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| 1 | Polyorogenic evolution of the Paleoproterozoic Trans-North China Belt--New insights from the Luliangshan-Hengshan-Wutaishan and Fuping massifs显示文摘 | Michel Faure Pierre Trap Wei Line Patrick Monié Olivier Bruguier | 2007 | Episodes2007，30，2： | 63 |
| 2 | Blockade of Tim-3 Pathway Ameliorates Interferon-γ Production from Hepatic CD8^+ T Cells in a Mouse Model of Hepatitis B Virus Infection显示文摘T cell immunoglobulin-and mucin-domain-containing molecule-3(Tim-3) has been reported to participate in the pathogenesis of inflammatory diseases. However,whether Tim-3 is involved in hepatitis B virus(HBV) infection remains unknown. Here,we studied the expression and function of Tim-3 in a hydrodynamics-based mouse model of HBV infection. A significant increase of Tim-3 expression on hepatic T lymphocytes,especially on CD8+ T cells,was demonstrated in HBV model mice from day 7 to day 18. After Tim-3 knockdown by specific shRNAs,significantly increased IFN-γ production from hepatic CD8+ T cells in HBV model mice was observed. Very interestingly,we found Tim-3 expression on CD8+ T cells was higher in HBV model mice with higher serum anti-HBs production. Moreover,Tim-3 knockdown influenced anti-HBs production in vivo. Collectively,our data suggested that Tim-3 might act as a potent regulator of antiviral T-cell responses in HBV infection. | Ying Ju Nan Hou Xiaoning Zhang Di Zhao Ying Liu Jinjin Wang Fang Luan Wei Shi Faliang Zhu Wensheng Sun Lining Zhang Chengjiang Gao Lifen Gao Xiaohong Liang Chunhong Ma | 2009 | Cellular & Molecular Immunology2009，6，1： | 19 |
| 3 | Bio-Inspired Controller for a Robot Cheetah with a Neural Mechanism Controlling Leg Muscles显示文摘 | Xin Wang Mantian Li Pengfei Wang Wei Guo Lining Sun | 2012 | Journal of Bionic Engineering2012，9，3： | 18 |
| 4 | CPG Control for Biped Hopping Robot in Unpredictable Environment显示文摘 | Tingting Wang Wei Guo Mantian Li Fusheng Zha Lining Sun | 2012 | Journal of Bionic Engineering2012，9，1： | 17 |
| 5 | Ginsenoside Rb1 attenuates activated microglia-induced neuronal damage显示文摘The microglia-mediated inflammatory reaction promotes neuronal damage under cerebral ischemia/hypoxia conditions. We therefore speculated that inhibition of hypoxia-induced microglial activation may alleviate neuronal damage. To test this hypothesis, we co-cultured ginsenoside Rb1, an active component of ginseng, and cortical neurons. Ginsenoside Rb1 protected neuronal morphology and structure in a single hypoxic culture system and in a hypoxic co-culture system with microglia, and reduced neuronal apoptosis and caspase-3 production. The protective effect was observable prior to placing in co-culture. Additionally, ginsenoside Rb1 inhibited levels of tumor necrosis factor-α in a co-culture system containing activated N9 microglial cells. Ginsenoside Rb1 also significantly decreased nitric oxide and superoxide production induced by N9 microglia. Our findings indicate that ginsenoside Rb1 attenuates damage to cerebral cortex neurons by downregulation of nitric oxide, superoxide, and tumor necrosis factor-α expression in hypoxia-activated microglia. | Lining Ke Wei Guo Jianwen Xu Guodong Zhang Wei Wang Wenhua Huang | 2014 | Neural Regeneration Research2014，9，3： | 11 |
| 6 | Recent progress of energy transfer and luminescence intensity boosting mechanism in Nd3+-sensitized upconversion nanoparticles显示文摘Rare earth doped upconversion nanoparticles can be considered as the spice of research in the field of luminescence nanomaterials due to their unique optical properties such as near-infrared excitation.Enormous works have been reported about biomedical applications of 980 nm excited and Yb^3+-sensitized upconversion nanoparticles.However,980 nm excitation wavelength overlaps with the absorption band of water molecules in the biological environment,leading to overheating effect that can induce thermal damages of normal cells and tissues.Recently,Nd^3+-sensitized upconversion nanoparticles which can be excited with 808 nm has been widely investigated as alternative nanoparticles that can surmount this issue of overheating effect.Even though Nd^3+-sensitized upconversion nanoparticles can reduce the overheating effect by 20 fold as compared to Yb^3+-sensitized counterpart,there are several factors that reduce the upconversion luminescence intensity.In this review article,photon energy harvesting and transferring mechanisms in Nd^3+,Yb^3+and emitter ions co-doped upconversion nanoparticles under 808 nm excitation are briefly discussed.Factors that affect upconversion luminescence intensity and quantum yield of Nd^3+-sensitized upconversion nanoparticles are also addressed.Besides,some of the important strategies that have been recently utilized to boost upconversion luminescence intensity of Nd^3+sensitized upco nversion nanoparticles are tho roughly summarized.Lastly,the future challenges in the area and our perspectives are in sight. | Solomon Tiruneh Dibaba Xiaoqian Ge Wei Ren Lining Sun | 2019 | Journal of Rare Earths2019，37，8： | 9 |
| 7 | OSBPL2-disrupted pigs recapitulate dual features of human hearing loss and hypercholesterolaemia显示文摘Oxysterol binding protein like 2(OSBPL2), an important regulator in cellular lipid metabolism and transport, was identified as a novel deafness-causal gene in our previous work. To resemble the phenotypic features of OSBPL2 mutation in animal models and elucidate the potential genotypephenotype associations, the OSBPL2-disrupted Bama miniature(BM) pig model was constructed using CRISPR/Cas9-mediated gene editing, somatic cell nuclear transfer(SCNT) and embryo transplantation approaches, and then subjected to phenotypic characterization of auditory function and serum lipid profiles. The OSBPL2-disrupted pigs displayed progressive hearing loss(HL) with degeneration/apoptosis of cochlea hair cells(HCs) and morphological abnormalities in HC stereocilia, as well as hypercholesterolaemia. High-fat diet(HFD) feeding aggravated the development of HL and led to more severe hypercholesterolaemia. The dual phenotypes of progressive HL and hypercholesterolaemia resembled in OSBPL2-disrupted pigs confirmed the implication of OSBPL2 mutation in nonsydromic hearing loss(NSHL) and contributed to the potential linkage between auditory dysfunction and dyslipidaemia/hypercholesterolaemia. | Jun Yao Huasha Zeng Min Zhang Qinjun Wei Ying Wang Haiyuan Yang Yajie Lu Rongfeng Li Qiang Xiong Lining Zhang Zhibin Chen Guangqian Xing Xin Cao Yifan Dai | 2019 | Journal of Genetics and Genomics2019，46，8： | 7 |
| 8 | An epidermal sEMG tattoo-like patch as a new human–machine interface for patients with loss of voice显示文摘Throat cancer treatment involves surgical removal of the tumor,leaving patients with facial disfigurement as well as temporary or permanent loss of voice.Surface electromyography(sEMG)generated from the jaw contains lots of voice information.However,it is difficult to record because of not only the weakness of the signals but also the steep skin curvature.This paper demonstrates the design of an imperceptible,flexible epidermal sEMG tattoo-like patch with the thickness of less than 10μm and peeling strength of larger than 1N cm−1 that exhibits large adhesiveness to complex biological surfaces and is thus capable of sEMG recording for silent speech recognition.When a tester speaks silently,the patch shows excellent performance in recording the sEMG signals from three muscle channels and recognizing those frequently used instructions with high accuracy by using the wavelet decomposition and pattern recognization.The average accuracy of action instructions can reach up to 89.04%,and the average accuracy of emotion instructions is as high as 92.33%.To demonstrate the functionality of tattoo-like patches as a new human–machine interface(HMI)for patients with loss of voice,the intelligent silent speech recognition,voice synthesis,and virtual interaction have been implemented,which are of great importance in helping these patients communicate with people and make life more enjoyable. | Huicong Liu Wei Dong Yunfei Li Fanqi Li Jiangjun Geng Minglu Zhu Tao Chen Hongmiao Zhang Lining Sun Chengkuo Lee | 2020 | Microsystems & Nanoengineering2020，6，1： | 6 |
| 9 | A formal semantics for program debugging显示文摘This work aims to build a semantic framework for automated debugging.A debugging process consists of tracing,locating,and fixing processes consecutively.The first two processes are accomplished by a tracing procedure and a locating procedure,respectively.The tracing procedure reproduces the execution of the failed test case with well-designed data structures and saves necessary information for locating bugs.The locating procedure will use the information obtained from the tracing procedure to locate ill-designed statements and to generate a system of fix-equations,whose solution will be used to fix the bugs.A structural operational semantics is given to define the functions of the tracing and locating procedures.Both of them are proved to terminate.The main task of fixing process is to solve the fix-equations.It turns out that for a given failed test case,there exist four types of fix-equations and three dierent solutions:1)The bug is solvable,i.e.,there exists a solution of the system of fix-equations,and the program can be repaired.2)There exists a structural design error in the program,i.e.,the system of fix-equations generated at each round of the locating procedure is solvable,but a new bug will arise when the old bug is being fixed.3)There exists a logical design error,and the system of fix-equations is not solvable. | LI Wei LINing | 2012 | Science China(Information Sciences)2012，55，1： | 4 |
| 10 | A 6.2–9.5 GHz receiver for Wimedia MB-OFDM and China UWB standard显示文摘An integrated 6.2–9.5 GHz UWB receiver for both WiMedia MB-OFDM and China UWB standard is proposed. The receiver can cover Group#3, Group#4 for WiMedia and Group#2–5 for China UWB standard respectively. The fully differential receiver consists of a wideband LNA and a down conversion mixer with high gain and low gain mode. A low-pass filter with controllable gain and cut-o? frequency along with a programmable gain amplifier are also included. The chip was fabricated in TSMC 0.13-μm RF CMOS process. Measurement results show that the receiver achieves voltage gain from 21 to 69 dB with 2 dB/step and an NF of 3.2–4.6 dB over 6.2–9.5 GHz and 1-dB compression point of ?21 dBm. The intermediate frequency of the receiver can be switched between 264 and 132 MHz, which enables the receiver applicable for both WiMedia and China UWB standard. Power consumption is only 47 mA with 1.2–V supply voltage. | GAO Ting ZHOU Feng LI Wei LAN Fei LINing REN JunYan | 2011 | Science China(Information Sciences)2011，54，2： | 4 |
| 11 | Fine particulate matter(PM_(2.5)/PM_(1.0)) in Beijing,China: Variations and chemical compositions as well as sources显示文摘Particulate matter(i.e.,PM_(1.0) and PM_(2.5)),considered as the key atmospheric pollutants,exerts negative effects on visibility,global climate,and human health by associated chemical compositions.However,our understanding of PM and its chemical compositions in Beijing under the current atmospheric environment is still not complete after witnessing marked alleviation during 2013–2017.Continuous measurements can be crucial for further air quality improvement by better characterizing PM pollution and chemical compositions in Beijing.Here,we conducted simultaneous measurements on PM in Beijing during 2018–2019.Results indicate that annualmean PM_(1.0) and PM_(2.5) concentrations were 35.49±18.61μg/m^(3) and 66.58±60.17μg/m^(3),showing a positive response to emission controls.The contribution of sulfate,nitrate,and ammonium(SNA)played an enhanced role with elevated PM loading and acted as the main contributors to pollution episodes.Discrepancies observed among chemical species between PM_(1.0) and PM_(2.5) in spring suggest that sand particles trend to accumulate in the range of 1–2.5μm.Pollution episodes occurred accompanied with southerly clusters and high formation of SNA by heterogeneous reactions in summer and winter,respectively.Results from positive matrix factorization(PMF)combined with potential source contribution function(PSCF)models showed that potential areas were seasonal dependent,secondary and vehicular sources became much more important compared with previous studies in Beijing.Our study presented a continuous investigation on PM and sources origins in Beijing,which provides a better understanding for further emission control as well as a reference for other cities in developing countries. | Lining Luo Xiaoxuan Bai Shuhan Liu Bobo Wu Wei Liu Yunqian Lv Zhihui Guo Shumin Lin Shuang Zhao Yan Hao Jiming Hao Kai Zhang Aihua Zheng Hezhong Tian | 2022 | Journal of Environmental Sciences2022，34，11： | 3 |
| 12 | Study of an inchworm-like micro-robot显示文摘 | 李满天 Guo Wei Sun Lining | 2006 | High Technology Letters2006，12，2： | 3 |
| 13 | Velocity Control of a Bounding Quadruped via Energy Control and Vestibular Reflexes显示文摘 | Xin Wang Mantian Li Wei Guo Pengfei Wang Lining Sun | 2014 | Journal of Bionic Engineering2014，11，4： | 3 |
| 14 | A current-mode RF transmitter for 6–9 GHz MB-OFDM UWB application显示文摘This paper presents a current-mode 6–9 GHz RF transmitter for MB-OFDM UWB systems. The proposed current-mode transmitter consists of current-mode IQ LPF, current mirror amplifier, IQ up-conversion mixer (up-mixer), differential power driver amplifier (PA) and high-speed divider with LO buffers for generating IQ LO signals. All circuits are designed to possess high linearity and wide bandwidth. The transmitter is fabricated in TSMC 0.13 μm 1P8M RF CMOS technology with a die area of 1.56 mm2. Measurement results show that a maximum output power of -0.7 dBm with an LO leakage/sideband rejection ratio (LOL/SB RR) around -33/ - 35 dBc is achieved, and that this transmitter excels the traditional voltage-mode counterpart in terms of high linearity (about +1 dBm output 1-dB compression point, +10 dBm output IP3 in average) with comparable power consumption (drawing 48 mA current from 1.2 V supply). | CHEN YunFeng FAN JinHan LI Wei LINing REN JunYan | 2011 | Science China(Information Sciences)2011，54，2： | 2 |
| 15 | Proceedings of the international conference on fiber reinforced concrete显示文摘 | SHIEN LI GUIHUI WEI LINING YAO | 1997 | Guangzhou:Guangdong Science and Technology Press1997，2733，： | 1 |
| 16 | Multi- objective flexible job shop schedule: design and evalu- ation by simulation modeling显示文摘 | Xing Lining Chen Ying-wu Yang Ke wei | 2009 | Applied Soft Com- puting2009，9，： | 1 |
| 17 | Structural geology and favorable exploration prospect belts in northwestern Sichuan Basin, SW China显示文摘The northwestern Sichuan region has experienced multi-stage tectonic evolution including marine cratonic basin from the Sinian to the Middle Triassic and intra-continental basin from the Late Triassic to the Cenozoic. Several regional tectonic activities caused complicated stratigraphic distribution and structural deformations in the deep-buried layers. During the key tectonic periods, some characteristic sedimentary and deformation structures were formed, including the step-shaped marginal carbonate platform of Dengying Formation, the western paleo-high at the end of Silurian, and the passive continental margin of the Late Paleozoic–Middle Triassic. The Meso-Cenozoic intra-continental compressional tectonic processes since the Late Triassic controlled the formation of complex thrusting structures surrounding and inside the northwestern basin. The northern Longmenshan fold-thrust belt has a footwall in-situ thrust structure,which is controlled by two sets of detachments in the Lower Triassic and Lower Cambrian and presents as a multi-level deformation structure with the shallow folds, the middle thin-skin thrusts and the deeper basement-involved folds. The thrust belt in front of the Micangshan Mountain shows a double-layer deformation controlled by the Lower Triassic salt detachment, which is composed by the upper monocline and deep-buried imbricate thrust structures. The interior of the basin is characterized by several rows of large-scale basement-involved folds with NEE strike direction. From the perspective of structural geology, the favorable exploration reservoirs and belts in northwestern Sichuan have obvious zoning characteristics. The favorable exploration layers of Dengying Formation of Upper Sinian are mainly distributed in the eastern and northern areas of the northwestern Sichuan Basin, in which the Jiulongshan structural belt, Zitong syncline and Yanting slope are the most favorable. The Lower Paleozoic was transformed by Caledonian paleo-uplift and late Cenozoic folding, and the midwest area such as the Zitong syncline is a potential area for hydrocarbon exploration. The favorable part of the Upper Paleozoic is mainly distributed in the northern Longmenshan belt and its frontal area, where the deep-buried thin-skin thrust structures in the footwall are the key exploration targets. | CHEN Zhuxin LI Wei WANG Lining LEI Yongliang YANG Guang ZHANG Benjian YIN Hong YUAN Baoguo | 2019 | Petroleum Exploration and Development2019，46，2： | 1 |
| 18 | Stiffness research on a high-precision,large-workspace parallel mechanism with com- pliant joints 显示文摘 | Dong Wei Sun Lining Du Zhijiang | 2008 | Precision Engineering2008，32，3： | 1 |
| 19 | Corrosion of Cr Bearing Low Alloy Pipeline Steel in CO2 Environment at Static and Flowing Conditions 显示文摘 | Xu Lining Guo Shaoqiang Chang Wei | 2013 | Applied Surface Science2013，270，4： | 1 |
| 20 | Design of a precision compliant parallel positioner driven by dual piezoelectric actuators显示文摘 | DONG Wei SUN Lining DU Zhijiang | 2007 | Sensors and Actuators A: Physical2007，135，1： | 1 |
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