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| 1 | Development and prospect of direct‐current circuit breaker in China显示文摘The direct‐current circuit breaker(DCCB)is the most ideal choice for DC fault isolation in DC grids.Despite a late start,China's research and development on the DCCB have made outstanding achievements.This article provides a brief glance of current China's DCCB development status.It begins by sorting out the technical route according to the topology of DCCB.Then it systematically summarises both mechanical and hybrid DCCBs with focussing on the aspects of topology structure and principle,key technology and characteristics,prototype development and application.It is apparent that Chinese scientists and engineers confronted the worldwide problem of large capacity DC breaking,and put forward a comprehensive solution which consists of an innovative topology structure based on coupled negative voltage circuit,breaking throughs on the key technologies such as highly controllable and reliable fault current commutation,millisecond‐level ultra‐fast and efficient electromagnetic repulsion mechanism,high tolerance and high stability power electronic switch,low residual voltage and fast response energy consumption device,etc.The article states that the world's first set of hybrid high‐voltage(HV)DCCB,and the first set of mechanical HV DCCB have been developed.These DCCBs will soon be deployed to the DC grids which have the highest voltage levels therefore require the strongest breaking capacity.These achievements are leading the world in the development and application of DCCB.The article also discusses the overall development trends of DCCB in the areas of new topologies,key techno-logical breakthroughs and application scenarios,etc.These discussions serve as references for DCCB's future technological advancement and its ever‐expanding applications. | Weijiang Chen Rong Zeng Junjia He Yi Wu Xiaoguang Wei Taixun Fang Zhanqing Yu Zhao Yuan Yifei Wu Wandi Zhou Bing Yang Lu Qu | 2021 | High Voltage2021，6，1： | 6 |
| 2 | Protective effects of Buyinqianzheng Formula on mitochondrial morphology by PINK1/Parkin pathway in SH-SY5Y cells induced by MPP^(+)显示文摘Objective:Buyinqianzheng Formula(BYQZF)is clinically employed in traditional Chinese medicine to treat Parkinson's disease(PD)by improving mitochondrial dysfunction.However,the underlying mechanisms by which BYQZF affects mitochondrial morphology remain unknown.Therefore,we observed the effects of BYQZF on mitochondria from the perspective of the PINK1/Parkin pathway.Methods:Cell survival rates were assessed by Cell Counting Kit-8 assay.Expression levels of PINK1 and Parkin mRNA were examined by qRT-PCR.Protein expression levels of PINK1,PINK1-Ser228,Parkin,Parkin-Ser65,Drp1,and Drp1-Ser637 were examined by western blotting.PINK1,Parkin,and MitoTracker?Red CMXRos(MTR)were stained by triple-labeled immunofluorescence,and observed under laser confocal microscopy.Results:Cell survival rate,mitochondrial form factor,mean length and number of mitochondrial network branches,mitochondrial activity,m RNA expression levels of PINK1 and Parkin,and protein expression levels of PINK1,Parkin,and Drp1-Ser637 were reduced after 1-methyl-4-phenylpyridinium(MPP^(+))intervention.In contrast,Pearson's correlation coefficients between PINK1 and Parkin,and between Parkin and MTR,as well as protein expression levels of PINK1-Ser228,Parkin-Ser65,and Drp1 increased significantly after MPP^(+) intervention.Treatment with BYQZF increased cell survival rate,mitochondrial form factor,mean length and number of mitochondrial network branches,mitochondrial activity,m RNA expression levels of PINK1 and Parkin,and expression of PINK1,Parkin,and Drp1-Ser637 proteins.Pearson's correlation coefficients between PINK1 and Parkin,and between Parkin and MTR,as well as protein expression levels of PINK1-Ser228,Parkin-Ser65,and Drp1 decreased after BYQZF treatment.Conclusion:These results demonstrate that BYQZF has a protective effect on mitochondrial molecular mechanisms in the PD cell model,and the mechanism is related to the PINK1/Parkin pathway. | Haojie Ma Zhenyu Guo Cong Gai Cuicui Cheng Jinkun Zhang Yuxin Zhang Luping Yang Wandi Feng Yushan Gao Hongmei Sun | 2020 | Journal of Traditional Chinese Medical Sciences2020，7，3： | 3 |
| 3 | A fast,edge-preserving,distance-regularized model with bilateral filtering for oil spill segmentation of SAR images显示文摘Marine oil spills are among the most significant sources of marine pollution.Synthetic aperture radar(SAR)has been used to improve oil spill observations because of its advantages in oil spill detection and identification.However,speckle noise,weak boundaries,and intensity inhomogeneity often exist in the oil spill regions of SAR imagery,which will seriously aff ect the accurate identification of oil spills.To enhance marine oil spill segmentation of SAR images,a fast,edge-preserving framework based on the distance-regularized level set evolution(DRLSE)model was proposed.Specifically,a bilateral filter penalty term is designed and incorporated into the DRLSE energy function(BF-DRLSE)to preserve the edges of oil spills,and an adaptive initial box boundary was selected for the DRLSE model to reduce the operation time complexity.Two sets of RadarSat-2 SAR data were used to test the proposed method.The experimental results indicate that the bilateral filtering scheme incorporated into the energy function during level set evolution improved the stability of level set evolution.Compared with other methods,the proposed improved BF-DRLSE algorithm displayed a higher overall segmentation accuracy(97.83%).In addition,using an appropriate initial box boundary for the DRLSE method accelerated the global search process,improved the accuracy of oil spill segmentation,and reduced computational time.Therefore,the results suggest that the proposed framework is eff ective and applicable for marine oil spill segmentation. | Wandi WANG Hui SHENG Yanlong CHEN Shanwei LIU Jijun MAO Zhe ZENG Jianhua WAN | 2021 | Journal of Oceanology and Limnology2021，39，4： | 3 |
| 4 | Effects of investor sentiment on stock volatility:new evidences from multi-source data in China’s green stock markets显示文摘The effect of investor sentiment on stock volatility is a highly attractive research question in both the academic field and the real financial industry.With the proposal of China’s'dual carbon'target,green stocks have gradually become an essential branch of Chinese stock markets.Focusing on 106 stocks from the new energy,environmental protection,and carbon–neutral sectors,we construct two investor sentiment proxies using Internet text and stock trading data,respectively.The Internet sentiment is based on posts from Eastmoney Guba,and the trading sentiment comes from a variety of trading indicators.In addition,we divide the realized volatility into continuous and jump parts,and then investigate the effects of investor sentiment on different types of volatilities.Our empirical findings show that both sentiment indices impose significant positive impacts on realized,continuous,and jump volatilities,where trading sentiment is the main factor.We further explore the mediating effect of information asymmetry,measured by the volume-synchronized probability of informed trading(VPIN),on the path of investor sentiment affecting stock volatility.It is evidenced that investor sentiments are positively correlated with the VPIN,and they can affect volatilities through the VPIN.We then divide the total sample around the coronavirus disease 2019(COVID-19)pandemic.The empirical results reveal that the market volatility after the COVID-19 pandemic is more susceptible to investor sentiments,especially to Internet sentiment.Our study is of great significance for maintaining the stability of green stock markets and reducing market volatility. | Yang Gao Chengjie Zhao Bianxia Sun Wandi Zhao | 2022 | Financial Innovation2022，8，1： | 2 |
| 5 | Lithogenic risk factors in normal black volunteers,and black and white recurrent stone formers显示文摘 | Whalley N Martins M C Wandy K R C | | 0，，： | 1 |
| 6 | Long-term outcome for children with bacterial meningitis in rural papua new guinea显示文摘 | Wandi R Kiagi G Duke T | 2005 | J Trop Pediatr2005，51，1： | 1 |
| 7 | On a periodic maintenance problem显示文摘 | Wei Wandi | 1983 | Operations Research Letters1983，2，2： | 1 |
| 8 | Absence of ct-synuclein affects dopamine metabolism and synaptie markers in the striatum of aging mice显示文摘 | AI- Wandi A NInkina N Millership S | 2010 | Neurobiol Aging2010，31，： | 1 |
| 9 | Phosphorylation of Immunity-Related GTPases by a Toxoplasma gondii -Secreted Kinase Promotes Macrophage Survival and Virulence显示文摘 | Sarah J. Fentress Michael S. Behnke Ildiko R. Dunay Mona Mashayekhi Leah M. Rommereim Barbara A. Fox David J. Bzik Gregory A. Taylor Benjamin E. Turk Cheryl F. Lichti R. Reid Townsend Wei Qiu Raymond Hui Wandy L. Beatty L. David Sibley | 2010 | Cell Host & Microbe2010，，6： | 1 |
| 10 | Improved oxygen systems for childhood pneumonia:a multihospital effectiveness study in Papua New Guinea显示文摘 | Duke T Wandi F Jonathan M | 2008 | Lancet2008，372，9646： | 1 |
| 11 | Implementation of the family doctor service of blood pressure in elderly patients with essential hypertension related factors 显示文摘 | Yu Hui Pei Cai Yun Zeng Jian Xin Shi Lu Wandi Wang Dan Gong Xiaorui Qinchuan Zhao Yunpeng | 2012 | China Science2012，15，3： | 1 |
| 12 | Facile synthesis and in vivo bioimaging applications of porphyrin derivative-encapsulated polymer nanoparticles显示文摘Fluorescence(FL)imaging guided photodynamic therapy(PDT)is becoming highly desirable for personalized therapy and precision medicine.In this study,fluorescent polymer nanoparticles TCPP@PEI/PGA were facilely synthesized through electrostatic interaction-mediated self-assembly of porphyrins tetra(4-carboxyphenyl)porphine(TCPP)and polyethylenimine(PEI),and subsequent surface modification withγ-poly(glutamic acid)(γ-PGA).TCPP served a dual function as the FL imaging probe and the photosensitizer.The as-prepared TCPP@PEI/PGA nanoparticles showed excellent water-solubility and biocompatibility,while having outstanding capabilities of in vivo bioimaging and~1 O_(2) generation.FL bioimaging of mice and effective killing of CT 26 cells as well as CT 26 tumor-bearing mice upon laser irradiation were successfully demonstrated when using TCPP@PEI/PGA as theranostic nanoprobes.This study provides a simple but robust method to design and synthesize porphyrin-based polymer nanoparticles for theranostics. | Mengfei Hou Wandi Chen Junkai Zhao Deshen Dai Mo Yang Changqing Yi | 2022 | Chinese Chemical Letters2022，33，8： | 1 |
| 13 | Construction of a chimeric hepatitis C virus replicon based on a strain isolated from a chronic hepatitis C patient显示文摘Subgenomic repiicons of hepatitis C virus(HCV) have been widely used for studying HCV replication.Here,we report a new subgenomic replicon based on a strain isolated from a chronically infected patient.The coding sequence of HCV was recovered from a Chinese chronic hepatitis C patient displaying high serum HCV copy numbers.A consensus sequence designated as CCH strain was constructed based on the sequences of five clones and this was classified by sequence alignment as belonging to genotype 2a.The subgenomic replicon of CCH was replication-deficient in cell culture,due to dysfunctions in NS3 and NS5B.Various JFH1/CCH chimeric repiicons were constructed,and specific mutations were introduced.The introduction of mutations could partially restore the replication of chimeric repiicons.A replication-competent chimeric construct was finally obtained by the introduction of NS3 from JFH1 into the backbone of the CCH strain. | Huang Cao Wandi Zhu Qingxia Han Rongjuan Pei Xinwen Chen | 2014 | Virologica Sinica2014，29，1： | 1 |
| 14 | Visualization of urinary tract dilatation:value of single-shot MR urography显示文摘 | Reuther G Kiefer B Wandi E | 1997 | Eur Radiol1997，7，： | 1 |
| 15 | Catacondensed hexagonal systems with smaller numbers of kekule structures显示文摘 | Deogen J S Guo Xiaofeng Wei Wandi | 2003 | Theochem2003，639，： | 1 |
| 16 | Finite element a nalysis of misaligned rotors on oil film bearings显示文摘 | Sarkar S Wandi A Neogy S | 2010 | Sadhana2010，35，1： | 1 |
| 17 | Fuel technology looking to the future显示文摘 | Wandi Kencho Nuthall Keith | 2005 | Petroleum Review2005，59，704： | 1 |
| 18 | Long-term outcome for children with bacterial meningitis in rural papua new guinea显示文摘 | Wandi R Kiagi G Duke T | 2005 | J Trop Pediatr2005，51，1： | 1 |
| 19 | Visualization of Urinary Tract Dilatation: Value of Single-shot MR Urography 显示文摘 | Reuther G Kiefer B Wandi E | 1997 | Eur Radiol1997，7，8： | 1 |
| 20 | Treading New Ground显示文摘A Chinese entrepreneur explores business opportunities in Middle Eastern countries With the focus on the turmoil in Syria,few are concerned about whether business in the once prosperous but now war-torn country is still ongoing. | Jiang Wandi | 2017 | Beijing Review2017，60，29： | 0 |
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