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| 1 | Control of a Quadruped Robot with Bionic Springy Legs in Trotting Gait显示文摘 | Mantian Li Zhenyu Jiang Pengfei Wang Lining Sun Shuzhi Sam Ge | 2014 | Journal of Bionic Engineering2014，11，2： | 25 |
| 2 | Blockade of Tim-3 Pathway Ameliorates Interferon-γ Production from Hepatic CD8^+ T Cells in a Mouse Model of Hepatitis B Virus Infection显示文摘T cell immunoglobulin-and mucin-domain-containing molecule-3(Tim-3) has been reported to participate in the pathogenesis of inflammatory diseases. However,whether Tim-3 is involved in hepatitis B virus(HBV) infection remains unknown. Here,we studied the expression and function of Tim-3 in a hydrodynamics-based mouse model of HBV infection. A significant increase of Tim-3 expression on hepatic T lymphocytes,especially on CD8+ T cells,was demonstrated in HBV model mice from day 7 to day 18. After Tim-3 knockdown by specific shRNAs,significantly increased IFN-γ production from hepatic CD8+ T cells in HBV model mice was observed. Very interestingly,we found Tim-3 expression on CD8+ T cells was higher in HBV model mice with higher serum anti-HBs production. Moreover,Tim-3 knockdown influenced anti-HBs production in vivo. Collectively,our data suggested that Tim-3 might act as a potent regulator of antiviral T-cell responses in HBV infection. | Ying Ju Nan Hou Xiaoning Zhang Di Zhao Ying Liu Jinjin Wang Fang Luan Wei Shi Faliang Zhu Wensheng Sun Lining Zhang Chengjiang Gao Lifen Gao Xiaohong Liang Chunhong Ma | 2009 | Cellular & Molecular Immunology2009，6，1： | 19 |
| 3 | Bio-Inspired Controller for a Robot Cheetah with a Neural Mechanism Controlling Leg Muscles显示文摘 | Xin Wang Mantian Li Pengfei Wang Wei Guo Lining Sun | 2012 | Journal of Bionic Engineering2012，9，3： | 18 |
| 4 | CPG Control for Biped Hopping Robot in Unpredictable Environment显示文摘 | Tingting Wang Wei Guo Mantian Li Fusheng Zha Lining Sun | 2012 | Journal of Bionic Engineering2012，9，1： | 17 |
| 5 | Evidences of rapid erosion driven by climate in the Yarlung Zangbo (Tsangpo) Great Canyon,the eastern Himalayan syntaxis显示文摘Climate and tectonism are both particularly intense in the Yarlung Zangbo (Tsangpo) Great Canyon in the eastern Himalayan syntaxis,which is characterized by the most rapid landscape evolution of anywhere in the world.Thus,the eastern Himalayan syntaxis is one of the best locations to study the interactions between climate and tectonics.This paper investigates the cooling ages of the Doxong La-Baibung profile using apatite fission track (AFT) dating on 11 bedrock samples at elevations ranging from 4210 to 710 m.There are topographic,climatic,metamorphic,and thermochronological gradients in the profile,providing good conditions to study interactions between climate and tectonics.AFT ages ranged from 4.6±0.6 Ma to 1.7±0.3 Ma,and the mean fission track lengths ranged from 11.0 to 12.4 μm.It was found that the cooling rates revealed by AFT ages increased with decreasing elevation.However,the tendency of the cooling rates revealed by the 40 Ar-39 Ar ages was different from that indicated by the AFT ages.Moreover,for most districts of the eastern Himalayan syntaxis,the compiled AFT age distribution correlates well with the annual average precipitation,indicating the coupling of the cooling and erosion rates of the near-surface rock and precipitation.The geothermal history modeling results indicate an obvious increase in the cooling and erosion rate between 1.0 and 0.5 Ma.This age is consistent with other research findings for this time,when the vapor channel of the Yarlung Zangbo Great Canyon began to take effect.These evidences suggest that climate,especially precipitation,has acting as a key factor influencing the rapid cooling and erosion in the Yarlung Zangbo Great Canyon since 1-0.5 Ma. | YU XiangJiang JI JianQing GONG JunFeng SUN DongXia QING JianChun WANG LiNing ZHONG DaLai ZHANG ZhiCheng | 2011 | Chinese Science Bulletin2011，56，11： | 11 |
| 6 | Design of a control system for a macro-micro dual-drive high acceleration high precision positioning stage for IC packaging显示文摘A macro-micro dual-drive positioning system showing good potential for high acceleration and high precision positioning required in IC packaging applications is devised in this paper. The dual-drive positioning stage uses a VCM (voice coil motor) driven macro positioning stage and a PZT piezo-electric driven micro positioning stage. The coupling characteristics of the system are analyzed to produce a control structure with a micro positioning stage that can dynamically compensate for the positioning error produced by the macro positioning stage. Models of the two positioning stages are described. The models cover both the mechanism and the actuator. For the macro positioning stage, friction characteristics are taken into account, and a controller with an LQG (linear-quadratic-Gaussian) control algorithm combining a feed-forward compensation algorithm is derived. A PID controller is used to control the micro positioning stage. Detailed designs are derived for the proposed approach, and the performance is validated by simulation. | LIU YanJie LI Teng SUN LiNing | 2009 | Science China(Technological Sciences)2009，52，7： | 10 |
| 7 | Recent progress of energy transfer and luminescence intensity boosting mechanism in Nd3+-sensitized upconversion nanoparticles显示文摘Rare earth doped upconversion nanoparticles can be considered as the spice of research in the field of luminescence nanomaterials due to their unique optical properties such as near-infrared excitation.Enormous works have been reported about biomedical applications of 980 nm excited and Yb^3+-sensitized upconversion nanoparticles.However,980 nm excitation wavelength overlaps with the absorption band of water molecules in the biological environment,leading to overheating effect that can induce thermal damages of normal cells and tissues.Recently,Nd^3+-sensitized upconversion nanoparticles which can be excited with 808 nm has been widely investigated as alternative nanoparticles that can surmount this issue of overheating effect.Even though Nd^3+-sensitized upconversion nanoparticles can reduce the overheating effect by 20 fold as compared to Yb^3+-sensitized counterpart,there are several factors that reduce the upconversion luminescence intensity.In this review article,photon energy harvesting and transferring mechanisms in Nd^3+,Yb^3+and emitter ions co-doped upconversion nanoparticles under 808 nm excitation are briefly discussed.Factors that affect upconversion luminescence intensity and quantum yield of Nd^3+-sensitized upconversion nanoparticles are also addressed.Besides,some of the important strategies that have been recently utilized to boost upconversion luminescence intensity of Nd^3+sensitized upco nversion nanoparticles are tho roughly summarized.Lastly,the future challenges in the area and our perspectives are in sight. | Solomon Tiruneh Dibaba Xiaoqian Ge Wei Ren Lining Sun | 2019 | Journal of Rare Earths2019，37，8： | 9 |
| 8 | Synergistic therapy of magnetism-responsive hydrogel for soft tissue injuries显示文摘Soft tissue injury is very common and associated with pain,tissue swelling and even malformation if not treated on time.Treating methods include cryotherapy,electrical therapy,ultrasound therapy and anti-inflammatory drug,but none of them is completely satisfying.In this work,for a better therapeutic effect,drug therapy and pulsed electromagnetic field(PEMF)therapy were combined.We constructed a drug delivery system using the tetra-PEG/agar hydrogel(PA).By incorporating Fe3O4 NPs into the hydrogel network,a magnetism-responsive property was achieved in the system.The cytotoxicity and in vivo study showed a good biocompatibility of the PA/Fe3O4 hydrogel.A magnetism-controlled release was attained by the incorporation of Fe3O4.Finally,in vivo study showed a better performance of the DS-loaded PA/Fe3O4 compared with the commercially available DS ointment regarding the recovery of the injured soft tissue.Therefore,this magnetism-responsive hydrogel may represent a promising alternative to treat soft tissue injury. | Lining Zhang Xiuqin Zuo Shengjie Li Mi Sun Huimin Xie Kai Zhang Jikun Zhou Liyun Che Junxuan Ma Zishan Jia Fei Yang | 2019 | Bioactive Materials2019，4，1： | 7 |
| 9 | An epidermal sEMG tattoo-like patch as a new human–machine interface for patients with loss of voice显示文摘Throat cancer treatment involves surgical removal of the tumor,leaving patients with facial disfigurement as well as temporary or permanent loss of voice.Surface electromyography(sEMG)generated from the jaw contains lots of voice information.However,it is difficult to record because of not only the weakness of the signals but also the steep skin curvature.This paper demonstrates the design of an imperceptible,flexible epidermal sEMG tattoo-like patch with the thickness of less than 10μm and peeling strength of larger than 1N cm−1 that exhibits large adhesiveness to complex biological surfaces and is thus capable of sEMG recording for silent speech recognition.When a tester speaks silently,the patch shows excellent performance in recording the sEMG signals from three muscle channels and recognizing those frequently used instructions with high accuracy by using the wavelet decomposition and pattern recognization.The average accuracy of action instructions can reach up to 89.04%,and the average accuracy of emotion instructions is as high as 92.33%.To demonstrate the functionality of tattoo-like patches as a new human–machine interface(HMI)for patients with loss of voice,the intelligent silent speech recognition,voice synthesis,and virtual interaction have been implemented,which are of great importance in helping these patients communicate with people and make life more enjoyable. | Huicong Liu Wei Dong Yunfei Li Fanqi Li Jiangjun Geng Minglu Zhu Tao Chen Hongmiao Zhang Lining Sun Chengkuo Lee | 2020 | Microsystems & Nanoengineering2020，6，1： | 6 |
| 10 | Key Problems in Microforming Processes of Microparts显示文摘从生产工程的观点, microforming 被看作 aneffective 过程在 microforming processeswere investigated.A 制作各种各样的 microparts.Several 钥匙问题有高僵硬的新 microforming 仪器 thepunch 司机被开发生产 microparts.To 的压电的致动器改进形成的能力并且定位 thebillets ,漂浮的 microdie 是营舍的 designed.The 尺寸效果并且死 themicroforming 能力上的洞与 upsetti | Chunju WANG Debin SHAN Bin GUO Jian ZHOU Lining SUN | 2007 | Journal of Materials Science & Technology2007，23，2： | 6 |
| 11 | An in-pipe micro robot actuated by piezoelectric bimorphs显示文摘A novel in-pipe micro robot providing stable and accurate locomotion inside a tubular structure with diameters ranging from 16 mm to 18 mm is presented in this paper. Driven by impulsive voltages, deflections of the piezoelectric bimorphs are generated and then converted into translational locomotion by the principle of the Impact Drive Mechanism (IDM). Theoretical analysis of the proposed system is performed based on a simplified mechanical model. Then dynamic simulations of the dynamic behavior are performed. Finally, an experiment is conducted to investigate the moving ability of this device. The results demonstrate that a maximum translational velocity of 3.5 mm/s can be obtained under an impulsive driving voltage with peak value at 50 V and frequency of 1100 Hz. Both theoretical analysis and experimental trials prove that the principle of IDM actuated by piezoelectric bimorphs is feasible and robust for achieving accurate locomotion of the micro robot in pipes with diameters of less than 20 mm. | LIU PinKuan WEN ZhiJie SUN LiNing | 2009 | Chinese Science Bulletin2009，54，12： | 5 |
| 12 | A new method for splice site prediction based on the sequence patterns of splicing signals and regulatory elements显示文摘It is of significance for splice site prediction to develop novel algorithms that combine the sequence patterns of regulatory elements such as enhancers and silencers with the patterns of splicing signals.In this paper,a statistical model of splicing signals was built based on the entropy density profile(EDP) method,weight array method(WAM) and κ test;moreover,the model of splicing regulatory elements was developed by an unsupervised self-learning method to detect motifs associated with regulatory elements.With two models incorporated,a multi-level support vector machine(SVM) system was de-vised to perform ab initio prediction for splice sites originating from DNA sequence in eukaryotic ge-nome.Results of large scale tests on human genomic splice sites show that the new method achieves a comparative high performance in splice site prediction.The method is demonstrated to be with at least the same level of performance and usually better performance than the existing SpliceScan method based on modeling regulatory elements,and shown to have higher accuracies than the traditional methods with modeling splicing signals such as the GeneSplicer.In particular,the method has evident advantage over splice site prediction for the genes with lower GC content. | SUN ZongXiao SANG LingJie JU LiNing ZHU HuaiQiu | 2008 | Chinese Science Bulletin2008，53，21： | 3 |
| 13 | Study of an inchworm-like micro-robot显示文摘 | 李满天 Guo Wei Sun Lining | 2006 | High Technology Letters2006，12，2： | 3 |
| 14 | Velocity Control of a Bounding Quadruped via Energy Control and Vestibular Reflexes显示文摘 | Xin Wang Mantian Li Wei Guo Pengfei Wang Lining Sun | 2014 | Journal of Bionic Engineering2014，11，4： | 3 |
| 15 | Lanthanide-doped heterostructured nanocomposites toward advanced optical anti-counterfeiting and information storage显示文摘The continuously growing importance of information storage,transmission,and authentication impose many new demands and challenges for modern nano-photonic materials and information storage technologies,both in security and storage capacity.Recently,luminescent lanthanide-doped nanomaterials have drawn much attention in this field because of their photostability,multimodal/multicolor/narrowband emissions,and long luminescence lifetime.Here,we report a multimodal nanocomposite composed of lanthanide-doped upconverting nanoparticle and EuSe semiconductor,which was constructed by utilizing a cation exchange strategy.The nanocomposite can emit blue and white light under 365 and 394 nm excitation,respectively.Meanwhile,the nanocomposites show different colors under 980 nm laser excitation when the content of Tb3+ions is changed in the upconversion nanoparticles.Moreover,the time-gating technology is used to filter the upconversion emission of a long lifetime from Tb3+or Eu3+,and the possibilities for modulating the emission color of the nanocomposites are further expanded.Based on the advantage of multiple tunable luminescence,the nanocomposites are designed as optical modules to load optical information.This work enables multi-dimensional storage of information and provides new insights into the design and fabrication of next-generation storage materials. | Yao Xie Yapai Song Guotao Sun Pengfei Hu Artur Bednarkiewicz Lining Sun | 2022 | Light(Science & Applications)2022，11，6： | 3 |
| 16 | The Anti-inflammatory TIPE2 Is an Inhibitor of the Oncogenic Ras显示文摘 | Yael Gus-Brautbar Derek Johnson Li Zhang Honghong Sun Peng Wang Shirley Zhang Lining Zhang Youhai H. Chen | 2012 | Molecular Cell2012，，5： | 2 |
| 17 | A robotic tele-drill system over network using predictive display显示文摘 | 谢小辉 Sun Lining Du Zhijiang Cai Hegao | 2006 | High Technology Letters2006，12，1： | 2 |
| 18 | Wheeled foot quadruped robot HITAN-I显示文摘 | 王鹏飞 Sun Lining | 2006 | High Technology Letters2006，12，4： | 2 |
| 19 | Stiffness research on a high-precision,large-workspace parallel mechanism with com- pliant joints 显示文摘 | Dong Wei Sun Lining Du Zhijiang | 2008 | Precision Engineering2008，32，3： | 1 |
| 20 | Lanthanide complexes-functionalized ordered mesoporous TiO_2:Multicolor emission(visible and near-infrared luminescence) based on visible-light sensitization显示文摘Recently,much attention has been paid to the lanthanide luminescent materials based on the visiblelight sensitization for their potential applications in the fields of bio-imaging and optical devices.In this work,the lanthanide complexes have been covalently bonded to the ordered mesoporous titania(OMT) matrix,and the resulting titania-based hybrid ordered mesoporous materials(named as LnDBOMT,Ln = Eu,Sm,Yb,Nd) were characterized by using Fourier-transform infrared(FT-IR) spectroscopy,small-angle X-ray powder diffraction(SAXD),N_2 adsorption-desorption isotherms,transmission electron microscopy(TEM),fluorescence spectroscopy,and thermogravimetric analysis.Generally,exciting with visible light is advantageous over UV excitation.Of importance here is that,under excitation with visible light,the LnDB-OMT all show characteristic visible(Eu^(3+),Sm^(3+)) as well as nearinfrared(Sm^(3+),Yb^(3+),Nd^(3+)) luminescence of the corresponding Ln^(3+) ions(multicolor emission covered from 500 to 1400 nm spectral region),which is attributed to the energy transfer from the ligands to the Ln^(3+) ions via an antenna effect. | Zhijuan Wang Song Dang Shu'na Zhao Lining Sun | 2018 | Journal of Rare Earths2018，36，9： | 1 |
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