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4篇 您的检索式:作者名="Qingxia Han"
    题名 作者 年代 出处 被引量
1A 15-year analysis of molecular epidemiology of avian infectious bronchitis coronavirus in China显示文摘Zongxi Han Chuyang Sun Baolong Yan Xiaonan Zhang Yu Wang Chengren Li Qingxia Zhang Yazhen Ma Yuhao Shao Qiaoran Liu Xiangang Kong Shengwang Liu 2010Infection Genetics and Evolution2010,,1:2
2A 15-year analysis of molecular epidemiology of avian infectious bronchitis coronavirus in China显示文摘Zongxi Han Chuyang Sun Baolong Yan Xiaonan Zhang Yu Wang Chengren Li Qingxia Zhang Yazhen Ma Yuhao Shao Qiaoran Liu Xiangang Kong Shengwang Liu 2010Infection Genetics and Evolution2010,,1:2
3Construction of a chimeric hepatitis C virus replicon based on a strain isolated from a chronic hepatitis C patient显示文摘Subgenomic repiicons of hepatitis C virus(HCV) have been widely used for studying HCV replication.Here,we report a new subgenomic replicon based on a strain isolated from a chronically infected patient.The coding sequence of HCV was recovered from a Chinese chronic hepatitis C patient displaying high serum HCV copy numbers.A consensus sequence designated as CCH strain was constructed based on the sequences of five clones and this was classified by sequence alignment as belonging to genotype 2a.The subgenomic replicon of CCH was replication-deficient in cell culture,due to dysfunctions in NS3 and NS5B.Various JFH1/CCH chimeric repiicons were constructed,and specific mutations were introduced.The introduction of mutations could partially restore the replication of chimeric repiicons.A replication-competent chimeric construct was finally obtained by the introduction of NS3 from JFH1 into the backbone of the CCH strain.Huang Cao Wandi Zhu Qingxia Han Rongjuan Pei Xinwen Chen 2014Virologica Sinica2014,29,1:1
4New evidence on the antiviral role of RNA interference in mammals显示文摘Unique among the multitude of host defense systems evolved to combat viral pathogens,RNA molecules serve as both the inducer and the specificity determinant of the antiviral immunity mechanism mediated by RNA interference(RNAi).Consistently withQingxia Han Shou-Wei Ding 2017National Science Review2017,4,5:0
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