. | Zhi Dong Nan Liu Weiqiang Hu Zongqing Ma Chong Li Chenxi Liu Qianying Guo Yongchang Liu | 2020 | Journal of Materials Science & Technology2020，36，1： | 7 |
| 6 | Glossy15 Plays an Important Role in the Divergence of the Vegetative Transition between Maize and Its Progenitor, Teosinte显示文摘 | Dingyi Xu Xufeng Wang Cheng Huang Guanghui Xu Yameng Liang Qiuyue Chen Chenglong Wang Dan Li Jinge Tian Lishuan Wu Yaoyao Wu Li Guo Xuehan Wang Weihao Wu Weiqiang Zhang Xiaohong Yang Feng Tian | 2017 | Molecular Plant2017，10，12： | 3 |
| 7 | Fabrication of Fe nanocomplex pillared few-layered Ti_(3)C_(2)T_(x)MXene with enhanced rate performance for lithium-ion batteries显示文摘Pillaring technologies have been considered as an effective way to improve lithium storage performance of Ti_(3)C_(2)T_(x)MXene.Nevertheless,the pillared hybrids suffer from sluggish Li^(+)diffusion kinetics and electronic transportation due to the compact multi-layered MXene structure,thus exhibiting inferior rate performance.Herein,the few-layered Ti_(3)O_(2)MXene(f-Ti_(3)C_(2)MXene)which is free from restacking can be prepared quickly based on the NH4^(+)ions method.Besides,Fe nanocomplex pillared few-layered Ti_(3)C_(2)T_(x)(FPTC)heterostructures are fabricated via the intercalation of Fe ions into the interlayer of f-Ti_(3)C_(2)MXene.The f-Ti_(3)C_(2)MXene which is immune to restacking can provide a highly conductive substrate for the rapid transport of Li+ions and electrons and possess adequate electrolyte accessible area.Moreover,f-Ti_(3)C_(2)MXene can efficiently relieve the aggregation,prevent the pulverization and buffer the large volume change of Fe nanocomplex during lithiation/delithiation process,leading to enhanced charge transfer kinetics and excellent structural stability of FPTC composites.Consequently,the FPTC hybrids exhibit a high capacity of 535 mAh·g^(-1)after 150 cycles at 0.5 A·g^(-1)and an enhanced rate performance with 310 mAh·g^(-1)after 850 cycles at 5 A·g^(-1).This strategy is facile,universal and can be extended tofabricate various few-layered MXene-derived hybrids with superior rate capability. | Pengfei Huang Shunlong Zhang Hangjun Ying Wentao Yang Jianli Wang Rongnan Guo Weiqiang Han | 2021 | Nano Research2021，14，4： | 3 |
| 8 | Total volatile organic compound concentration and its influencing factors in urban indoor air after decoration显示文摘The indoor total volatile organic compound (TVOC) concentrations and their relationship to potential influencing factors were evaluated. Samples (n = 2302) were collected from 2007 to 2009 both in old structures and new construction in the city of Hangzhou from bedrooms, sitting rooms and studies that had been decorated within the previous year. The average TVOC concentration in all the newly decorated rooms was 0.65±0.69 mg/m 3 . 35.8% of samples exceeded the China standard. Over the past 3 years, the TVOC concentration decreased and then increased (P < 0.05). The percentage of samples exceeding the China standard in the three rooms decreased in the following order: sitting room>study>bedroom. The characteristics of the TVOC source were a key factor influencing the TVOC concentration. In addition, the TVOC concentration was also (P < 0.05) related to the temperature, humidity, time from the end of decoration to sampling (DR), and the amount of time windows and doors were closed before sampling (DC). The temperature and humidity were less important than the DR and DC. A model to relate the TVOC concentration to the five factors (temperature, humidity, source, DR, and DC) was established based on 288 samples (R 2 = 0.83). The model illustrated that the time for the TVOC concentration to meet the China standard was different for the various rooms, and when the other factors were fixed, the impact of DC (t 1 ) on the TVOC concentration could be quantified as (((t 1 +1)/2) 0.212 1)×100%. | LIU Jian Lei BAI Ge CHEN Jie ZHU LiZhong GUO WeiQiang SHEN XueYou | 2011 | Chinese Science Bulletin2011，56，25： | 3 |
| 9 | LA-ICP-MS Zircon U-Pb Dating of Tuffs in the Taining Basin: Constraints on the Ages of the Danxia Red Beds显示文摘Objective Cretaceous terrestrial red beds,as a major component of the Danxia Landform,are widespread in South China.However,the lack of fossils with absolute ages as well as scarce volcanic rocks for isotopic dating to constraint the boundary ages of the red beds results in unclear formation ages of the Danxia red beds.Recently,we have conducted a study of LA-ICP-MS zircon U-Pb dating on the tuffs present at the basal part of the Cretaceous red beds in the Taining Basin,Fujian Province。 | XU Huan GUO Fusheng CHEN Liuqin WANG Chao ZHANG Weiqiang | 2019 | Acta Geologica Sinica(English Edition)2019，93，6： | 1 |
| 10 | Regulation of angiogenesis via Notch signaling in breast cancer and cancer stem cells显示文摘 | Weiqiang Zhou Guangdi Wang Shanchun Guo | 2013 | BBA - Reviews on Cancer2013，，2： | 1 |
| 11 | Prediction of Kovats Retention Index of Saturated Alcohols on Stationary Phases of Different Polarity显示文摘 | WEIQIANG GUO PING ZHU HORST BRODOWSKY | 1997 | Talanta1997，44，： | 1 |
| 12 | Process of Supercritical CO2 Extraction and Improved Design of Extraction Equipment显示文摘 | Guo Jianzhang Zhao Peng Wang Weiqiang | 2011 | Advanced Materials Research2011，221，： | 1 |
| 13 | Model for end-stage liver disease versus the Child-Pugh score in predicting the post-transplant 3-month and 1-year mortality in a cohort of Chinese recipients显示文摘 | Zhiyong Guo Xiaoshun He Linwei Wu Weiqiang Ju Anbin Hu Qiang Tai Dongping Wang Yi Ma Guodong Wang Xiaofeng Zhu Jiefu Huang | 2010 | Surgery Today2010，，1： | 1 |
| 14 | The Application of Artificial Neural Networks in the Study of Quantitative Structure-Retention Relationships for Saturated Alcohols显示文摘 | GUO WEIQIANG LU YANG ZHENG XIAOMING | 2000 | Talanta2000，51，： | 1 |
| 15 | Deep learning-enabled real-time personal handwriting electronic skin with dynamic thermoregulating ability显示文摘The rapid rise of the Internet of things(IoT)have brought the progress of electronic skin(e-skin).E-skin is used to imitate or even surpass the functions of human skin.Thermoregulating is one of the crucial functions of human skin,it is significant to develop a universal way to realize e-skin thermoregulating.Here,inspired by the sweat gland structure in human skin,we report a simple method for achieving dynamic thermoregulating,attributing to the temperature of microencapsulated paraffin remains unchanged when phase change occurs.Combining with the principle of triboelectric nanogenerator,a deep learning model is employed to recognize the output signals of handwriting different letters on ME-skin,and the recognition accuracy reaches 98.13%.Finally,realtime recognition and display of handwritings are successfully implemented by the ME-skin,which provides a general solution for thermoregulating e-skin and application direction for e-skin in the field of IoT. | Shengxin Xiang Jiafeng Tang Lei Yang Yanjie Guo Zhibin Zhao Weiqiang Zhang | 2022 | npj Flexible Electronics2022，6，1： | 1 |
| 16 | Can Immune Cell Function Assay Identify Patients at Risk of Infection or Rejection? A Meta-Analysis显示文摘 | Xiaoting Ling Jun Xiong Wenhua Liang Paul M. Schroder Linwei Wu Weiqiang Ju Yuan Kong Yushu Shang Zhiyong Guo Xiaoshun He | 2012 | Transplantation2012，，7： | 1 |
| 17 | Model for end-stage liver disease versus the Child-Pugh score in predicting the post-transplant 3-month and 1-year mortality in a cohort of Chinese recipients显示文摘 | Zhiyong Guo Xiaoshun He Linwei Wu Weiqiang Ju Anbin Hu Qiang Tai Dongping Wang Yi Ma Guodong Wang Xiaofeng Zhu Jiefu Huang | 2010 | Surgery Today2010，，1： | 1 |
| 18 | Prognostic impact of MMP‐2 and MMP‐9 expression in pathologic stage IA non‐small cell lung cancer 显示文摘 | Wenlong Shao Wei Wang Xin‐guo Xiong Christopher Cao Tristan D. Yan Guoqin Chen Hanzhang Chen Weiqiang Yin Jun Liu Yingying Gu Mingcong Mo Jianxing He | 2011 | J. Surg. Oncol2011，，： | 1 |
| 19 | Living donor liver transplantation versus deceased donor liver transplantation for hepatocellular carcinoma: A meta‐analysis显示文摘 | Wenhua Liang Linwei Wu Xiaoting Ling Paul M. Schroder Weiqiang Ju Dongping Wang Yushu Shang Yuan Kong Zhiyong Guo Xiaoshun He | 2012 | Liver Transpl2012，，10： | 1 |
| 20 | Dynamic modeling of tectonic carbon processes:State of the art and conceptual workflow显示文摘Plate tectonics plays a critical role in modulating atmospheric CO_(2)concentration on the geological timescale(≥106year).A growing consensus on tectonic and Earth’s CO_(2)history in the Cenozoic and deeper time provides solid restrictions and standards for testing tectonic carbon processes against global measurements.Despite this,modeling the causal relationship between tectonic events and atmospheric CO_(2)levels remains a challenge.We examine the current state of the global tectonic CO_(2)research and suggest a conceptual workflow for numerical experiments that integrates plate tectonics and deep carbon dynamics.Future tectonic carbon cycle modeling should include at least four modules:(1)simulation of carbon-carrying processes,such as carbon ingassing and outgassing at the scale of minerals;(2)calculation of CO_(2)fluxes in tectonic settings like subduction,mantle plume,and plate rifting;(3)reconstruction of carbon cycling within the plates-scale tectonic scenario,particularly involving the processes of supercontinent convergence and dispersion;and(4)comparison with atmospheric CO_(2)history data and iterations,aiming to find the coincidental link between different tectonic carbon fluxes and climate changes.According to our analysis,the recent advancements in each of the four modules have paved the path for a more general assembly.We envision that the large variety of carbon transportation parameters across more than ten orders of magnitude in both time and space is the primary technical hurdle in simulating tectonic carbon dynamics.We propose a boundary-condition-connected approach for simulating the global carbon cycle to realize carbon exchange between the solid earth and surface spheres. | Liang ZHAO Zhengtang GUO Huaiyu YUAN Xinxin WANG Hao SHEN Jianfeng YANG Baolu SUN Ning TAN Hui ZHANG Yonggang LIU Yang LI Jiamin WANG Weiqiang JI Rixiang ZHU | 2023 | Science China Earth Sciences2023，66，3： | 1 |
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